Tumor Necrosis Factor Is a Therapeutic Target for Immunological Unbalance and Cardiac Abnormalities in Chronic Experimental Chagas’ Heart Disease

Severity of chronic experimental Chagas' heart disease parallels tumour necrosis factor and nitric oxide levels in the serum: models of mild and severe disease

(2014) Isabela Resende Pereira et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Plasma Cytokine Expression Is Associated with Cardiac Morbidity in Chagas Disease

(2014) Giovane Rodrigo Sousa et al.   PLoS One

Trypanosoma cruzi-induced depressive-like behavior is independent of meningoencephalitis but responsive to parasiticide and TNF-targeted therapeutic interventions

(2012) Glaucia Vilar-Pereira et al.   BRAIN BEHAVIOR AND IMMUNITY

In SituExpression of Regulatory Cytokines by Heart Inflammatory Cells in Chagas' Disease Patients with Heart Failure

(2012) Denise Bertulucci Rocha Rodrigues et al.   Clinical & Developmental Immunology

Levels of Circulating Th17 Cells and Regulatory T Cells in Ankylosing Spondylitis Patients with an Inadequate Response to Anti−TNF-α Therapy

(2012) Li Xueyi et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Inducible Nitric Oxide Synthase in Heart Tissue and Nitric Oxide in Serum of Trypanosoma cruzi-Infected Rhesus Monkeys: Association with Heart Injury

(2012) Cristiano Marcelo Espinola Carvalho et al.   PLoS Neglected Tropical Diseases

CD8+ T-Cells Expressing Interferon Gamma or Perforin Play Antagonistic Roles in Heart Injury in Experimental Trypanosoma Cruzi-Elicited Cardiomyopathy

(2012) Jaline Coutinho Silverio et al.   PLoS Pathogens

ECG scar quantification correlates with cardiac magnetic resonance scar size and prognostic factors in Chagas' disease

(2011) D. G. Strauss et al.   HEART

Functional Specialization of Interleukin-17 Family Members

(2011) Yoichiro Iwakura et al.   IMMUNITY

IL-10 Limits Parasite Burden and Protects against Fatal Myocarditis in a Mouse Model of Trypanosoma cruzi Infection

(2011) E. Roffe et al.   JOURNAL OF IMMUNOLOGY

Immunoneuroendocrine alterations in patients with progressive forms of chronic Chagas disease

(2011) A.R. Pérez et al.   JOURNAL OF NEUROIMMUNOLOGY

Tumor necrosis factor-alpha (TNF-α) is a therapeutic target for impaired cutaneous wound healing

(2011) Gillian S. Ashcroft et al.   WOUND REPAIR AND REGENERATION

Pharmacology of TNF blockade in rheumatoid arthritis and other chronic inflammatory diseases

(2010) Peter C Taylor   CURRENT OPINION IN PHARMACOLOGY

The endless race between Trypanosoma cruzi and host immunity: lessons for and beyond Chagas disease

(2010) Caroline Junqueira et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Chagas disease

(2010) Anis Rassi et al.   LANCET

IL-17 Produced during Trypanosoma cruzi Infection Plays a Central Role in Regulating Parasite-Induced Myocarditis

(2010) Paulo Marcos da Matta Guedes et al.   PLoS Neglected Tropical Diseases

Divergent Tumor Necrosis Factor Receptor–Related Remodeling Responses in Heart Failure

(2009) Tariq Hamid et al.   CIRCULATION

Short treatment with the tumour necrosis factor-α blocker infliximab diminishes chronic chagasic myocarditis in rats without evidence ofTrypanosoma cruzireactivation

(2009) A. R. Pérez et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Anti-TNF immunotherapy reduces CD8+ T cell–mediated antimicrobial activity against Mycobacterium tuberculosis in humans

(2009) Heiko Bruns et al.   JOURNAL OF CLINICAL INVESTIGATION

Development of chronic cardiomyopathy in canine Chagas disease correlates with high IFN-γ, TNF-α, and low IL-10 production during the acute infection phase

(2009) Paulo M.M. Guedes et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

TNF/TNFR1 signaling up-regulates CCR5 expression by CD8+ T lymphocytes and promotes heart tissue damage during Trypanosoma cruzi infection: beneficial effects of TNF-α blockade

(2008) Karina Kroll-Palhares et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Treatment of chronically Trypanosoma cruzi-infected mice with a CCR1/CCR5 antagonist (Met-RANTES) results in amelioration of cardiac tissue damage

(2008) Gabriela A. Medeiros et al.   MICROBES AND INFECTION

Strategy to Assess the Overall Cytokine Profile of Circulating Leukocytes and its Association with Distinct Clinical Forms of Human Chagas Disease

(2008) D. M. Vitelli-Avelar et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

TNFα blockade in human diseases: Mechanisms and future directions

(2007) Maida Wong et al.   CLINICAL IMMUNOLOGY