Muscular Dystrophy-Associated SUN1 and SUN2 Variants Disrupt Nuclear-Cytoskeletal Connections and Myonuclear Organization

Nuclear Mechanics and Mechanotransduction in Health and Disease

(2013) Philipp Isermann et al.   CURRENT BIOLOGY

Myopathic lamin mutations impair nuclear stability in cells and tissue and disrupt nucleo-cytoskeletal coupling

(2013) Monika Zwerger et al.   HUMAN MOLECULAR GENETICS

Familial partial lipodystrophy, mandibuloacral dysplasia and restrictive dermopathy feature barrier-to-autointegration factor (BAF) nuclear redistribution

(2012) Cristina Capanni et al.   CELL CYCLE

Inner nuclear membrane proteins: impact on human disease

(2012) Iván Méndez-López et al.   CHROMOSOMA

Muscle length and myonuclear position are independently regulated by distinct Dynein pathways

(2012) E. S. Folker et al.   DEVELOPMENT

Nuclear movement during myotube formation is microtubule and dynein dependent and is regulated by Cdc42, Par6 and Par3

(2012) Bruno Cadot et al.   EMBO REPORTS

LINC complex alterations in DMD and EDMD/CMT fibroblasts

(2012) Surayya Taranum et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Organelle positioning in muscles requires cooperation between two KASH proteins and microtubules

(2012) Hadas Elhanany-Tamir et al.   JOURNAL OF CELL BIOLOGY

Samp1 is a component of TAN lines and is required for nuclear movement

(2012) J. Borrego-Pinto et al.   JOURNAL OF CELL SCIENCE

Opposing microtubule motors drive robust nuclear dynamics in developing muscle cells

(2012) Meredith H. Wilson et al.   JOURNAL OF CELL SCIENCE

MAP and kinesin-dependent nuclear positioning is required for skeletal muscle function

(2012) Thomas Metzger et al.   NATURE

The LINC complex and human disease

(2011) Peter Meinke et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Prelamin A-mediated recruitment of SUN1 to the nuclear envelope directs nuclear positioning in human muscle

(2011) E Mattioli et al.   CELL DEATH AND DIFFERENTIATION

Samp1 is functionally associated with the LINC complex and A-type lamina networks

(2011) S. Gudise et al.   JOURNAL OF CELL SCIENCE

Uncoordinated Transcription and Compromised Muscle Function in the Lmna-Null Mouse Model of Emery-Dreifuss Muscular Dystrophy

(2011) Viola F. Gnocchi et al.   PLoS One

TMEM43 mutations in emery-dreifuss muscular dystrophy-related myopathy

(2010) Wen-Chen Liang et al.   ANNALS OF NEUROLOGY

Interactions Between Nuclei and the Cytoskeleton Are Mediated by SUN-KASH Nuclear-Envelope Bridges

(2010) Daniel A. Starr et al.   Annual Review of Cell and Developmental Biology

Molecular mechanisms of centrosome and cytoskeleton anchorage at the nuclear envelope

(2010) Maria Schneider et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Importance of Genetic Counseling, DNA Diagnostics, and Cardiologic Family Screening in Left Ventricular Noncompaction Cardiomyopathy

(2010) Yvonne M. Hoedemaekers et al.   Circulation-Cardiovascular Genetics

Nesprins, but not sun proteins, switch isoforms at the nuclear envelope during muscle development

(2010) K. Natalie Randles et al.   DEVELOPMENTAL DYNAMICS

Modifier locus of the skeletal muscle involvement in Emery–Dreifuss muscular dystrophy

(2010) B. Granger et al.   HUMAN GENETICS

Interfering with the connection between the nucleus and the cytoskeleton affects nuclear rotation, mechanotransduction and myogenesis

(2010) Michaela Brosig et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Lamin A variants that cause striated muscle disease are defective in anchoring transmembrane actin-associated nuclear lines for nuclear movement

(2010) E. S. Folker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Linear Arrays of Nuclear Envelope Proteins Harness Retrograde Actin Flow for Nuclear Movement

(2010) G. W. G. Luxton et al.   SCIENCE

Lamin-binding Proteins

(2010) K. L. Wilson et al.   Cold Spring Harbor Perspectives in Biology

Mutations of the FHL1 Gene Cause Emery-Dreifuss Muscular Dystrophy

(2009) Lucie Gueneau et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Emerin-prelamin A interplay in human fibroblasts

(2009) Cristina Capanni et al.   BIOLOGY OF THE CELL

Centrosome proteins form an insoluble perinuclear matrix during muscle cell differentiation

(2009) Vlastimil Srsen et al.   BMC CELL BIOLOGY

Nesprin 1 is critical for nuclear positioning and anchorage

(2009) Jianlin Zhang et al.   HUMAN MOLECULAR GENETICS

Mammalian SUN Protein Interaction Networks at the Inner Nuclear Membrane and Their Role in Laminopathy Disease Processes

(2009) Farhana Haque et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lamin A/C–mediated neuromuscular junction defects in Emery-Dreifuss muscular dystrophy

(2009) Alexandre Méjat et al.   JOURNAL OF CELL BIOLOGY

Bringing KASH under the SUN: the many faces of nucleo-cytoskeletal connections

(2009) David Razafsky et al.   JOURNAL OF CELL BIOLOGY

SUN1/2 and Syne/Nesprin-1/2 Complexes Connect Centrosome to the Nucleus during Neurogenesis and Neuronal Migration in Mice

(2009) Xiaochang Zhang et al.   NEURON

Nesprin 4 is an outer nuclear membrane protein that can induce kinesin-mediated cell polarization

(2009) K. J. Roux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SUN1 and SUN2 play critical but partially redundant roles in anchoring nuclei in skeletal muscle cells in mice

(2009) K. Lei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extreme phenotypic diversity and nonpenetrance in families with theLMNA gene mutation R644C

(2008) Julia Rankin et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin

(2008) T. Dechat et al.   GENES & DEVELOPMENT

Lamin A Ser404 Is a Nuclear Target of Akt Phosphorylation in C2C12 Cells

(2008) Vittoria Cenni et al.   JOURNAL OF PROTEOME RESEARCH