标题
Acute loss of TET function results in aggressive myeloid cancer in mice
作者
关键词
-
出版物
Nature Communications
Volume 6, Issue 1, Pages -
出版商
Springer Nature
发表日期
2015-11-26
DOI
10.1038/ncomms10071
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- CRL4VprBP E3 Ligase Promotes Monoubiquitylation and Chromatin Binding of TET Dioxygenases
- (2015) Tadashi Nakagawa et al. MOLECULAR CELL
- Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex
- (2015) Lanfeng Wang et al. NATURE
- Function and information content of DNA methylation
- (2015) Dirk Schübeler NATURE
- Genomic profiling of DNA methyltransferases reveals a role for DNMT3B in genic methylation
- (2015) Tuncay Baubec et al. NATURE
- TET1 is a tumor suppressor of hematopoietic malignancy
- (2015) Luisa Cimmino et al. NATURE IMMUNOLOGY
- Simultaneous deletion of the methylcytosine oxidases Tet1 and Tet3 increases transcriptome variability in early embryogenesis
- (2015) Jinsuk Kang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanism and Function of Oxidative Reversal of DNA and RNA Methylation
- (2014) Li Shen et al. Annual Review of Biochemistry
- Enforced differentiation of Dnmt3a-null bone marrow leads to failure with c-Kit mutations driving leukemic transformation
- (2014) H. Celik et al. BLOOD
- Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation
- (2014) A. Mayle et al. BLOOD
- Reprogramming Committed Murine Blood Cells to Induced Hematopoietic Stem Cells with Defined Factors
- (2014) Jonah Riddell et al. CELL
- Reversing DNA Methylation: Mechanisms, Genomics, and Biological Functions
- (2014) Hao Wu et al. CELL
- TET proteins and 5-methylcytosine oxidation in hematological cancers
- (2014) Myunggon Ko et al. IMMUNOLOGICAL REVIEWS
- 5mC Oxidation by Tet2 Modulates Enhancer Activity and Timing of Transcriptome Reprogramming during Differentiation
- (2014) Gary C. Hon et al. MOLECULAR CELL
- 5-Hydroxymethylcytosine is a predominantly stable DNA modification
- (2014) Martin Bachman et al. Nature Chemistry
- Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells
- (2014) Y. Huang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Notes on the role of dynamic DNA methylation in mammalian development
- (2014) Timothy H. Bestor et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dissecting the dynamic changes of 5-hydroxymethylcytosine in T-cell development and differentiation
- (2014) A. Tsagaratou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Chromatin state dynamics during blood formation
- (2014) D. Lara-Astiaso et al. SCIENCE
- Connections between TET proteins and aberrant DNA modification in cancer
- (2014) Yun Huang et al. TRENDS IN GENETICS
- A targeted mutational landscape of angioimmunoblastic T-cell lymphoma
- (2013) O. Odejide et al. BLOOD
- Dynamic Readers for 5-(Hydroxy)Methylcytosine and Its Oxidized Derivatives
- (2013) Cornelia G. Spruijt et al. CELL
- MicroRNA-Antagonism Regulates Breast Cancer Stemness and Metastasis via TET-Family-Dependent Chromatin Remodeling
- (2013) Su Jung Song et al. CELL
- The Oncogenic MicroRNA miR-22 Targets the TET2 Tumor Suppressor to Promote Hematopoietic Stem Cell Self-Renewal and Transformation
- (2013) Su Jung Song et al. Cell Stem Cell
- Chromatin connectivity maps reveal dynamic promoter–enhancer long-range associations
- (2013) Yubo Zhang et al. NATURE
- Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy
- (2013) Alejandra Sanjuan-Pla et al. NATURE
- Large conserved domains of low DNA methylation maintained by Dnmt3a
- (2013) Mira Jeong et al. NATURE GENETICS
- TETonic shift: biological roles of TET proteins in DNA demethylation and transcription
- (2013) William A. Pastor et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia
- (2013) NEW ENGLAND JOURNAL OF MEDICINE
- An Extensive Network of TET2-Targeting MicroRNAs Regulates Malignant Hematopoiesis
- (2013) Jijun Cheng et al. Cell Reports
- Recurrent TET2 mutations in peripheral T-cell lymphomas correlate with TFH-like features and adverse clinical parameters
- (2012) F. Lemonnier et al. BLOOD
- TET2andDNMT3AMutations in Human T-Cell Lymphoma
- (2012) Lucile Couronné et al. NEW ENGLAND JOURNAL OF MEDICINE
- CD48 on hematopoietic progenitors regulates stem cells and suppresses tumor formation
- (2011) N. C. Boles et al. BLOOD
- Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies
- (2011) Z. Li et al. BLOOD
- TET2 Inactivation Results in Pleiotropic Hematopoietic Abnormalities in Mouse and Is a Recurrent Event during Human Lymphomagenesis
- (2011) Cyril Quivoron et al. CANCER CELL
- Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases
- (2011) Wei Xu et al. CANCER CELL
- Tet2 Loss Leads to Increased Hematopoietic Stem Cell Self-Renewal and Myeloid Transformation
- (2011) Kelly Moran-Crusio et al. CANCER CELL
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- TET Family Proteins and Their Role in Stem Cell Differentiation and Transformation
- (2011) Luisa Cimmino et al. Cell Stem Cell
- CpG islands and the regulation of transcription
- (2011) A. M. Deaton et al. GENES & DEVELOPMENT
- TET2 promoter methylation in low-grade diffuse gliomas lacking IDH1/2 mutations
- (2011) Y.-H. Kim et al. JOURNAL OF CLINICAL PATHOLOGY
- A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia
- (2011) Apostolos Klinakis et al. NATURE
- Dnmt3a is essential for hematopoietic stem cell differentiation
- (2011) Grant A Challen et al. NATURE GENETICS
- Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice
- (2011) M. Ko et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA
- (2011) Y.-F. He et al. SCIENCE
- Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine
- (2011) S. Ito et al. SCIENCE
- Dynamic changes in the human methylome during differentiation
- (2010) L. Laurent et al. GENOME RESEARCH
- The DNA Damage Response: Making It Safe to Play with Knives
- (2010) Alberto Ciccia et al. MOLECULAR CELL
- Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2
- (2010) Myunggon Ko et al. NATURE
- Comprehensive methylome map of lineage commitment from haematopoietic progenitors
- (2010) Hong Ji et al. NATURE
- The Behaviour of 5-Hydroxymethylcytosine in Bisulfite Sequencing
- (2010) Yun Huang et al. PLoS One
- IDH mutations in glioma and acute myeloid leukemia
- (2010) Lenny Dang et al. TRENDS IN MOLECULAR MEDICINE
- Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies
- (2009) O. Abdel-Wahab et al. BLOOD
- Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development
- (2009) M. A. Inlay et al. GENES & DEVELOPMENT
- Genome-wide Lineage-Specific Transcriptional Networks Underscore Ikaros-Dependent Lymphoid Priming in Hematopoietic Stem Cells
- (2009) Samuel Yao-Ming Ng et al. IMMUNITY
- Mutation inTET2in Myeloid Cancers
- (2009) François Delhommeau et al. NEW ENGLAND JOURNAL OF MEDICINE
- Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1
- (2009) M. Tahiliani et al. SCIENCE
- Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair
- (2008) Anne Wilson et al. CELL
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started