Actin cytoskeletal remodeling with protrusion formation is essential for heart regeneration in Hippo-deficient mice

Vinculin and Talin

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Hippo Pathway Effectors Control Cardiac Progenitor Cell Fate by Acting as Dynamic Sensors of Substrate Mechanics and Nanostructure

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Cardiac-Specific YAP Activation Improves Cardiac Function and Survival in an Experimental Murine MI Model

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FAK is required for tension-dependent organization of collective cell movements in Xenopus mesendoderm

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Enhancer loops appear stable during development and are associated with paused polymerase

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Obesity-associated variants within FTO form long-range functional connections with IRX3

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Noncontact quantitative biomechanical characterization of cardiac muscle using shear wave imaging optical coherence tomography

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Rapid and Pervasive Changes in Genome-wide Enhancer Usage during Mammalian Development

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A Mechanical Checkpoint Controls Multicellular Growth through YAP/TAZ Regulation by Actin-Processing Factors

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Hippo signaling impedes adult heart regeneration

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The Hippo pathway: regulators and regulations

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Genetic mutations and mechanisms in dilated cardiomyopathy

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Signaling effectors underlying pathologic growth and remodeling of the heart

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Specific deletion of Cdc42 does not affect meiotic spindle organization/migration and homologous chromosome segregation but disrupts polarity establishment and cytokinesis in mouse oocytes

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Topology of mammalian developmental enhancers and their regulatory landscapes

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DNase I–hypersensitive exons colocalize with promoters and distal regulatory elements

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Multiplexed chromosome conformation capture sequencing for rapid genome-scale high-resolution detection of long-range chromatin interactions

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Functions of cofilin in cell locomotion and invasion

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Hippo pathway effector Yap promotes cardiac regeneration

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Cardiac Regenerative Capacity and Mechanisms

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Cyclin-dependent kinase inhibitor 3 is overexpressed in hepatocellular carcinoma and promotes tumor cell proliferation

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The MuvB complex sequentially recruits B-Myb and FoxM1 to promote mitotic gene expression

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Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP

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Loss of αT-catenin alters the hybrid adhering junctions in the heart and leads to dilated cardiomyopathy and ventricular arrhythmia following acute ischemia

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Determining long-range chromatin interactions for selected genomic sites using 4C-seq technology: From fixation to computation

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An expansive human regulatory lexicon encoded in transcription factor footprints

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The accessible chromatin landscape of the human genome

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YAP1, the nuclear target of Hippo signaling, stimulates heart growth through cardiomyocyte proliferation but not hypertrophy

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Matrix Rigidity Controls Endothelial Differentiation and Morphogenesis of Cardiac Precursors

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Life at the Leading Edge

(2011) Anne J. Ridley   CELL

MIM regulates vertebrate neural tube closure

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A kinase shRNA screen links LATS2 and the pRB tumor suppressor

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Therapeutic approaches to muscular dystrophy

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Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia

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Role of YAP/TAZ in mechanotransduction

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An integrated semiconductor device enabling non-optical genome sequencing

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Hippo Pathway Inhibits Wnt Signaling to Restrain Cardiomyocyte Proliferation and Heart Size

(2011) T. Heallen et al.   SCIENCE

Transient Regenerative Potential of the Neonatal Mouse Heart

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Energy Metabolic Phenotype of the Cardiomyocyte During Development, Differentiation, and Postnatal Maturation

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Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

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Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation

(2010) Chris Jopling et al.   NATURE

The NIH Roadmap Epigenomics Mapping Consortium

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Collective cell migration in morphogenesis, regeneration and cancer

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Evidence for Cardiomyocyte Renewal in Humans

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Mechanisms of Muscle Degeneration, Regeneration, and Repair in the Muscular Dystrophies

(2008) Gregory Q. Wallace et al.   Annual Review of Physiology