d-serine levels in Alzheimer’s disease: implications for novel biomarker development

The serine shuttle between glia and neurons: implications for neurotransmission and neurodegeneration: Figure 1

(2015) Herman Wolosker et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

LOSS OF FUNCTIONAL CONNECTIVITY IS GREATER OUTSIDE THE DEFAULT MODE NETWORK IN NON-FAMILIAL EARLY-ONSET AD VARIANTS

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Phosphorylated Tau-Aβ 42 Ratio as a Continuous Trait for Biomarker Discovery for Early-Stage Alzheimer’s Disease in Multiplex Immunoassay Panels of Cerebrospinal Fluid

(2014) Oscar Harari et al.   BIOLOGICAL PSYCHIATRY

A Sensitive A  Oligomer Assay Discriminates Alzheimer's and Aged Control Cerebrospinal Fluid

(2014) M. J. Savage et al.   JOURNAL OF NEUROSCIENCE

Translational control of mGluR-dependent long-term depression and object-place learning by eIF2α

(2014) Gonzalo Viana Di Prisco et al.   NATURE NEUROSCIENCE

d-serine prevents cognitive deficits induced by acute stress

(2014) G.D. Guercio et al.   NEUROPHARMACOLOGY

Longitudinal Change in CSF Biomarkers in Autosomal-Dominant Alzheimer's Disease

(2014) A. M. Fagan et al.   Science Translational Medicine

A diagnostic scale for Alzheimer’s disease based on cerebrospinal fluid biomarker profiles

(2014) Sylvain Lehmann et al.   Alzheimers Research & Therapy

Hypocretin and brain β-amyloid peptide interactions in cognitive disorders and narcolepsy

(2014) Yves A. Dauvilliers et al.   Frontiers in Aging Neuroscience

TNF-α Mediates PKR-Dependent Memory Impairment and Brain IRS-1 Inhibition Induced by Alzheimer’s β-Amyloid Oligomers in Mice and Monkeys

(2013) Mychael V. Lourenco et al.   Cell Metabolism

Deregulation of excitatory neurotransmission underlying synapse failure in Alzheimer's disease

(2013) Andrea C. Paula-Lima et al.   JOURNAL OF NEUROCHEMISTRY

Memantine and Cholinesterase Inhibitors: Complementary Mechanisms in the Treatment of Alzheimer’s Disease

(2013) Chris G. Parsons et al.   NEUROTOXICITY RESEARCH

Cerebrospinal Fluid PKR Level Predicts Cognitive Decline in Alzheimer’s Disease

(2013) Julien Dumurgier et al.   PLoS One

A  induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss

(2013) M. Talantova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neurotoxicity of Amyloid  -Protein: Synaptic and Network Dysfunction

(2013) L. Mucke et al.   Cold Spring Harbor Perspectives in Medicine

The Clinical Problem of Symptomatic Alzheimer Disease and Mild Cognitive Impairment

(2013) R. Tarawneh et al.   Cold Spring Harbor Perspectives in Medicine

Contribution of serine racemase/d-serine pathway to neuronal apoptosis

(2012) Simona Esposito et al.   AGING CELL

Serine racemase: an unconventional enzyme for an unconventional transmitter

(2012) Herman Wolosker et al.   AMINO ACIDS

Increased Cerebrospinal Fluid Levels of Double-Stranded RNA-Dependant Protein Kinase in Alzheimer's Disease

(2012) François Mouton-Liger et al.   BIOLOGICAL PSYCHIATRY

Cerebrospinal Fluid Biomarkers in Alzheimer's Disease and Geriatric Depression: Preliminary Findings from Brazil

(2012) Taylor Reis et al.   CNS Neuroscience & Therapeutics

D-Serine

(2012) Inna Radzishevsky et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

The effects of subchronic d-serine on left–right discrimination learning, social interaction, and exploratory activity in APPswe/PS1 mice

(2012) Mohammed Filali et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Astrocyte-induced Synaptogenesis Is Mediated by Transforming Growth Factor β Signaling through Modulation of d-Serine Levels in Cerebral Cortex Neurons

(2012) Luan Pereira Diniz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid-β Oligomers Induce Differential Gene Expression in Adult Human Brain Slices

(2012) Adriano Sebollela et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid-β oligomers link depressive-like behavior and cognitive deficits in mice

(2012) J H Ledo et al.   MOLECULAR PSYCHIATRY

Plasma levels of D-serine in Brazilian individuals with schizophrenia

(2012) Marilia A. Calcia et al.   SCHIZOPHRENIA RESEARCH

Preventing Alzheimer's Disease

(2012) D. J. Selkoe   SCIENCE

Alzheimer CSF biomarkers in routine clinical setting

(2011) F. Tabaraud et al.   ACTA NEUROLOGICA SCANDINAVICA

Introduction to the recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Clifford R. Jack et al.   Alzheimers & Dementia

Revision of the criteria for Alzheimer's disease: A symposium

(2011) Steven T. DeKosky et al.   Alzheimers & Dementia

The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Guy M. McKhann et al.   Alzheimers & Dementia

Aβ Oligomers Induce Glutamate Release from Hippocampal Neurons

(2011) J. Brito-Moreira et al.   Current Alzheimer Research

Changing Concepts of Alzheimer Disease

(2011) Guy M. McKhann   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Soluble A  Oligomers Inhibit Long-Term Potentiation through a Mechanism Involving Excessive Activation of Extrasynaptic NR2B-Containing NMDA Receptors

(2011) S. Li et al.   JOURNAL OF NEUROSCIENCE

The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer’s disease

(2011) Sergio T. Ferreira et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Effects of low-dose d-serine on recognition and working memory in mice

(2011) Patricia Bado et al.   PSYCHOPHARMACOLOGY

Activation of D1/D5 Dopamine Receptors Protects Neurons from Synapse Dysfunction Induced by Amyloid-β Oligomers

(2010) Sofia Jürgensen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

N-Methyl-d-aspartate receptors are required for synaptic targeting of Alzheimer’s toxic amyloid-β peptide oligomers

(2010) Helena Decker et al.   JOURNAL OF NEUROCHEMISTRY

Protein kinase C activity regulates d-serine availability in the brain

(2010) Charles Vargas-Lopes et al.   JOURNAL OF NEUROCHEMISTRY

Serine Racemase Deletion Protects Against Cerebral Ischemia and Excitotoxicity

(2010) A. K. Mustafa et al.   JOURNAL OF NEUROSCIENCE

Cerebrospinal fluid and plasma biomarkers in Alzheimer disease

(2010) Kaj Blennow et al.   Nature Reviews Neurology

Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders

(2010) Giles E. Hardingham et al.   NATURE REVIEWS NEUROSCIENCE

A Specific Enzyme-Linked Immunosorbent Assay for Measuring β-Amyloid Protein Oligomers in Human Plasma and Brain Tissue of Patients With Alzheimer Disease

(2009) Weiming Xia et al.   ARCHIVES OF NEUROLOGY

Phosphodiesterase 5 Inhibition Improves Synaptic Function, Memory, and Amyloid-  Load in an Alzheimer's Disease Mouse Model

(2009) D. Puzzo et al.   JOURNAL OF NEUROSCIENCE

Soluble Oligomers of Amyloid β Protein Facilitate Hippocampal Long-Term Depression by Disrupting Neuronal Glutamate Uptake

(2009) Shaomin Li et al.   NEURON

Reversal of long-term dendritic spine alterations in Alzheimer disease models

(2009) D. L. Smith et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

d-Amino acids in the brain: d-serine in neurotransmission and neurodegeneration

(2008) Herman Wolosker et al.   FEBS Journal

Core candidate neurochemical and imaging biomarkers of Alzheimer’s disease

(2007) Harald Hampel et al.   Alzheimers & Dementia