High-Throughput Chemical Screen Identifies a Novel Potent Modulator of Cellular Circadian Rhythms and Reveals CKIα as a Clock Regulatory Kinase

A serine cluster mediates BMAL1-dependent CLOCK phosphorylation and degradation

(2011) Mary L. Spengler et al.   CELL CYCLE

Regulation of BMAL1 Protein Stability and Circadian Function by GSK3β-Mediated Phosphorylation

(2010) Saurabh Sahar et al.   PLoS One

A Genome-wide RNAi Screen for Modifiers of the Circadian Clock in Human Cells

(2009) Eric E. Zhang et al.   CELL

High-Throughput Screening and Chemical Biology: New Approaches for Understanding Circadian Clock Mechanisms

(2009) Tsuyoshi Hirota et al.   CHEMISTRY & BIOLOGY

A large-scale functional RNAi screen reveals a role for CK2 in the mammalian circadian clock

(2009) B. Maier et al.   GENES & DEVELOPMENT

Selective Inhibition of Casein Kinase 1  Minimally Alters Circadian Clock Period

(2009) K. M. Walton et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Casein Kinase 1 Delta Regulates the Pace of the Mammalian Circadian Clock

(2009) J.-P. Etchegaray et al.   MOLECULAR AND CELLULAR BIOLOGY

Quantitative Proteomics Reveals a Dynamic Interactome and Phase-Specific Phosphorylation in the Neurospora Circadian Clock

(2009) Christopher L. Baker et al.   MOLECULAR CELL

Target profiling of small molecules by chemical proteomics

(2009) Uwe Rix et al.   Nature Chemical Biology

Metabolism control by the circadian clock and vice versa

(2009) Kristin Eckel-Mahan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

CK2α phosphorylates BMAL1 to regulate the mammalian clock

(2009) Teruya Tamaru et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Interactions between Casein Kinase Iε (CKIε) and Two Substrates from Disparate Signaling Pathways Reveal Mechanisms for Substrate-Kinase Specificity

(2009) Caroline Lund Dahlberg et al.   PLoS One

Essential roles of CKIδ and CKIε in the mammalian circadian clock

(2009) Hyeongmin Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CKI / -dependent phosphorylation is a temperature-insensitive, period-determining process in the mammalian circadian clock

(2009) Y. Isojima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Involvement of the Protein Kinase CK2 in the Regulation of Mammalian Circadian Rhythms

(2009) Y. Tsuchiya et al.   Science Signaling

Network Features of the Mammalian Circadian Clock

(2009) Julie E Baggs et al.   PLOS BIOLOGY

The Meter of Metabolism

(2008) Carla B. Green et al.   CELL

Soluble 3′,6-Substituted Indirubins with Enhanced Selectivity toward Glycogen Synthase Kinase -3 Alter Circadian Period

(2008) Konstantina Vougogiannopoulou et al.   JOURNAL OF MEDICINAL CHEMISTRY

Mitogen-Activated Protein Kinase Is a Functional Component of the Autonomous Circadian System in the Suprachiasmatic Nucleus

(2008) M. Akashi et al.   JOURNAL OF NEUROSCIENCE

A quantitative analysis of kinase inhibitor selectivity

(2008) Mazen W Karaman et al.   NATURE BIOTECHNOLOGY

Gene expression signatures and small-molecule compounds link a protein kinase to Plasmodium falciparum motility

(2008) Nobutaka Kato et al.   Nature Chemical Biology

The genetics of mammalian circadian order and disorder: implications for physiology and disease

(2008) Joseph S. Takahashi et al.   NATURE REVIEWS GENETICS

Setting Clock Speed in Mammals: The CK1ɛ tau Mutation in Mice Accelerates Circadian Pacemakers by Selectively Destabilizing PERIOD Proteins

(2008) Qing-Jun Meng et al.   NEURON

A chemical biology approach reveals period shortening of the mammalian circadian clock by specific inhibition of GSK-3 

(2008) T. Hirota et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In silicoactivity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen

(2008) David Plouffe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA