Talin1 phosphorylation activates β1 integrins: a novel mechanism to promote prostate cancer bone metastasis

Mechanisms of talin-dependent integrin signaling and crosstalk

(2013) Mitali Das et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

CCL2 increases αvβ3 integrin expression and subsequently promotes prostate cancer migration

(2013) Tien-Huang Lin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Trop-2 Promotes Prostate Cancer Metastasis By Modulating  1 Integrin Functions

(2013) M. Trerotola et al.   CANCER RESEARCH

The Mechanism of Kindlin-Mediated Activation of Integrin αIIbβ3

(2013) Feng Ye et al.   CURRENT BIOLOGY

Cancer incidence and mortality patterns in Europe: Estimates for 40 countries in 2012

(2013) J. Ferlay et al.   EUROPEAN JOURNAL OF CANCER

Ligand-independent activation of MET through IGF-1/IGF-1R signaling

(2013) Andreas Varkaris et al.   INTERNATIONAL JOURNAL OF CANCER

Structural studies on full-length talin1 reveal a compact auto-inhibited dimer: Implications for talin activation

(2013) Benjamin T. Goult et al.   JOURNAL OF STRUCTURAL BIOLOGY

Targeting Constitutively Activated β 1 Integrins Inhibits Prostate Cancer Metastasis

(2013) Yu-Chen Lee et al.   MOLECULAR CANCER RESEARCH

Talins and kindlins: partners in integrin-mediated adhesion

(2013) David A. Calderwood et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

IGF-IR Promotes Prostate Cancer Growth by Stabilizing α5β1 Integrin Protein Levels

(2013) Aejaz Sayeed et al.   PLoS One

Definition of Molecular Determinants of Prostate Cancer Cell Bone Extravasation

(2012) S. R. Barthel et al.   CANCER RESEARCH

Role of α5β1 and αvβ3 integrins in relation to adhesion and spreading dynamics of prostate cancer cells interacting with fibronectin underin vitroconditions

(2012) Anna Stachurska et al.   CELL BIOLOGY INTERNATIONAL

A novel membrane-dependent on/off switch mechanism of talin FERM domain at sites of cell adhesion

(2012) Xianqiang Song et al.   CELL RESEARCH

Integrin alpha2beta1 (α2β1) promotes prostate cancer skeletal metastasis

(2012) Joseph L. Sottnik et al.   CLINICAL & EXPERIMENTAL METASTASIS

Talin1 Has Unique ExpressionversusTalin 2 in the Heart and Modifies the Hypertrophic Response to Pressure Overload

(2012) Ana Maria Manso et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Steps in prostate cancer progression that lead to bone metastasis

(2011) Jung-Kang Jin et al.   INTERNATIONAL JOURNAL OF CANCER

Talin-1 overexpression defines high risk for aggressive oral squamous cell carcinoma and promotes cancer metastasis

(2011) Ming-Tsung Lai et al.   JOURNAL OF PATHOLOGY

Molecular mechanism of inside-out integrin regulation

(2011) F. YE et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Cadherin-11 regulates fibroblast inflammation

(2011) S. K. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Talin1 Promotes Tumor Invasion and Metastasis via Focal Adhesion Signaling and Anoikis Resistance

(2010) S. Sakamoto et al.   CANCER RESEARCH

Talin 2 is a large and complex gene encoding multiple transcripts and protein isoforms

(2009) Emmanuel Debrand et al.   FEBS Journal

Systemic Delivery of Synthetic MicroRNA-16 Inhibits the Growth of Metastatic Prostate Tumors via Downregulation of Multiple Cell-cycle Genes

(2009) Fumitaka Takeshita et al.   MOLECULAR THERAPY

Talin phosphorylation by Cdk5 regulates Smurf1-mediated talin head ubiquitylation and cell migration

(2009) Cai Huang et al.   NATURE CELL BIOLOGY

A Versatile Viral System for Expression and Depletion of Proteins in Mammalian Cells

(2009) Eric Campeau et al.   PLoS One

Talin at a glance

(2008) D. R. Critchley et al.   JOURNAL OF CELL SCIENCE