Soluble amyloid-β oligomers as synaptotoxins leading to cognitive impairment in Alzheimer’s disease
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Title
Soluble amyloid-β oligomers as synaptotoxins leading to cognitive impairment in Alzheimer’s disease
Authors
Keywords
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Journal
Frontiers in Cellular Neuroscience
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2015-05-26
DOI
10.3389/fncel.2015.00191
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Note: Only part of the references are listed.- Picomolar Amyloid-β Peptides Enhance Spontaneous Astrocyte Calcium Transients
- (2018) Linda Lee et al. JOURNAL OF ALZHEIMERS DISEASE
- Structural Diversity of Alzheimer's Disease Amyloid-β Dimers and Their Role in Oligomerization and Fibril Formation
- (2018) Igor F. Tsigelny et al. JOURNAL OF ALZHEIMERS DISEASE
- Amyloid β oligomers in Alzheimer’s disease pathogenesis, treatment, and diagnosis
- (2015) Kirsten L. Viola et al. ACTA NEUROPATHOLOGICA
- 2015 Alzheimer's disease facts and figures
- (2015) Alzheimers & Dementia
- Fyn inhibition rescues established memory and synapse loss in Alzheimer mice
- (2015) Adam C. Kaufman et al. ANNALS OF NEUROLOGY
- Neuronal amyloid-β accumulation within cholinergic basal forebrain in ageing and Alzheimer’s disease
- (2015) Alaina Baker-Nigh et al. BRAIN
- Amyloid β oligomer-induced ERK1/2-dependent serine 636/639 phosphorylation of insulin receptor substrate-1 impairs insulin signaling and glycogen storage in human astrocytes
- (2015) Qinghua Zhang et al. GENE
- Amyloid β 1-42 Induces Hypometabolism in Human Stem Cell-Derived Neuron and Astrocyte Networks
- (2015) Marta A Tarczyluk et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Long-Term Memory Formation in Drosophila Requires Training-Dependent Glial Transcription
- (2015) M. Matsuno et al. JOURNAL OF NEUROSCIENCE
- Dendritic and axonal mechanisms of Ca2+ elevation impair BDNF transport in Aβ oligomer–treated hippocampal neurons
- (2015) Kathlyn J. Gan et al. MOLECULAR BIOLOGY OF THE CELL
- Alzheimer's disease is associated with altered expression of genes involved in immune response and mitochondrial processes in astrocytes
- (2015) Shobana Sekar et al. NEUROBIOLOGY OF AGING
- Modulation of insulin signaling rescues BDNF transport defects independent of tau in amyloid-β oligomer-treated hippocampal neurons
- (2015) Oliver Takach et al. NEUROBIOLOGY OF AGING
- Alzheimer's Aβ interacts with cellular prion protein inducing neuronal membrane damage and synaptotoxicity
- (2015) Christian Peters et al. NEUROBIOLOGY OF AGING
- Il10 Deficiency Rebalances Innate Immunity to Mitigate Alzheimer-Like Pathology
- (2015) Marie-Victoire Guillot-Sestier et al. NEURON
- d-serine levels in Alzheimer’s disease: implications for novel biomarker development
- (2015) C Madeira et al. Translational Psychiatry
- Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer’s disease
- (2015) Amy M Pooler et al. Acta Neuropathologica Communications
- A novel mechanism for cyclic adenosine monophosphate-mediated memory formation: Role of amyloid beta
- (2014) Roberta Ricciarelli et al. ANNALS OF NEUROLOGY
- Translational Control in Synaptic Plasticity and Cognitive Dysfunction
- (2014) Shelly A. Buffington et al. Annual Review of Neuroscience
- Aβ dimers differ from monomers in structural propensity, aggregation paths and population of synaptotoxic assemblies
- (2014) Tiernan T. O’Malley et al. BIOCHEMICAL JOURNAL
- Interaction of Alzheimer’s β-Amyloid Peptides with Cholesterol: Mechanistic Insights into Amyloid Pore Formation
- (2014) Coralie Di Scala et al. BIOCHEMISTRY
- Role of the Fast Kinetics of Pyroglutamate-Modified Amyloid-β Oligomers in Membrane Binding and Membrane Permeability
- (2014) Joon Lee et al. BIOCHEMISTRY
- Rare Individual Amyloid-β Oligomers Act on Astrocytes to Initiate Neuronal Damage
- (2014) Priyanka Narayan et al. BIOCHEMISTRY
- High molecular mass assemblies of amyloid-β oligomers bind prion protein in patients with Alzheimer’s disease
- (2014) Frank Dohler et al. BRAIN
- Axonally Synthesized ATF4 Transmits a Neurodegenerative Signal across Brain Regions
- (2014) Jimena Baleriola et al. CELL
- Leptin inhibits amyloid β-protein fibrillogenesis by decreasing GM1 gangliosides on the neuronal cell surface through PI3K/Akt/mTOR pathway
- (2014) Naoki Yamamoto et al. JOURNAL OF NEUROCHEMISTRY
- Genetic Modulation of Soluble A Rescues Cognitive and Synaptic Impairment in a Mouse Model of Alzheimer's Disease
- (2014) S. W. Fowler et al. JOURNAL OF NEUROSCIENCE
- In vivo Activation of Wnt Signaling Pathway Enhances Cognitive Function of Adult Mice and Reverses Cognitive Deficits in an Alzheimer's Disease Model
- (2014) J. Y. Vargas et al. JOURNAL OF NEUROSCIENCE
- Activity-Dependent Tau Protein Translocation to Excitatory Synapse Is Disrupted by Exposure to Amyloid-Beta Oligomers
- (2014) M. L. Frandemiche et al. JOURNAL OF NEUROSCIENCE
- Alzheimer's Disease-Like Pathology Induced by Amyloid-β Oligomers in Nonhuman Primates
- (2014) Leticia Forny-Germano et al. JOURNAL OF NEUROSCIENCE
- A three-dimensional human neural cell culture model of Alzheimer’s disease
- (2014) Se Hoon Choi et al. NATURE
- Towards non-invasive diagnostic imaging of early-stage Alzheimer's disease
- (2014) Kirsten L. Viola et al. Nature Nanotechnology
- Tau promotes neurodegeneration through global chromatin relaxation
- (2014) Bess Frost et al. NATURE NEUROSCIENCE
- Translational control of mGluR-dependent long-term depression and object-place learning by eIF2α
- (2014) Gonzalo Viana Di Prisco et al. NATURE NEUROSCIENCE
- Epigenetic suppression of neuroligin 1 underlies amyloid-induced memory deficiency
- (2014) Bihua Bie et al. NATURE NEUROSCIENCE
- Soluble Aβ Oligomers Are Rapidly Sequestered from Brain ISF In Vivo and Bind GM1 Ganglioside on Cellular Membranes
- (2014) Soyon Hong et al. NEURON
- Alzheimer's Therapeutics Targeting Amyloid Beta 1–42 Oligomers II: Sigma-2/PGRMC1 Receptors Mediate Abeta 42 Oligomer Binding and Synaptotoxicity
- (2014) Nicholas J. Izzo et al. PLoS One
- Alzheimer's Therapeutics Targeting Amyloid Beta 1–42 Oligomers I: Abeta 42 Oligomer Binding to Specific Neuronal Receptors Is Displaced by Drug Candidates That Improve Cognitive Deficits
- (2014) Nicholas J. Izzo et al. PLoS One
- Toward a unified therapeutics approach targeting putative amyloid- oligomer receptors
- (2014) C. R. Overk et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Blockade of EphA4 signaling ameliorates hippocampal synaptic dysfunctions in mouse models of Alzheimer’s disease
- (2014) Amy K. Y. Fu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Is Alzheimer's disease related to metabolic syndrome? A Wnt signaling conundrum
- (2014) Juvenal A. Ríos et al. PROGRESS IN NEUROBIOLOGY
- mGlu5 receptors and cellular prion protein mediate amyloid-β-facilitated synaptic long-term depression in vivo
- (2014) Neng-Wei Hu et al. Nature Communications
- Metabotropic glutamate receptor 5 knockout reduces cognitive impairment and pathogenesis in a mouse model of Alzheimer's disease
- (2014) Alison Hamilton et al. Molecular Brain
- Synaptic Health
- (2014) John H. Morrison et al. JAMA Psychiatry
- Different effects of Alzheimer's peptide Aβ(1–40) oligomers and fibrils on supported lipid membranes
- (2013) Claudio Canale et al. BIOPHYSICAL CHEMISTRY
- Brain amyloid-β oligomers in ageing and Alzheimer’s disease
- (2013) Sylvain E. Lesné et al. BRAIN
- Dissecting phenotypic traits linked to human resilience to Alzheimer’s pathology
- (2013) Beatriz G. Perez-Nievas et al. BRAIN
- TNF-α Mediates PKR-Dependent Memory Impairment and Brain IRS-1 Inhibition Induced by Alzheimer’s β-Amyloid Oligomers in Mice and Monkeys
- (2013) Mychael V. Lourenco et al. Cell Metabolism
- Modeling Alzheimer’s Disease with iPSCs Reveals Stress Phenotypes Associated with Intracellular Aβ and Differential Drug Responsiveness
- (2013) Takayuki Kondo et al. Cell Stem Cell
- Amyloid-β oligomers induce synaptic damage via Tau-dependent microtubule severing by TTLL6 and spastin
- (2013) Hans Zempel et al. EMBO JOURNAL
- Brain interstitial oligomeric amyloid β increases with age and is resistant to clearance from brain in a mouse model of Alzheimer's disease
- (2013) Shuko Takeda et al. FASEB JOURNAL
- Partitioning and confinement of GM1 ganglioside induced by amyloid aggregates
- (2013) Martino Calamai et al. FEBS LETTERS
- An N-terminal Fragment of the Prion Protein Binds to Amyloid-β Oligomers and Inhibits Their Neurotoxicityin Vivo
- (2013) Brian R. Fluharty et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Alzheimer’s disease and insulin resistance: translating basic science into clinical applications
- (2013) Fernanda G. De Felice JOURNAL OF CLINICAL INVESTIGATION
- Specific Domains of Aβ Facilitate Aggregation on and Association with Lipid Bilayers
- (2013) Elizabeth A. Yates et al. JOURNAL OF MOLECULAR BIOLOGY
- Systemic vaccination with anti-oligomeric monoclonal antibodies improves cognitive function by reducing Aβ deposition and tau pathology in 3xTg-AD mice
- (2013) Suhail Rasool et al. JOURNAL OF NEUROCHEMISTRY
- Amyloid- Peptide Oligomers Disrupt Axonal Transport through an NMDA Receptor-Dependent Mechanism That Is Mediated by Glycogen Synthase Kinase 3 in Primary Cultured Hippocampal Neurons
- (2013) H. Decker et al. JOURNAL OF NEUROSCIENCE
- Sustained Interleukin-1 Overexpression Exacerbates Tau Pathology Despite Reduced Amyloid Burden in an Alzheimer's Mouse Model
- (2013) S. Ghosh et al. JOURNAL OF NEUROSCIENCE
- Memantine Rescues Transient Cognitive Impairment Caused by High-Molecular-Weight A Oligomers But Not the Persistent Impairment Induced by Low-Molecular-Weight Oligomers
- (2013) C. P. Figueiredo et al. JOURNAL OF NEUROSCIENCE
- A Transgenic Alzheimer Rat with Plaques, Tau Pathology, Behavioral Impairment, Oligomeric A , and Frank Neuronal Loss
- (2013) R. M. Cohen et al. JOURNAL OF NEUROSCIENCE
- Tau Accumulation Activates the Unfolded Protein Response by Impairing Endoplasmic Reticulum-Associated Degradation
- (2013) J. F. Abisambra et al. JOURNAL OF NEUROSCIENCE
- Amyloid-β oligomers induce tau-independent disruption of BDNF axonal transport via calcineurin activation in cultured hippocampal neurons
- (2013) Elisa M. Ramser et al. MOLECULAR BIOLOGY OF THE CELL
- Suppression of eIF2α kinases alleviates Alzheimer's disease–related plasticity and memory deficits
- (2013) Tao Ma et al. NATURE NEUROSCIENCE
- Metabotropic Glutamate Receptor 5 Is a Coreceptor for Alzheimer Aβ Oligomer Bound to Cellular Prion Protein
- (2013) Ji Won Um et al. NEURON
- A Luminex Assay Detects Amyloid β Oligomers in Alzheimer’s Disease Cerebrospinal Fluid
- (2013) Adrianna Z. Herskovits et al. PLoS One
- Quantitative analysis of the time course of Aβ oligomerization and subsequent growth steps using tetramethylrhodamine-labeled Aβ
- (2013) Kanchan Garai et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Canonical Wnt signaling protects hippocampal neurons from Aβ oligomers: role of non-canonical Wnt-5a/Ca2+ in mitochondrial dynamics
- (2013) Carmen Silva-Alvarez et al. Frontiers in Cellular Neuroscience
- Wnt signaling in the regulation of adult hippocampal neurogenesis
- (2013) Lorena Varela-Nallar et al. Frontiers in Cellular Neuroscience
- Biochemistry and Cell Biology of Tau Protein in Neurofibrillary Degeneration
- (2013) E.-M. Mandelkow et al. Cold Spring Harbor Perspectives in Medicine
- Animal Models of Alzheimer Disease
- (2013) F. M. LaFerla et al. Cold Spring Harbor Perspectives in Medicine
- Exosomes neutralize synaptic-plasticity-disrupting activity of Aβ assemblies in vivo
- (2013) Kyongman An et al. Molecular Brain
- Seizures and Epileptiform Activity in the Early Stages of Alzheimer Disease
- (2013) Keith A. Vossel et al. JAMA Neurology
- Synapse-Binding Subpopulations of Aβ Oligomers Sensitive to Peptide Assembly Blockers and scFv Antibodies
- (2012) Pauline T. Velasco et al. ACS Chemical Neuroscience
- The levels of water-soluble and triton-soluble Aβ are increased in Alzheimer's disease brain
- (2012) Jessica M. McDonald et al. BRAIN RESEARCH
- Oligomers of beta-amyloid protein (Aβ1-42) induce the activation of cyclooxygenase-2 in astrocytes via an interaction with interleukin-1beta, tumour necrosis factor-alpha, and a nuclear factor kappa-B mechanism in the rat brain
- (2012) I. Carrero et al. EXPERIMENTAL NEUROLOGY
- Neuronal receptors as targets for the action of amyloid-beta protein (Aβ) in the brain
- (2012) Aarti N. Patel et al. EXPERT REVIEWS IN MOLECULAR MEDICINE
- Amyloid-β Oligomers Induce Differential Gene Expression in Adult Human Brain Slices
- (2012) Adriano Sebollela et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer’s disease–associated Aβ oligomers
- (2012) Theresa R. Bomfim et al. JOURNAL OF CLINICAL INVESTIGATION
- Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline
- (2012) Konrad Talbot et al. JOURNAL OF CLINICAL INVESTIGATION
- Brain insulin resistance accelerates Aβ fibrillogenesis by inducing GM1 ganglioside clustering in the presynaptic membranes
- (2012) Naoki Yamamoto et al. JOURNAL OF NEUROCHEMISTRY
- Neurotoxicity and Memory Deficits Induced by Soluble Low-Molecular-Weight Amyloid- 1-42 Oligomers Are Revealed In Vivo by Using a Novel Animal Model
- (2012) J. Brouillette et al. JOURNAL OF NEUROSCIENCE
- PPAR /RXR -Induced and CD36-Mediated Microglial Amyloid- Phagocytosis Results in Cognitive Improvement in Amyloid Precursor Protein/Presenilin 1 Mice
- (2012) M. Yamanaka et al. JOURNAL OF NEUROSCIENCE
- Soluble A Promotes Wild-Type Tau Pathology In Vivo
- (2012) M. A. Chabrier et al. JOURNAL OF NEUROSCIENCE
- Loss of Interleukin Receptor-Associated Kinase 4 Signaling Suppresses Amyloid Pathology and Alters Microglial Phenotype in a Mouse Model of Alzheimer's Disease
- (2012) B. Cameron et al. JOURNAL OF NEUROSCIENCE
- Sortilin is required for toxic action of Aβ oligomers (AβOs): Extracellular AβOs trigger apoptosis, and intraneuronal AβOs impair degradation pathways
- (2012) Ayumi Takamura et al. LIFE SCIENCES
- Absence of amyloid β oligomers at the postsynapse and regulated synaptic Zn2+ in cognitively intact aged individuals with Alzheimer’s disease neuropathology
- (2012) Nicole L Bjorklund et al. Molecular Neurodegeneration
- Amyloid-β oligomers link depressive-like behavior and cognitive deficits in mice
- (2012) J H Ledo et al. MOLECULAR PSYCHIATRY
- Probing sporadic and familial Alzheimer’s disease using induced pluripotent stem cells
- (2012) Mason A. Israel et al. NATURE
- The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes
- (2012) Iryna Benilova et al. NATURE NEUROSCIENCE
- Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons
- (2012) Ji Won Um et al. NATURE NEUROSCIENCE
- The many faces of insulin-like peptide signalling in the brain
- (2012) Ana M. Fernandez et al. NATURE REVIEWS NEUROSCIENCE
- Activity-Dependent Proteolytic Cleavage of Neuroligin-1
- (2012) Kunimichi Suzuki et al. NEURON
- JNK3 Perpetuates Metabolic Stress Induced by Aβ Peptides
- (2012) Sung Ok Yoon et al. NEURON
- Alzheimer Aβ peptide interactions with lipid membranes
- (2012) Florentina Tofoleanu et al. Prion
- Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model
- (2012) P. E. Sanchez et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Alzheimer’s disease Aβ assemblies mediating rapid disruption of synaptic plasticity and memory
- (2012) Igor Klyubin et al. Molecular Brain
- Amyloid-β associated volume loss occurs only in the presence of phospho-tau
- (2011) Rahul S. Desikan et al. ANNALS OF NEUROLOGY
- Inflammatory Mechanisms in Obesity
- (2011) Margaret F. Gregor et al. Annual Review of Immunology
- Aβ42 oligomers, but not fibrils, simultaneously bind to and cause damage to ganglioside-containing lipid membranes
- (2011) Thomas L. Williams et al. BIOCHEMICAL JOURNAL
- The Synaptic Protein Neuroligin-1 Interacts with the Amyloid β-Peptide. Is There a Role in Alzheimer’s Disease?
- (2011) Margarita C. Dinamarca et al. BIOCHEMISTRY
- Suppression of PKR Promotes Network Excitability and Enhanced Cognition by Interferon-γ-Mediated Disinhibition
- (2011) Ping Jun Zhu et al. CELL
- Aβ Oligomers Induce Glutamate Release from Hippocampal Neurons
- (2011) J. Brito-Moreira et al. Current Alzheimer Research
- Transgenic Mice as a Model of Pre-Clinical Alzheimers Disease
- (2011) M. T. Ferretti et al. Current Alzheimer Research
- Modeling familial Alzheimer's disease with induced pluripotent stem cells
- (2011) Takuya Yagi et al. HUMAN MOLECULAR GENETICS
- Intra-membrane Oligomerization and Extra-membrane Oligomerization of Amyloid-β Peptide Are Competing Processes as a Result of Distinct Patterns of Motif Interplay
- (2011) Yi-Jiong Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Soluble Oligomers of Amyloid-β Peptide Disrupt Membrane Trafficking of α-Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid Receptor Contributing to Early Synapse Dysfunction
- (2011) Alfredo J. Miñano-Molina et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Two Distinct Amyloid β-Protein (Aβ) Assembly Pathways Leading to Oligomers and Fibrils Identified by Combined Fluorescence Correlation Spectroscopy, Morphology, and Toxicity Analyses
- (2011) Satoko Matsumura et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Amyloid-beta oligomers increase the localization of prion protein at the cell surface
- (2011) Fabiana A. Caetano et al. JOURNAL OF NEUROCHEMISTRY
- Reduced levels of the tyrosine phosphatase STEP block beta amyloid-mediated GluA1/GluA2 receptor internalization
- (2011) Yongfang Zhang et al. JOURNAL OF NEUROCHEMISTRY
- A monoclonal antibody against synthetic Aβ dimer assemblies neutralizes brain-derived synaptic plasticity-disrupting Aβ
- (2011) Brian O’Nuallain et al. JOURNAL OF NEUROCHEMISTRY
- The World of Dementia Beyond 2020
- (2011) Henry Brodaty et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Amyloid beta dimers/trimers potently induce cofilin-actin rods that are inhibited by maintaining cofilin-phosphorylation
- (2011) Richard C Davis et al. Molecular Neurodegeneration
- Resolving controversies on the path to Alzheimer's therapeutics
- (2011) Dennis J Selkoe NATURE MEDICINE
- An overlooked neurotoxic species in Alzheimer's disease
- (2011) Iryna Benilova et al. NATURE NEUROSCIENCE
- Different β-amyloid oligomer assemblies in Alzheimer brains correlate with age of disease onset and impaired cholinergic activity
- (2011) Fuxiang Bao et al. NEUROBIOLOGY OF AGING
- The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer’s disease
- (2011) Sergio T. Ferreira et al. NEUROBIOLOGY OF LEARNING AND MEMORY
- Linking Amyloid-ß and Tau: Amyloid-ß Induced Synaptic Dysfunction via Local Wreckage of the Neuronal Cytoskeleton
- (2011) Hans Zempel et al. Neurodegenerative Diseases
- β-amyloid oligomers and prion protein
- (2011) Gianluigi Forloni et al. Prion
- Soluble amyloid -protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration
- (2011) M. Jin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Endogenous amyloid-β is necessary for hippocampal synaptic plasticity and memory
- (2010) Daniela Puzzo et al. ANNALS OF NEUROLOGY
- Amyloid β-Peptide Oligomers Stimulate RyR-Mediated Ca2+ Release Inducing Mitochondrial Fragmentation in Hippocampal Neurons and Prevent RyR-Mediated Dendritic Spine Remodeling Produced by BDNF
- (2010) Andrea C. Paula-Lima et al. ANTIOXIDANTS & REDOX SIGNALING
- Beneficial effect of human anti-amyloid-β active immunization on neurite morphology and tau pathology
- (2010) Alberto Serrano-Pozo et al. BRAIN
- Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models
- (2010) Lars M. Ittner et al. CELL
- High-molecular-weight β-amyloid oligomers are elevated in cerebrospinal fluid of Alzheimer patients
- (2010) Hiroaki Fukumoto et al. FASEB JOURNAL
- Metabotropic glutamate receptors transduce signals for neurite outgrowth after binding of the prion protein to laminin γ1 chain
- (2010) Flavio H. Beraldo et al. FASEB JOURNAL
- Astrocytic Aβ1-42 uptake is determined by Aβ-aggregation state and the presence of amyloid-associated proteins
- (2010) Henrietta M. Nielsen et al. GLIA
- Phenylbutyrate rescues dendritic spine loss associated with memory deficits in a mouse model of Alzheimer disease
- (2010) Ana Ricobaraza et al. HIPPOCAMPUS
- Activation of D1/D5 Dopamine Receptors Protects Neurons from Synapse Dysfunction Induced by Amyloid-β Oligomers
- (2010) Sofia Jürgensen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- N-Methyl-d-aspartate receptors are required for synaptic targeting of Alzheimer’s toxic amyloid-β peptide oligomers
- (2010) Helena Decker et al. JOURNAL OF NEUROCHEMISTRY
- Ganglioside-mediated aggregation of amyloid β-proteins (Aβ): comparison between Aβ-(1-42) and Aβ-(1-40)
- (2010) Mariko Ogawa et al. JOURNAL OF NEUROCHEMISTRY
- Memory Impairment in Transgenic Alzheimer Mice Requires Cellular Prion Protein
- (2010) D. A. Gimbel et al. JOURNAL OF NEUROSCIENCE
- Amyloid -Protein Dimers Rapidly Form Stable Synaptotoxic Protofibrils
- (2010) B. O'Nuallain et al. JOURNAL OF NEUROSCIENCE
- Reimagining Alzheimer's Disease--An Age-Based Hypothesis
- (2010) K. Herrup JOURNAL OF NEUROSCIENCE
- A -Mediated NMDA Receptor Endocytosis in Alzheimer's Disease Involves Ubiquitination of the Tyrosine Phosphatase STEP61
- (2010) P. Kurup et al. JOURNAL OF NEUROSCIENCE
- Amyloid Induces the Morphological Neurodegenerative Triad of Spine Loss, Dendritic Simplification, and Neuritic Dystrophies through Calcineurin Activation
- (2010) H.-Y. Wu et al. JOURNAL OF NEUROSCIENCE
- A Oligomers Cause Localized Ca2+ Elevation, Missorting of Endogenous Tau into Dendrites, Tau Phosphorylation, and Destruction of Microtubules and Spines
- (2010) H. Zempel et al. JOURNAL OF NEUROSCIENCE
- A Mouse Model of Amyloid Oligomers: Their Contribution to Synaptic Alteration, Abnormal Tau Phosphorylation, Glial Activation, and Neuronal Loss In Vivo
- (2010) T. Tomiyama et al. JOURNAL OF NEUROSCIENCE
- The prion protein as a receptor for amyloid-β
- (2010) Helmut W. Kessels et al. NATURE
- Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease
- (2010) Martin Fuhrmann et al. NATURE NEUROSCIENCE
- Cognitive effects of cell-derived and synthetically derived Aβ oligomers
- (2010) Miranda N. Reed et al. NEUROBIOLOGY OF AGING
- Deleterious Effects of Amyloid β Oligomers Acting as an Extracellular Scaffold for mGluR5
- (2010) Marianne Renner et al. NEURON
- ADDLs and the signaling web that leads to Alzheimer’s disease
- (2010) Grant A. Krafft et al. NEUROPHARMACOLOGY
- Amyloid-β Triggers the Release of Neuronal Hexokinase 1 from Mitochondria
- (2010) Leonardo M. Saraiva et al. PLoS One
- Synthetic amyloid- oligomers impair long-term memory independently of cellular prion protein
- (2010) C. Balducci et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Amyloid β-Protein Aggregation Produces Highly Reproducible Kinetic Data and Occurs by a Two-Phase Process
- (2009) Erik Hellstrand et al. ACS Chemical Neuroscience
- The Unfolded Protein Response Is Activated in Pretangle Neurons in Alzheimer's Disease Hippocampus
- (2009) Jeroen J.M. Hoozemans et al. AMERICAN JOURNAL OF PATHOLOGY
- A Specific Enzyme-Linked Immunosorbent Assay for Measuring β-Amyloid Protein Oligomers in Human Plasma and Brain Tissue of Patients With Alzheimer Disease
- (2009) Weiming Xia et al. ARCHIVES OF NEUROLOGY
- Inhibition of Calcineurin-mediated Endocytosis and α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors Prevents Amyloid β Oligomer-induced Synaptic Disruption
- (2009) Wei-Qin Zhao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Recombinant Amyloid-β Peptide Aβ1–42 Aggregates Faster and Is More Neurotoxic than Synthetic Aβ1–42
- (2009) Verena H. Finder et al. JOURNAL OF MOLECULAR BIOLOGY
- Picomolar Amyloid- Positively Modulates Synaptic Plasticity and Memory in Hippocampus
- (2009) D. Puzzo et al. JOURNAL OF NEUROSCIENCE
- -Amyloid Oligomers Induce Phosphorylation of Tau and Inactivation of Insulin Receptor Substrate via c-Jun N-Terminal Kinase Signaling: Suppression by Omega-3 Fatty Acids and Curcumin
- (2009) Q.-L. Ma et al. JOURNAL OF NEUROSCIENCE
- Detection and Identification of Bioanalytes with High Resolution LSPR Spectroscopy and MALDI Mass Spectrometry
- (2009) Jeffrey N. Anker et al. Journal of Physical Chemistry C
- Amyloid beta mediates memory formation
- (2009) A. Garcia-Osta et al. LEARNING & MEMORY
- Activation of Wnt signaling by lithium and rosiglitazone reduced spatial memory impairment and neurodegeneration in brains of an APPswe/PSEN1ΔE9 mouse model of Alzheimer's disease
- (2009) E M Toledo et al. MOLECULAR PSYCHIATRY
- Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers
- (2009) Juha Laurén et al. NATURE
- Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer's disease
- (2009) Summer L. Bernstein et al. Nature Chemistry
- Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology
- (2009) Fiona E. McAlpine et al. NEUROBIOLOGY OF DISEASE
- Biochemical and immunohistochemical analysis of an Alzheimer's disease mouse model reveals the presence of multiple cerebral Aβ assembly forms throughout life
- (2009) Ganesh M. Shankar et al. NEUROBIOLOGY OF DISEASE
- Soluble Oligomers of Amyloid β Protein Facilitate Hippocampal Long-Term Depression by Disrupting Neuronal Glutamate Uptake
- (2009) Shaomin Li et al. NEURON
- Phenylbutyrate Ameliorates Cognitive Deficit and Reduces Tau Pathology in an Alzheimer's Disease Mouse Model
- (2009) Ana Ricobaraza et al. NEUROPSYCHOPHARMACOLOGY
- Oligomeric amyloid associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques
- (2009) R. M. Koffie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Protection of synapses against Alzheimer's-linked toxins: Insulin signaling prevents the pathogenic binding of Aβ oligomers
- (2009) Fernanda G. De Felice et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Oligomers of the amyloid-β protein disrupt working memory: Confirmation with two behavioral procedures
- (2008) Alan Poling et al. BEHAVIOURAL BRAIN RESEARCH
- Soluble amyloid- peptides potently disrupt hippocampal synaptic plasticity in the absence of cerebrovascular dysfunction in vivo
- (2008) N.-W. Hu et al. BRAIN
- Amyloid-β Binds to the Extracellular Cysteine-rich Domain of Frizzled and Inhibits Wnt/β-Catenin Signaling
- (2008) Margaret H. Magdesian et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Prion protein attenuates excitotoxicity by inhibiting NMDA receptors
- (2008) Houman Khosravani et al. JOURNAL OF CELL BIOLOGY
- Frizzled-1 is involved in the neuroprotective effect of Wnt3a against Aβ oligomers
- (2008) Marcelo A. Chacón et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Amyloid- Peptide (A ) Neurotoxicity Is Modulated by the Rate of Peptide Aggregation: A Dimers and Trimers Correlate with Neurotoxicity
- (2008) L. W. Hung et al. JOURNAL OF NEUROSCIENCE
- Amyloid Protein Dimer-Containing Human CSF Disrupts Synaptic Plasticity: Prevention by Systemic Passive Immunization
- (2008) I. Klyubin et al. JOURNAL OF NEUROSCIENCE
- Microglial Dysfunction and Defective -Amyloid Clearance Pathways in Aging Alzheimer's Disease Mice
- (2008) S. E. Hickman et al. JOURNAL OF NEUROSCIENCE
- Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
- (2008) Ganesh M Shankar et al. NATURE MEDICINE
- Physiology of the Prion Protein
- (2008) Rafael Linden et al. PHYSIOLOGICAL REVIEWS
- Amyloid beta oligomers induce impairment of neuronal insulin receptors
- (2007) Wei-Qin Zhao et al. FASEB JOURNAL
- Alzheimer's disease-type neuronal tau hyperphosphorylation induced by Aβ oligomers
- (2007) Fernanda G. De Felice et al. NEUROBIOLOGY OF AGING
- Vaccination with soluble Aβ oligomers generates toxicity-neutralizing antibodies
- (2003) Mary P. Lambert et al. JOURNAL OF NEUROCHEMISTRY
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