Chronobiology of Melatonin beyond the Feedback to the Suprachiasmatic Nucleus—Consequences to Melatonin Dysfunction

Chronic mild stress alters circadian expressions of molecular clock genes in the liver

(2012) Kei Takahashi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Rhythmic expression of circadian clock genes in human leukocytes and beard hair follicle cells

(2012) Makiko Watanabe et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

DNA Microarray Analysis and Functional Profile of Pituitary Transcriptome Under Core-Clock Protein BMAL1 Control

(2012) F. Guillaumond et al.   CHRONOBIOLOGY INTERNATIONAL

Differential Patterns in the Periodicity and Dynamics of Clock Gene Expression in Mouse Liver and Stomach

(2012) Gianluigi Mazzoccoli et al.   CHRONOBIOLOGY INTERNATIONAL

Tired of Diabetes Genetics? Circadian Rhythms and Diabetes: The MTNR1B Story?

(2012) Cecilia Nagorny et al.   Current Diabetes Reports

Simulated body temperature rhythms reveal the phase-shifting behavior and plasticity of mammalian circadian oscillators

(2012) C. Saini et al.   GENES & DEVELOPMENT

Genetic and functional abnormalities of the melatonin biosynthesis pathway in patients with bipolar disorder

(2012) Bruno Etain et al.   HUMAN MOLECULAR GENETICS

Melatonin pathway genes are associated with progressive subtypes and disability status in multiple sclerosis among Finnish patients

(2012) Renuka Natarajan et al.   JOURNAL OF NEUROIMMUNOLOGY

Crystal structure and functional mapping of human ASMT, the last enzyme of the melatonin synthesis pathway

(2012) Hany Goubran Botros et al.   JOURNAL OF PINEAL RESEARCH

Circadian rhythms govern cardiac repolarization and arrhythmogenesis

(2012) Darwin Jeyaraj et al.   NATURE

Rare MTNR1B variants impairing melatonin receptor 1B function contribute to type 2 diabetes

(2012) Amélie Bonnefond et al.   NATURE GENETICS

A Dual-Color Luciferase Assay System Reveals Circadian Resetting of Cultured Fibroblasts by Co-Cultured Adrenal Glands

(2012) Takako Noguchi et al.   PLoS One

Divergent Roles of Clock Genes in Retinal and Suprachiasmatic Nucleus Circadian Oscillators

(2012) Guo-Xiang Ruan et al.   PLoS One

Neurobiology, Pathophysiology, and Treatment of Melatonin Deficiency and Dysfunction

(2012) Rüdiger Hardeland   TheScientificWorldJOURNAL

Adrenal peripheral oscillator in generating the circadian glucocorticoid rhythm

(2011) Sooyoung Chung et al.   Annals of the New York Academy of Sciences

Circadian rhythm of adrenal glucocorticoid: Its regulation and clinical implications

(2011) Sooyoung Chung et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Tissue-Dependent Alterations of the Clock Gene Expression Rhythms in Leptin-Resistant Zucker Diabetic Fatty Rats

(2011) Yuya Motosugi et al.   CHRONOBIOLOGY INTERNATIONAL

The adrenal peripheral clock: Glucocorticoid and the circadian timing system

(2011) Gi Hoon Son et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Melatonin Receptor 1A Gene Polymorphism Associated with Polycystic Ovary Syndrome

(2011) Chao Li et al.   GYNECOLOGIC AND OBSTETRIC INVESTIGATION

Association of Polymorphism in the Promoter of the Melatonin Receptor 1A Gene with Schizophrenia and with Insomnia Symptoms in Schizophrenia Patients

(2011) Hae Jeong Park et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

A case-control study of melatonin receptor type 1A polymorphism and acute myocardial infarction in a Spanish population

(2011) Sima Samimi-Fard et al.   JOURNAL OF PINEAL RESEARCH

Genetic variations of the melatonin pathway in patients with attention-deficit and hyperactivity disorders

(2011) Pauline Chaste et al.   JOURNAL OF PINEAL RESEARCH

Melatonin, the circadian multioscillator system and health: the need for detailed analyses of peripheral melatonin signaling

(2011) Rüdiger Hardeland et al.   JOURNAL OF PINEAL RESEARCH

The melatonin receptor 1A (MTNR1A) gene is associated with recurrent and idiopathic calcium nephrolithiasis

(2011) Teresa Esposito et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Association Study of BMP4, IL6, Leptin, MMP3, and MTNR1B Gene Promoter Polymorphisms and Adolescent Idiopathic Scoliosis

(2011) Mónika Mórocz et al.   SPINE

Combination of starvation interval and food volume determines the phase of liver circadian rhythm in Per2::Luc knock-in mice under two meals per day feeding

(2010) Akiko Hirao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Mutation screening of melatonin-related genes in patients with autism spectrum disorders

(2010) Lina Jonsson et al.   BMC Medical Genomics

Multiscale complexity in the mammalian circadian clock

(2010) YR Yamada et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Investigational melatonin receptor agonists

(2010) Rüdiger Hardeland   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Adrenal glucocorticoids have a key role in circadian resynchronization in a mouse model of jet lag

(2010) Silke Kiessling et al.   JOURNAL OF CLINICAL INVESTIGATION

Melatonin in septic shock: Some recent concepts

(2010) Venkataramanujan Srinivasan et al.   JOURNAL OF CRITICAL CARE

Single-nucleotide polymorphisms and mRNA expression for melatonin synthesis rate-limiting enzyme in recurrent depressive disorder

(2010) Piotr Gałecki et al.   JOURNAL OF PINEAL RESEARCH

Melatonin receptor 1-dependent gene expression in the mouse pars tuberalis as revealed by cDNA microarray analysis andin situhybridization

(2010) Claudia Unfried et al.   JOURNAL OF PINEAL RESEARCH

Association of rs10830963 and rs10830962 SNPs in the melatonin receptor (MTNR1B) gene among Han Chinese women with polycystic ovary syndrome

(2010) C. Li et al.   MOLECULAR HUMAN REPRODUCTION

Clocks not winding down: unravelling circadian networks

(2010) Eric E. Zhang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Comparison between Circadian Oscillators in Mouse Liver and Pituitary Gland Reveals Different Integration of Feeding and Light Schedules

(2010) Isabelle M. Bur et al.   PLoS One

Noninvasive method for assessing the human circadian clock using hair follicle cells

(2010) M. Akashi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Melatonin—A pleiotropic, orchestrating regulator molecule

(2010) Rüdiger Hardeland et al.   PROGRESS IN NEUROBIOLOGY

Temperature as a Universal Resetting Cue for Mammalian Circadian Oscillators

(2010) E. D. Buhr et al.   SCIENCE

Circadian Integration of Metabolism and Energetics

(2010) J. Bass et al.   SCIENCE

New approaches in the management of insomnia: weighing the advantages of prolonged-release melatonin and synthetic melatoninergic agonists

(2010) Ruediger Hardeland   Neuropsychiatric Disease and Treatment

Melatonin and tryptophan circadian profiles in patients with advanced non-small cell lung cancer

(2009) Shilian Hu et al.   ADVANCES IN THERAPY

Circadian temperature variation and ageing

(2009) Dietmar Weinert   AGEING RESEARCH REVIEWS

Melatonin: Signaling mechanisms of a pleiotropic agent

(2009) Rüdiger Hardeland   BIOFACTORS

Obesity alters circadian expressions of molecular clock genes in the brainstem

(2009) Keizo Kaneko et al.   BRAIN RESEARCH

A Genome-wide RNAi Screen for Modifiers of the Circadian Clock in Human Cells

(2009) Eric E. Zhang et al.   CELL

Differential Effects of a Restricted Feeding Schedule on Clock-Gene Expression in the Hypothalamus of the Rat

(2009) M. C. Miñana-Solis et al.   CHRONOBIOLOGY INTERNATIONAL

Clinical Aspects of Melatonin in the Acute Coronary Syndrome

(2009) Alberto Dominguez-Rodriguez et al.   Current Vascular Pharmacology

The SCN-independent clocks, methamphetamine and food restriction

(2009) Ken-ichi Honma et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Loss of melatonin signalling and its impact on circadian rhythms in mouse organs regulating blood glucose

(2009) Eckhard Mühlbauer et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Melatonin and Melatonergic Drugs on Sleep: Possible Mechanisms of Action

(2009) Venkataramanujan Srinivasan et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Abnormal expressions of circadian-clock and circadian clock-controlled genes in the livers and kidneys of long-term, high-fat-diet-treated mice

(2009) M-C Hsieh et al.   INTERNATIONAL JOURNAL OF OBESITY

Circadian Rhythm of Clock Genes in Human Adipose Explants

(2009) Cecilia Gómez-Santos et al.   Obesity

Daily Electrical Silencing in the Mammalian Circadian Clock

(2009) M. D. C. Belle et al.   SCIENCE

The circadian clock system in the mammalian retina

(2008) Gianluca Tosini et al.   BIOESSAYS

GPR50 is the mammalian ortholog of Mel1c: Evidence of rapid evolution in mammals

(2008) Laurence Dufourny et al.   BMC EVOLUTIONARY BIOLOGY

Circadian mechanisms in murine and human bone marrow mesenchymal stem cells following dexamethasone exposure

(2008) Xiying Wu et al.   BONE

Melatonin, hormone of darkness and more – occurrence, control mechanisms, actions and bioactive metabolites

(2008) R. Hardeland   CELLULAR AND MOLECULAR LIFE SCIENCES

Melatonin Receptor Agonists: SAR and Applications to the Treatment of Sleep-Wake Disorders

(2008) Silvia Rivara et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Circadian Timing in the Lung; A Specific Role for Bronchiolar Epithelial Cells

(2008) J. E. Gibbs et al.   ENDOCRINOLOGY

Dopamine modulates diurnal and circadian rhythms of protein phosphorylation in photoreceptor cells of mouse retina

(2008) Nikita Pozdeyev et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Effects of light cues on re-entrainment of the food-dominated peripheral clocks in mammals

(2008) Tao Wu et al.   GENE

Molecular Clocks in Mouse Skin

(2008) Miki Tanioka et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The role of the thalamus in sleep, pineal melatonin production, and circadian rhythm sleep disorders

(2008) James E. Jan et al.   JOURNAL OF PINEAL RESEARCH

The melatonin receptor MT1 is required for the differential regulatory actions of melatonin on neuronal ‘clock’ gene expression in striatal neurons in vitro

(2008) Marta Imbesi et al.   JOURNAL OF PINEAL RESEARCH

Melatonin and the Immune System in Aging

(2008) Daniel P. Cardinali et al.   NEUROIMMUNOMODULATION

Physiological significance of a peripheral tissue circadian clock

(2008) K. A. Lamia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The association of nocturnal serum melatonin levels with major depression in patients with acute multiple sclerosis

(2008) Zehra Akpınar et al.   PSYCHIATRY RESEARCH

An Autonomous Circadian Clock in the Inner Mouse Retina Regulated by Dopamine and GABA

(2008) Guo-Xiang Ruan et al.   PLOS BIOLOGY

A three pulse phase response curve to three milligrams of melatonin in humans

(2007) Helen J. Burgess et al.   JOURNAL OF PHYSIOLOGY-LONDON