Synthesis, antimycobacterial activity, and acid dissociation constants of polyfunctionalized 3-[2-(pyrrolidin-1-yl)thiazole-5-carbonyl]-2H-chromen-2-one derivatives

Synthesis, antimicrobial activity and acid dissociation constants of methyl 5,5-diphenyl-1-(thiazol-2-yl)pyrrolidine-2-carboxylate derivatives

(2018) Yahya Nural et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Nickel(II) and copper(II) complexes of N,N -dialkyl- N ′-3-chlorobenzoylthiourea: Synthesis, characterization, crystal structures, Hirshfeld surfaces and antimicrobial activity

(2018) Gun Binzet et al.   JOURNAL OF MOLECULAR STRUCTURE

Hirshfeld surface analyses and crystal structures of supramolecular self-assembly thiourea derivatives directed by non-covalent interactions

(2018) Ilkay Gumus et al.   JOURNAL OF MOLECULAR STRUCTURE

Synthesis, crystal structure, DFT studies, acid dissociation constant, and antimicrobial activity of methyl 2-(4-chlorophenyl)-7a-((4-chlorophenyl)carbamothioyl)-1-oxo-5,5-diphenyl-3-thioxo-hexahydro-1H-pyrrolo[1,2-e]imidazole-6-carboxylate

(2018) Yahya Nural et al.   JOURNAL OF MOLECULAR STRUCTURE

New platinum (II) and palladium (II) complexes of coumarin-thiazole Schiff base with a fluorescent chemosensor properties: Synthesis, spectroscopic characterization, X-ray structure determination, in vitro anticancer activity on various human carcinoma cell lines and computational studies

(2018) Ömer Şahin et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Recent developments of coumarin-containing derivatives and their anti-tubercular activity

(2017) Yuan-Qiang Hu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Pt(II) and Ni(II) complexes of octahydropyrrolo[3,4-c]pyrrole N -benzoylthiourea derivatives: Synthesis, characterization, physical parameters and biological activity

(2017) Muge Gemili et al.   INORGANICA CHIMICA ACTA

Discovery of 4-((3′R,4′S,5′R)-6″-Chloro-4′-(3-chloro-2-fluorophenyl)-1′-ethyl-2″-oxodispiro[cyclohexane-1,2′-pyrrolidine-3′,3″-indoline]-5′-carboxamido)bicyclo[2.2.2]octane-1-carboxylic Acid (AA-115/APG-115): A Potent and Orally Active Murine Double Minute 2 (MDM2) Inhibitor in Clinical Development

(2017) Angelo Aguilar et al.   JOURNAL OF MEDICINAL CHEMISTRY

Coumarin-indole conjugate donor-acceptor system: Synthesis, photophysical properties, anion sensing ability, theoretical and biological activity studies of two coumarin-indole based push-pull dyes

(2017) Tuğçe Aksungur et al.   JOURNAL OF MOLECULAR STRUCTURE

Synthesis and anti(myco)bacterial activity of novel 5,5-diphenylpyrrolidine N-aroylthiourea derivatives and a functionalized hexahydro-1H-pyrrolo[1,2-c]imidazole

(2017) Duygu Erşen et al.   MEDICINAL CHEMISTRY RESEARCH

Synthesis and antimicrobial activity of bis(azolyl)quinazoline-2,4-diamines

(2017) Tamatam Rekha et al.   MONATSHEFTE FUR CHEMIE

The discovery of novel 5,6,5- and 5,5,6-tricyclic pyrrolidines as potent and selective DPP-4 inhibitors

(2016) Jason M. Cox et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis, antimycobacterial and antibacterial activity of 1-(6-amino-3,5-difluoropyridin-2-yl)fluoroquinolone derivatives containing an oxime functional moiety

(2016) Ju Huang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Determination and Validation of Capillary Electrophoretic and Liquid Chromatographic Methods for Concurrent Assay of Valganciclovir and Lamivudine in Pharmaceutical Formulations

(2016) Senem . Sanlı et al.   Current Pharmaceutical Analysis

Pyrrolidinone and pyrrolidine derivatives: Evaluation as inhibitors of InhA and Mycobacterium tuberculosis

(2016) Tetiana Matviiuk et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Therapeutic potential of coumarins as antiviral agents

(2016) Mohd. Zaheen Hassan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, crystal structure, anti-HIV, and antiproliferative activity of new oxadiazole and thiazole analogs

(2016) Mahmood-ul-Hassan Khan et al.   MEDICINAL CHEMISTRY RESEARCH

2,4-Disubstituted thiazoles as multitargated bioactive molecules

(2016) Preeti Arora et al.   MEDICINAL CHEMISTRY RESEARCH

Synthesis, anti-microbial activity, and cytotoxicity of novel 1-[5-[6-[(2-benzoylbenzofuran-5-yl)methyl]-2-oxo-2H-chromen-3-yl]thiazol-2-yl]urea derivatives

(2016) Bhookya Shankar et al.   MONATSHEFTE FUR CHEMIE

Synthesis and biological screening of a new series of 5-[4-(4-aryl-1-piperazinyl)butoxy]coumarins

(2016) Kinga Ostrowska et al.   MONATSHEFTE FUR CHEMIE

Solubility and acidic constants at 25 °C in NaClO4 aqueous solutions of 1-(2-hydroxyphenyl)ethanone

(2016) Emilia Furia et al.   MONATSHEFTE FUR CHEMIE

Substituent effects on ionization constants as a predictive tool of coordinating ability

(2016) Valeria M. Nurchi et al.   MONATSHEFTE FUR CHEMIE

Synthesis, antimycobacterial and antibacterial activity of l-[(1R,2S)-2-fluorocyclopropyl]naphthyridone derivatives containing an oxime-functionalized pyrrolidine moiety

(2015) Ju Huang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Coumarin: A Privileged Scaffold for the Design and Development of Antineurodegenerative Agents

(2015) Ehtesham Jameel et al.   Chemical Biology & Drug Design

Enantioselective formal synthesis of doxapram

(2015) Andrejs Krasikovs   Chemistry of Heterocyclic Compounds

Synthesis, antimycobacterial and antibacterial activity of fluoroquinolone derivatives containing an 3-alkoxyimino-4-(cyclopropylanimo)methylpyrrolidine moiety

(2015) Tingting Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Recent advances and therapeutic journey of coumarins: current status and perspectives

(2015) Kuldipsinh P. Barot et al.   MEDICINAL CHEMISTRY RESEARCH

A facile synthesis and evaluation of new biomolecule-based coumarin–thiazoline hybrids as potent anti-tubercular agents with cytotoxicity, DNA cleavage and X-ray studies

(2015) Dinesh S. Reddy et al.   RSC Advances

Catalytic Enantioselective 1,3-Dipolar Cycloadditions of Azomethine Ylides for Biology-Oriented Synthesis

(2014) Rishikesh Narayan et al.   ACCOUNTS OF CHEMICAL RESEARCH

Rationalization of the pKa Values of Alcohols and Thiols Using Atomic Charge Descriptors and Its Application to the Prediction of Amino Acid pKa’s

(2014) Ilke Ugur et al.   Journal of Chemical Information and Modeling

Synthesis of new naphthoisoxazole amide derivatives and study of their biological evaluations

(2014) Shubhangi S. Soman et al.   MEDICINAL CHEMISTRY RESEARCH

Synthesis, characterization, and pharmacological evaluation of some novel thiadiazoles and thiazoles incorporating pyrazole moiety as anticancer agents

(2014) Sobhi M. Gomha et al.   MONATSHEFTE FUR CHEMIE

Microwave-assisted preparation, structural characterization, lipophilicity, and anti-cancer assay of some hydroxycoumarin derivatives

(2014) Kinga Ostrowska et al.   MONATSHEFTE FUR CHEMIE

Synthesis, spectroscopic and structural characterization, and antimicrobial studies of metal complexes of a new hexadentate Schiff base ligand. Spectrophotometric determination of Fe(III) in water samples using a recovery test

(2014) Ehab M. Zayed et al.   MONATSHEFTE FUR CHEMIE

The effects of ionic strength and temperature on the dissociation constants of adefovir and cidofovir used as antiviral drugs

(2014) Hasan ATABEY et al.   TURKISH JOURNAL OF CHEMISTRY

Synthesis and biological evaluation of 2-aminothiazole derivatives as antimycobacterial and antiplasmodial agents

(2013) Faith Mjambili et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of γ,δ-Aziridino α-Amino Acid Derivatives and their Stereoselective Ring Transformation to 2-(Aminomethyl)-1-aminocyclopropanecarboxylic Acid Derivatives

(2013) Stijn De Brabandere et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Protonation Equilibria of Some Selected α-Amino Acids in DMSO–Water Mixture and Their Cu(II)-Complexes

(2013) Ahmed A. El-Sherif et al.   JOURNAL OF SOLUTION CHEMISTRY

Synthesis, X-ray crystallographic study, and biological evaluation of coumarin and quinolinone carboxamides as anticancer agents

(2013) Dimitris Matiadis et al.   MONATSHEFTE FUR CHEMIE

Novobiocin analogues with second-generation noviose surrogates

(2012) Huiping Zhao et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Protonation Equilibria of Carminic Acid and Stability Constants of Its Complexes with Some Divalent Metal Ions in Aqueous Solution

(2012) Hasan Atabey et al.   JOURNAL OF SOLUTION CHEMISTRY

Coumarinyl pyrazole derivatives of INH: promising antimycobacterial agents

(2012) Prashant Aragade et al.   MEDICINAL CHEMISTRY RESEARCH

A New Solvent System (Cyclopentyl Methyl Ether–Water) in Process Development of Darifenacin HBr

(2012) Chinmoy Pramanik et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Thiazoles: having diverse biological activities

(2011) Shiv Jee Kashyap et al.   MEDICINAL CHEMISTRY RESEARCH

Protolytic equilibria of picric acid in a mixture of protophobic and protophilic polar solvents non-donors of H-bonds

(2011) D. O. Ruzanov et al.   RUSSIAN JOURNAL OF GENERAL CHEMISTRY

Spectroscopic Determination and Evaluation of Acidity Constants for Some Drug Precursor 2-Amino-4-(3- or 4-substituted phenyl) Thiazole Derivatives

(2010) Cemil Öğretir et al.   JOURNAL OF CHEMICAL AND ENGINEERING DATA

pK a Determinations for Montelukast Sodium and Levodropropizine

(2010) Ibrahim Narin et al.   JOURNAL OF SOLUTION CHEMISTRY

Solvent effect on protonation constants of salicylic acid in mixed aqueous organic solutions of DMSO

(2010) Ali Farajtabar et al.   MONATSHEFTE FUR CHEMIE

Differential Involvement of P-Glycoprotein (ABCB1) in Permeability, Tissue Distribution, and Antinociceptive Activity of Methadone, Buprenorphine, and Diprenorphine: In Vitro and In Vivo Evaluation

(2009) Hazem E. Hassan et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

The acid–base profile of a contemporary set of drugs: implications for drug discovery

(2009) D.T. Manallack   SAR AND QSAR IN ENVIRONMENTAL RESEARCH

Determination of pK a values of clinically important perfluorochemicals in nonaqueous media

(2008) O. Hakli et al.   JOURNAL OF ANALYTICAL CHEMISTRY