Endocannabinoids: A Promising Impact for Traumatic Brain Injury

Natural Cannabinoids Improve Dopamine Neurotransmission and Tau and Amyloid Pathology in a Mouse Model of Tauopathy

(2018) Maria J. Casarejos et al.   JOURNAL OF ALZHEIMERS DISEASE

Neuropsychiatric Symptom Modeling in Male and Female C57BL/6J Mice after Experimental Traumatic Brain Injury

(2017) Laura B. Tucker et al.   JOURNAL OF NEUROTRAUMA

Inhibition of Endocannabinoid Degradation Improves Outcomes from Mild Traumatic Brain Injury: A Mechanistic Role for Synaptic Hyperexcitability

(2017) Jacques Mayeux et al.   JOURNAL OF NEUROTRAUMA

CB1 receptor antagonism prevents long-term hyperexcitability after head injury by regulation of dynorphin-KOR system and mGluR5 in rat hippocampus

(2016) Xiu Wang et al.   BRAIN RESEARCH

Endocannabinoid regulation of nausea is mediated by 2-arachidonoylglycerol (2-AG) in the rat visceral insular cortex

(2016) Martin A. Sticht et al.   NEUROPHARMACOLOGY

Chronic Posttraumatic Epilepsy following Neocortical Undercut Lesion in Mice

(2016) Xingjie Ping et al.   PLoS One

Endocannabinoids modulate human blood-brain barrier permeabilityin vitro

(2015) William H Hind et al.   BRITISH JOURNAL OF PHARMACOLOGY

Inhibition of Monoacylglycerol Lipase Prevents Chronic Traumatic Encephalopathy-like Neuropathology in a Mouse Model of Repetitive Mild Closed Head Injury

(2015) Jian Zhang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Human lung-resident macrophages express CB1 and CB2 receptors whose activation inhibits the release of angiogenic and lymphangiogenic factors

(2015) Rosaria I. Staiano et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Endocannabinoid Degradation Inhibition Improves Neurobehavioral Function, Blood–Brain Barrier Integrity, and Neuroinflammation following Mild Traumatic Brain Injury

(2015) Paige S. Katz et al.   JOURNAL OF NEUROTRAUMA

Pathophysiology and Neuroprotection of Global and Focal Perinatal Brain Injury: Lessons From Animal Models

(2015) Luigi Titomanlio et al.   PEDIATRIC NEUROLOGY

The fatty acid amide hydrolase inhibitor PF-3845 promotes neuronal survival, attenuates inflammation and improves functional recovery in mice with traumatic brain injury

(2014) Flaubert Tchantchou et al.   NEUROPHARMACOLOGY

Voltage-gated sodium (NaV) channel blockade by plant cannabinoids does not confer anticonvulsant effects per se

(2014) Andrew J. Hill et al.   NEUROSCIENCE LETTERS

Synthetic cannabinoids

(2013) T. Antoniou et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

Neuroprotection and reduction of glial reaction by cannabidiol treatment after sciatic nerve transection in neonatal rats

(2013) Matheus Perez et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Does the Neuroprotective Role of Anandamide Display Diurnal Variations?

(2013) Marina Martinez-Vargas et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Moving around the molecule: Relationship between chemical structure and in vivo activity of synthetic cannabinoids

(2013) Jenny L. Wiley et al.   LIFE SCIENCES

Monoacylglycerol Lipase (MAGL) Inhibition Attenuates Acute Lung Injury in Mice

(2013) Carolina Costola-de-Souza et al.   PLoS One

The Role of Markers of Inflammation in Traumatic Brain Injury

(2013) Thomas Woodcock et al.   Frontiers in Neurology

The Endocannabinoid System and the Brain

(2012) Raphael Mechoulam et al.   Annual Review of Psychology

Diffusion tensor imaging and volumetric analysis of the ventral striatum in adults with traumatic brain injury

(2012) Sanjeev Shah et al.   BRAIN INJURY

A cannabinoid type 2 receptor agonist attenuates blood-brain barrier damage and neurodegeneration in a murine model of traumatic brain injury

(2012) Peter S. Amenta et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Selective Inhibition of Alpha/Beta-Hydrolase Domain 6 Attenuates Neurodegeneration, Alleviates Blood Brain Barrier Breakdown, and Improves Functional Recovery in a Mouse Model of Traumatic Brain Injury

(2012) Flaubert Tchantchou et al.   JOURNAL OF NEUROTRAUMA

Late mortality after severe traumatic brain injury in New South Wales: a multicentre study

(2012) Ian J Baguley et al.   MEDICAL JOURNAL OF AUSTRALIA

Chronic Traumatic Encephalopathy in Blast-Exposed Military Veterans and a Blast Neurotrauma Mouse Model

(2012) L. E. Goldstein et al.   Science Translational Medicine

O-Hydroxyacetamide Carbamates as a Highly Potent and Selective Class of Endocannabinoid Hydrolase Inhibitors

(2011) Micah J. Niphakis et al.   ACS Chemical Neuroscience

Similarities and differences in spatial learning and object recognition between young male C57Bl/6J mice and Sprague-Dawley rats.

(2011) Alexis M. Stranahan   BEHAVIORAL NEUROSCIENCE

Pre- and post-conditioning treatment with an ultra-low dose of Δ9-tetrahydrocannabinol (THC) protects against pentylenetetrazole (PTZ)-induced cognitive damage

(2011) Fadi Assaf et al.   BEHAVIOURAL BRAIN RESEARCH

Estradiol Decreases Cortical Reactive Astrogliosis after Brain Injury by a Mechanism Involving Cannabinoid Receptors

(2011) A. B. Lopez Rodriguez et al.   CEREBRAL CORTEX

A mouse model of blast-induced mild traumatic brain injury

(2011) Vardit Rubovitch et al.   EXPERIMENTAL NEUROLOGY

Cannabidiol-treated Rats Exhibited Higher Motor Score After Cryogenic Spinal Cord Injury

(2011) Marcelo Kwiatkoski et al.   NEUROTOXICITY RESEARCH

The major central endocannabinoid directly acts at GABAA receptors

(2011) E. Sigel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Supply and demand for endocannabinoids

(2011) Bradley E. Alger et al.   TRENDS IN NEUROSCIENCES

Blood–Brain Barrier Pathophysiology in Traumatic Brain Injury

(2011) Adam Chodobski et al.   Translational Stroke Research

Acute management of acquired brain injury part II: An evidence-based review of pharmacological interventions

(2010) Matthew J. Meyer et al.   BRAIN INJURY

Phytocannabinoids beyond the Cannabis plant - do they exist?

(2010) J������rg Gertsch et al.   BRITISH JOURNAL OF PHARMACOLOGY

CB1cannabinoid receptors promote oxidative/nitrosative stress, inflammation and cell death in a murine nephropathy model

(2010) Partha Mukhopadhyay et al.   BRITISH JOURNAL OF PHARMACOLOGY

CB2: a cannabinoid receptor with an identity crisis

(2010) Brady K Atwood et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Epidemiology of Traumatic Brain Injury

(2010) John D. Corrigan et al.   JOURNAL OF HEAD TRAUMA REHABILITATION

150 Years of Treating Severe Traumatic Brain Injury: A Systematic Review of Progress in Mortality

(2010) Sherman C. Stein et al.   JOURNAL OF NEUROTRAUMA

Traumatic brain injury and amyloid-β pathology: a link to Alzheimer's disease?

(2010) Victoria E. Johnson et al.   NATURE REVIEWS NEUROSCIENCE

Acute Lung Injury Is an Independent Risk Factor for Brain Hypoxia After Severe Traumatic Brain Injury

(2010) Mauro Oddo et al.   NEUROSURGERY

Use of magnesium in traumatic brain injury

(2010) Ananda P. Sen et al.   Neurotherapeutics

CB1 cannabinoid receptors promote oxidative stress and cell death in murine models of doxorubicin-induced cardiomyopathy and in human cardiomyocytes

(2009) Partha Mukhopadhyay et al.   CARDIOVASCULAR RESEARCH

Discovery and Characterization of a Highly Selective FAAH Inhibitor that Reduces Inflammatory Pain

(2009) Kay Ahn et al.   CHEMISTRY & BIOLOGY

Thematic Review Series: Proteomics.An integrated omics analysis of eicosanoid biology,

(2009) Matthew W. Buczynski et al.   JOURNAL OF LIPID RESEARCH

Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord

(2009) K. A. Kigerl et al.   JOURNAL OF NEUROSCIENCE

Safety and Tolerability of Cyclosporin A in Severe Traumatic Brain Injury Patients: Results from a Prospective Randomized Trial

(2009) Anna Teresa Mazzeo et al.   JOURNAL OF NEUROTRAUMA

Detection of behavioral alterations and learning deficits in mice lacking synaptophysin

(2009) U. Schmitt et al.   NEUROSCIENCE

Complications of decompressive craniectomy for traumatic brain injury

(2009) Shirley I. Stiver   Neurosurgical Focus

Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo

(2009) J. Z. Long et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pretreatment With Electroacupuncture Induces Rapid Tolerance to Focal Cerebral Ischemia Through Regulation of Endocannabinoid System

(2009) Qiang Wang et al.   STROKE

Extent of Microstructural White Matter Injury in Postconcussive Syndrome Correlates with Impaired Cognitive Reaction Time: A 3T Diffusion Tensor Imaging Study of Mild Traumatic Brain Injury

(2008) S.N. Niogi et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Monoacylglycerol lipase regulates 2-arachidonoylglycerol action and arachidonic acid levels

(2008) Daniel K. Nomura et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Comparative Neuroprotective Effects of Cyclosporin a and NIM811, a Nonimmunosuppressive Cyclosporin a Analog, following Traumatic Brain Injury

(2008) Lamin Han Mbye et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Effect of Rosuvastatin on Amnesia and Disorientation after Traumatic Brain Injury (NCT00329758)

(2008) J. Humberto Tapia-Perez et al.   JOURNAL OF NEUROTRAUMA

Targeting the endocannabinoid system: to enhance or reduce?

(2008) Vincenzo Di Marzo   NATURE REVIEWS DRUG DISCOVERY

The endogenous fatty acid amide, palmitoylethanolamide, has anti-allodynic and anti-hyperalgesic effects in a murine model of neuropathic pain: involvement of CB1, TRPV1 and PPARγ receptors and neurotrophic factors

(2008) Barbara Costa et al.   PAIN

2-Arachidonoylglycerol, an endogenous cannabinoid receptor agonist, in various rat tissues during the evolution of experimental cholestatic liver disease

(2008) Yosefa Avraham et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

CB2receptors in the brain: role in central immune function

(2007) G A Cabral et al.   BRITISH JOURNAL OF PHARMACOLOGY

The orphan receptor GPR55 is a novel cannabinoid receptor

(2007) E Ryberg et al.   BRITISH JOURNAL OF PHARMACOLOGY