标题
STING: a master regulator in the cancer-immunity cycle
作者
关键词
-
出版物
Molecular Cancer
Volume 18, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-11-04
DOI
10.1186/s12943-019-1087-y
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Targeting DNA Damage Response Promotes Antitumor Immunity through STING-Mediated T-cell Activation in Small Cell Lung Cancer
- (2019) Triparna Sen et al. Cancer Discovery
- Autophagy induction via STING trafficking is a primordial function of the cGAS pathway
- (2019) Xiang Gui et al. NATURE
- STING signaling remodels the tumor microenvironment by antagonizing myeloid-derived suppressor cell expansion
- (2019) Chuan-xia Zhang et al. CELL DEATH AND DIFFERENTIATION
- PARP Inhibitor Efficacy Depends on CD8+ T-cell Recruitment via Intratumoral STING Pathway Activation in BRCA-Deficient Models of Triple-Negative Breast Cancer
- (2019) Constantia Pantelidou et al. Cancer Discovery
- STING agonist inflames the pancreatic cancer immune microenvironment and reduces tumor burden in mouse models
- (2019) Weiqing Jing et al. Journal for ImmunoTherapy of Cancer
- STING activation reprograms tumor vasculatures and synergizes with VEGFR2 blockade
- (2019) Hannah Yang et al. JOURNAL OF CLINICAL INVESTIGATION
- SnapShot: CGAS-STING Signaling
- (2018) Lorenzo Galluzzi et al. CELL
- Inflammation-Induced, STING-Dependent Autophagy Restricts Zika Virus Infection in the Drosophila Brain
- (2018) Yuan Liu et al. Cell Host & Microbe
- An overview on Vadimezan (DMXAA): The vascular disrupting agent
- (2018) Amir Daei Farshchi Adli et al. Chemical Biology & Drug Design
- Immune suppression and reversal of the suppressive tumor microenvironment
- (2018) Kanako Shimizu et al. INTERNATIONAL IMMUNOLOGY
- STING-Dependent Interferon-λ1 Induction in HT29 Cells, a Human Colorectal Cancer Cell Line, After Gamma-Radiation
- (2018) Jianzhou Chen et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Chromosomal instability drives metastasis through a cytosolic DNA response
- (2018) Samuel F. Bakhoum et al. NATURE
- STING activation enhances cetuximab-mediated NK cell activation and DC maturation and correlates with HPV + status in head and neck cancer
- (2018) Shanhong Lu et al. ORAL ONCOLOGY
- STING agonist therapy in combination with PD-1 immune checkpoint blockade enhances response to carboplatin chemotherapy in high-grade serous ovarian cancer
- (2018) Abdi Ghaffari et al. BRITISH JOURNAL OF CANCER
- Evaluation of explant responses to STING ligands: personalized immunosurgical therapy for head and neck squamous cell carcinoma
- (2018) Jason R. Baird et al. CANCER RESEARCH
- Interferon-β signal may up-regulate PD-L1 expression through IRF9-dependent and independent pathways in lung cancer cells
- (2018) Yoshie Morimoto et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Peptide-Based Nanoparticles to Rapidly and Efficiently “Wrap ’n Roll” siRNA into Cells
- (2018) Karidia Konate et al. BIOCONJUGATE CHEMISTRY
- STING promotes homeostasis via regulation of cell proliferation and chromosomal stability
- (2018) Diana Rose E. Ranoa et al. CANCER RESEARCH
- STING directly activates autophagy to tune the innate immune response
- (2018) Dong Liu et al. CELL DEATH AND DIFFERENTIATION
- Novel non-nucleotidic STING agonists for cancer immunotherapy
- (2018) Gilles Berger et al. Future Medicinal Chemistry
- Tumor-Derived cGAMP Triggers a STING-Mediated Interferon Response in Non-tumor Cells to Activate the NK Cell Response
- (2018) Assaf Marcus et al. IMMUNITY
- Type I IFN blockade uncouples immunotherapy-induced antitumor immunity and autoimmune toxicity
- (2018) Scott R. Walsh et al. JOURNAL OF CLINICAL INVESTIGATION
- Design of amidobenzimidazole STING receptor agonists with systemic activity
- (2018) Joshi M. Ramanjulu et al. NATURE
- An Analysis of the Expression and Association with Immune Cell Infiltration of the cGAS/STING Pathway in Pan-Cancer
- (2018) Xiang An et al. Molecular Therapy-Nucleic Acids
- PARP inhibition enhances tumor cell–intrinsic immunity in ERCC1-deficient non–small cell lung cancer
- (2018) Roman M. Chabanon et al. JOURNAL OF CLINICAL INVESTIGATION
- A prosurvival DNA damage-induced cytoplasmic interferon response is mediated by end resection factors and is limited by Trex1
- (2017) Erkin Erdal et al. GENES & DEVELOPMENT
- Induction of tumor regression by intratumoral STING agonists combined with anti-programmed death-L1 blocking antibody in a preclinical squamous cell carcinoma model
- (2017) Shekhar K. Gadkaree et al. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
- Intrinsic antiproliferative activity of the innate sensor STING in T lymphocytes
- (2017) Silvia Cerboni et al. JOURNAL OF EXPERIMENTAL MEDICINE
- DNA-Containing Exosomes Derived from Cancer Cells Treated with Topotecan Activate a STING-Dependent Pathway and Reinforce Antitumor Immunity
- (2017) Yuichi Kitai et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: Activation of STING in T Cells Induces Type I IFN Responses and Cell Death
- (2017) Bridget Larkin et al. JOURNAL OF IMMUNOLOGY
- MHC class II expression in lung cancer
- (2017) Yayi He et al. LUNG CANCER
- Expression of the MHC class II in triple-negative breast cancer is associated with tumor-infiltrating lymphocytes and interferon signaling
- (2017) In Ah Park et al. PLoS One
- cGAS is essential for the antitumor effect of immune checkpoint blockade
- (2017) Hua Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Host STING-dependent MDSC mobilization drives extrinsic radiation resistance
- (2017) Hua Liang et al. Nature Communications
- Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression
- (2017) Angel Garcia-Diaz et al. Cell Reports
- Intratumoral STING Activation with T-cell Checkpoint Modulation Generates Systemic Antitumor Immunity
- (2017) Casey R. Ager et al. Cancer Immunology Research
- Type I IFN and not TNF, is Essential for Cyclic Di-nucleotide-elicited CTL by a Cytosolic Cross-presentation Pathway
- (2017) Darío Lirussi et al. EBioMedicine
- Agonist-Mediated Activation of STING Induces Apoptosis in Malignant B Cells
- (2016) Chih-Hang Anthony Tang et al. CANCER RESEARCH
- STING Promotes the Growth of Tumors Characterized by Low Antigenicity via IDO Activation
- (2016) Henrique Lemos et al. CANCER RESEARCH
- Innate immune signaling and regulation in cancer immunotherapy
- (2016) Leticia Corrales et al. CELL RESEARCH
- The DNA Structure-Specific Endonuclease MUS81 Mediates DNA Sensor STING-Dependent Host Rejection of Prostate Cancer Cells
- (2016) Samantha S.W. Ho et al. IMMUNITY
- cGAS-cGAMP-STING: The three musketeers of cytosolic DNA sensing and signaling
- (2016) Jianli Tao et al. IUBMB LIFE
- Carcinoma–astrocyte gap junctions promote brain metastasis by cGAMP transfer
- (2016) Qing Chen et al. NATURE
- IDO in the Tumor Microenvironment: Inflammation, Counter-Regulation, and Tolerance
- (2016) David H. Munn et al. TRENDS IN IMMUNOLOGY
- Intracellular STING inactivation sensitizes breast cancer cells to genotoxic agents
- (2016) Julie Gaston et al. Oncotarget
- STING Pathway Activation Stimulates Potent Immunity against Acute Myeloid Leukemia
- (2016) Emily Curran et al. Cell Reports
- Established T Cell-Inflamed Tumors Rejected after Adaptive Resistance Was Reversed by Combination STING Activation and PD-1 Pathway Blockade
- (2016) E. Moore et al. Cancer Immunology Research
- Innate Immune Pattern Recognition: A Cell Biological Perspective
- (2015) Sky W. Brubaker et al. Annual Review of Immunology
- EBP1 protein modulates the expression of human MHC class II molecules in non-hematopoietic cancer cells
- (2015) LAURA PISAPIA et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- NOD-Like Receptors: Versatile Cytosolic Sentinels
- (2015) Vinicius Motta et al. PHYSIOLOGICAL REVIEWS
- STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity
- (2015) Olivier Demaria et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Viruses transfer the antiviral second messenger cGAMP between cells
- (2015) A. Bridgeman et al. SCIENCE
- Transmission of innate immune signaling by packaging of cGAMP in viral particles
- (2015) Matteo Gentili et al. SCIENCE
- STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade
- (2015) Juan Fu et al. Science Translational Medicine
- The STING pathway and the T cell-inflamed tumor microenvironment
- (2015) Seng-Ryong Woo et al. TRENDS IN IMMUNOLOGY
- Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity
- (2015) Leticia Corrales et al. Cell Reports
- STING-Dependent Cytosolic DNA Sensing Mediates Innate Immune Recognition of Immunogenic Tumors
- (2014) Seng-Ryong Woo et al. IMMUNITY
- STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors
- (2014) Liufu Deng et al. IMMUNITY
- DMXAA Causes Tumor Site-Specific Vascular Disruption in Murine Non-Small Cell Lung Cancer, and like the Endogenous Non-Canonical Cyclic Dinucleotide STING Agonist, 2′3′-cGAMP, Induces M2 Macrophage Repolarization
- (2014) Charlene M. Downey et al. PLoS One
- Cyclic GMP-AMP Displays Mucosal Adjuvant Activity in Mice
- (2014) Ivana Škrnjug et al. PLoS One
- STING Contributes to Antiglioma Immunity via Triggering Type I IFN Signals in the Tumor Microenvironment
- (2014) T. Ohkuri et al. Cancer Immunology Research
- STING Ligand c-di-GMP Improves Cancer Vaccination against Metastatic Breast Cancer
- (2014) D. Chandra et al. Cancer Immunology Research
- Host Restriction Factor SAMHD1 Limits Human T Cell Leukemia Virus Type 1 Infection of Monocytes via STING-Mediated Apoptosis
- (2013) Alexandre Sze et al. Cell Host & Microbe
- Targeting Toll-like receptors with small molecule agents
- (2013) Xiaohui Wang et al. CHEMICAL SOCIETY REVIEWS
- Nucleic acid driven sterile inflammation
- (2013) Andrea Ablasser et al. CLINICAL IMMUNOLOGY
- Deciphering and Reversing Tumor Immune Suppression
- (2013) Greg T. Motz et al. IMMUNITY
- Oncology Meets Immunology: The Cancer-Immunity Cycle
- (2013) Daniel S. Chen et al. IMMUNITY
- Cutting Edge: DNA Sensing via the STING Adaptor in Myeloid Dendritic Cells Induces Potent Tolerogenic Responses
- (2013) L. Huang et al. JOURNAL OF IMMUNOLOGY
- Mouse, but not Human STING, Binds and Signals in Response to the Vascular Disrupting Agent 5,6-Dimethylxanthenone-4-Acetic Acid
- (2013) J. Conlon et al. JOURNAL OF IMMUNOLOGY
- Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP
- (2013) Andrea Ablasser et al. NATURE
- STING-IRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease
- (2013) J. Petrasek et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Chemokine Superfamily Revisited
- (2012) Albert Zlotnik et al. IMMUNITY
- Structural and dynamic determinants of type I interferon receptor assembly and their functional interpretation
- (2012) Jacob Piehler et al. IMMUNOLOGICAL REVIEWS
- 5,6-Dimethylxanthenone-4-acetic Acid (DMXAA) Activates Stimulator of Interferon Gene (STING)-dependent Innate Immune Pathways and Is Regulated by Mitochondrial Membrane Potential
- (2012) Daniel Prantner et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Engineering DNA Nanoparticles as Immunomodulatory Reagents that Activate Regulatory T Cells
- (2012) L. Huang et al. JOURNAL OF IMMUNOLOGY
- Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA
- (2012) J. Wu et al. SCIENCE
- Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
- (2012) L. Sun et al. SCIENCE
- The pros and cons of chemokines in tumor immunology
- (2012) Antonella Viola et al. TRENDS IN IMMUNOLOGY
- Randomized Phase III Placebo-Controlled Trial of Carboplatin and Paclitaxel With or Without the Vascular Disrupting Agent Vadimezan (ASA404) in Advanced Non–Small-Cell Lung Cancer
- (2011) Primo N. Lara et al. JOURNAL OF CLINICAL ONCOLOGY
- Host type I IFN signals are required for antitumor CD8+T cell responses through CD8α+dendritic cells
- (2011) Mercedes B. Fuertes et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Type I interferon is selectively required by dendritic cells for immune rejection of tumors
- (2011) Mark S. Diamond et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Antiangiogenic therapy: impact on invasion, disease progression and metastasis
- (2011) John M. L. Ebos et al. Nature Reviews Clinical Oncology
- Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice
- (2011) M. Michaud et al. SCIENCE
- Decoding Cell Death Signals in Inflammation and Immunity
- (2010) Laurence Zitvogel et al. CELL
- Pattern Recognition Receptors and Inflammation
- (2010) Osamu Takeuchi et al. CELL
- The PD-1 pathway in tolerance and autoimmunity
- (2010) Loise M. Francisco et al. IMMUNOLOGICAL REVIEWS
- Identifying potential synergies and trade-offs for meeting food security and climate change objectives in sub-Saharan Africa
- (2010) C. A. Palm et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Aryl hydrocarbon receptor negatively regulates dendritic cell immunogenicity via a kynurenine-dependent mechanism
- (2010) N. T. Nguyen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Chemokine Expression in Melanoma Metastases Associated with CD8+ T-Cell Recruitment
- (2009) H. Harlin et al. CANCER RESEARCH
- DNA Makes RNA Makes Innate Immunity
- (2009) Luke A.J. O'Neill CELL
- Tumor and Host-Mediated Pathways of Resistance and Disease Progression in Response to Antiangiogenic Therapy
- (2009) J. M. L. Ebos et al. CLINICAL CANCER RESEARCH
- STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
- (2009) Hiroki Ishikawa et al. NATURE
- ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization
- (2009) W. Sun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Halofuginone Inhibits TH17 Cell Differentiation by Activating the Amino Acid Starvation Response
- (2009) M. S. Sundrud et al. SCIENCE
- The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation
- (2008) Bo Zhong et al. IMMUNITY
- IFN-β-Dependent Inhibition of Tumor Growth by the Vascular Disrupting Agent 5,6-Dimethylxanthenone-4-Acetic Acid (DMXAA)
- (2008) Zachary J. Roberts et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- MPYS, a Novel Membrane Tetraspanner, Is Associated with Major Histocompatibility Complex Class II and Mediates Transduction of Apoptotic Signals
- (2008) L. Jin et al. MOLECULAR AND CELLULAR BIOLOGY
- STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
- (2008) Hiroki Ishikawa et al. NATURE
- An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer
- (2008) R. R. Weichselbaum et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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