Flavan-3-ols, anthocyanins, and inflammation

Bioavailability, bioactivity and impact on health of dietary flavonoids and related compounds: an update

(2014) Ana Rodriguez-Mateos et al.   ARCHIVES OF TOXICOLOGY

Epicatechin attenuates atherosclerosis and exerts anti-inflammatory effects on diet-induced human-CRP and NFκB in vivo

(2014) Martine Morrison et al.   ATHEROSCLEROSIS

Anthocyanins from fruit juices improve the antioxidant status of healthy young female volunteers without affecting anti-inflammatory parameters: results from the randomised, double-blind, placebo-controlled, cross-over ANTHONIA (ANTHOcyanins in Nutrition Investigation Alliance) study

(2014) Sabine Kuntz et al.   BRITISH JOURNAL OF NUTRITION

The pharmacokinetics of anthocyanins and their metabolites in humans

(2014) R M de Ferrars et al.   BRITISH JOURNAL OF PHARMACOLOGY

Chemoprevention of Esophageal Cancer with Black Raspberries, Their Component Anthocyanins, and a Major Anthocyanin Metabolite, Protocatechuic Acid

(2014) D. S. Peiffer et al.   Cancer Prevention Research

Evaluation of the Effects ofVaccinium arctostaphylosL. Fruit Extract on Serum Lipids and hs-CRP Levels and Oxidative Stress in Adult Patients with Hyperlipidemia: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

(2014) Rasool Soltani et al.   Evidence-based Complementary and Alternative Medicine

Protocatechuic acid inhibits human dendritic cell functional activation: Role of PPARγ up-modulation

(2014) Manuela Del Cornò et al.   IMMUNOBIOLOGY

Anti-inflammatory effects of anthocyanins-rich extract from bilberry (Vaccinium myrtillusL.) on croton oil-induced ear edema andPropionibacterium acnesplus LPS-induced liver damage in mice

(2014) Hui Luo et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION

Some Anthocyanins Could Be Efficiently Absorbed across the Gastrointestinal Mucosa: Extensive Presystemic Metabolism Reduces Apparent Bioavailability

(2014) Jim Fang   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Berries: Anti-inflammatory Effects in Humans

(2014) Shama V. Joseph et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Immunomodulatory Effect of a Wild Blueberry Anthocyanin-Rich Extract in Human Caco-2 Intestinal Cells

(2014) Valentina Taverniti et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Polyphenol-rich blackcurrant extract prevents inflammation in diet-induced obese mice

(2014) Tyler Benn et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Effect of a Tart Cherry Juice Supplement on Arterial Stiffness and Inflammation in Healthy Adults: A Randomised Controlled Trial

(2014) Anthony Lynn et al.   PLANT FOODS FOR HUMAN NUTRITION

Human studies on the absorption, distribution, metabolism, and excretion of tea polyphenols

(2013) Michael N Clifford et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Human metabolism and elimination of the anthocyanin, cyanidin-3-glucoside: a 13C-tracer study

(2013) Charles Czank et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Malvidin-3-O-β glucoside, major grape anthocyanin, inhibits human macrophage-derived inflammatory mediators and decreases clinical scores in arthritic rats

(2013) Alain Decendit et al.   BIOCHEMICAL PHARMACOLOGY

Assessment of the dietary intake of total flavan-3-ols, monomeric flavan-3-ols, proanthocyanidins and theaflavins in the European Union

(2013) Anna Vogiatzoglou et al.   BRITISH JOURNAL OF NUTRITION

A randomized, double-blind, placebo-controlled trial of the effect of dried purple carrot on body mass, lipids, blood pressure, body composition, and inflammatory markers in overweight and obese adults: The QUENCH Trial

(2013) Olivia R.L. Wright et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

High Anthocyanin Intake Is Associated With a Reduced Risk of Myocardial Infarction in Young and Middle-Aged Women

(2013) Aedín Cassidy et al.   CIRCULATION

Hepatoprotective effect of mulberry water extracts on ethanol-induced liver injury via anti-inflammation and inhibition of lipogenesis in C57BL/6J mice

(2013) Chang-Chieh Tang et al.   FOOD AND CHEMICAL TOXICOLOGY

Distribution and Quantification of Flavan-3-ols and Procyanidins with Low Degree of Polymerization in Nuts, Cereals, and Legumes

(2013) Katharina Bittner et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Intakes of Anthocyanins and Flavones Are Associated with Biomarkers of Insulin Resistance and Inflammation in Women

(2013) Amy Jennings et al.   JOURNAL OF NUTRITION

Wild blueberry (Vaccinium angustifolium) consumption improves inflammatory status in the obese Zucker rat model of the metabolic syndrome

(2013) Stefano Vendrame et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Modulation of metabolic syndrome-related inflammation by cocoa

(2013) Yeyi Gu et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Modulation of Nrf2-dependent gene transcription by bilberry anthocyanins in vivo

(2013) Christopher Kropat et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Edible berries: Bioactive components and their effect on human health

(2013) Shivraj Hariram Nile et al.   NUTRITION

Investigation of the Lipid-Modifying and Antiinflammatory Effects of Cornus mas L. Supplementation on Dyslipidemic Children and Adolescents

(2013) Sedigheh Asgary et al.   PEDIATRIC CARDIOLOGY

Clinical Evaluation of Blood Pressure Lowering, Endothelial Function Improving, Hypolipidemic and Anti-Inflammatory Effects of Pomegranate Juice in Hypertensive Subjects

(2013) Sedigheh Asgary et al.   PHYTOTHERAPY RESEARCH

New insights into the regulation of anthocyanin biosynthesis in fruits

(2013) Laura Jaakola   TRENDS IN PLANT SCIENCE

Dietary flavonoid intakes and risk of type 2 diabetes in US men and women

(2012) Nicole M Wedick et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Flavonoid intake and cardiovascular disease mortality in a prospective cohort of US adults

(2012) Marjorie L McCullough et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Dietary intakes of berries and flavonoids in relation to cognitive decline

(2012) Elizabeth E. Devore et al.   ANNALS OF NEUROLOGY

Dietary (Poly)phenolics in Human Health: Structures, Bioavailability, and Evidence of Protective Effects Against Chronic Diseases

(2012) Daniele Del Rio et al.   ANTIOXIDANTS & REDOX SIGNALING

(−)-Epicatechin prevents TNFα-induced activation of signaling cascades involved in inflammation and insulin sensitivity in 3T3-L1 adipocytes

(2012) Marcela A. Vazquez-Prieto et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Effect of cocoa and green tea on biomarkers of glucose regulation, oxidative stress, inflammation and hemostasis in obese adults at risk for insulin resistance

(2012) K S Stote et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Effect of catechin/epicatechin dietary intake on endothelial dysfunction biomarkers and proinflammatory cytokines in aorta of hyperhomocysteinemic mice

(2012) Christophe Noll et al.   EUROPEAN JOURNAL OF NUTRITION

Effect of a wild blueberry (Vaccinium angustifolium) drink intervention on markers of oxidative stress, inflammation and endothelial function in humans with cardiovascular risk factors

(2012) Patrizia Riso et al.   EUROPEAN JOURNAL OF NUTRITION

Potential anti-inflammatory, anti-adhesive, anti/estrogenic, and angiotensin-converting enzyme inhibitory activities of anthocyanins and their gut metabolites

(2012) Maria Hidalgo et al.   Genes and Nutrition

Effects of anthocyanins on cardiovascular risk factors and inflammation in pre-hypertensive men: a double-blind randomized placebo-controlled crossover study

(2012) S S Hassellund et al.   JOURNAL OF HUMAN HYPERTENSION

Improvement of lipopolysaccharide-induced hepatic injuries and inflammation with mulberry extracts

(2012) Ting-Tsz Ou et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Bilberries reduce low-grade inflammation in individuals with features of metabolic syndrome

(2012) Marjukka Kolehmainen et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Anti-inflammatory effect of purified dietary anthocyanin in adults with hypercholesterolemia: A randomized controlled trial

(2012) Y. Zhu et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Dietary flavan-3-ols intake and metabolic syndrome risk in Korean adults

(2012) Yoon Jung Yang et al.   Nutrition Research and Practice

Cyanidin 3-O-β-d-glucoside-rich blackberries modulate hepatic gene expression, and anti-obesity effects in ovariectomized rats

(2012) Lydia Kaume et al.   Journal of Functional Foods

Effects of cranberry juice consumption on vascular function in patients with coronary artery disease

(2011) Mustali M Dohadwala et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Efficacy of Biological Therapies in Inflammatory Bowel Disease: Systematic Review and Meta-Analysis

(2011) Alexander C Ford et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Inflammatory Mechanisms in Obesity

(2011) Margaret F. Gregor et al.   Annual Review of Immunology

Cyanidin-3-O-β-glucoside with the aid of its metabolite protocatechuic acid, reduces monocyte infiltration in apolipoprotein E-deficient mice

(2011) Dongliang Wang et al.   BIOCHEMICAL PHARMACOLOGY

Intake estimation of total and individual flavan-3-ols, proanthocyanidins and theaflavins, their food sources and determinants in the European Prospective Investigation into Cancer and Nutrition (EPIC) study

(2011) Viktoria Knaze et al.   BRITISH JOURNAL OF NUTRITION

Biomarkers for the Prediction of Type 2 Diabetes and Cardiovascular Disease

(2011) C Herder et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Mechanisms of IgE Inflammation

(2011) Lanny J. Rosenwasser   CURRENT ALLERGY AND ASTHMA REPORTS

Dietary flavonoids: Role of (−)-epicatechin and related procyanidins in cell signaling

(2011) Cesar G. Fraga et al.   FREE RADICAL BIOLOGY AND MEDICINE

The anthocyanin cyanidin-3-O-β-glucoside, a flavonoid, increases hepatic glutathione synthesis and protects hepatocytes against reactive oxygen species during hyperglycemia: Involvement of a cAMP–PKA-dependent signaling pathway

(2011) Wei Zhu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inhibition of Ulcerative Colitis in Mice after Oral Administration of a Polyphenol-Enriched Cocoa Extract Is Mediated by the Inhibition of STAT1 and STAT3 Phosphorylation in Colon Cells

(2011) Isabel Andújar et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Atherosclerosis: current pathogenesis and therapeutic options

(2011) Christian Weber et al.   NATURE MEDICINE

Habitual intake of flavonoid subclasses and incident hypertension in adults

(2010) Aedín Cassidy et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Specific Dietary Polyphenols Attenuate Atherosclerosis in Apolipoprotein E–Knockout Mice by Alleviating Inflammation and Endothelial Dysfunction

(2010) Wai Mun Loke et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

2010 ACCF/AHA Guideline for Assessment of Cardiovascular Risk in Asymptomatic Adults

(2010) et al.   CIRCULATION

Advanced Age Is an Independent Risk Factor for Severe Infections and Mortality in Patients Given Anti–Tumor Necrosis Factor Therapy for Inflammatory Bowel Disease

(2010) Mario Cottone et al.   Clinical Gastroenterology and Hepatology

Saturated Fatty Acids and Risk of Coronary Heart Disease: Modulation by Replacement Nutrients

(2010) Patty W. Siri-Tarino et al.   Current Atherosclerosis Reports

Bilberry juice modulates plasma concentration of NF-κB related inflammatory markers in subjects at increased risk of CVD

(2010) Anette Karlsen et al.   EUROPEAN JOURNAL OF NUTRITION

Flavanols and Anthocyanins in Cardiovascular Health: A Review of Current Evidence

(2010) Sonia De Pascual-Teresa et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Blueberries Decrease Cardiovascular Risk Factors in Obese Men and Women with Metabolic Syndrome

(2010) Arpita Basu et al.   JOURNAL OF NUTRITION

Bioactives in Blueberries Improve Insulin Sensitivity in Obese, Insulin-Resistant Men and Women

(2010) April J. Stull et al.   JOURNAL OF NUTRITION

Cancer risk with tumor necrosis factor alpha (TNF) inhibitors: meta-analysis of randomized controlled trials of adalimumab, etanercept, and infliximab using patient level data

(2010) Johan Askling et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Epicatechin protects the auditory organ by attenuating cisplatin-induced ototoxicity through inhibition of ERK

(2010) J.S. Lee et al.   TOXICOLOGY LETTERS

Insights into the metabolism and microbial biotransformation of dietary flavan-3-ols and the bioactivity of their metabolites

(2010) Maria Monagas et al.   Food & Function

Effect of cocoa powder on the modulation of inflammatory biomarkers in patients at high risk of cardiovascular disease

(2009) Maria Monagas et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Pathogenetic role of hypercholesterolemia in a novel preclinical model of vascular injury in pigs

(2009) Marco Busnelli et al.   ATHEROSCLEROSIS

Dimeric procyanidins are inhibitors of NF-κB–DNA binding

(2009) Gerardo G. Mackenzie et al.   BIOCHEMICAL PHARMACOLOGY

Targeting extracellular signal-regulated kinase (ERK) signaling has therapeutic implications for inflammatory osteolysis

(2009) Sung Wook Seo et al.   BONE

Epicatechin induces NF-κB, activator protein-1 (AP-1) and nuclear transcription factor erythroid 2p45-related factor-2 (Nrf2) via phosphatidylinositol-3-kinase/protein kinase B (PI3K/AKT) and extracellular regulated kinase (ERK) signalling in HepG2 cells

(2009) Ana Belén Granado-Serrano et al.   BRITISH JOURNAL OF NUTRITION

Dietary antioxidant capacity and concentration of adiponectin in apparently healthy adults: the ATTICA study

(2009) P Detopoulou et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Chemical composition andin vitroanti-inflammatory activity of apple phenolic extracts and of their sub-fractions

(2009) Denis R. Lauren et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION

Fruit and Vegetable Consumption and Its Relation to Markers of Inflammation and Oxidative Stress in Adolescents

(2009) Erica M. Holt et al.   JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION

Dietary phenolics: chemistry, bioavailability and effects on health

(2009) Alan Crozier et al.   NATURAL PRODUCT REPORTS

Lipid Rafts and Caveolae and Their Role in Compartmentation of Redox Signaling

(2008) Hemal H. Patel et al.   ANTIOXIDANTS & REDOX SIGNALING

The impact of the 67kDa laminin receptor on both cell-surface binding and anti-allergic action of tea catechins

(2008) Yoshinori Fujimura et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

TNFα-induced NF-κB activation and cell oxidant production are modulated by hexameric procyanidins in Caco-2 cells

(2008) Alejandra G. Erlejman et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Dimeric procyanidin B2 inhibits constitutively active NF-κB in Hodgkin's lymphoma cells independently of the presence of IκB mutations

(2008) Gerardo G. Mackenzie et al.   BIOCHEMICAL PHARMACOLOGY

EGCG reducing the susceptibility to cholesterol gallstone formation through the regulation of inflammation

(2008) Dongmei Shan et al.   BIOMEDICINE & PHARMACOTHERAPY

Adipose tissue dysfunction in obesity, diabetes, and vascular diseases

(2008) G. R. Hajer et al.   EUROPEAN HEART JOURNAL

Dietary flavonoid intake and risk of cancer in postmenopausal women: The Iowa Women's Health Study

(2008) Gretchen J. Cutler et al.   INTERNATIONAL JOURNAL OF CANCER

Bioavailability of Pelargonidin-3-O-glucoside and Its Metabolites in Humans Following the Ingestion of Strawberries with and without Cream

(2008) William Mullen et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Grape-seed procyanidins prevent low-grade inflammation by modulating cytokine expression in rats fed a high-fat diet

(2008) Ximena Terra et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Oligomeric procyanidins inhibit cell migration and modulate the expression of migration and proliferation associated genes in human umbilical vascular endothelial cells

(2008) María-Teresa García-Conesa et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Flavan-3-ols: Nature, occurrence and biological activity

(2007) Patricia M. Aron et al.   MOLECULAR NUTRITION & FOOD RESEARCH