Blockade of EphA4 signaling ameliorates hippocampal synaptic dysfunctions in mouse models of Alzheimer’s disease

Early Changes in Hippocampal Eph Receptors Precede the Onset of Memory Decline in Mouse Models of Alzheimer's Disease

(2017) Ana María Simón et al.   JOURNAL OF ALZHEIMERS DISEASE

Melanocortin-4 Receptor Regulates Hippocampal Synaptic Plasticity through a Protein Kinase A-Dependent Mechanism

(2013) Y. Shen et al.   JOURNAL OF NEUROSCIENCE

Neurotoxicity of Amyloid  -Protein: Synaptic and Network Dysfunction

(2013) L. Mucke et al.   Cold Spring Harbor Perspectives in Medicine

Distinctive binding of three antagonistic peptides to the ephrin-binding pocket of the EphA4 receptor

(2012) Ilaria Lamberto et al.   BIOCHEMICAL JOURNAL

Alzheimer Mechanisms and Therapeutic Strategies

(2012) Yadong Huang et al.   CELL

Synapses and Alzheimer's Disease

(2012) M. Sheng et al.   Cold Spring Harbor Perspectives in Biology

A Comprehensive Genetic Association Study of Alzheimer Disease in African Americans

(2011) Mark W. Logue   ARCHIVES OF NEUROLOGY

Isoliquiritigenin is a Novel NMDA Receptor Antagonist in Kampo Medicine Yokukansan

(2011) Zenji Kawakami et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Eph receptors at synapses: Implications in neurodegenerative diseases

(2011) Yu Chen et al.   CELLULAR SIGNALLING

A Disalicylic Acid-Furanyl Derivative Inhibits Ephrin Binding to a Subset of Eph Receptors

(2011) Roberta Noberini et al.   Chemical Biology & Drug Design

Eph receptors and ephrins in neuron-astrocyte communication at synapses

(2011) Keith K. Murai et al.   GLIA

Crystal structure of the ligand-binding domain of the promiscuous EphA4 receptor reveals two distinct conformations

(2010) Nikhil Singla et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Antihypertensive and neuroprotective activities of rhynchophylline: The role of rhynchophylline in neurotransmission and ion channel activity

(2010) Jiyin Zhou et al.   JOURNAL OF ETHNOPHARMACOLOGY

EphA4 is localized in clathrin-coated and synaptic vesicles in adult mouse brain

(2010) David Bouvier et al.   JOURNAL OF NEUROCHEMISTRY

Reversing EphB2 depletion rescues cognitive functions in Alzheimer model

(2010) Moustapha Cissé et al.   NATURE

APCCdh1 mediates EphA4-dependent downregulation of AMPA receptors in homeostatic plasticity

(2010) Amy K Y Fu et al.   NATURE NEUROSCIENCE

Whole genome association study of brain-wide imaging phenotypes for identifying quantitative trait loci in MCI and AD: A study of the ADNI cohort

(2010) Li Shen et al.   NEUROIMAGE

Structural Characterization of the EphA4-Ephrin-B2 Complex Reveals New Features Enabling Eph-Ephrin Binding Promiscuity

(2009) Haina Qin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuron-glia communication via EphA4/ephrin-A3 modulates LTP through glial glutamate transport

(2009) Alessandro Filosa et al.   NATURE NEUROSCIENCE

Soluble Oligomers of Amyloid β Protein Facilitate Hippocampal Long-Term Depression by Disrupting Neuronal Glutamate Uptake

(2009) Shaomin Li et al.   NEURON

Bidirectional signaling of ErbB and Eph receptors at synapses

(2009) Yu Chen et al.   Neuron Glia Biology

Oligomeric amyloid   associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques

(2009) R. M. Koffie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Plasticity of Eph Receptor A4 Facilitates Cross-Class Ephrin Signaling

(2009) Thomas A. Bowden et al.   STRUCTURE

Eph-Ephrin Bidirectional Signaling in Physiology and Disease

(2008) Elena B. Pasquale   CELL

Crystal Structure and NMR Binding Reveal That Two Small Molecule Antagonists Target the High Affinity Ephrin-binding Channel of the EphA4 Receptor

(2008) Haina Qin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Small Molecules Can Selectively Inhibit Ephrin Binding to the EphA4 and EphA2 Receptors

(2008) Roberta Noberini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

(2008) Ganesh M Shankar et al.   NATURE MEDICINE

Bidirectional modulation of synaptic functions by Eph/ephrin signaling

(2008) Rüdiger Klein   NATURE NEUROSCIENCE

Vaccination with soluble Aβ oligomers generates toxicity-neutralizing antibodies

(2003) Mary P. Lambert et al.   JOURNAL OF NEUROCHEMISTRY