Effects of substrate stiffness and actomyosin contractility on coupling between force transmission and vinculin–paxillin recruitment at single focal adhesions

Vinculin promotes nuclear localization of TAZ to inhibit ECM stiffness-dependent differentiation into adipocytes

(2017) Mito Kuroda et al.   JOURNAL OF CELL SCIENCE

Vinculin head–tail interaction defines multiple early mechanisms for cell substrate rigidity sensing

(2016) Zengzhen Liu et al.   Integrative Biology

Mechanical regulation of a molecular clutch defines force transmission and transduction in response to matrix rigidity

(2016) Alberto Elosegui-Artola et al.   NATURE CELL BIOLOGY

Mechanosensitive subcellular rheostasis drives emergent single-cell mechanical homeostasis

(2016) Shinuo Weng et al.   NATURE MATERIALS

Molecular mechanism of vinculin activation and nanoscale spatial organization in focal adhesions

(2015) Lindsay B. Case et al.   NATURE CELL BIOLOGY

Extracellular rigidity sensing by talin isoform-specific mechanical linkages

(2015) Katharina Austen et al.   NATURE CELL BIOLOGY

Vinculin controls talin engagement with the actomyosin machinery

(2015) Paul Atherton et al.   Nature Communications

Stressing the limits of focal adhesion mechanosensitivity

(2014) Patrick W Oakes et al.   CURRENT OPINION IN CELL BIOLOGY

The role of the interaction of the vinculin proline-rich linker region with vinexin   in sensing the stiffness of the extracellular matrix

(2014) H. Yamashita et al.   JOURNAL OF CELL SCIENCE

Forces in Tissue Morphogenesis and Patterning

(2013) Carl-Philipp Heisenberg et al.   CELL

Vinculin Regulates the Recruitment and Release of Core Focal Adhesion Proteins in a Force-Dependent Manner

(2013) Alex Carisey et al.   CURRENT BIOLOGY

How vinculin regulates force transmission

(2013) D. W. Dumbauld et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Force Fluctuations within Focal Adhesions Mediate ECM-Rigidity Sensing to Guide Directed Cell Migration

(2012) Sergey V. Plotnikov et al.   CELL

Nanopatterning reveals an ECM area threshold for focal adhesion assembly and force transmission that is regulated by integrin activation and cytoskeleton tension

(2012) S. R. Coyer et al.   JOURNAL OF CELL SCIENCE

Spatiotemporal Constraints on the Force-Dependent Growth of Focal Adhesions

(2011) Jonathan Stricker et al.   BIOPHYSICAL JOURNAL

Actomyosin-generated tension controls the molecular kinetics of focal adhesions

(2011) H. Wolfenson et al.   JOURNAL OF CELL SCIENCE

Mechanical signaling through the cytoskeleton regulates cell proliferation by coordinated focal adhesion and Rho GTPase signaling

(2011) P. P. Provenzano et al.   JOURNAL OF CELL SCIENCE

Assaying stem cell mechanobiology on microfabricated elastomeric substrates with geometrically modulated rigidity

(2011) Michael T Yang et al.   Nature Protocols

Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation

(2010) Ana M. Pasapera et al.   JOURNAL OF CELL BIOLOGY

Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics

(2010) Carsten Grashoff et al.   NATURE

Nanoscale architecture of integrin-based cell adhesions

(2010) Pakorn Kanchanawong et al.   NATURE

Mechanical regulation of cell function with geometrically modulated elastomeric substrates

(2010) Jianping Fu et al.   NATURE METHODS

Stretching Single Talin Rod Molecules Activates Vinculin Binding

(2009) A. del Rio et al.   SCIENCE

Proteomic Analysis of Integrin-Associated Complexes Identifies RCC2 as a Dual Regulator of Rac1 and Arf6

(2009) J. D. Humphries et al.   Science Signaling

Investigating complexity of protein–protein interactions in focal adhesions

(2008) Tanmay P. Lele et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Lipid Binding to the Tail Domain of Vinculin

(2008) Sean M. Palmer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Paxillin comes of age

(2008) N. O. Deakin et al.   JOURNAL OF CELL SCIENCE

High Resolution Traction Force Microscopy Based on Experimental and Computational Advances

(2007) Benedikt Sabass et al.   BIOPHYSICAL JOURNAL