Oxidative stress fuels Trypanosoma cruzi infection in mice

A Novel IFN Regulatory Factor 3-Dependent Pathway Activated by Trypanosomes Triggers IFN-  in Macrophages and Fibroblasts

(2014) A.-D. C. Chessler et al.   JOURNAL OF IMMUNOLOGY

NADPH oxidase inhibition ameliorates Trypanosoma cruzi-induced myocarditis during Chagas disease

(2011) Monisha Dhiman et al.   JOURNAL OF PATHOLOGY

Host-mediated regulation of superinfection in malaria

(2011) Silvia Portugal et al.   NATURE MEDICINE

Inhibition of Nox2 Oxidase Activity Ameliorates Influenza A Virus-Induced Lung Inflammation

(2011) Ross Vlahos et al.   PLoS Pathogens

Mechanisms of Cell Protection by Heme Oxygenase-1

(2010) Raffaella Gozzelino et al.   Annual Review of Pharmacology and Toxicology

Dysfunction of the heme recycling system in heme oxygenase 1-deficient mice: effects on macrophage viability and tissue iron distribution

(2010) G. Kovtunovych et al.   BLOOD

The endless race between Trypanosoma cruzi and host immunity: lessons for and beyond Chagas disease

(2010) Caroline Junqueira et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

An oxidative environment promotes growth of Mycobacterium abscessus

(2010) Rebecca E. Oberley-Deegan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Heme controls ferroportin1 (FPN1) transcription involving Bach1, Nrf2 and a MARE/ARE sequence motif at position -7007 of the FPN1 promoter

(2010) S. Marro et al.   HAEMATOLOGICA

Intraphagosomal Peroxynitrite as a Macrophage-derived Cytotoxin against InternalizedTrypanosoma cruzi

(2010) María Noel Alvarez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heme Amplifies the Innate Immune Response to Microbial Molecules through Spleen Tyrosine Kinase (Syk)-dependent Reactive Oxygen Species Generation

(2010) Patricia L. Fernandez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Induction of Interleukin-6 Expression by Bone Morphogenetic Protein-6 in Macrophages Requires Both SMAD and p38 Signaling Pathways

(2010) Geun Taek Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

15d-PGJ2 modulates acute immune responses to Trypanosoma cruzi infection

(2010) Wellington F Rodrigues et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

The increase in intra-macrophage thiols induced by new pro-GSH molecules directs the Th1 skewing in ovalbumin immunized mice

(2010) Alessandra Fraternale et al.   VACCINE

Enterovirus 71 induces COX-2 expression via MAPKs, NF-κB, and AP-1 in SK–N–SH cells: Role of PGE2 in viral replication

(2009) Wei-Hsuan Tung et al.   CELLULAR SIGNALLING

CD8+ T cells in Trypanosoma cruzi infection

(2009) Angel M Padilla et al.   CURRENT OPINION IN IMMUNOLOGY

Trypanosoma cruzi infection disturbs mitochondrial membrane potential and ROS production rate in cardiomyocytes

(2009) Shivali Gupta et al.   FREE RADICAL BIOLOGY AND MEDICINE

The heme oxygenase 1 product biliverdin interferes with hepatitis C virus replication by increasing antiviral interferon response

(2009) Elisabeth Lehmann et al.   HEPATOLOGY

Myeloid heme oxygenase–1 regulates innate immunity and autoimmunity by modulating IFN-β production

(2009) Sotiria Tzima et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Innate Immunity against Bacterial Infection following Hyperoxia Exposure Is Impaired in NRF2-Deficient Mice

(2009) N. M. Reddy et al.   JOURNAL OF IMMUNOLOGY

Cytoprotective Function of Heme Oxygenase 1 Induced by a Nitrated Cyclic Nucleotide Formed during Murine Salmonellosis

(2009) M. H. Zaki et al.   JOURNAL OF IMMUNOLOGY

A systems biology perspective on Nrf2-mediated antioxidant response

(2009) Qiang Zhang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Antiviral Activity of Nrf2 in a Murine Model of Respiratory Syncytial Virus Disease

(2008) Hye-Youn Cho et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Heme Oxygenase-1 Is an Anti-Inflammatory Host Factor that Promotes Murine Plasmodium Liver Infection

(2008) Sabrina Epiphanio et al.   Cell Host & Microbe

Leishmania donovanidepletes labile iron pool to exploit iron uptake capacity of macrophage for its intracellular growth

(2008) Nupur Kanti Das et al.   CELLULAR MICROBIOLOGY

Heme oxygenase-1 suppresses hepatitis C virus replication and increases resistance of hepatocytes to oxidant injury

(2008) Zhaowen Zhu et al.   HEPATOLOGY

Heme oxygenase-1–derived carbon monoxide enhances the host defense response to microbial sepsis in mice

(2008) Su Wol Chung et al.   JOURNAL OF CLINICAL INVESTIGATION

GSH and analogs in antiviral therapy

(2008) Alessandra Fraternale et al.   MOLECULAR ASPECTS OF MEDICINE

Abnormal IFN-γ-dependent immunoproteasome modulation by Trypanosoma cruzi-infected macrophages

(2008) M. BERGERON et al.   PARASITE IMMUNOLOGY

Catalytic inactive heme oxygenase-1 protein regulates its own expression in oxidative stress

(2007) Qing S. Lin et al.   FREE RADICAL BIOLOGY AND MEDICINE

Intracellular labile iron

(2007) William Breuer et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY