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Title
Wnt Signaling and the Control of Human Stem Cell Fate
Authors
Keywords
Wnt, Human, Embryonic stem cells, Adult stem cells, Canonical, Noncanonical
Journal
Stem Cell Reviews and Reports
Volume 10, Issue 2, Pages 207-229
Publisher
Springer Nature
Online
2013-12-09
DOI
10.1007/s12015-013-9486-8
References
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- (2013) Marta B. Wisniewska NEUROCHEMICAL RESEARCH
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- Signaling networks in human pluripotent stem cells
- (2012) Stephen Dalton CURRENT OPINION IN CELL BIOLOGY
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- (2012) Hyun Kyoung Lee et al. DEVELOPMENTAL CELL
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- (2012) Benjamin L. Martin et al. DEVELOPMENTAL CELL
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- (2012) S. Yoshioka et al. MOLECULAR CANCER RESEARCH
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- (2012) Anna Alkelai et al. PLoS One
- Wnt/ -catenin signaling promotes differentiation, not self-renewal, of human embryonic stem cells and is repressed by Oct4
- (2012) K. C. Davidson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Wnt signaling in myogenesis
- (2012) Julia von Maltzahn et al. TRENDS IN CELL BIOLOGY
- Wnt Signaling in Skin Development, Homeostasis, and Disease
- (2012) X. Lim et al. Cold Spring Harbor Perspectives in Biology
- Wnt Signaling in Cancer
- (2012) P. Polakis Cold Spring Harbor Perspectives in Biology
- Wnt Signaling, Stem Cells, and Cancer of the Gastrointestinal Tract
- (2012) A. Schepers et al. Cold Spring Harbor Perspectives in Biology
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- (2012) Carolina Medina-Gomez et al. PLoS Genetics
- Wnt Signaling Orchestration with a Small Molecule DYRK Inhibitor Provides Long-Term Xeno-Free Human Pluripotent Cell Expansion
- (2012) Kouichi Hasegawa et al. Stem Cells Translational Medicine
- Sclerostin: Therapeutic Horizons Based Upon Its Actions
- (2012) Aline G. Costa et al. Current Osteoporosis Reports
- How do they do Wnt they do?: regulation of transcription by the Wnt/β-catenin pathway
- (2011) H. C. Archbold et al. Acta Physiologica
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- (2011) Élie Abed et al. ARTHRITIS AND RHEUMATISM
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- (2011) Kathrin A. Dunlap et al. BIOLOGY OF REPRODUCTION
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- (2010) M. B. Wisniewska et al. JOURNAL OF NEUROSCIENCE
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- (2010) Toshiro Sato et al. NATURE
- Cancer stem cells at the crossroads of current cancer therapy failures—Radiation oncology perspective
- (2010) Ulrike Koch et al. SEMINARS IN CANCER BIOLOGY
- Wnt signaling in stem and cancer stem cells
- (2010) Peter Wend et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
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- (2009) F.H.J. van Tienen et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- (2009) Guizhong Liu et al. JOURNAL OF CELL BIOLOGY
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