Dysregulation of Mitochondrial Quality Control Processes Contribute to Sarcopenia in a Mouse Model of Premature Aging

Skeletal muscle aging and the mitochondrion

(2013) Matthew L. Johnson et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The impact of aging on mitochondrial function and biogenesis pathways in skeletal muscle of sedentary high- and low-functioning elderly individuals

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Mitochondrial pathways in sarcopenia of aging and disuse muscle atrophy

(2012) Riccardo Calvani et al.   BIOLOGICAL CHEMISTRY

Increased mitochondrial biogenesis in muscle improves aging phenotypes in the mtDNA mutator mouse

(2012) Lloye M. Dillon et al.   HUMAN MOLECULAR GENETICS

Impaired mitochondrial respiration and decreased fatigue resistance followed by severe muscle weakness in skeletal muscle of mitochondrial DNA mutator mice

(2012) Takashi Yamada et al.   JOURNAL OF PHYSIOLOGY-LONDON

Selective autophagy mediated by autophagic adapter proteins

(2011) Terje Johansen et al.   Autophagy

PKB signaling and atrogene expression in skeletal muscle of aged mice

(2011) Megan Gaugler et al.   JOURNAL OF APPLIED PHYSIOLOGY

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Endurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator mice

(2011) A. Safdar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Somatic Mitochondrial DNA Mutations in Mammalian Aging

(2010) Nils-Göran Larsson   Annual Review of Biochemistry

Mitochondrial Fusion Is Required for mtDNA Stability in Skeletal Muscle and Tolerance of mtDNA Mutations

(2010) Hsiuchen Chen et al.   CELL

Mitochondrial Biogenesis and Fragmentation as Regulators of Muscle Protein Degradation

(2010) Vanina Romanello et al.   CURRENT HYPERTENSION REPORTS

Mitochondrial fission and remodelling contributes to muscle atrophy

(2010) Vanina Romanello et al.   EMBO JOURNAL

New insights into the role of mitochondria in aging: mitochondrial dynamics and more

(2010) A. Y. Seo et al.   JOURNAL OF CELL SCIENCE

Mitochondrial DNA Mutations Induce Mitochondrial Dysfunction, Apoptosis and Sarcopenia in Skeletal Muscle of Mitochondrial DNA Mutator Mice

(2010) Asimina Hiona et al.   PLoS One

The Association of AMPK with ULK1 Regulates Autophagy

(2010) Jong Woo Lee et al.   PLoS One

Aging: Central role for autophagy and the lysosomal degradative system

(2009) Yogendra S. Rajawat et al.   AGEING RESEARCH REVIEWS

The role of PGC-1α on mitochondrial function and apoptotic susceptibility in muscle

(2009) Peter J. Adhihetty et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Random Point Mutations with Major Effects on Protein-Coding Genes Are the Driving Force behind Premature Aging in mtDNA Mutator Mice

(2009) Daniel Edgar et al.   Cell Metabolism

Age-related changes of cell death pathways in rat extraocular muscle

(2009) Colleen A. McMullen et al.   EXPERIMENTAL GERONTOLOGY

Skeletal muscle autophagy and apoptosis during aging: Effects of calorie restriction and life-long exercise

(2009) Stephanie Eva Wohlgemuth et al.   EXPERIMENTAL GERONTOLOGY

Increased muscle PGC-1  expression protects from sarcopenia and metabolic disease during aging

(2009) T. Wenz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NRF-1 is the major transcription factor regulating the expression of the human TOMM34 gene

(2008) José R. Blesa et al.   Biochemistry and Cell Biology

Mitochondrial fusion, fission and autophagy as a quality control axis: The bioenergetic view

(2008) Gilad Twig et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice

(2008) Marc Vermulst et al.   NATURE GENETICS