TRPs et al.: a molecular toolkit for thermosensory adaptations

Effects of cold temperatures on the excitability of rat trigeminal ganglion neurons that are not for cold sensing

(2017) Hirosato Kanda et al.   JOURNAL OF NEUROCHEMISTRY

K2P2.1 (TREK-1)–activator complexes reveal a cryptic selectivity filter binding site

(2017) Marco Lolicato et al.   NATURE

Activation of planarian TRPA1 by reactive oxygen species reveals a conserved mechanism for animal nociception

(2017) Oscar M. Arenas et al.   NATURE NEUROSCIENCE

TRPA1 expression levels and excitability brake by K V channels influence cold sensitivity of TRPA1-expressing neurons

(2017) Tosifa Memon et al.   NEUROSCIENCE

Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat

(2017) Thomas J. Park et al.   SCIENCE

Use Dependence of Heat Sensitivity of Vanilloid Receptor TRPV2

(2016) Beiying Liu et al.   BIOPHYSICAL JOURNAL

Evolution of Heat Sensors Drove Shifts in Thermosensation betweenXenopusSpecies Adapted to Different Thermal Niches

(2016) Shigeru Saito et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain

(2016) Jeremiah D. Osteen et al.   NATURE

The TRPM2 ion channel is required for sensitivity to warmth

(2016) Chun-Hsiang Tan et al.   NATURE

Low-cost functional plasticity of TRPV1 supports heat tolerance in squirrels and camels

(2016) Willem J. Laursen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Switch in Thermal Preference in Drosophila Larvae Depends on Multiple Rhodopsins

(2016) Takaaki Sokabe et al.   Cell Reports

Human TRPA1 is a heat sensor displaying intrinsic U-shaped thermosensitivity

(2016) Lavanya Moparthi et al.   Scientific Reports

Molecular biology of thermosensory transduction in C. elegans

(2015) Ichiro Aoki et al.   CURRENT OPINION IN NEUROBIOLOGY

NaV1.9: a sodium channel linked to human pain

(2015) Sulayman D. Dib-Hajj et al.   NATURE REVIEWS NEUROSCIENCE

Ion channels in nociceptors: Recent developments

(2015) E. E. Benarroch   NEUROLOGY

Painful peripheral neuropathy and sodium channel mutations

(2015) Janneke G.J. Hoeijmakers et al.   NEUROSCIENCE LETTERS

ThermoTRPs and Pain

(2015) Robyn J Laing et al.   NEUROSCIENTIST

Cold-aggravated pain in humans caused by a hyperactive NaV1.9 channel mutant

(2015) Enrico Leipold et al.   Nature Communications

The Nav1.9 Channel Is a Key Determinant of Cold Pain Sensation and Cold Allodynia

(2015) Stéphane Lolignier et al.   Cell Reports

TREK2 Expressed Selectively in IB4-Binding C-Fiber Nociceptors Hyperpolarizes Their Membrane Potentials and Limits Spontaneous Pain

(2014) C. Acosta et al.   JOURNAL OF NEUROSCIENCE

Painful and painless channelopathies

(2014) David L H Bennett et al.   LANCET NEUROLOGY

Heat and Noxious Chemical Sensor, Chicken TRPA1, as a Target of Bird Repellents and Identification of Its Structural Determinants by Multispecies Functional Comparison

(2014) Shigeru Saito et al.   MOLECULAR BIOLOGY AND EVOLUTION

Regulating excitability of peripheral afferents: emerging ion channel targets

(2014) Stephen G Waxman et al.   NATURE NEUROSCIENCE

Transmembrane Helix Straightening and Buckling Underlies Activation of Mechanosensitive and Thermosensitive K2P Channels

(2014) Marco Lolicato et al.   NEURON

Directionality of Temperature Activation in Mouse TRPA1 Ion Channel Can Be Inverted by Single-Point Mutations in Ankyrin Repeat Six

(2014) Sairam Jabba et al.   NEURON

Role of the TREK2 potassium channel in cold and warm thermosensation and in pain perception

(2014) Vanessa Pereira et al.   PAIN

Heat and AITC activate green anole TRPA1 in a membrane-delimited manner

(2014) Erkin Kurganov et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Down regulation of sodium channels in the central nervous system of hibernating snails

(2014) T. Kiss et al.   PHYSIOLOGY & BEHAVIOR

Human TRPA1 is intrinsically cold- and chemosensitive with and without its N-terminal ankyrin repeat domain

(2014) Lavanya Moparthi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ion Channel Profile of TRPM8 Cold Receptors Reveals a Role of TASK-3 Potassium Channels in Thermosensation

(2014) Cruz Morenilla-Palao et al.   Cell Reports

TRP Channels and Pain

(2013) David Julius   Annual Review of Cell and Developmental Biology

A Genetic Program Promotes C. elegans Longevity at Cold Temperatures via a Thermosensitive TRP Channel

(2013) Rui Xiao et al.   CELL

Hibernation

(2013) Fritz Geiser   CURRENT BIOLOGY

Ionotropic Receptors (IRs): Chemosensory ionotropic glutamate receptors in Drosophila and beyond

(2013) Raphael Rytz et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

The Cellular Code for Mammalian Thermosensation

(2013) L. A. Pogorzala et al.   JOURNAL OF NEUROSCIENCE

A Sensory-Labeled Line for Cold: TRPM8-Expressing Sensory Neurons Define the Cellular Basis for Cold, Cold Pain, and Cooling-Mediated Analgesia

(2013) W. M. Knowlton et al.   JOURNAL OF NEUROSCIENCE

The Zebrafish Ortholog of TRPV1 Is Required for Heat-Induced Locomotion

(2013) P. Gau et al.   JOURNAL OF NEUROSCIENCE

A gustatory receptor paralogue controls rapid warmth avoidance in Drosophila

(2013) Lina Ni et al.   NATURE

A de novo gain-of-function mutation in SCN11A causes loss of pain perception

(2013) Enrico Leipold et al.   NATURE GENETICS

Repeated functional convergent effects of NaV1.7 on acid insensitivity in hibernating mammals

(2013) Z. Liu et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Voltage-Gated Sodium Channel in Grasshopper Mice Defends Against Bark Scorpion Toxin

(2013) A. H. Rowe et al.   SCIENCE

Metabolic and thermal stimuli control K2P2.1 (TREK-1) through modular sensory and gating domains

(2012) Sviatoslav N Bagriantsev et al.   EMBO JOURNAL

Analysis of Transient Receptor Potential Ankyrin 1 (TRPA1) in Frogs and Lizards Illuminates Both Nociceptive Heat and Chemical Sensitivities and Coexpression with TRP Vanilloid 1 (TRPV1) in Ancestral Vertebrates

(2012) Shigeru Saito et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thermal sensitivity of voltage-gated Na+ channels and A-type K+ channels contributes to somatosensory neuron excitability at cooling temperatures

(2012) Ignacio Sarria et al.   JOURNAL OF NEUROCHEMISTRY

Current practices in a captive breeding colony of 13-lined ground squirrels (Ictidomys tridecemlineatus)

(2012) Dana K. Merriman et al.   LAB ANIMAL

Sensory Discrimination between Innocuous and Noxious Cold by TRPM8-Expressing DRG Neurons of Rats

(2012) Ignacio Sarria et al.   Molecular Pain

The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neurons

(2012) Hawon Cho et al.   NATURE NEUROSCIENCE

Correction: Dynamics of Mechanical Signal Transmission through Prestressed Stress Fibers

(2012) Yongyun Hwang et al.   PLoS One

Adaptive evolution of voltage-gated sodium channels: The first 800 million years

(2012) H. H. Zakon   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gain-of-function Nav1.8 mutations in painful neuropathy

(2012) C. G. Faber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA Editing Underlies Temperature Adaptation in K+ Channels from Polar Octopuses

(2012) S. Garrett et al.   SCIENCE

Structure and Hibernation-Associated Expression of the Transient Receptor Potential Vanilloid 4 Channel (TRPV4) mRNA in the Japanese Grass Lizard (Takydromus tachydromoides)

(2012) Kazuya Nagai et al.   ZOOLOGICAL SCIENCE

Thermosensory and Nonthermosensory Isoforms of Drosophila melanogaster TRPA1 Reveal Heat-Sensor Domains of a ThermoTRP Channel

(2012) Lixian Zhong et al.   Cell Reports

Multiple modalities converge on a common gate to control K2Pchannel function

(2011) Sviatoslav N Bagriantsev et al.   EMBO JOURNAL

Molecular Cloning and Functional Characterization ofXenopus tropicalisFrog Transient Receptor Potential Vanilloid 1 Reveal Its Functional Evolution for Heat, Acid, and Capsaicin Sensitivities in Terrestrial Vertebrates

(2011) Masashi Ohkita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Physiological adaptation of an Antarctic Na+/K+-ATPase to the cold

(2011) G. Galarza-Munoz et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Physiological interactions between Nav1.7 and Nav1.8 sodium channels: a computer simulation study

(2011) Jin-Sung Choi et al.   JOURNAL OF NEUROPHYSIOLOGY

Modulation of TRPA1 thermal sensitivity enables sensory discrimination in Drosophila

(2011) Kyeongjin Kang et al.   NATURE

Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats

(2011) Elena O. Gracheva et al.   NATURE

Temperature-dependent STIM1 activation induces Ca2+ influx and modulates gene expression

(2011) Bailong Xiao et al.   Nature Chemical Biology

TRPM3 Is a Nociceptor Channel Involved in the Detection of Noxious Heat

(2011) Joris Vriens et al.   NEURON

Functional Architecture of Olfactory Ionotropic Glutamate Receptors

(2011) Liliane Abuin et al.   NEURON

Transient receptor potential cation channel, subfamily C, member 5 (TRPC5) is a cold-transducer in the peripheral nervous system

(2011) K. Zimmermann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A thermodynamic framework for understanding temperature sensing by transient receptor potential (TRP) channels

(2011) D. E. Clapham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypermorphic mutation of the voltage-gated sodium channel encoding gene Scn10a causes a dramatic stimulus-dependent neurobehavioral phenotype

(2011) A. L. Blasius et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Function of Rhodopsin in Temperature Discrimination in Drosophila

(2011) W. L. Shen et al.   SCIENCE

The Molecular Basis of Acid Insensitivity in the African Naked Mole-Rat

(2011) E. S. J. Smith et al.   SCIENCE

TRPV1-lineage neurons are required for thermal sensation

(2010) Santosh K Mishra et al.   EMBO JOURNAL

TRPA1 Contributes to Cold Hypersensitivity

(2010) D. del Camino et al.   JOURNAL OF NEUROSCIENCE

Analysis of Drosophila TRPA1 reveals an ancient origin for human chemical nociception

(2010) Kyeongjin Kang et al.   NATURE

Molecular basis of infrared detection by snakes

(2010) Elena O. Gracheva et al.   NATURE

Specific roles for DEG/ENaC and TRP channels in touch and thermosensation in C. elegans nociceptors

(2010) Marios Chatzigeorgiou et al.   NATURE NEUROSCIENCE

TRPM8, but not TRPA1, is required for neural and behavioral responses to acute noxious cold temperatures and cold-mimetics in vivo

(2010) Wendy M. Knowlton et al.   PAIN

Molecular Background of Leak K+ Currents: Two-Pore Domain Potassium Channels

(2010) Péter Enyedi et al.   PHYSIOLOGICAL REVIEWS

The mechano-activated K+ channels TRAAK and TREK-1 control both warm and cold perception

(2009) Jacques Noël et al.   EMBO JOURNAL

Anopheles gambiaeTRPA1 is a heat-activated channel expressed in thermosensitive sensilla of female antennae

(2009) Guirong Wang et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Immunohistochemical colocalization of TREK-1, TREK-2 and TRAAK with TRP channels in the trigeminal ganglion cells

(2009) Yoshio Yamamoto et al.   NEUROSCIENCE LETTERS

Evolution of Thermal Response Properties in a Cold-Activated TRP Channel

(2009) Benjamin R. Myers et al.   PLoS One

Extracellular acidification exerts opposite actions on TREK1 and TREK2 potassium channels via a single conserved histidine residue

(2009) G. Sandoz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kv4 channels underlie the subthreshold-operating A-type K+-current in nociceptive dorsal root ganglion neurons

(2009) Thanawath Ratanadilok Na Phuket   Frontiers in Molecular Neuroscience

Drosophila Painless Is a Ca2+-Requiring Channel Activated by Noxious Heat

(2008) T. Sokabe et al.   JOURNAL OF NEUROSCIENCE

Pore region of TRPV3 ion channel is specifically required for heat activation

(2008) Jörg Grandl et al.   NATURE NEUROSCIENCE

Control of thermotactic behavior via coupling of a TRP channel to a phospholipase C signaling cascade

(2008) Young Kwon et al.   NATURE NEUROSCIENCE

Activation of transient receptor potential A1 channels by mustard oil, tetrahydrocannabinol and Ca2+ reveals different functional channel states

(2008) E.J. Cavanaugh et al.   NEUROSCIENCE