HSF1 stress response pathway regulates autophagy receptor SQSTM1/p62-associated proteostasis

Serine 403-phosphorylated p62/SQSTM1 immunoreactivity in inclusions of neurodegenerative diseases

(2016) Masaru Kurosawa et al.   NEUROSCIENCE RESEARCH

The Biology of Proteostasis in Aging and Disease

(2015) Johnathan Labbadia et al.   Annual Review of Biochemistry

PSMD10/gankyrin induces autophagy to promote tumor progression through cytoplasmic interaction with ATG7 and nuclear transactivation of ATG7 expression

(2015) Tao Luo et al.   Autophagy

p62/SQSTM1 functions as a signaling hub and an autophagy adaptor

(2015) Yoshinori Katsuragi et al.   FEBS Journal

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

(2015) Michael Lazarou et al.   NATURE

Amino-terminal arginylation targets endoplasmic reticulum chaperone BiP for autophagy through p62 binding

(2015) Hyunjoo Cha-Molstad et al.   NATURE CELL BIOLOGY

ATG12–ATG3 interacts with Alix to promote basal autophagic flux and late endosome function

(2015) Lyndsay Murrow et al.   NATURE CELL BIOLOGY

Lysosomal enzyme cathepsin B enhances the aggregate forming activity of exogenous α-synuclein fibrils

(2015) Atsushi Tsujimura et al.   NEUROBIOLOGY OF DISEASE

Proteotoxic Stress Induces Phosphorylation of p62/SQSTM1 by ULK1 to Regulate Selective Autophagic Clearance of Protein Aggregates

(2015) Junghyun Lim et al.   PLoS Genetics

Oligomerization of p62 allows for selection of ubiquitinated cargo and isolation membrane during selective autophagy

(2015) Bettina Wurzer et al.   eLife

p62 Plays a Protective Role in the Autophagic Degradation of Polyglutamine Protein Oligomers in Polyglutamine Disease Model Flies

(2014) Yuji Saitoh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteasome Dysfunction Activates Autophagy and the Keap1-Nrf2 Pathway

(2014) Shun Kageyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential Expression of Alpha-Synuclein in Hippocampal Neurons

(2014) Katsutoshi Taguchi et al.   PLoS One

Heat Shock Factor 1 (HSF1) Controls Chemoresistance and Autophagy through Transcriptional Regulation of Autophagy-related Protein 7 (ATG7)

(2013) Shruti Desai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The LC3 interactome at a glance

(2013) P. Wild et al.   JOURNAL OF CELL SCIENCE

Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy

(2013) Yoshinobu Ichimura et al.   MOLECULAR CELL

p62/SQSTM1-Dependent Autophagy of Lewy Body-Like α-Synuclein Inclusions

(2013) Yoshihisa Watanabe et al.   PLoS One

Ubiquitination and selective autophagy

(2012) S Shaid et al.   CELL DEATH AND DIFFERENTIATION

TBK-1 Promotes Autophagy-Mediated Antimicrobial Defense by Controlling Autophagosome Maturation

(2012) Manohar Pilli et al.   IMMUNITY

XBP1mRNA Splicing Triggers an Autophagic Response in Endothelial Cells throughBECLIN-1Transcriptional Activation

(2012) Andriana Margariti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pathological  -Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice

(2012) K. C. Luk et al.   SCIENCE

Selective autophagy mediated by autophagic adapter proteins

(2011) Terje Johansen et al.   Autophagy

p62 targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding

(2011) Eisuke Itakura et al.   JOURNAL OF CELL BIOLOGY

p62/SQSTM1 in autophagic clearance of a non-ubiquitylated substrate

(2011) Y. Watanabe et al.   JOURNAL OF CELL SCIENCE

Serine 403 Phosphorylation of p62/SQSTM1 Regulates Selective Autophagic Clearance of Ubiquitinated Proteins

(2011) Gen Matsumoto et al.   MOLECULAR CELL

The Stress of Protein Misfolding: From Single Cells to Multicellular Organisms

(2011) T. Gidalevitz et al.   Cold Spring Harbor Perspectives in Biology

Fighting disease by selective autophagy of aggregate-prone proteins

(2010) Helene Knaevelsrud et al.   FEBS LETTERS

Physiological significance of selective degradation of p62 by autophagy

(2010) Masaaki Komatsu et al.   FEBS LETTERS

KRIBB11 Inhibits HSP70 Synthesis through Inhibition of Heat Shock Factor 1 Function by Impairing the Recruitment of Positive Transcription Elongation Factor b to thehsp70Promoter

(2010) Young Ju Yoon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extracellular neurosin degrades α-synuclein in cultured cells

(2010) Harutsugu Tatebe et al.   NEUROSCIENCE RESEARCH

Dopamine facilitates α-synuclein oligomerization in human neuroblastoma SH-SY5Y cells

(2009) Kentaro Yamakawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

PLIC proteins or ubiquilins regulate autophagy-dependent cell survival during nutrient starvation

(2009) Elsa-Noah N'Diaye et al.   EMBO REPORTS

A novel splicing variant form suppresses the activity of full-length signal transducer and activator of transcription 5A

(2009) Yoshihisa Watanabe et al.   FEBS Journal

Nucleocytoplasmic Shuttling of p62/SQSTM1 and Its Role in Recruitment of Nuclear Polyubiquitinated Proteins to Promyelocytic Leukemia Bodies

(2009) Serhiy Pankiv et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HSF1-mediated BAG3 Expression Attenuates Apoptosis in 4-Hydroxynonenal-treated Colon Cancer Cells via Stabilization of Anti-apoptotic Bcl-2 Proteins

(2009) Aaron T. Jacobs et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy Inhibition Compromises Degradation of Ubiquitin-Proteasome Pathway Substrates

(2009) Viktor I. Korolchuk et al.   MOLECULAR CELL

Enhanced interaction between Hsp90 and raptor regulates mTOR signaling upon T cell activation

(2009) Greg M. Delgoffe et al.   MOLECULAR IMMUNOLOGY

Stress-Inducible Regulation of Heat Shock Factor 1 by the Deacetylase SIRT1

(2009) S. D. Westerheide et al.   SCIENCE

A Novel Consensus Phosphorylation Motif in Sulfatide- and Cholesterol-3-sulfate-Binding Protein Substrates for CK1 in Vitro

(2008) Fumitaka Kawakami et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN