标题
Epigenetic modulation of antitumor immunity for improved cancer immunotherapy
作者
关键词
-
出版物
Molecular Cancer
Volume 20, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2021-12-20
DOI
10.1186/s12943-021-01464-x
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Epigenetics and beyond: targeting writers of protein lysine methylation to treat disease
- (2021) Kamakoti P. Bhat et al. NATURE REVIEWS DRUG DISCOVERY
- Targeting epigenetic regulatory machinery to overcome cancer therapy resistance
- (2021) Lei Guo et al. SEMINARS IN CANCER BIOLOGY
- Low-dose decitabine priming endows CAR T cells with enhanced and persistent antitumour potential via epigenetic reprogramming
- (2021) Yao Wang et al. Nature Communications
- TET-Mediated Epigenetic Regulation in Immune Cell Development and Disease
- (2021) Nikolas James Tsiouplis et al. Frontiers in Cell and Developmental Biology
- Epigenetic Remodeling in Innate Immunity and Inflammation
- (2021) Qian Zhang et al. Annual Review of Immunology
- Clinical advances in targeting epigenetics for cancer therapy
- (2021) Shengrui Feng et al. FEBS Journal
- A gene–environment-induced epigenetic program initiates tumorigenesis
- (2021) Direna Alonso-Curbelo et al. NATURE
- HDAC inhibition potentiates anti-tumor activity of macrophages and enhances anti-PD-L1-mediated tumor suppression
- (2021) Xiaolei Li et al. ONCOGENE
- Super-enhancers: a new frontier for epigenetic modifiers in cancer chemoresistance
- (2021) Guo-Hua Li et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Epigenetic reprogramming of tumor cell–intrinsic STING function sculpts antigenicity and T cell recognition of melanoma
- (2021) Rana Falahat et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Epigenetic mechanisms in breast cancer therapy and resistance
- (2021) Liliana Garcia-Martinez et al. Nature Communications
- Role of Epigenetic Regulation in Plasticity of Tumor Immune Microenvironment
- (2021) Yunkai Yang et al. Frontiers in Immunology
- Fundamentals of T Cell Metabolism and Strategies to Enhance Cancer Immunotherapy
- (2021) Guillermo O. Rangel Rivera et al. Frontiers in Immunology
- STINGing the Tumor Microenvironment to Promote Therapeutic Tertiary Lymphoid Structure Development
- (2021) Jessica N. Filderman et al. Frontiers in Immunology
- TARGETING THE T-CELL LYMPHOMA EPIGENOME INDUCES CELL DEATH, CANCER TESTES ANTIGENS, IMMUNE MODULATORY SIGNALING PATHWAYS.
- (2021) Luigi Scotto et al. MOLECULAR CANCER THERAPEUTICS
- Navigating the DNA methylation landscape of cancer
- (2021) Atsuya Nishiyama et al. TRENDS IN GENETICS
- EGFR-HIF1α signaling positively regulates the differentiation of IL-9 producing T helper cells
- (2021) Suyasha Roy et al. Nature Communications
- Type 17 immunity promotes the exhaustion of CD8+ T cells in cancer
- (2021) Byung-Seok Kim et al. Journal for ImmunoTherapy of Cancer
- The Fate of Th17 Cells is Shaped by Epigenetic Modifications and Remodeled by the Tumor Microenvironment
- (2020) Elodie Renaude et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Role of HDACs in normal and malignant hematopoiesis
- (2020) Pan Wang et al. Molecular Cancer
- Lactate dehydrogenase inhibition synergizes with IL-21 to promote CD8+ T cell stemness and antitumor immunity
- (2020) Dalton Hermans et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- HDAC10 deletion promotes Foxp3+ T-regulatory cell function
- (2020) Satinder Dahiya et al. Scientific Reports
- Histone deacetylase inhibitors valproic acid and vorinostat enhance trastuzumab-mediated antibody-dependent cell-mediated phagocytosis
- (2020) Johannes Laengle et al. Journal for ImmunoTherapy of Cancer
- Myeloid-Derived Suppressor Cells as a Therapeutic Target for Cancer
- (2020) Andrew M. K. Law et al. Cells
- In Vivo CD4+ T Cell Differentiation and Function: Revisiting the Th1/Th2 Paradigm
- (2020) Mikel Ruterbusch et al. Annual Review of Immunology
- Hdac3 is an epigenetic inhibitor of the cytotoxicity program in CD8 T cells
- (2020) Rong En Tay et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Vitamin C supports conversion of human γδ T cells into FOXP3-expressing regulatory cells by epigenetic regulation
- (2020) Léonce Kouakanou et al. Scientific Reports
- The Tumor Microenvironment: A Milieu Hindering and Obstructing Antitumor Immune Responses
- (2020) Alireza Labani-Motlagh et al. Frontiers in Immunology
- LAG3(LAG-3,CD223) DNA methylation correlates with LAG3 expression by tumor and immune cells, immune cell infiltration, and overall survival in clear cell renal cell carcinoma
- (2020) Niklas Klümper et al. Journal for ImmunoTherapy of Cancer
- Transcriptional, Epigenetic and Metabolic Programming of Tumor-Associated Macrophages
- (2020) Irina Larionova et al. Cancers
- HDAC6 Plays a Noncanonical Role in the Regulation of Antitumor Immune Responses, Dissemination, and Invasiveness of Breast Cancer
- (2020) Debarati Banik et al. CANCER RESEARCH
- Metabolic signaling in T cells
- (2020) Justin A. Shyer et al. CELL RESEARCH
- Epigenetics in modulating immune functions of stromal and immune cells in the tumor microenvironment
- (2020) Xingyi Pan et al. Cellular & Molecular Immunology
- Towards a more precise therapy in cancer: Exploring epigenetic complexity
- (2020) Fernando P. Cossío et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Histone H3.3 phosphorylation amplifies stimulation-induced transcription
- (2020) Anja Armache et al. NATURE
- Epigenetic Therapies for Cancer
- (2020) Susan E. Bates NEW ENGLAND JOURNAL OF MEDICINE
- Direct readout of heterochromatic H3K9me3 regulates DNMT1-mediated maintenance DNA methylation
- (2020) Wendan Ren et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Contribution of Epigenetics to Cancer Immunotherapy
- (2020) Lorea Villanueva et al. TRENDS IN IMMUNOLOGY
- Rewriting History: Epigenetic Reprogramming of CD8+ T Cell Differentiation to Enhance Immunotherapy
- (2020) Caitlin C. Zebley et al. TRENDS IN IMMUNOLOGY
- Role of Epigenetic Modifications in Inhibitory Immune Checkpoints in Cancer Development and Progression
- (2020) Reem Saleh et al. Frontiers in Immunology
- Understanding the Mechanisms by Which Epigenetic Modifiers Avert Therapy Resistance in Cancer
- (2020) Anthony Quagliano et al. Frontiers in Oncology
- Tazemetostat in advanced epithelioid sarcoma with loss of INI1/SMARCB1: an international, open-label, phase 2 basket study
- (2020) Mrinal Gounder et al. LANCET ONCOLOGY
- Tazemetostat for patients with relapsed or refractory follicular lymphoma: an open-label, single-arm, multicentre, phase 2 trial
- (2020) Franck Morschhauser et al. LANCET ONCOLOGY
- Cancer SLC43A2 alters T cell methionine metabolism and histone methylation
- (2020) Yingjie Bian et al. NATURE
- Targeting the epigenetic regulation of antitumour immunity
- (2020) Simon J. Hogg et al. NATURE REVIEWS DRUG DISCOVERY
- A discrete subset of epigenetically primed human NK cells mediates antigen-specific immune responses
- (2020) Victoria Stary et al. Science Immunology
- The Roles of Histone Deacetylases and Their Inhibitors in Cancer Therapy
- (2020) Guo Li et al. Frontiers in Cell and Developmental Biology
- The Histone Methyltransferase DOT1L Is Essential for Humoral Immune Responses
- (2020) Liam Kealy et al. Cell Reports
- Immunologic correlates of the abscopal effect in a SMARCB1/INI1-negative Poorly Differentiated Chordoma after EZH2 inhibition and radiotherapy
- (2019) Mrinal M. Gounder et al. CLINICAL CANCER RESEARCH
- Epigenetically-modulated FOXM1 suppresses dendritic cell maturation in pancreatic cancer and colon cancer
- (2019) Zhongshi Zhou et al. Molecular Oncology
- Hypoxia induces rapid changes to histone methylation and reprograms chromatin
- (2019) Michael Batie et al. SCIENCE
- HDAC11 regulates type I interferon signaling through defatty-acylation of SHMT2
- (2019) Ji Cao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Gene activation precedes DNA demethylation in response to infection in human dendritic cells
- (2019) Alain Pacis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- BET Inhibition Modifies Melanoma Infiltrating T Cells and Enhances Response to PD-L1 Blockade
- (2019) Neda Nikbakht et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- The Histone Methyltransferase SETDB1 Controls T Helper Cell Lineage Integrity by Repressing Endogenous Retroviruses
- (2019) Véronique Adoue et al. IMMUNITY
- EZH2 inhibitor GSK126 suppresses anti-tumor immunity by driving production of myeloid-derived suppressor cells
- (2019) Shuo Huang et al. CANCER RESEARCH
- The E3 ligase VHL promotes follicular helper T cell differentiation via glycolytic-epigenetic control
- (2019) Yangyang Zhu et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Regulation of Tumor-Associated Myeloid Cell Activity by CBP/EP300 Bromodomain Modulation of H3K27 Acetylation
- (2019) Denise E. de Almeida Nagata et al. Cell Reports
- Phosphorylation of histone H3.3 at serine 31 promotes p300 activity and enhancer acetylation
- (2019) Sara Martire et al. NATURE GENETICS
- Inhibition of a G9a/DNMT network triggers immune-mediated bladder cancer regression
- (2019) Cristina Segovia et al. NATURE MEDICINE
- Loss of TET2 and TET3 in regulatory T cells unleashes effector function
- (2019) Xiaojing Yue et al. Nature Communications
- The histone methyltransferase Setd2 is indispensable for V(D)J recombination
- (2019) Zhongzhong Ji et al. Nature Communications
- Chromatin Architecture as an Essential Determinant of Dendritic Cell Function
- (2019) Giselle M. Boukhaled et al. Frontiers in Immunology
- Targeting EZH2 enhances antigen presentation, antitumor immunity and circumvents anti-PD-1 resistance in head and neck cancers
- (2019) Liye Zhou et al. CLINICAL CANCER RESEARCH
- Chronic stimulation drives human NK cell dysfunction and epigenetic reprograming
- (2019) Aimee Merino et al. JOURNAL OF CLINICAL INVESTIGATION
- Combining epigenetic drugs with other therapies for solid tumours — past lessons and future promise
- (2019) Daphné Morel et al. Nature Reviews Clinical Oncology
- Epigenetic strategies synergize with PD-L1/PD-1 targeted cancer immunotherapies to enhance antitumor responses
- (2019) Xi Chen et al. Acta Pharmaceutica Sinica B
- Epigenetic aging: more than just a clock when it comes to cancer
- (2019) Ming Yu et al. CANCER RESEARCH
- Epigenetic regulation of macrophages: from homeostasis maintenance to host defense
- (2019) Siyuan Chen et al. Cellular & Molecular Immunology
- STING: a master regulator in the cancer-immunity cycle
- (2019) Yuanyuan Zhu et al. Molecular Cancer
- Mechanisms Controlling PD-L1 Expression in Cancer
- (2019) Jong-Ho Cha et al. MOLECULAR CELL
- Methylation of immune synapse genes modulates tumor immunogenicity
- (2019) Anders Berglund et al. JOURNAL OF CLINICAL INVESTIGATION
- The timeline of epigenetic drug discovery: from reality to dreams
- (2019) A. Ganesan et al. Clinical Epigenetics
- LSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade
- (2018) Wanqiang Sheng et al. CELL
- NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control
- (2018) Jan P. Böttcher et al. CELL
- PD-L1 on host cells is essential for PD-L1 blockade–mediated tumor regression
- (2018) Haidong Tang et al. JOURNAL OF CLINICAL INVESTIGATION
- Phosphorylation of EZH2 by AMPK Suppresses PRC2 Methyltransferase Activity and Oncogenic Function
- (2018) Lixin Wan et al. MOLECULAR CELL
- Suppression of STING signaling through epigenetic silencing and missense mutation impedes DNA damage mediated cytokine production
- (2018) Hiroyasu Konno et al. ONCOGENE
- The epigenetic control of stemness in CD8+T cell fate commitment
- (2018) Luigia Pace et al. SCIENCE
- Epigenetic control of macrophage polarization: implications for targeting tumor-associated macrophages
- (2018) Amber E. de Groot et al. Oncotarget
- HDACi Delivery Reprograms Tumor-Infiltrating Myeloid Cells to Eliminate Antigen-Loss Variants
- (2018) Andrew Nguyen et al. Cell Reports
- Targeting EZH2 Reprograms Intratumoral Regulatory T Cells to Enhance Cancer Immunity
- (2018) David Wang et al. Cell Reports
- DNA methylation and repressive H3K9 and H3K27 trimethylation in the promoter regions of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, and PD-L1 genes in human primary breast cancer
- (2018) Varun Sasidharan Nair et al. Clinical Epigenetics
- Dying to Be Noticed: Epigenetic Regulation of Immunogenic Cell Death for Cancer Immunotherapy
- (2018) Brianne Cruickshank et al. Frontiers in Immunology
- Histone Lysine and Genomic Targets of Histone Acetyltransferases in Mammals
- (2018) Anne K. Voss et al. BIOESSAYS
- Ivosidenib: First Global Approval
- (2018) Sohita Dhillon DRUGS
- Modulation of EZH2 expression in T cells improves efficacy of anti–CTLA-4 therapy
- (2018) Sangeeta Goswami et al. JOURNAL OF CLINICAL INVESTIGATION
- Histone deacetylase 6 in cancer
- (2018) Ting Li et al. Journal of Hematology & Oncology
- Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells
- (2018) Joseph A. Fraietta et al. NATURE
- JMJD6 regulates histone H2A.X phosphorylation and promotes autophagy in triple-negative breast cancer cells via a novel tyrosine kinase activity
- (2018) Yan Liu et al. ONCOGENE
- Inhibition of histone lysine-specific demethylase 1 elicits breast tumor immunity and enhances antitumor efficacy of immune checkpoint blockade
- (2018) Ye Qin et al. ONCOGENE
- The hallmarks of successful anticancer immunotherapy
- (2018) Lorenzo Galluzzi et al. Science Translational Medicine
- KDM5 histone demethylases repress immune response via suppression of STING
- (2018) Lizhen Wu et al. PLOS BIOLOGY
- DNA methylation and repressive histones in the promoters of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, PD-L1, and galectin-9 genes in human colorectal cancer
- (2018) Varun Sasidharan Nair et al. Clinical Epigenetics
- The E3 ligase VHL controls alveolar macrophage function via metabolic–epigenetic regulation
- (2018) Wen Zhang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Noncoding regions are the main source of targetable tumor-specific antigens
- (2018) Céline M. Laumont et al. Science Translational Medicine
- Ezh2 programs TFH differentiation by integrating phosphorylation-dependent activation of Bcl6 and polycomb-dependent repression of p19Arf
- (2018) Fengyin Li et al. Nature Communications
- Interleukin 2 modulates thymic-derived regulatory T cell epigenetic landscape
- (2018) Laurent Chorro et al. Nature Communications
- Suppression of STING Associated with LKB1 Loss in KRAS-Driven Lung Cancer
- (2018) Shunsuke Kitajima et al. Cancer Discovery
- Epigenetic and Transcriptional Regulation in the Induction, Maintenance, Heterogeneity, and Recall-Response of Effector and Memory Th2 Cells
- (2018) Atsushi Onodera et al. Frontiers in Immunology
- Metabolic and Epigenetic Coordination of T Cell and Macrophage Immunity
- (2017) Anthony T. Phan et al. IMMUNITY
- Epigenetic Component p66a Modulates Myeloid-Derived Suppressor Cells by Modifying STAT3
- (2017) Jiaxuan Xin et al. JOURNAL OF IMMUNOLOGY
- The Loss of TET2 Promotes CD8+T Cell Memory Differentiation
- (2017) Shannon A. Carty et al. JOURNAL OF IMMUNOLOGY
- Essential role for histone deacetylase 11 (HDAC11) in neutrophil biology
- (2017) Eva Sahakian et al. JOURNAL OF LEUKOCYTE BIOLOGY
- DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats
- (2017) David Brocks et al. NATURE GENETICS
- Marked for death: targeting epigenetic changes in cancer
- (2017) Sophia Xiao Pfister et al. NATURE REVIEWS DRUG DISCOVERY
- The DNA methyltransferase family: a versatile toolkit for epigenetic regulation
- (2017) Frank Lyko NATURE REVIEWS GENETICS
- TET-mediated active DNA demethylation: mechanism, function and beyond
- (2017) Xiaoji Wu et al. NATURE REVIEWS GENETICS
- Epigenetic therapy activates type I interferon signaling in murine ovarian cancer to reduce immunosuppression and tumor burden
- (2017) Meredith L. Stone et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Epigenetic plasticity and the hallmarks of cancer
- (2017) William A. Flavahan et al. SCIENCE
- BET Proteins as Targets for Anticancer Treatment
- (2017) Anastasios Stathis et al. Cancer Discovery
- Promising landscape for regulating macrophage polarization: epigenetic viewpoint
- (2017) Dexi Zhou et al. Oncotarget
- Prostaglandin E2 Leads to the Acquisition of DNMT3A-Dependent Tolerogenic Functions in Human Myeloid-Derived Suppressor Cells
- (2017) Javier Rodríguez-Ubreva et al. Cell Reports
- Epigenetic modifications of the immune-checkpoint genes CTLA4 and PDCD1 in non-small cell lung cancer results in increased expression
- (2017) Sebastian Marwitz et al. Clinical Epigenetics
- Epi-drugs in combination with immunotherapy: a new avenue to improve anticancer efficacy
- (2017) Roberta Mazzone et al. Clinical Epigenetics
- Antitumor Effects of Epidrug/IFNα Combination Driven by Modulated Gene Signatures in Both Colorectal Cancer and Dendritic Cells
- (2017) Alessandra Fragale et al. Cancer Immunology Research
- Depletion of tumor-associated macrophages switches the epigenetic profile of pancreatic cancer infiltrating T cells and restores their anti-tumor phenotype
- (2017) Simone Borgoni et al. OncoImmunology
- Histone/protein deacetylase 11 targeting promotes Foxp3+ Treg function
- (2017) Jianbing Huang et al. Scientific Reports
- Coinhibitory Pathways in Immunotherapy for Cancer
- (2016) Susanne H. Baumeister et al. Annual Review of Immunology
- Histone deacetylase inhibitors deplete myeloid-derived suppressor cells induced by 4T1 mammary tumors in vivo and in vitro
- (2016) Hai-Fang Wang et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Turning tumour cells into antigen presenting cells: The next step to improve cancer immunotherapy?
- (2016) Marie de Charette et al. EUROPEAN JOURNAL OF CANCER
- Role of TET enzymes in DNA methylation, development, and cancer
- (2016) Kasper Dindler Rasmussen et al. GENES & DEVELOPMENT
- Histone Deacetylase SIRT1 Negatively Regulates the Differentiation of Interleukin-9-Producing CD4 + T Cells
- (2016) Yu Wang et al. IMMUNITY
- Control of Foxp3 stability through modulation of TET activity
- (2016) Xiaojing Yue et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Chromatin Kinases Act on Transcription Factors and Histone Tails in Regulation of Inducible Transcription
- (2016) Steven Z. Josefowicz et al. MOLECULAR CELL
- Histone H2A T120 Phosphorylation Promotes Oncogenic Transformation via Upregulation of Cyclin D1
- (2016) Hitoshi Aihara et al. MOLECULAR CELL
- Regulation and function of the cGAS–STING pathway of cytosolic DNA sensing
- (2016) Qi Chen et al. NATURE IMMUNOLOGY
- Epigenetic drug discovery: breaking through the immune barrier
- (2016) David F. Tough et al. NATURE REVIEWS DRUG DISCOVERY
- Epigenetic modulators, modifiers and mediators in cancer aetiology and progression
- (2016) Andrew P. Feinberg et al. NATURE REVIEWS GENETICS
- IFN-α potentiates the direct and immune-mediated antitumor effects of epigenetic drugs on both metastatic and stem cells of colorectal cancer
- (2016) Maria Buoncervello et al. Oncotarget
- H3K4me3 Demethylase Kdm5a Is Required for NK Cell Activation by Associating with p50 to Suppress SOCS1
- (2016) Dezhi Zhao et al. Cell Reports
- HDACs and HDAC Inhibitors in Cancer Development and Therapy
- (2016) Yixuan Li et al. Cold Spring Harbor Perspectives in Medicine
- Histone acetyltransferases: challenges in targeting bi-substrate enzymes
- (2016) Hannah Wapenaar et al. Clinical Epigenetics
- Innate Immune Recognition of Cancer
- (2015) Seng-Ryong Woo et al. Annual Review of Immunology
- Metabolic reprogramming in macrophages and dendritic cells in innate immunity
- (2015) Beth Kelly et al. CELL RESEARCH
- Histone demethylases in chromatin biology and beyond
- (2015) E. Dimitrova et al. EMBO REPORTS
- The Chromatin-Modifying Enzyme Ezh2 Is Critical for the Maintenance of Regulatory T Cell Identity after Activation
- (2015) Michel DuPage et al. IMMUNITY
- Immunity, inflammation, and cancer: an eternal fight between good and evil
- (2015) Shabnam Shalapour et al. JOURNAL OF CLINICAL INVESTIGATION
- Epigenetic Regulation of Inflammatory Cytokines and Associated Genes in Human Malignancies
- (2015) Rehana Yasmin et al. MEDIATORS OF INFLAMMATION
- Histone deacetylase 11: A novel epigenetic regulator of myeloid derived suppressor cell expansion and function
- (2015) Eva Sahakian et al. MOLECULAR IMMUNOLOGY
- TET1 is a tumor suppressor of hematopoietic malignancy
- (2015) Luisa Cimmino et al. NATURE IMMUNOLOGY
- Acute loss of TET function results in aggressive myeloid cancer in mice
- (2015) Jungeun An et al. Nature Communications
- EZH2 is crucial for both differentiation of regulatory T cells and T effector cell expansion
- (2015) Xiang-Ping Yang et al. Scientific Reports
- HDAC Inhibition Upregulates PD-1 Ligands in Melanoma and Augments Immunotherapy with PD-1 Blockade
- (2015) D. M. Woods et al. Cancer Immunology Research
- Post-Translational Modifications of Histones That Influence Nucleosome Dynamics
- (2014) Gregory D. Bowman et al. CHEMICAL REVIEWS
- H3S28 phosphorylation is a hallmark of the transcriptional response to cellular stress
- (2014) Anna Sawicka et al. GENOME RESEARCH
- New and emerging HDAC inhibitors for cancer treatment
- (2014) Alison C. West et al. JOURNAL OF CLINICAL INVESTIGATION
- Histone Acetylation Facilitates Rapid and Robust Memory CD8 T Cell Response through Differential Expression of Effector Molecules (Eomesodermin and Its Targets: Perforin and Granzyme B)
- (2014) Y. Araki et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: Chromatin Remodeling as a Molecular Basis for the Enhanced Functionality of Memory CD8 T Cells
- (2014) J. K. Northrop et al. JOURNAL OF IMMUNOLOGY
- Epigenetic Regulation of Foxp3 Expression in Regulatory T Cells by DNA Methylation
- (2014) G. Lal et al. JOURNAL OF IMMUNOLOGY
- MicroRNA silencing for cancer therapy targeted to the tumour microenvironment
- (2014) Christopher J. Cheng et al. NATURE
- Erasers of Histone Acetylation: The Histone Deacetylase Enzymes
- (2014) E. Seto et al. Cold Spring Harbor Perspectives in Biology
- Consensus guidelines for the detection of immunogenic cell death
- (2014) Oliver Kepp et al. OncoImmunology
- SIRT1 Limits the Function and Fate of Myeloid-Derived Suppressor Cells in Tumors by Orchestrating HIF-1 -Dependent Glycolysis
- (2013) G. Liu et al. CANCER RESEARCH
- Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function
- (2013) Madhusudhanan Sukumar et al. JOURNAL OF CLINICAL INVESTIGATION
- Cutting Edge: Smad2 and Smad4 Regulate TGF- -Mediated Il9 Gene Expression via EZH2 Displacement
- (2013) A. Wang et al. JOURNAL OF IMMUNOLOGY
- Expression of PD-L1, PD-L2, PD-1 and CTLA4 in myelodysplastic syndromes is enhanced by treatment with hypomethylating agents
- (2013) H Yang et al. LEUKEMIA
- TET enzymes, TDG and the dynamics of DNA demethylation
- (2013) Rahul M. Kohli et al. NATURE
- Histone demethylase Lsd1 represses hematopoietic stem and progenitor cell signatures during blood cell maturation
- (2013) Marc A Kerenyi et al. eLife
- Maturation-related histone modifications in the PU.1 promoter regulate Th9-cell development
- (2012) A. Ramming et al. BLOOD
- Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate
- (2012) Patrick S. Ward et al. CANCER CELL
- Dynamic Transformations of Genome-wide Epigenetic Marking and Transcriptional Control Establish T Cell Identity
- (2012) Jingli A. Zhang et al. CELL
- Histone phosphorylation
- (2012) Dorine Rossetto et al. Epigenetics
- Dual Roles of Immune Cells and Their Factors in Cancer Development and Progression
- (2012) Brian F. Zamarron et al. International Journal of Biological Sciences
- Functions of DNA methylation: islands, start sites, gene bodies and beyond
- (2012) Peter A. Jones NATURE REVIEWS GENETICS
- Class I Histone Deacetylase Inhibitor Entinostat Suppresses Regulatory T Cells and Enhances Immunotherapies in Renal and Prostate Cancer Models
- (2012) Li Shen et al. PLoS One
- Class I histone deacetylase inhibition is a novel mechanism to target regulatory T cells in immunotherapy
- (2012) Li Shen et al. OncoImmunology
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Epigenotype switching at the CD14 and CD209 genes during differentiation of human monocytes to dendritic cells
- (2011) Jörn Bullwinkel et al. Epigenetics
- A 5-aza-2'-deoxycytidine/valproate combination induces cytotoxic T-cell response against mesothelioma
- (2011) S. Leclercq et al. EUROPEAN RESPIRATORY JOURNAL
- Impact of the hypomethylating agent 5-azacytidine on dendritic cells function
- (2011) Jihane Frikeche et al. EXPERIMENTAL HEMATOLOGY
- Romidepsin: a novel histone deacetylase inhibitor for cancer
- (2011) Erin M Bertino et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Histone 3 Lysine 9 (H3K9) Methyltransferase Recruitment to the Interleukin-2 (IL-2) Promoter Is a Mechanism of Suppression of IL-2 Transcription by the Transforming Growth Factor-β-Smad Pathway
- (2011) Yu Wakabayashi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- M2 Macrophages Induced by Prostaglandin E2 and IL-6 from Cervical Carcinoma Are Switched to Activated M1 Macrophages by CD4+ Th1 Cells
- (2011) M. Heusinkveld et al. JOURNAL OF IMMUNOLOGY
- Histone deacetylase inhibition facilitates GM-CSF-mediated expansion of myeloid-derived suppressor cells in vitro and in vivo
- (2011) Brian R. Rosborough et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Homeobox gene Rhox5 is regulated by epigenetic mechanisms in cancer and stem cells and promotes cancer growth
- (2011) Qiang Li et al. Molecular Cancer
- Combination Epigenetic Therapy Has Efficacy in Patients with Refractory Advanced Non-Small Cell Lung Cancer
- (2011) R. A. Juergens et al. Cancer Discovery
- Histone deacetylase inhibitors impair innate immune responses to Toll-like receptor agonists and to infection
- (2010) T. Roger et al. BLOOD
- Hypoxia causes epigenetic gene regulation in macrophages by attenuating Jumonji histone demethylase activity
- (2010) Michaela Tausendschön et al. CYTOKINE
- Epigenetics: The epicenter of the hypoxic response
- (2010) Jenny A. Watson et al. Epigenetics
- Discrete Roles of STAT4 and STAT6 Transcription Factors in Tuning Epigenetic Modifications and Transcription during T Helper Cell Differentiation
- (2010) Lai Wei et al. IMMUNITY
- The role of epigenetics in the acquisition and maintenance of effector function in virus-specific CD8 T cells
- (2010) Matthew R. Olson et al. IUBMB LIFE
- SIRT Inhibitors Induce Cell Death and p53 Acetylation through Targeting Both SIRT1 and SIRT2
- (2010) Barrie Peck et al. MOLECULAR CANCER THERAPEUTICS
- Tools and landscapes of epigenetics
- (2010) Alexander Tarakhovsky NATURE IMMUNOLOGY
- Targeting DNA methylation for epigenetic therapy
- (2010) Xiaojing Yang et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- IL-17 and Th17 Cells
- (2009) Thomas Korn et al. Annual Review of Immunology
- Epigenetic mechanisms of regulation of Foxp3 expression
- (2009) G. Lal et al. BLOOD
- Epigenetic Regulation of c-ROS Receptor Tyrosine Kinase Expression in Malignant Gliomas
- (2009) H. J. Jun et al. CANCER RESEARCH
- Genome-wide Analysis of Histone Methylation Reveals Chromatin State-Based Regulation of Gene Transcription and Function of Memory CD8+ T Cells
- (2009) Yasuto Araki et al. IMMUNITY
- Interplay between Chromatin Remodeling and Epigenetic Changes during Lineage-Specific Commitment to Granzyme B Expression
- (2009) T. Juelich et al. JOURNAL OF IMMUNOLOGY
- Regulation of the Histone Demethylase JMJD1A by Hypoxia-Inducible Factor 1 Enhances Hypoxic Gene Expression and Tumor Growth
- (2009) A. J. Krieg et al. MOLECULAR AND CELLULAR BIOLOGY
- Three Epigenetic Drugs Up-Regulate Homeobox Gene Rhox5 in Cancer Cells through Overlapping and Distinct Molecular Mechanisms
- (2009) Q. Li et al. MOLECULAR PHARMACOLOGY
- Immunomodulatory effects of deacetylase inhibitors: therapeutic targeting of FOXP3+ regulatory T cells
- (2009) Liqing Wang et al. NATURE REVIEWS DRUG DISCOVERY
- Jmjd6 Catalyses Lysyl-Hydroxylation of U2AF65, a Protein Associated with RNA Splicing
- (2009) Celia J. Webby et al. SCIENCE
- Hypoxia upregulates the histone demethylase JMJD1A via HIF-1
- (2008) Sven Wellmann et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1α
- (2008) Patrick J. Pollard et al. BIOCHEMICAL JOURNAL
- Epigenetic Enhancement of Antigen Processing and Presentation Promotes Immune Recognition of Tumors
- (2008) A. F. Setiadi et al. CANCER RESEARCH
- Epigenetic alteration of Wnt pathway antagonists in progressive glandular neoplasia of the lung
- (2008) Julien D.F. Licchesi et al. CARCINOGENESIS
- Epi-drugs to fight cancer: From chemistry to cancer treatment, the road ahead
- (2008) Antonello Mai et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Modes of action of the DNA methyltransferase inhibitors azacytidine and decitabine
- (2008) Carlo Stresemann et al. INTERNATIONAL JOURNAL OF CANCER
- The Histone Demethylases JMJD1A and JMJD2B Are Transcriptional Targets of Hypoxia-inducible Factor HIF
- (2008) Sophie Beyer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Synergistic induction of NY-ESO-1 antigen expression by a novel histone deacetylase inhibitor, valproic acid, with 5-aza-2′-deoxycytidine in glioma cells
- (2008) Sachie Oi et al. JOURNAL OF NEURO-ONCOLOGY
- Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9–producing subset
- (2008) Marc Veldhoen et al. NATURE IMMUNOLOGY
- The tumor microenvironment and its role in promoting tumor growth
- (2008) T L Whiteside ONCOGENE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now