Multiple modalities converge on a common gate to control K2Pchannel function

Domain Reorientation and Rotation of an Intracellular Assembly Regulate Conduction in Kir Potassium Channels

(2010) Oliver B. Clarke et al.   CELL

SYMPOSIUM REVIEW: Gating of two pore domain potassium channels

(2010) Alistair Mathie et al.   JOURNAL OF PHYSIOLOGY-LONDON

The Membrane-Bound State of K2PPotassium Channels

(2010) Werner Treptow et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural mechanism of C-type inactivation in K+ channels

(2010) Luis G. Cuello et al.   NATURE

A dominant-negative mutation in the TRESK potassium channel is linked to familial migraine with aura

(2010) Ronald G Lafrenière et al.   NATURE MEDICINE

Temperature-induced opening of TRPV1 ion channel is stabilized by the pore domain

(2010) Jörg Grandl et al.   NATURE NEUROSCIENCE

Molecular Background of Leak K+ Currents: Two-Pore Domain Potassium Channels

(2010) Péter Enyedi et al.   PHYSIOLOGICAL REVIEWS

Conformational Changes During the Gating of a Potassium Channel Revealed by Structural Mass Spectrometry

(2010) Sayan Gupta et al.   STRUCTURE

The mechano-activated K+ channels TRAAK and TREK-1 control both warm and cold perception

(2009) Jacques Noël et al.   EMBO JOURNAL

Gating the pore of potassium leak channels

(2009) Asi Cohen et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

A structural model for K2Ppotassium channels based on 23 pairs of interacting sites and continuum electrostatics

(2009) Astrid Kollewe et al.   JOURNAL OF GENERAL PHYSIOLOGY

The response of the tandem pore potassium channel TASK-3 (K2P9.1) to voltage: gating at the cytoplasmic mouth

(2009) I. Ashmole et al.   JOURNAL OF PHYSIOLOGY-LONDON

Searching for interesting channels: pairing selection and molecular evolution methods to study ion channel structure and function

(2009) Daniel L. Minor et al.   Molecular BioSystems

Selection of Inhibitor-Resistant Viral Potassium Channels Identifies a Selectivity Filter Site that Affects Barium and Amantadine Block

(2009) Franck C. Chatelain et al.   PLoS One

Two amino acid residues determine 2-APB sensitivity of the ion channels TRPV3 and TRPV4

(2009) H. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extracellular acidification exerts opposite actions on TREK1 and TREK2 potassium channels via a single conserved histidine residue

(2009) G. Sandoz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Maternally Inherited Birk Barel Mental Retardation Dysmorphism Syndrome Caused by a Mutation in the Genomically Imprinted Potassium Channel KCNK9

(2008) Ortal Barel et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A Novel Mechanism for Human K2P2.1 Channel Gating

(2008) Asi Cohen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Biology of Background K Channels: Insights from K2P Knockout Mice

(2008) Marta Sabbadini et al.   JOURNAL OF MOLECULAR BIOLOGY

Pore region of TRPV3 ion channel is specifically required for heat activation

(2008) Jörg Grandl et al.   NATURE NEUROSCIENCE

Inverse coupling in leak and voltage-activated K+ channel gates underlies distinct roles in electrical signaling

(2008) Yuval Ben-Abu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Yeast Genetic Screen Reveals a Critical Role for the Pore Helix Domain in TRP Channel Gating

(2008) Benjamin R. Myers et al.   NEURON

Pharmacogenetic Analysis of Genes Implicated in Rodent Models of Antidepressant Response: Association of TREK1 and Treatment Resistance in the STAR*D Study

(2008) Roy H Perlis et al.   NEUROPSYCHOPHARMACOLOGY

Molecular basis of the mammalian pressure-sensitive ion channels: Focus on vascular mechanotransduction

(2008) Joost H.A. Folgering et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Emerging roles for two-pore-domain potassium channels and their potential therapeutic impact

(2008) Douglas A. Bayliss et al.   TRENDS IN PHARMACOLOGICAL SCIENCES