Review
Behavioral Sciences
Alex Medina Escobar, Tamara Pringsheim, Zahra Goodarzi, Davide Martino
Summary: Adult onset idiopathic dystonia (AOID) patients have a high prevalence of supra-clinical threshold depressive symptoms/depressive disorders, with specific numbers varying among different types of dystonia. The prevalence of supra-clinical threshold depressive symptoms screened by rating scales is higher than that of depressive disorders diagnosed with structured interviews. Further research is needed to standardize screening methodology and characterization of mood disorders in AOID.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2021)
Article
Clinical Neurology
Ching- Hung, Chen-Te Wu, Yi-Ping Chao
Summary: This study compared the differences in gray matter volumes (GMVs) of subcortical nuclei between major depressive disorder (MDD) patients with and without persistent depressive disorder (PDD) at long-term follow-up. The results showed that MDD patients with PDD had smaller GMVs in the right putamen and nucleus accumbens compared to those without PDD. These differences became insignificant at the three-year follow-up.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Clinical Neurology
Raj G. Kumar, Nimali Jayasinghe, Rod L. Walker, Laura E. Gibbons, Melinda C. Power, Eric B. Larson, Paul K. Crane, Kristen Dams-O Connor
Summary: In older males, traumatic brain injury with loss of consciousness (LOC) and past military employment are associated with late-life trajectories of depressive symptom severity. There is no such association in females. Recall bias may affect the retrospective assessment of lifetime history of TBI.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Physiology
Franck Amyot, Cillian E. Lynch, John Ollinger, J. Kent Werner, E. Silverman, Carol Moore, Cora Davis, L. Christine Turtzo, Ramon Diaz-Arrastia, Kimbra Kenney
Summary: This study identified a moderate correlation between headache severity and cerebrovascular reactivity in chronic moderate/severe TBI, suggesting that chronic TCVI may contribute to the pathophysiology of persistent post-traumatic headache.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Psychology, Multidisciplinary
Y. Liang, Lele Chen, Qilong Cao, Wei Lin, Qihao Guo, Yuhai Wang
Summary: This study found that depression significantly affects the cognition and activities of daily living of TBI patients, with patients with depression having a higher risk of cognitive impairment and low activities of daily living compared to those without depression.
CURRENT PSYCHOLOGY
(2021)
Article
Psychology, Clinical
Sydney Timmer-Murillo, Andrew T. Schramm, Timothy J. Geier, Emilie Mcleod, Christine L. Larson, Terri A. deRoon-Cassini
Summary: This longitudinal study found that different facets of emotion dysregulation predict the severity of PTSD symptom clusters and depressive symptoms following traumatic injury. Lack of emotional clarity predicts PTSD symptoms, while difficulty accessing emotion regulation strategies predicts depressive symptoms. Future research should explore whether targeted interventions based on symptom presentations are effective in treating PTSD and depression.
EUROPEAN JOURNAL OF PSYCHOTRAUMATOLOGY
(2023)
Article
Medicine, General & Internal
Cathra Halabi, Lynda Norton, Kevin Norton, Wade S. Smith
Summary: This study evaluated digital headpulse biometrics in 44 sports-related concussions in 101 amateur Australian Rules Football athletes and found new headpulse changes after concussion, suggesting that this objective metric may complement return-to-play protocols.
Article
Nursing
Tyler Bell, Michael Crowe, Thomas Novack, Richard D. D. Davis, Despina Stavrinos
Summary: This study investigated the cognitive and affective correlates of brain fog in traumatic brain injury patients. The results showed that symptomatic mild TBI and moderate-to-severe TBI patients had higher levels of brain fog, which was associated with depressive symptoms and poorer cognitive function.
RESEARCH IN NURSING & HEALTH
(2023)
Article
Clinical Neurology
R. Scott Mackin, Chengshi Jin, Emily Burns, Michelle Kassel, Emma Rhodes, Rachel Nosheny, Miriam Ashford, Tim Banh, Joseph Eichenbaum, Kristen Knight, Rachana Tank, Monica R. Camacho, Juliet Fockler, Diana Truran, John Neuhaus, Michael Weiner
Summary: This study examines the association between major depressive disorder (MDD) and cognitive function in different age groups. It finds that MDD is associated with poorer cognitive performance and greater subjective cognitive difficulties across all age groups. However, the impact of MDD on cognition appears to level off in middle age.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Endocrinology & Metabolism
Devi Jayan, Terri A. deRoon-Cassini, Garrett Sauber, Cecilia J. Hillard, Jacklynn M. Fitzgerald
Summary: The presence of subgroups of trauma survivors defined by post-trauma cortisol levels was supported by a study. Analysis showed that individuals with high post-injury cortisol levels developed only dysphoria symptoms, while those with low cortisol levels and severe PTSD symptoms developed both PTSD and dysphoria.
PSYCHONEUROENDOCRINOLOGY
(2022)
Article
Medicine, General & Internal
Hind A. Beydoun, Catherine Butt, May A. Beydoun, Sharmin Hossain, Shaker M. Eid, Alan B. Zonderman
Summary: This study aimed to evaluate the management of TBI across US healthcare institutions and patient characteristics, focusing on TBI-specific procedures. The top 10 procedure codes among hospitalized adults with TBI were characterized, with variations in prevalence rates, trends, and outcomes based on injury severity. The most frequently reported hospitalization procedure codes among TBI patients aimed at homeostatic stabilization and differed in outcomes according to injury severity.
Article
Medicine, General & Internal
Christian D. Weber, Rolf Lefering, Richard M. Sellei, Klemens Horst, Filippo Migliorini, Frank Hildebrand
Summary: This study aimed to identify characteristics and associated injuries of traumatic hip dislocations (THDs) to identify patients at risk. The study found that THDs are frequently associated with high-energy mechanisms and severe concomitant injuries.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Medicine, General & Internal
Olli Tenovuo, Ramon Diaz-Arrastia, Lee E. Goldstein, David J. Sharp, Joukje van der Naalt, Nathan D. Zasler
Summary: Assessment of TBI severity is currently based on non-specific and unreliable clinical evaluations, leading to difficulties in predicting long-term disability. Current approaches to classifying and assessing TBI severity face numerous challenges, and a new method based on risk classification and multimodal data may offer benefits for both patients and clinical research in the field.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Psychology, Clinical
Amelia J. Hicks, Fiona J. Clay, Amelia C. James, Malcolm Hopwood, Jennie L. Ponsford
Summary: Depression symptoms are common after TBI and have a significant impact on various aspects of individuals' lives. Pharmacotherapy is often used to manage depression post TBI, but there is limited research evidence to guide clinical practice. This umbrella review found that while there is insufficient high-quality evidence to recommend specific drugs, some individuals do respond well to pharmacotherapy. Recommendations for further primary studies, systematic reviews, and prescribing advice are provided.
NEUROPSYCHOLOGY REVIEW
(2023)
Article
Pharmacology & Pharmacy
Shih-Te Yang, Hsiu-Yi Hung, Long-Sun Ro, Ming-Feng Liao, Tamara G. Amstislavskaya, Maria A. Tikhonova, Yi-Ling Yang, Kwok-Tung Lu
Summary: Traumatic brain injury (TBI) is a significant cause of mortality and morbidity among young people worldwide, with long-lasting sequelae including paralysis, epilepsy, and mental disorders like major depressive disorder. This study focused on the long-term effects of mild TBI in juvenile animals, revealing that even mild juvenile TBI treatment could lead to sustained adverse effects in adulthood, particularly in terms of depression-like behavior. The chronic administration of the TrkB agonist 7,8-DHF was found to lessen the mTBI-J treatment-induced depression-like behaviors in adult rats, suggesting its potential therapeutic use.
Article
Geriatrics & Gerontology
J. E. Scott, J. L. Mathias, A. C. Kneebone
AGING & MENTAL HEALTH
(2016)
Article
Psychiatry
J. E. Scott, J. L. Mathias, A. C. Kneebone
GENERAL HOSPITAL PSYCHIATRY
(2015)
Review
Behavioral Sciences
Jane L. Mathias, Patricia Wheaton
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2015)
Article
Anesthesiology
Anne L. J. Burke, Linley A. Denson, Jane L. Mathias, Malcolm N. Hogg
Review
Psychology, Developmental
Rachel M. Roberts, Jane L. Mathias, Stephen E. Rose
DEVELOPMENTAL NEUROPSYCHOLOGY
(2016)
Article
Psychology, Clinical
J. E. Scott, J. L. Mathias, A. C. Kneebone, J. Krishnan
JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY
(2017)
Article
Neurosciences
Jhimli Mitra, Kai-kai Shen, Soumya Ghose, Pierrick Bourgeat, Jurgen Fripp, Olivier Salvado, Kerstin Pannek, D. Jamie Taylor, Jane L. Mathias, Stephen Rose
Article
Neurosciences
J. L. Mathias, A. J. Osborn
NEUROPSYCHOLOGICAL REHABILITATION
(2018)
Article
Psychology, Clinical
A. J. Osborn, J. L. Mathias, A. K. Fairweather-Schmidt
Review
Cell & Tissue Engineering
David J. Unsworth, Jane L. Mathias, Diana S. Dorstyn
REGENERATIVE MEDICINE
(2016)
Article
Orthopedics
Julia E. Scott, Jane L. Mathias, Anthony C. Kneebone
JOURNAL OF ARTHROPLASTY
(2014)
Article
Critical Care Medicine
Jane L. Mathias, Yasmin Harman-Smith, Stephen C. Bowden, Jeffrey V. Rosenfeld, Erin D. Bigler
JOURNAL OF NEUROTRAUMA
(2014)
Article
Psychology, Clinical
Susan J. Cockshell, Jane L. Mathias
Proceedings Paper
Engineering, Biomedical
J. Mitra, S. Ghose, P. Bourgeat, J. Fripp, J. L. Mathias, S. Rose, O. Salvado
2016 IEEE 13TH INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING (ISBI)
(2016)
Article
Psychology, Clinical
Anne L. J. Burke, Jane L. Mathias, Linley A. Denson
BRITISH JOURNAL OF CLINICAL PSYCHOLOGY
(2015)
Article
Behavioral Sciences
Edna C. Cieslik, Markus Ullsperger, Martin Gell, Simon B. Eickhoff, Robert Langner
Summary: Previous studies on error processing have primarily focused on the posterior medial frontal cortex, but the role of other brain regions has been underestimated. This study used activation likelihood estimation meta-analyses to explore brain activity related to committing errors and responding successfully in interference tasks. It was found that the salience network and the temporoparietal junction were commonly involved in both correct and incorrect responses, indicating their general involvement in coping with situations that require increased cognitive control. Error-specific convergence was observed in the dorsal posterior cingulate cortex, posterior thalamus, and left superior frontal gyrus, while successful responding showed stronger convergence in the dorsal attention network and lateral prefrontal regions. Underrecruitment of these regions in error trials may reflect failures in activating the appropriate stimulus-response contingencies necessary for successful response execution.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2024)