Casein kinase 1α: biological mechanisms and theranostic potential

CK1α overexpression correlates with poor survival in colorectal cancer

(2018) Julia Richter et al.   BMC CANCER

Endo-lysosomal dysfunction: a converging mechanism in neurodegenerative diseases

(2018) Chao Wang et al.   CURRENT OPINION IN NEUROBIOLOGY

CK1α suppresses lung tumour growth by stabilizing PTEN and inducing autophagy

(2018) Junchao Cai et al.   NATURE CELL BIOLOGY

Novel Serine 176 Phosphorylation of YBX1 Activates NF-κB in Colon Cancer

(2017) Matthew Martin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of protein kinases CK1α and CK2 in multiple myeloma: regulation of pivotal survival and stress-managing pathways

(2017) Sabrina Manni et al.   Journal of Hematology & Oncology

An Argonaute phosphorylation cycle promotes microRNA-mediated silencing

(2017) Ryan J. Golden et al.   NATURE

Genetic effects on gene expression across human tissues

(2017) François Aguet et al.   NATURE

Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles

(2017) Lorenzo Galluzzi et al.   NATURE REVIEWS DRUG DISCOVERY

Trends in GPCR drug discovery: new agents, targets and indications

(2017) Alexander S. Hauser et al.   NATURE REVIEWS DRUG DISCOVERY

Amyloid-β and tau complexity — towards improved biomarkers and targeted therapies

(2017) Juan Carlos Polanco et al.   Nature Reviews Neurology

Not just amyloid: physiological functions of the amyloid precursor protein family

(2017) Ulrike C. Müller et al.   NATURE REVIEWS NEUROSCIENCE

CK1α ablation in keratinocytes induces p53-dependent, sunburn-protective skin hyperpigmentation

(2017) Chung-Hsing Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

p97/VCP promotes degradation of CRBN substrate glutamine synthetase and neosubstrates

(2017) Thang Van Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The down-regulation of casein kinase 1 alpha as a host defense response against infectious bursal disease virus infection

(2017) Lizhou Zhang et al.   VIROLOGY

Inactivation of CK1α in multiple myeloma empowers drug cytotoxicity by affecting AKT and β-catenin survival signaling pathways

(2017) Sabrina Manni et al.   Oncotarget

Identification of modulators of autophagic flux in an image-based high content siRNA screen

(2016) Christopher M. Hale et al.   Autophagy

HSF1 stress response pathway regulates autophagy receptor SQSTM1/p62-associated proteostasis

(2016) Yoshihisa Watanabe et al.   Autophagy

Casein kinase 1α has a non-redundant and dominant role within the CK1 family in melanoma progression

(2016) Tobias Sinnberg et al.   BMC CANCER

Expression of circadian clock genes and proteins in urothelial cancer is related to cancer-associated genes

(2016) Jorunn Litlekalsoy et al.   BMC CANCER

Jade-1S phosphorylation induced by CK1α contributes to cell cycle progression

(2016) Lori Borgal et al.   CELL CYCLE

Targeted disruption of CK1α in Toxoplasma gondii increases acute virulence in mice

(2016) Zedong Wang et al.   EUROPEAN JOURNAL OF PROTISTOLOGY

The molecular mechanism of thalidomide analogs in hematologic malignancies

(2016) Stefanie Lindner et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Defeating Alzheimer's disease and other dementias: a priority for European science and society

(2016) Bengt Winblad et al.   LANCET NEUROLOGY

Type I Interferons Control Proliferation and Function of the Intestinal Epithelium

(2016) Yuliya V. Katlinskaya et al.   MOLECULAR AND CELLULAR BIOLOGY

Defining the clonal dynamics leading to mouse skin tumour initiation

(2016) Adriana Sánchez-Danés et al.   NATURE

The road to restoring neural circuits for the treatment of Alzheimer's disease

(2016) Rebecca G. Canter et al.   NATURE

Structural basis of lenalidomide-induced CK1α degradation by the CRL4CRBN ubiquitin ligase

(2016) Georg Petzold et al.   NATURE

Nuclear GSK3β promotes tumorigenesis by phosphorylating KDM1A and inducing its deubiquitylation by USP22

(2016) Aidong Zhou et al.   NATURE CELL BIOLOGY

Identification of a Tumor Specific, Active-Site Mutation in Casein Kinase 1α by Chemical Proteomics

(2016) Eric S. Okerberg et al.   PLoS One

Secondary interaction between MDMX and p53 core domain inhibits p53 DNA binding

(2016) Xi Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct Signaling Requirements for the Establishment of ESC Pluripotency in Late-Stage EpiSCs

(2016) Damir Jacob Illich et al.   Cell Reports

The interplay between HPIP and casein kinase 1α promotes renal cell carcinoma growth and metastasis via activation of mTOR pathway

(2016) H Mai et al.   Oncogenesis

Targeting miR-155 to Treat Experimental Scleroderma

(2016) Qingran Yan et al.   Scientific Reports

Casein kinase 1 is recruited to nuclear speckles by FAM83H and SON

(2016) Takahisa Kuga et al.   Scientific Reports

HDAC6 Inhibitors Modulate Lys49 Acetylation and Membrane Localization of β-Catenin in Human iPSC-Derived Neuronal Cells

(2015) Jonathan Iaconelli et al.   ACS Chemical Biology

CSNK1A1mutations and gene expression analysis in myelodysplastic syndromes with del(5q)

(2015) Erica Bello et al.   BRITISH JOURNAL OF HAEMATOLOGY

Inhibition of Casein Kinase 1 Alpha Prevents Acquired Drug Resistance to Erlotinib in EGFR-Mutant Non-Small Cell Lung Cancer

(2015) A. B. Lantermann et al.   CANCER RESEARCH

Casein kinase 1 (α, δ and ε) localize at the spindle poles, but may not be essential for mammalian oocyte meiotic progression

(2015) Shu-Tao Qi et al.   CELL CYCLE

Genome-wide analysis identifies a role for common copy number variants in specific language impairment

(2015) Nuala H Simpson et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Pharmacological inhibition of ULK1 kinase blocks mammalian target of rapamycin (mTOR)-dependent autophagy.

(2015) Katy J. Petherick et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of Novel Serine 316 Phosphorylation of the p65 Subunit of NF-κB in Differential Gene Regulation

(2015) Benlian Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Parkinson Disease Mutant E46K Enhances α-Synuclein Phosphorylation in Mammalian Cell Lines, in Yeast, andin Vivo

(2015) Martial Kamdem Mbefo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Casein kinase 1α–dependent feedback loop controls autophagy in RAS-driven cancers

(2015) Jit Kong Cheong et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeting α-synuclein for treatment of Parkinson's disease: mechanistic and therapeutic considerations

(2015) Benjamin Dehay et al.   LANCET NEUROLOGY

Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS

(2015) Jan Krönke et al.   NATURE

Integrated molecular analysis of adult T cell leukemia/lymphoma

(2015) Keisuke Kataoka et al.   NATURE GENETICS

Phosphorylation regulates the Star-PAP-PIPKIα interaction and directs specificity toward mRNA targets

(2015) Nimmy Mohan et al.   NUCLEIC ACIDS RESEARCH

Mechanical strain induces E-cadherin-dependent Yap1 and  -catenin activation to drive cell cycle entry

(2015) B. W. Benham-Pyle et al.   SCIENCE

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

Phosphorylation of FADD by the kinase CK1α promotes KRASG12D-induced lung cancer

(2015) Brittany M. Bowman et al.   Science Signaling

Drosophila glucome screening identifies Ck1alpha as a regulator of mammalian glucose metabolism

(2015) Rupali Ugrankar et al.   Nature Communications

Drosophila Casein Kinase I Alpha Regulates Homolog Pairing and Genome Organization by Modulating Condensin II Subunit Cap-H2 Levels

(2015) Huy Q. Nguyen et al.   PLoS Genetics

Phosphorylation of FADD by the kinase CK1α promotes KRASG12D-induced lung cancer

(2015) Brittany M. Bowman et al.   Science Signaling

CSNK1A1 mutations and isolated del(5q) abnormality in myelodysplastic syndrome: a retrospective mutational analysis

(2015) Alexander E Smith et al.   Lancet Haematology

Role of Casein Kinase 1A1 in the Biology and Targeted Therapy of del(5q) MDS

(2014) Rebekka K. Schneider et al.   CANCER CELL

Pyrvinium Attenuates Hedgehog Signaling Downstream of Smoothened

(2014) Bin Li et al.   CANCER RESEARCH

Ultraviolet radiation-induced inflammation activates β-catenin signaling in mouse skin and skin tumors

(2014) RAM PRASAD et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Casein Kinase 1 α Phosphorylates the Wnt Regulator Jade-1 and Modulates Its Activity

(2014) Lori Borgal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Slowing of neurodegeneration in Parkinson's disease and Huntington's disease: future therapeutic perspectives

(2014) Anthony H V Schapira et al.   LANCET

CSNK1α1 mediates malignant plasma cell survival

(2014) Y Hu et al.   LEUKEMIA

Alleviation of Behavioral Hypersensitivity in Mouse Models of Inflammatory Pain with Two Structurally Different Casein Kinase 1 (CK1) Inhibitors

(2014) Takashi Kurihara et al.   Molecular Pain

Wnt signaling controls the specification of definitive and primitive hematopoiesis from human pluripotent stem cells

(2014) Christopher M Sturgeon et al.   NATURE BIOTECHNOLOGY

Can we safely target the WNT pathway?

(2014) Michael Kahn   NATURE REVIEWS DRUG DISCOVERY

Repurposing the FDA-Approved Pinworm Drug Pyrvinium as a Novel Chemotherapeutic Agent for Intestinal Polyposis

(2014) Bin Li et al.   PLoS One

FOXO transcription factors: key regulators of cellular quality control

(2014) Ashley E. Webb et al.   TRENDS IN BIOCHEMICAL SCIENCES

Phosphorylation of LRRK2 by casein kinase 1α regulates trans-Golgi clustering via differential interaction with ARHGEF7

(2014) Ruth Chia et al.   Nature Communications

Pyrvinium pamoate does not activate protein kinase CK1, but promotes Akt/PKB down-regulation and GSK3 activation

(2013) Andrea Venerando et al.   BIOCHEMICAL JOURNAL

The Wnt signalling pathway is upregulated in an in vitro model of acquired tamoxifen resistant breast cancer

(2013) Yan Ni Loh et al.   BMC CANCER

Integral analysis of p53 and its value as prognostic factor in sporadic colon cancer

(2013) Arantza Fariña Sarasqueta et al.   BMC CANCER

A Senescence-Inflammatory Switch from Cancer-Inhibitory to Cancer-Promoting Mechanism

(2013) Ariel Pribluda et al.   CANCER CELL

Altered vascular activation due to deficiency of the NADPH oxidase component p22phox

(2013) He Wang et al.   CARDIOVASCULAR PATHOLOGY

Targeting Placental Growth Factor/Neuropilin 1 Pathway Inhibits Growth and Spread of Medulloblastoma

(2013) Matija Snuderl et al.   CELL

Differential Regulation of Distinct Vps34 Complexes by AMPK in Nutrient Stress and Autophagy

(2013) Joungmok Kim et al.   CELL

Regulation of NF-κB by ubiquitination

(2013) Jueqi Chen et al.   CURRENT OPINION IN IMMUNOLOGY

Control of Epithelial Cell Migration and Invasion by the IKKβ- and CK1α-Mediated Degradation of RAPGEF2

(2013) Roberto Magliozzi et al.   DEVELOPMENTAL CELL

Low SOX17 expression is a prognostic factor and drives transcriptional dysregulation and esophageal cancer progression

(2013) I-Ying Kuo et al.   INTERNATIONAL JOURNAL OF CANCER

ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase

(2013) Ryan C. Russell et al.   NATURE CELL BIOLOGY

Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity

(2013) Austin M Dulak et al.   NATURE GENETICS

Integrated molecular analysis of clear-cell renal cell carcinoma

(2013) Yusuke Sato et al.   NATURE GENETICS

The Cancer Genome Atlas Pan-Cancer analysis project

(2013) John N Weinstein et al.   NATURE GENETICS

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

Targeting pathological B cell receptor signalling in lymphoid malignancies

(2013) Ryan M. Young et al.   NATURE REVIEWS DRUG DISCOVERY

Casein Kinase 1 Alpha Regulates Chromosome Congression and Separation during Mouse Oocyte Meiotic Maturation and Early Embryo Development

(2013) Lu Wang et al.   PLoS One

RNA Helicase DDX3 Is a Regulatory Subunit of Casein Kinase 1 in Wnt- -Catenin Signaling

(2013) C.-M. Cruciat et al.   SCIENCE

Systems Biology Approach Identifies the Kinase Csnk1a1 as a Regulator of the DNA Damage Response in Embryonic Stem Cells

(2013) J. Carreras Puigvert et al.   Science Signaling

Wnt Signaling and the Control of Human Stem Cell Fate

(2013) J. K. Van Camp et al.   Stem Cell Reviews and Reports

Stromal Cell Derived Factor-1α Promotes C-Kit+Cardiac Stem/Progenitor Cell Quiescence Through Casein Kinase 1α and GSK3β

(2013) Neviana Dimova et al.   STEM CELLS

Mechanisms of dopamine transporter regulation in normal and disease states

(2013) Roxanne A. Vaughan et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Targeting the Wnt Pathway in Synovial Sarcoma Models

(2013) W. Barham et al.   Cancer Discovery

Exploiting Synthetic Lethality for the Therapy of ABC Diffuse Large B Cell Lymphoma

(2012) Yibin Yang et al.   CANCER CELL

MiR-155 Is a Liposarcoma Oncogene That Targets Casein Kinase-1  and Enhances  -Catenin Signaling

(2012) P. Zhang et al.   CANCER RESEARCH

The Hairpin-type Tail-Anchored SNARE Syntaxin 17 Targets to Autophagosomes for Fusion with Endosomes/Lysosomes

(2012) Eisuke Itakura et al.   CELL

Protein Kinase CK1α Regulates Erythrocyte Survival

(2012) Christine Zelenak et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Casein Kinase 1  Regulates an MDMX Intramolecular Interaction To Stimulate p53 Binding

(2012) S. Wu et al.   MOLECULAR AND CELLULAR BIOLOGY

Exploiting the MDM2-CK1α Protein-Protein Interface to Develop Novel Biologics That Induce UBL-Kinase-Modification and Inhibit Cell Growth

(2012) Anne-Sophie Huart et al.   PLoS One

Structural and molecular basis of interaction of HCV non-structural protein 5A with human casein kinase 1α and PKR

(2012) Govindarajan Sudha et al.   BMC STRUCTURAL BIOLOGY

Reprofiling a classical anthelmintic, pyrvinium pamoate, as an anti-cancer drug targeting mitochondrial respiration

(2012) Isao Ishii et al.   Frontiers in Oncology

A comprehensive siRNA screen for kinases that suppress macroautophagy in optimal growth conditions

(2011) Piotr Szyniarowski et al.   Autophagy

A randomized phase 3 study of lenalidomide versus placebo in RBC transfusion-dependent patients with Low-/Intermediate-1-risk myelodysplastic syndromes with del5q

(2011) P. Fenaux et al.   BLOOD

Non-specific in vivo inhibition of CK1 by the pyridinyl imidazole p38 inhibitors SB 203580 and SB 202190

(2011) Naval P. Shanware et al.   BMB Reports

GLIPR1 Suppresses Prostate Cancer Development through Targeted Oncoprotein Destruction

(2011) L. Li et al.   CANCER RESEARCH

CK1ε targets Cdc25A for ubiquitin-mediated proteolysis under normal conditions and in response to checkpoint activation

(2011) Shunfu Piao et al.   CELL CYCLE

CK1α participle à l’immunité adaptive et à la lymphomagenèse

(2011) Nicolas Bidère   M S-MEDECINE SCIENCES

Differential expression patterns of capping protein, protein phosphatase 1, and casein kinase 1 may serve as diagnostic markers for malignant melanoma

(2011) Daxin Sun et al.   MELANOMA RESEARCH

DEPTOR, an mTOR Inhibitor, Is a Physiological Substrate of SCFβTrCP E3 Ubiquitin Ligase and Regulates Survival and Autophagy

(2011) Yongchao Zhao et al.   MOLECULAR CELL

mTOR Generates an Auto-Amplification Loop by Triggering the βTrCP- and CK1α-Dependent Degradation of DEPTOR

(2011) Shanshan Duan et al.   MOLECULAR CELL

mTOR Drives Its Own Activation via SCFβTrCP-Dependent Degradation of the mTOR Inhibitor DEPTOR

(2011) Daming Gao et al.   MOLECULAR CELL

CKIα ablation highlights a critical role for p53 in invasiveness control

(2011) Ela Elyada et al.   NATURE

Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity

(2011) Theonie Anastassiadis et al.   NATURE BIOTECHNOLOGY

Gene Expression Meta-Analysis Identifies VDAC1 as a Predictor of Poor Outcome in Early Stage Non-Small Cell Lung Cancer

(2011) Claire Grills et al.   PLoS One

RNAi Screen Reveals Host Cell Kinases Specifically Involved in Listeria monocytogenes Spread from Cell to Cell

(2011) Ryan Chong et al.   PLoS One

Sonic Hedgehog Dependent Phosphorylation by CK1α and GRK2 Is Required for Ciliary Accumulation and Activation of Smoothened

(2011) Yongbin Chen et al.   PLOS BIOLOGY

Protein Kinase CK1αLS Promotes Vascular Cell Proliferation and Intimal Hyperplasia

(2010) Mikhail P. Panchenko et al.   AMERICAN JOURNAL OF PATHOLOGY

Molecular imaging of glycogen synthase kinase-3β and casein kinase-1α kinases

(2010) Shyam Nyati et al.   ANALYTICAL BIOCHEMISTRY

Genome wide analysis of DNA copy number neutral loss of heterozygosity (CNNLOH) and its relation to gene expression in esophageal squamous cell carcinoma

(2010) Nan Hu et al.   BMC GENOMICS

Suppression of Casein Kinase 1  in Melanoma Cells Induces a Switch in  -Catenin Signaling to Promote Metastasis

(2010) T. Sinnberg et al.   CANCER RESEARCH

Diuretics in clinical practice. Part I: mechanisms of action, pharmacological effects and clinical indications of diuretic compounds

(2010) Pantelis A Sarafidis et al.   Expert Opinion On Drug Safety

The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy

(2010) Sabrina Di Bartolomeo et al.   JOURNAL OF CELL BIOLOGY

Interplay between BCL10, MALT1 and I B  during T-cell-receptor-mediated NF B activation

(2010) G. Carvalho et al.   JOURNAL OF CELL SCIENCE

Expression Signature of E2F1 and Its Associated Genes Predict Superficial to Invasive Progression of Bladder Tumors

(2010) Ju-Seog Lee et al.   JOURNAL OF CLINICAL ONCOLOGY

Caspase activation precedes and leads to tangles

(2010) Alix de Calignon et al.   NATURE

Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α

(2010) Curtis A Thorne et al.   Nature Chemical Biology

Casein kinase 1 functions as both penultimate and ultimate kinase in regulating Cdc25A destruction

(2010) Y Honaker et al.   ONCOGENE

Pyrvinium, a Potent Small Molecule Wnt Inhibitor, Promotes Wound Repair and Post-MI Cardiac Remodeling

(2010) Sarika Saraswati et al.   PLoS One

Prognostic Biomarkers for Esophageal Adenocarcinoma Identified by Analysis of Tumor Transcriptome

(2010) Soo Mi Kim et al.   PLoS One

High-Throughput Chemical Screen Identifies a Novel Potent Modulator of Cellular Circadian Rhythms and Reveals CKIα as a Clock Regulatory Kinase

(2010) Tsuyoshi Hirota et al.   PLOS BIOLOGY

A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy

(2009) Carol A. Mercer et al.   Autophagy

Role of ULK-FIP200 complex in mammalian autophagy: FIP200, a counterpart of yeast Atg17?

(2009) Taichi Hara et al.   Autophagy

Atg101, a novel mammalian autophagy protein interacting with Atg13

(2009) Nao Hosokawa et al.   Autophagy

FKBP51 Affects Cancer Cell Response to Chemotherapy by Negatively Regulating Akt

(2009) Huadong Pei et al.   CANCER CELL

Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation

(2009) YoungSik Cho et al.   CELL

A Two-Step Model for Colon Adenoma Initiation and Progression Caused by APC Loss

(2009) Reid A. Phelps et al.   CELL

DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival

(2009) Timothy R. Peterson et al.   CELL

Inducible Priming Phosphorylation Promotes Ligand-independent Degradation of the IFNAR1 Chain of Type I Interferon Receptor

(2009) Sabyasachi Bhattacharya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CK1α Plays a Central Role in Mediating MDM2 Control of p53 and E2F-1 Protein Stability

(2009) Anne-Sophie Huart et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophosphorylation of carboxy-terminal residues inhibits the activity of protein kinase CK1α

(2009) Mauricio Budini et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

 -TrCP-Mediated Ubiquitination and Degradation of PHLPP1 Are Negatively Regulated by Akt

(2009) X. Li et al.   MOLECULAR AND CELLULAR BIOLOGY

Mammalian Casein Kinase 1  and Its Leishmanial Ortholog Regulate Stability of IFNAR1 and Type I Interferon Signaling

(2009) J. Liu et al.   MOLECULAR AND CELLULAR BIOLOGY

Casein kinase 1α governs antigen-receptor-induced NF-κB activation and human lymphoma cell survival

(2009) Nicolas Bidère et al.   NATURE

Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1–phosphatidylinositol-3-kinase complex

(2009) Yun Zhong et al.   NATURE CELL BIOLOGY

Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages

(2009) Kohichi Matsunaga et al.   NATURE CELL BIOLOGY

CKI / -dependent phosphorylation is a temperature-insensitive, period-determining process in the mammalian circadian clock

(2009) Y. Isojima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The flaviviral methyltransferase is a substrate of Casein Kinase 1

(2009) Dipankar Bhattacharya et al.   VIRUS RESEARCH

Rac1 Activation Controls Nuclear Localization of β-catenin during Canonical Wnt Signaling

(2008) Ximei Wu et al.   CELL

A Central Role for CK1 in Catalyzing Phosphorylation of the p53 Transactivation Domain at Serine 20 after HHV-6B Viral Infection

(2008) Nicola J. MacLaine et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Jade-1 inhibits Wnt signalling by ubiquitylating β-catenin and mediates Wnt pathway inhibition by pVHL

(2008) Vipul C. Chitalia et al.   NATURE CELL BIOLOGY

Kinome siRNA Screen Identifies Regulators of Ciliogenesis and Hedgehog Signal Transduction

(2008) M. Evangelista et al.   Science Signaling

Casein Kinase 1α Interacts with RIP1 and Regulates NF-κB Activation†

(2007) Yong Wang et al.   BIOCHEMISTRY