- Home
- Publications
- Publication Search
- Publication Details
Title
ROS and Trypanosoma cruzi: Fuel to infection, poison to the heart
Authors
Keywords
Parasitic diseases, Macrophages, Respiratory infections, Trypanosoma cruzi, Antioxidants, Heart, Oxidative damage, Oxidative stress
Journal
PLoS Pathogens
Volume 14, Issue 4, Pages e1006928
Publisher
Public Library of Science (PLoS)
Online
2018-04-20
DOI
10.1371/journal.ppat.1006928
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Heme modulates Trypanosoma cruzi bioenergetics inducing mitochondrial ROS production
- (2017) Natália P. Nogueira et al. FREE RADICAL BIOLOGY AND MEDICINE
- MIF-driven activation of macrophages induces killing of intracellular Trypanosoma cruzi dependent on endogenous production of tumor necrosis factor, nitric oxide and reactive oxygen species
- (2017) Romina A. Cutrullis et al. IMMUNOBIOLOGY
- The mechanisms of ventricular arrhythmia in Chagas disease
- (2017) Andrew Tinker INTERNATIONAL JOURNAL OF CARDIOLOGY
- Autoantibodies with beta-adrenergic activity from chronic chagasic patients induce cardiac arrhythmias and early afterdepolarization in a drug-induced LQT2 rabbit hearts
- (2017) Marco Antonio Vidal Jiménez et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Overexpression of HO-1 Contributes to Sepsis-Induced Immunosuppression by Modulating the Th1/Th2 Balance and Regulatory T-Cell Function
- (2017) Seong-Jin Yoon et al. JOURNAL OF INFECTIOUS DISEASES
- Kinetics, subcellular localization, and contribution to parasite virulence of aTrypanosoma cruzihybrid type A heme peroxidase (TcAPx-CcP)
- (2017) Martín Hugo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cardiomyocyte oxidants production may signal to T. cruzi intracellular development
- (2017) Patrícia Pereira Dias et al. PLoS Neglected Tropical Diseases
- Comparative effects of histone deacetylases inhibitors and resveratrol on Trypanosoma cruzi replication, differentiation, infectivity and gene expression
- (2017) Vanina A. Campo International Journal for Parasitology-Drugs and Drug Resistance
- Impact of the Use of Benznidazole Followed by Antioxidant Supplementation in the Prevalence of Ventricular Arrhythmias in Patients With Chronic Chagas Disease
- (2016) João Luís Barbosa et al. AMERICAN JOURNAL OF THERAPEUTICS
- Antioxidant effects of resveratrol in the cardiovascular system
- (2016) Ning Xia et al. BRITISH JOURNAL OF PHARMACOLOGY
- Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism
- (2016) Agnieszka Loboda et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Oxidative stress and myocarditis
- (2016) Yuko Tada et al. CURRENT PHARMACEUTICAL DESIGN
- The Aryl Hydrocarbon Receptor Modulates Production of Cytokines and Reactive Oxygen Species and Development of Myocarditis during Trypanosoma cruzi Infection
- (2016) Andréia Barroso et al. INFECTION AND IMMUNITY
- Resveratrol inhibits Trypanosoma cruzi arginine kinase and exerts a trypanocidal activity
- (2016) Edward A. Valera Vera et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- How Trypanosoma cruzi deals with oxidative stress: Antioxidant defence and DNA repair pathways
- (2016) Alice Machado-Silva et al. MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
- The trypanocidal benznidazole promotes adaptive response to oxidative injury: Involvement of the nuclear factor-erythroid 2-related factor-2 (Nrf2) and multidrug resistance associated protein 2 (MRP2)
- (2016) Juan Pablo Rigalli et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Macrophage-dependent IL-1β production induces cardiac arrhythmias in diabetic mice
- (2016) Gustavo Monnerat et al. Nature Communications
- Trypanosoma cruzi Needs a Signal Provided by Reactive Oxygen Species to Infect Macrophages
- (2016) Grazielle R. Goes et al. PLoS Neglected Tropical Diseases
- Resveratrol Reverses Functional Chagas Heart Disease in Mice
- (2016) Glaucia Vilar-Pereira et al. PLoS Pathogens
- SIRT1-PGC1α-NFκB Pathway of Oxidative and Inflammatory Stress during Trypanosoma cruzi Infection: Benefits of SIRT1-Targeted Therapy in Improving Heart Function in Chagas Disease
- (2016) Xianxiu Wan et al. PLoS Pathogens
- Randomized Trial of Benznidazole for Chronic Chagas’ Cardiomyopathy
- (2015) Carlos A. Morillo et al. NEW ENGLAND JOURNAL OF MEDICINE
- Proliferation and Differentiation of Trypanosoma cruzi inside Its Vector Have a New Trigger: Redox Status
- (2015) Natália P. Nogueira et al. PLoS One
- CaMKII oxidative activation and the pathogenesis of cardiac disease
- (2014) Elizabeth D. Luczak et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Reactive oxygen species and excitation–contraction coupling in the context of cardiac pathology
- (2014) Anne C. Köhler et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Tumor Necrosis Factor Is a Therapeutic Target for Immunological Unbalance and Cardiac Abnormalities in Chronic Experimental Chagas’ Heart Disease
- (2014) Isabela Resende Pereira et al. MEDIATORS OF INFLAMMATION
- Severity of chronic experimental Chagas' heart disease parallels tumour necrosis factor and nitric oxide levels in the serum: models of mild and severe disease
- (2014) Isabela Resende Pereira et al. MEMORIAS DO INSTITUTO OSWALDO CRUZ
- Markers of oxidative stress in adipose tissue during Trypanosoma cruzi infection
- (2014) Jian-Jun Wen et al. PARASITOLOGY RESEARCH
- Caspase-1/ASC Inflammasome-Mediated Activation of IL-1β–ROS–NF-κB Pathway for Control of Trypanosoma cruzi Replication and Survival Is Dispensable in NLRP3−/− Macrophages
- (2014) Nilay Dey et al. PLoS One
- Selenium Treatment and Chagasic Cardiopathy (STCC): study protocol for a double-blind randomized controlled trial
- (2014) Pedro Emmanuel Alvarenga Americano do Brasil et al. Trials
- Benznidazole Biotransformation and Multiple Targets in Trypanosoma cruzi Revealed by Metabolomics
- (2014) Andrea Trochine et al. PLoS Neglected Tropical Diseases
- P47phox−/− Mice Are Compromised in Expansion and Activation of CD8+ T Cells and Susceptible to Trypanosoma cruzi Infection
- (2014) Monisha Dhiman et al. PLoS Pathogens
- Quantifying intracellular hydrogen peroxide perturbations in terms of concentration
- (2014) Beijing K. Huang et al. Redox Biology
- Are Reactive Oxygen Species Always Detrimental to Pathogens?
- (2013) Claudia N. Paiva et al. ANTIOXIDANTS & REDOX SIGNALING
- Aryl hydrocarbon receptor protects against bacterial infection by promoting macrophage survival and reactive oxygen species production
- (2013) Akihiro Kimura et al. INTERNATIONAL IMMUNOLOGY
- Oxidative Stress and DNA Lesions: The Role of 8-Oxoguanine Lesions in Trypanosoma cruzi Cell Viability
- (2013) Pedro H. N. Aguiar et al. PLoS Neglected Tropical Diseases
- NLRP3 Controls Trypanosoma cruzi Infection through a Caspase-1-Dependent IL-1R-Independent NO Production
- (2013) Virginia M. Gonçalves et al. PLoS Neglected Tropical Diseases
- MnSOD tg Mice Control Myocardial Inflammatory and Oxidative Stress and Remodeling Responses Elicited in Chronic Chagas Disease
- (2013) Monisha Dhiman et al. Journal of the American Heart Association
- Trypanosoma cruzi Antioxidant Enzymes As Virulence Factors in Chagas Disease
- (2012) Lucía Piacenza et al. ANTIOXIDANTS & REDOX SIGNALING
- Redox Reactions and Microbial Killing in the Neutrophil Phagosome
- (2012) Christine C. Winterbourn et al. ANTIOXIDANTS & REDOX SIGNALING
- Ventricular Arrhythmias are Related to the Presence of Autoantibodies With Adrenergic Activity in Chronic Chagasic Patients With Preserved Left Ventricular Function
- (2012) Leonardo Maciel et al. JOURNAL OF CARDIAC FAILURE
- Oxidative stress fuels Trypanosoma cruzi infection in mice
- (2012) Claudia N. Paiva et al. JOURNAL OF CLINICAL INVESTIGATION
- Curcumin treatment provides protection against Trypanosoma cruzi infection
- (2012) Fnu Nagajyothi et al. PARASITOLOGY RESEARCH
- Cardiac-Oxidized Antigens Are Targets of Immune Recognition by Antibodies and Potential Molecular Determinants in Chagas Disease Pathogenesis
- (2012) Monisha Dhiman et al. PLoS One
- Disease Tolerance as a Defense Strategy
- (2012) R. Medzhitov et al. SCIENCE
- NADPH Phagocyte Oxidase Knockout Mice Control Trypanosoma cruzi Proliferation, but Develop Circulatory Collapse and Succumb to Infection
- (2012) Helton C. Santiago et al. PLoS Neglected Tropical Diseases
- The Receptor Slamf1 on the Surface of Myeloid Lineage Cells Controls Susceptibility to Infection by Trypanosoma cruzi
- (2012) Jossela Calderón et al. PLoS Pathogens
- Activation of Benznidazole by Trypanosomal Type I Nitroreductases Results in Glyoxal Formation
- (2011) Belinda S. Hall et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- NADPH oxidase inhibition ameliorates Trypanosoma cruzi-induced myocarditis during Chagas disease
- (2011) Monisha Dhiman et al. JOURNAL OF PATHOLOGY
- The benefits of using selenium in the treatment of Chagas disease: prevention of right ventricle chamber dilatation and reversion of Trypanosoma cruzi-induced acute and chronic cardiomyopathy in mice
- (2011) Andréa P de Souza et al. MEMORIAS DO INSTITUTO OSWALDO CRUZ
- How does the oxidative burst of macrophages kill bacteria? Still an open question
- (2011) James M. Slauch MOLECULAR MICROBIOLOGY
- Heme-Induced ROS in Trypanosoma Cruzi Activates CaMKII-Like That Triggers Epimastigote Proliferation. One Helpful Effect of ROS
- (2011) Natália Pereira de Almeida Nogueira et al. PLoS One
- AMPK and SIRT1: a long-standing partnership?
- (2010) Neil B. Ruderman et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- PGC-1 Coactivators in Cardiac Development and Disease
- (2010) Glenn C. Rowe et al. CIRCULATION RESEARCH
- Induction of NADPH oxidase activity and reactive oxygen species production by a single Trypanosoma cruzi antigen
- (2010) Natalia Guiñazú et al. INTERNATIONAL JOURNAL FOR PARASITOLOGY
- Intraphagosomal Peroxynitrite as a Macrophage-derived Cytotoxin against InternalizedTrypanosoma cruzi
- (2010) María Noel Alvarez et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Trypanosoma cruziInduces the Reactive Oxygen Species-PARP-1-RelA Pathway for Up-regulation of Cytokine Expression in Cardiomyocytes
- (2010) Xueqing Ba et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- ECG Detection of Murine Chagasic Cardiomyopathy
- (2010) Christopher S. Eickhoff et al. JOURNAL OF PARASITOLOGY
- Phenyl-α-tert-butyl-nitrone and Benzonidazole Treatment Controlled the Mitochondrial Oxidative Stress and Evolution of Cardiomyopathy in Chronic Chagasic Rats
- (2010) Jian-Jun Wen et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Mitochondrial Complex III Defects Contribute to Inefficient Respiration and ATP Synthesis in the Myocardium of Trypanosoma cruzi–Infected Mice
- (2009) Jian-Jun Wen et al. ANTIOXIDANTS & REDOX SIGNALING
- Fighting the oxidative assault: the Trypanosoma cruzi journey to infection
- (2009) Lucía Piacenza et al. CURRENT OPINION IN MICROBIOLOGY
- Myeloid heme oxygenase–1 regulates innate immunity and autoimmunity by modulating IFN-β production
- (2009) Sotiria Tzima et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Cruzipain and SP600125 induce p38 activation, alter NO/arginase balance and favor the survival of Trypanosoma cruzi in macrophages
- (2008) Cinthia C. Stempin et al. ACTA TROPICA
- Mitochondrial generation of reactive oxygen species is enhanced at the Qo site of the complex III in the myocardium of Trypanosoma cruzi-infected mice: beneficial effects of an antioxidant
- (2008) Jian-Jun Wen et al. JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
- Tissue-specific oxidative imbalance and mitochondrial dysfunction during Trypanosoma cruzi infection in mice
- (2008) J WEN et al. MICROBES AND INFECTION
- A mechanism for cross-resistance to nifurtimox and benznidazole in trypanosomes
- (2008) Shane R. Wilkinson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now