Alzheimer Aβ peptide interactions with lipid membranes

Conformational dynamics of human IAPP monomers

(2012) Ronan D. Murphy et al.   BIOPHYSICAL CHEMISTRY

Molecular Interactions of Alzheimer's Aβ Protofilaments with Lipid Membranes

(2012) Florentina Tofoleanu et al.   JOURNAL OF MOLECULAR BIOLOGY

The Effect of Aβ on IAPP Aggregation in the Presence of an Isolated β-Cell Membrane

(2012) Janine Seeliger et al.   JOURNAL OF MOLECULAR BIOLOGY

Elongation Kinetics of Polyglutamine Peptide Fibrils: A Quartz Crystal Microbalance with Dissipation Study

(2012) Robert H. Walters et al.   JOURNAL OF MOLECULAR BIOLOGY

Oligomeric Intermediates in Amyloid Formation: Structure Determination and Mechanisms of Toxicity

(2012) Marcus Fändrich   JOURNAL OF MOLECULAR BIOLOGY

Atomic Force Microscopy and MD Simulations Reveal Pore-Like Structures of All-d-Enantiomer of Alzheimer’s β-Amyloid Peptide: Relevance to the Ion Channel Mechanism of AD Pathology

(2012) Laura Connelly et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Atomic View of a Toxic Amyloid Small Oligomer

(2012) Arthur Laganowsky et al.   SCIENCE

Evidence from Solid-State NMR for Nonhelical Conformations in the Transmembrane Domain of the Amyloid Precursor Protein

(2011) Jun-Xia Lu et al.   BIOPHYSICAL JOURNAL

Shedding Light on Alzheimer's β-Amyloid Aggregation with Chemical Tools

(2011) Aphrodite Kapurniotu   CHEMBIOCHEM

Lipid matrix plays a role in Abeta fibril kinetics and morphology

(2011) Marc-Antoine Sani et al.   FEBS LETTERS

Are Peptides Good Two-State Folders?

(2011) Alexander M. Berezhkovskii et al.   Journal of Chemical Theory and Computation

Amphiphilic Adsorption of Human Islet Amyloid Polypeptide Aggregates to Lipid/Aqueous Interfaces

(2011) Dequan Xiao et al.   JOURNAL OF MOLECULAR BIOLOGY

Dynamics of protein folding: Probing the kinetic network of folding–unfolding transitions with experiment and theory

(2010) Ginka S. Buchner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

β-Barrel Topology of Alzheimer's β-Amyloid Ion Channels

(2010) Hyunbum Jang et al.   JOURNAL OF MOLECULAR BIOLOGY

Peripherally Applied A -Containing Inoculates Induce Cerebral  -Amyloidosis

(2010) Y. S. Eisele et al.   SCIENCE

Prion-Like Behavior of Amyloid- 

(2010) J. Kim et al.   SCIENCE

Misfolded Amyloid Ion Channels Present Mobile β-Sheet Subunits in Contrast to Conventional Ion Channels

(2009) Hyunbum Jang et al.   BIOPHYSICAL JOURNAL

Transmembrane Structures of Amyloid Precursor Protein Dimer Predicted by Replica-Exchange Molecular Dynamics Simulations

(2009) Naoyuki Miyashita et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structures of β-Amyloid Peptide 1−40, 1−42, and 1−55—the 672−726 Fragment of APP—in a Membrane Environment with Implications for Interactions with γ-Secretase

(2009) Naoyuki Miyashita et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Efficiency of Histidine-Associating Compounds for Blocking the Alzheimer's Aβ Channel Activity and Cytotoxicity

(2008) Nelson Arispe et al.   BIOPHYSICAL JOURNAL

Metal effects on the membrane interactions of amyloid-β peptides

(2008) John D. Gehman et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Annular Protofibrils Are a Structurally and Functionally Distinct Type of Amyloid Oligomer

(2008) Rakez Kayed et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloidogenic Processing but Not Amyloid Precursor Protein (APP) Intracellular C-terminal Domain Production Requires a Precisely Oriented APP Dimer Assembled by Transmembrane GXXXG Motifs

(2008) Pascal Kienlen-Campard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New structures help the modeling of toxic amyloidß ion channels

(2008) Hyunbum Jang et al.   TRENDS IN BIOCHEMICAL SCIENCES