Non-Metastatic Cutaneous Melanoma Induces Chronodisruption in Central and Peripheral Circadian Clocks

Melanopsin and rhodopsin mediate UVA-induced immediate pigment darkening: Unravelling the photosensitive system of the skin

(2018) Leonardo Vinícius Monteiro de Assis et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Exosomes derived from B16F0 melanoma cells alter the transcriptome of cytotoxic T cells that impacts mitochondrial respiration

(2018) Cassidy L. Bland et al.   FEBS Journal

Redox regulation of circadian molecular clock in chronic airway diseases

(2018) Isaac K. Sundar et al.   FREE RADICAL BIOLOGY AND MEDICINE

Melanocytes Sense Blue Light and Regulate Pigmentation through Opsin-3

(2018) Claire Regazzetti et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Circadian modification network of a core clock driver BMAL1 to harmonize physiology from brain to peripheral tissues

(2018) Teruya Tamaru et al.   NEUROCHEMISTRY INTERNATIONAL

The circadian clock regulates cisplatin-induced toxicity and tumor regression in melanoma mouse and human models

(2018) Panshak P. Dakup et al.   Oncotarget

The tumor circadian clock: a new target for cancer therapy?

(2017) Silke Kiessling et al.   Future Oncology

Circadian Clock, Cell Division, and Cancer: From Molecules to Organism

(2017) Anton Shostak   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A new path in defining light parameters for hair growth: Discovery and modulation of photoreceptors in human hair follicle

(2017) Serena Buscone et al.   LASERS IN SURGERY AND MEDICINE

Lipases and lipid droplet-associated protein expression in subcutaneous white adipose tissue of cachectic patients with cancer

(2017) Renata Silvério et al.   Lipids in Health and Disease

The circadian clock, metabolism and obesity

(2017) U. Albrecht   Obesity Reviews

Heat shock antagonizes UVA-induced responses in murine melanocytes and melanoma cells: an unexpected interaction

(2017) Leonardo Vinícius Monteiro de Assis et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Research progress on circadian clock genes in common abdominal malignant tumors (Review)

(2017) Sheng‑Li Yang et al.   Oncology Letters

Comprehensive analysis of normal adjacent to tumor transcriptomes

(2017) Dvir Aran et al.   Nature Communications

Remote reprogramming of hepatic circadian transcriptome by breast cancer

(2017) Hiroaki Hojo et al.   Oncotarget

Desynchronization of Circadian Clocks in Cancer: A Metabolic and Epigenetic Connection

(2017) Kiran Padmanabhan et al.   Frontiers in Endocrinology

Melanopsin, a Canonical Light Receptor, Mediates Thermal Activation of Clock Genes

(2017) Maria Nathália Moraes et al.   Scientific Reports

The effect of white light on normal and malignant murine melanocytes: A link between opsins, clock genes, and melanogenesis

(2016) L.V.M. de Assis et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Advances in immunotherapy for melanoma

(2016) Jason M. Redman et al.   BMC Medicine

Circadian Homeostasis of Liver Metabolism Suppresses Hepatocarcinogenesis

(2016) Nicole M. Kettner et al.   CANCER CELL

Tumor microenvironment and cancer therapy resistance

(2016) Yu Sun   CANCER LETTERS

Lung Adenocarcinoma Distally Rewires Hepatic Circadian Homeostasis

(2016) Selma Masri et al.   CELL

Circadian Rhythm Disruption Promotes Lung Tumorigenesis

(2016) Thales Papagiannakopoulos et al.   Cell Metabolism

The Circadian Clock and Human Health

(2016) Till Roenneberg et al.   CURRENT BIOLOGY

Impact of the physical microenvironment on tumor progression and metastasis

(2016) Fabian Spill et al.   CURRENT OPINION IN BIOTECHNOLOGY

Circadian Rhythm and Sleep Disruption: Causes, Metabolic Consequences, and Countermeasures

(2016) Gregory D. M. Potter et al.   ENDOCRINE REVIEWS

Daily Fasting Blood Glucose Rhythm in Male Mice: A Role of the Circadian Clock in the Liver

(2016) Hitoshi Ando et al.   ENDOCRINOLOGY

Endocrine regulation of circadian physiology

(2016) Anthony H Tsang et al.   JOURNAL OF ENDOCRINOLOGY

Estradiol differently affects melanin synthesis of malignant and normal melanocytes: a relationship with clock and clock-controlled genes

(2016) Maristela Oliveira Poletini et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Transcriptional architecture of the mammalian circadian clock

(2016) Joseph S. Takahashi   NATURE REVIEWS GENETICS

Impact of the Circadian Clock on UV-Induced DNA Damage Response and Photocarcinogenesis

(2016) Panshak Dakup et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Altered circadian clock gene expression in patients with schizophrenia

(2016) Anne-Sofie Johansson et al.   SCHIZOPHRENIA RESEARCH

Circadian time signatures of fitness and disease

(2016) Joseph Bass et al.   SCIENCE

Circadian Metabolism: From Mechanisms to Metabolomics and Medicine

(2016) Steven A. Brown   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Melanin content in melanoma metastases affects the outcome of radiotherapy

(2016) Anna A. Brożyna et al.   Oncotarget

The cost of circadian desynchrony: Evidence, insights and open questions

(2015) Alexander C. West et al.   BIOESSAYS

Synchronization of the mammalian circadian timing system: Light can control peripheral clocks independently of the SCN clock

(2015) Jana Husse et al.   BIOESSAYS

Genomic Classification of Cutaneous Melanoma

(2015) Rehan Akbani et al.   CELL

Overall survival in patients with metastatic melanoma

(2015) Xue Song et al.   CURRENT MEDICAL RESEARCH AND OPINION

Circadian clocks, epigenetics, and cancer

(2015) Selma Masri et al.   CURRENT OPINION IN ONCOLOGY

Circadian Metabolism in the Light of Evolution

(2015) Zachary Gerhart-Hines et al.   ENDOCRINE REVIEWS

Circadian Clocks in the Immune System

(2015) Nathalie Labrecque et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Molecular mechanism of PPARα action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease

(2015) Michal Pawlak et al.   JOURNAL OF HEPATOLOGY

When the Circadian Clock Meets the Melanin Pigmentary System

(2015) Andrzej T. Slominski et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Peripheral Clock Regulates Human Pigmentation

(2015) Jonathan A. Hardman et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

(2015) et al.   SCIENCE

The role of MEK inhibitors in the treatment of metastatic melanoma

(2014) Antonio M. Grimaldi et al.   CURRENT OPINION IN ONCOLOGY

The light-dark cycle controls peripheral rhythmicity in mice with a genetically ablated suprachiasmatic nucleus clock

(2014) Jana Husse et al.   FASEB JOURNAL

The circadian clock regulates rhythmic activation of the NRF2/glutathione-mediated antioxidant defense pathway to modulate pulmonary fibrosis

(2014) V. Pekovic-Vaughan et al.   GENES & DEVELOPMENT

Local Melatoninergic System as the Protector of Skin Integrity

(2014) Andrzej Slominski et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Circadian clock control of endocrine factors

(2014) Karen L. Gamble et al.   Nature Reviews Endocrinology

Combined BRAF and MEK Inhibition versus BRAF Inhibition Alone in Melanoma

(2014) Georgina V. Long et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tumor Macroenvironment and Metabolism

(2014) Wael Al-Zhoughbi et al.   SEMINARS IN ONCOLOGY

Differential effects of light and feeding on circadian organization of peripheral clocks in a forebrain Bmal1 mutant

(2014) Mariko Izumo et al.   eLife

Oxidative Stress and Inflammation Modulate Rev-erbα Signaling in the Neonatal Lung and Affect Circadian Rhythmicity

(2013) Guang Yang et al.   ANTIOXIDANTS & REDOX SIGNALING

Targeting the Tumor Microenvironment: From Understanding Pathways to Effective Clinical Trials

(2013) H. Fang et al.   CANCER RESEARCH

Melanogenesis affects overall and disease-free survival in patients with stage III and IV melanoma

(2013) Anna A. Brożyna et al.   HUMAN PATHOLOGY

Chronobiology of Melatonin beyond the Feedback to the Suprachiasmatic Nucleus—Consequences to Melatonin Dysfunction

(2013) Rüdiger Hardeland   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The tumor microenvironment at a glance

(2013) F. R. Balkwill et al.   JOURNAL OF CELL SCIENCE

Violet Light Down-Regulates the Expression of Specific Differentiation Markers through Rhodopsin in Normal Human Epidermal Keratinocytes

(2013) Hyoung-June Kim et al.   PLoS One

Opsin3 sensitizes hepatocellular carcinoma cells to 5-fluorouracil treatment by regulating the apoptotic pathway

(2012) Jianhua Jiao et al.   CANCER LETTERS

Rev-erb  and Rev-erb  coordinately protect the circadian clock and normal metabolic function

(2012) A. Bugge et al.   GENES & DEVELOPMENT

Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β

(2012) Han Cho et al.   NATURE

Altered expression patterns of clock gene mRNAs and clock proteins in human skin tumors

(2012) Zsuzsanna Lengyel et al.   TUMOR BIOLOGY

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

UVA Phototransduction Drives Early Melanin Synthesis in Human Melanocytes

(2011) Nadine L. Wicks et al.   CURRENT BIOLOGY

Synaptotagmin10-Cre, a Driver to Disrupt Clock Genes in the SCN

(2011) Jana Husse et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation

(2011) Paul B. Chapman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Deficient of a Clock Gene, Brain and Muscle Arnt-Like Protein-1 (BMAL1), Induces Dyslipidemia and Ectopic Fat Formation

(2011) Shigeki Shimba et al.   PLoS One

Control of skin cancer by the circadian rhythm

(2011) S. Gaddameedhi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Suprachiasmatic Nucleus: Cell Autonomy and Network Properties

(2010) David K. Welsh et al.   Annual Review of Physiology

The Mammalian Circadian Timing System: Organization and Coordination of Central and Peripheral Clocks

(2010) Charna Dibner et al.   Annual Review of Physiology

PER2 Controls Lipid Metabolism by Direct Regulation of PPARγ

(2010) Benedetto Grimaldi et al.   Cell Metabolism

Tumors as Organs: Complex Tissues that Interface with the Entire Organism

(2010) Mikala Egeblad et al.   DEVELOPMENTAL CELL

Physiology of Circadian Entrainment

(2010) Diego A. Golombek et al.   PHYSIOLOGICAL REVIEWS

Decoding Melanoma Metastasis

(2010) William E. Damsky et al.   Cancers

GLUT2 mutations, translocation, and receptor function in diet sugar managing

(2009) Armelle Leturque et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Epidemiology of invasive cutaneous melanoma

(2009) R. M. MacKie et al.   ANNALS OF ONCOLOGY

The Classification of Cutaneous Melanoma

(2009) Lyn McDivitt Duncan   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Bile acids: regulation of synthesis

(2009) John Y. L. Chiang   JOURNAL OF LIPID RESEARCH

TRPM1 Forms Ion Channels Associated with Melanin Content in Melanocytes

(2009) E. Oancea et al.   Science Signaling

Clock genes, intestinal transport and plasma lipid homeostasis

(2009) M. Mahmood Hussain et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Cancer Statistics, 2008

(2008) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Inhibition of melanogenesis as a radiation sensitizer for melanoma therapy

(2008) Anna A. Brożyna et al.   INTERNATIONAL JOURNAL OF CANCER

The Critical Role of PPARγin Human Malignant Melanoma

(2008) Christian Freudlsperger et al.   PPAR Research