Evaluation of dietary and lifestyle changes as modifiers of S100β levels in Alzheimer’s disease

Effects of a dietary ketone ester on hippocampal glycolytic and tricarboxylic acid cycle intermediates and amino acids in a 3xTgAD mouse model of Alzheimer's disease

(2017) Robert J. Pawlosky et al.   JOURNAL OF NEUROCHEMISTRY

Plasma protein profiling for potential biomarkers in the early diagnosis of Alzheimer’s disease

(2017) Yuki Kitamura et al.   NEUROLOGICAL RESEARCH

Association of Docosahexaenoic Acid Supplementation With Alzheimer Disease Stage in Apolipoprotein E ε4 Carriers

(2017) Hussein N. Yassine et al.   JAMA Neurology

Direct Hits to the Head during Amateur Boxing is Associated with a Rise in Serum Biomarkers for Brain Injury

(2017) M.R. Graham et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

The Alzheimer's Disease Mitochondrial Cascade Hypothesis

(2017) Russell H. Swerdlow et al.   JOURNAL OF ALZHEIMERS DISEASE

Serum S100B as a Surrogate Biomarker in the Diagnoses of Burnout and Depression in Emergency Medicine Residents

(2016) Bedia Gulen et al.   ACADEMIC EMERGENCY MEDICINE

Reversal of cognitive decline in Alzheimer's disease

(2016) Dale Bredesen et al.   Aging-US

The addition of S100B to guidelines for management of mild head injury is potentially cost saving

(2016) Olga Calcagnile et al.   BMC Neurology

Preanalytical, analytical, gestational and pediatric aspects of the S100B immuno-assays

(2016) Damien Bouvier et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Early CSF and Serum S100B Concentrations for Outcome Prediction in Traumatic Brain Injury and Subarachnoid Hemorrhage

(2016) Isabel Kellermann et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Identifying S100B as a Biomarker and a Therapeutic Target For Brain Injury and Multiple Diseases

(2016) Zhao Zhong Chong et al.   CURRENT MEDICINAL CHEMISTRY

Use of S-100B, NSE, CRP and ESR to predict neurological outcomes in patients with return of spontaneous circulation and treated with hypothermia

(2016) Seungwoon Choi et al.   EMERGENCY MEDICINE JOURNAL

Novel ketone diet enhances physical and cognitive performance

(2016) Andrew J. Murray et al.   FASEB JOURNAL

Association of Seafood Consumption, Brain Mercury Level, and APOE ε4 Status With Brain Neuropathology in Older Adults

(2016) Martha Clare Morris et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Unraveling Alzheimer’s: Making Sense of the Relationship between Diabetes and Alzheimer’s Disease1

(2016) Melissa A. Schilling   JOURNAL OF ALZHEIMERS DISEASE

The pleiotropic effects of omega-3 docosahexaenoic acid on the hallmarks of Alzheimer's disease

(2016) Mounir Belkouch et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Timing of Physical Activity, Apolipoprotein Eε4 Genotype, and Risk of Incident Mild Cognitive Impairment

(2016) Janina Krell-Roesch et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

The Effects of Resveratrol Supplementation in Overweight and Obese Humans: A Systematic Review of Randomized Trials

(2016) Julia Christenson et al.   Metabolic Syndrome and Related Disorders

Insulin Stimulates S100B Secretion and These Proteins Antagonistically Modulate Brain Glucose Metabolism

(2016) Krista Minéia Wartchow et al.   NEUROCHEMICAL RESEARCH

Clinical value of nutritional status in neurodegenerative diseases: What is its impact and how it affects disease progression and management?

(2016) Eftyhia Tsagalioti et al.   NUTRITIONAL NEUROSCIENCE

S-100 B Concentrations Are a Predictor of Decreased Survival in Patients with Major Trauma, Independently of Head Injury

(2016) Carmen Andrea Pfortmueller et al.   PLoS One

Blood-Brain Barrier Leakage in Patients with Early Alzheimer Disease

(2016) Harm J. van de Haar et al.   RADIOLOGY

Amyloid-β peptide protects against microbial infection in mouse and worm models of Alzheimer’s disease

(2016) Deepak Kumar Vijaya Kumar et al.   Science Translational Medicine

Sleep, Cognitive impairment, and Alzheimer’s disease: A Systematic Review and Meta-Analysis

(2016) Omonigho M. Bubu et al.   SLEEP

Sleep: A Novel Mechanistic Pathway, Biomarker, and Treatment Target in the Pathology of Alzheimer's Disease?

(2016) Bryce A. Mander et al.   TRENDS IN NEUROSCIENCES

Sleep, Cognitive impairment, and Alzheimer’s disease: A Systematic Review and Meta-Analysis

(2016) Omonigho M. Bubu et al.   SLEEP

Reversal of cognitive decline: A novel therapeutic program

(2016) Dale E. Bredesen   Aging-US

High-Fat Diet Changes Hippocampal Apolipoprotein E (ApoE) in a Genotype- and Carbohydrate-Dependent Manner in Mice

(2016) Courtney Lane-Donovan et al.   PLoS One

A new way to produce hyperketonemia: Use of ketone ester in a case of Alzheimer's disease

(2015) Mary T. Newport et al.   Alzheimers & Dementia

MIND diet slows cognitive decline with aging

(2015) Martha Clare Morris et al.   Alzheimers & Dementia

Plasma levels of apolipoprotein E and risk of dementia in the general population

(2015) Katrine L. Rasmussen et al.   ANNALS OF NEUROLOGY

Curcumin boosts DHA in the brain: Implications for the prevention of anxiety disorders

(2015) Aiguo Wu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Western diet is associated with a smaller hippocampus: a longitudinal investigation

(2015) Felice N. Jacka et al.   BMC Medicine

The genetic landscape of Alzheimer disease: clinical implications and perspectives

(2015) Caroline Van Cauwenberghe et al.   GENETICS IN MEDICINE

Accelerated pericyte degeneration and blood–brain barrier breakdown in apolipoprotein E4 carriers with Alzheimer’s disease

(2015) Matthew R Halliday et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Saturated Fats Compared With Unsaturated Fats and Sources of Carbohydrates in Relation to Risk of Coronary Heart Disease

(2015) Yanping Li et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial

(2015) Tiia Ngandu et al.   LANCET

Immune attack: the role of inflammation in Alzheimer disease

(2015) Frank L. Heppner et al.   NATURE REVIEWS NEUROSCIENCE

Lack of Widespread BBB Disruption in Alzheimer’s Disease Models: Focus on Therapeutic Antibodies

(2015) Nga Bien-Ly et al.   NEURON

Blood-Brain Barrier Breakdown in the Aging Human Hippocampus

(2015) Axel Montagne et al.   NEURON

Ketogenic diet in epileptic children: impact on lipoproteins and oxidative stress

(2015) Patricia Azevedo Lima et al.   NUTRITIONAL NEUROSCIENCE

Diet-Induced Cognitive Deficits: The Role of Fat and Sugar, Potential Mechanisms and Nutritional Interventions

(2015) Jessica Beilharz et al.   Nutrients

Dietary Patterns, Cognitive Decline, and Dementia: A Systematic Review

(2015) Ondine van de Rest et al.   Advances in Nutrition

Intake of saturated and trans unsaturated fatty acids and risk of all cause mortality, cardiovascular disease, and type 2 diabetes: systematic review and meta-analysis of observational studies

(2015) Russell J de Souza et al.   BMJ-British Medical Journal

Intake of saturated and trans unsaturated fatty acids and risk of all cause mortality, cardiovascular disease, and type 2 diabetes: systematic review and meta-analysis of observational studies

(2015) Russell J de Souza et al.   BMJ-British Medical Journal

Association of Insulin Resistance With Cerebral Glucose Uptake in Late Middle–Aged Adults at Risk for Alzheimer Disease

(2015) Auriel A. Willette et al.   JAMA Neurology

Low Plasma ApoE Levels Are Associated with Smaller Hippocampal Size in the Alzheimer's Disease Neuroimaging Initiative Cohort

(2015) Edmond Teng et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

The role of inflammasome in Alzheimer's disease

(2014) Li Liu et al.   AGEING RESEARCH REVIEWS

How does brain insulin resistance develop in Alzheimer's disease?

(2014) Fernanda G. De Felice et al.   Alzheimers & Dementia

Intake of Long-Chain  -3 Fatty Acids From Diet and Supplements in Relation to Mortality

(2014) G. A. Bell et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Association of Dietary, Circulating, and Supplement Fatty Acids With Coronary Risk

(2014) Rajiv Chowdhury et al.   ANNALS OF INTERNAL MEDICINE

Alzheimer disease therapeutics: Focus on the disease and not just plaques and tangles

(2014) Khalid Iqbal et al.   BIOCHEMICAL PHARMACOLOGY

Prediction of neuropsychological outcome after mild traumatic brain injury using clinical parameters, serum S100B protein and findings on computed tomography

(2014) Kamran Heidari et al.   BRAIN INJURY

Quercetin Administration After Spinal Cord Trauma Changes S-100β Levels

(2014) E. Schültke et al.   CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES

Neurobiochemical mechanisms of a ketogenic diet in refractory epilepsy

(2014) PA Lima et al.   Clinics

The APOE Genotype: Modification of Therapeutic Responses in Alzheimer's Disease

(2014) Angela Hanson et al.   CURRENT PHARMACEUTICAL DESIGN

Type 3 diabetes is sporadic Alzheimer׳s disease: Mini-review

(2014) Suzanne M. de la Monte   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Nutrient patterns and brain biomarkers of Alzheimer’s disease in cognitively normal individuals

(2014) V. Berti et al.   Journal of Nutrition Health & Aging

Cinnamon polyphenols attenuate the hydrogen peroxide-induced down regulation of S100β secretion by regulating sirtuin 1 in C6 rat glioma cells

(2014) Bolin Qin et al.   LIFE SCIENCES

Apolipoprotein E (APOE) genotype regulates body weight and fatty acid utilization-Studies in gene-targeted replacement mice

(2014) Patricia Huebbe et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Dietary patterns and cognitive decline in an Australian study of ageing

(2014) S L Gardener et al.   MOLECULAR PSYCHIATRY

Apolipoprotein E and lipid homeostasis in the etiology and treatment of sporadic Alzheimer's disease

(2014) Judes Poirier et al.   NEUROBIOLOGY OF AGING

Saturated and trans fats and dementia: a systematic review

(2014) Neal D. Barnard et al.   NEUROBIOLOGY OF AGING

Apolipoprotein E: Structure and function in lipid metabolism, neurobiology, and Alzheimer's diseases

(2014) Yadong Huang et al.   NEUROBIOLOGY OF DISEASE

Modifiable Risk Factors for Alzheimer Disease and Subjective Memory Impairment across Age Groups

(2014) Stephen T. Chen et al.   PLoS One

Acute Sleep Deprivation Increases Serum Levels of Neuron-Specific Enolase (NSE) and S100 Calcium Binding Protein B (S-100B) in Healthy Young Men

(2014) Christian Benedict et al.   SLEEP

Blood-brain barrier disruption: mechanistic links between Western diet consumption and dementia

(2014) Ted M. Hsu et al.   Frontiers in Aging Neuroscience

Ketogenic Diet in Neuromuscular and Neurodegenerative Diseases

(2014) Antonio Paoli et al.   Biomed Research International

Effect of the amount and type of dietary fat on cardiometabolic risk factors and risk of developing type 2 diabetes, cardiovascular diseases, and cancer: a systematic review

(2014) Ursula Schwab et al.   Food & Nutrition Research

Insulin in the Brain: Its Pathophysiological Implications for States Related with Central Insulin Resistance, Type 2 Diabetes and Alzheimer’s Disease

(2014) Enrique Blázquez et al.   Frontiers in Endocrinology

National Institutes of Health State-of-the-Science Conference Statement: Preventing Alzheimer Disease and Cognitive Decline

(2013) Martha L. Daviglus   ANNALS OF INTERNAL MEDICINE

Mediterranean diet, stroke, cognitive impairment, and depression: A meta-analysis

(2013) Theodora Psaltopoulou et al.   ANNALS OF NEUROLOGY

Intranasal Insulin as a Treatment for Alzheimer’s Disease: A Review of Basic Research and Clinical Evidence

(2013) Jessica Freiherr et al.   CNS DRUGS

Beyond weight loss: a review of the therapeutic uses of very-low-carbohydrate (ketogenic) diets

(2013) A Paoli et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Brain changes in BDNF and S100B induced by ketogenic diets in Wistar rats

(2013) Adriana Fernanda Vizuete et al.   LIFE SCIENCES

Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy

(2013) Chia-Chen Liu et al.   Nature Reviews Neurology

Glucose Levels and Risk of Dementia

(2013) Paul K. Crane et al.   NEW ENGLAND JOURNAL OF MEDICINE

Consequences of Repeated Blood-Brain Barrier Disruption in Football Players

(2013) Nicola Marchi et al.   PLoS One

Decrease of serum S100B during an oral glucose tolerance test correlates inversely with the insulin response

(2013) Johann Steiner et al.   PSYCHONEUROENDOCRINOLOGY

S100B as a Marker for Brain Damage and Blood–Brain Barrier Disruption Following Exercise

(2013) Serene X. T. Koh et al.   SPORTS MEDICINE

Predictive value of S-100  protein for prognosis in patients with moderate and severe traumatic brain injury: systematic review and meta-analysis

(2013) E. Mercier et al.   BMJ-British Medical Journal

The Serum Concentration of the Calcium Binding Protein S100B is Positively Associated with Cognitive Performance in Older Adults

(2013) Virginie Lam et al.   Frontiers in Aging Neuroscience

The release of S-100B and NSE in severe traumatic head injury is associated with APOE ε4

(2012) Zandra Olivecrona et al.   ACTA NEUROCHIRURGICA

Green tea (−)epigallocatechin-3-gallate reverses oxidative stress and reduces acetylcholinesterase activity in a streptozotocin-induced model of dementia

(2012) Regina Biasibetti et al.   BEHAVIOURAL BRAIN RESEARCH

S100B is increased in Parkinson’s disease and ablation protects against MPTP-induced toxicity through the RAGE and TNF-α pathway

(2012) Kinnari Sathe et al.   BRAIN

Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline

(2012) Konrad Talbot et al.   JOURNAL OF CLINICAL INVESTIGATION

The Molecular Pathology of Alzheimer's Disease

(2012) Charles R. Harrington   NEUROIMAGING CLINICS OF NORTH AMERICA

Validating Serum S100B and Neuron-Specific Enolase as Biomarkers for the Human Brain – A Combined Serum, Gene Expression and MRI Study

(2012) Daniel-Paolo Streitbürger et al.   PLoS One

Cognitive activity, education and socioeconomic status as preventive factors for mild cognitive impairment and Alzheimer's disease

(2012) Christine Sattler et al.   PSYCHIATRY RESEARCH

Effect of aqueous extract of Crocus sativus L. (saffron) stigma against subacute effect of diazinon on specific biomarkers in rats

(2012) Seyed Adel Moallem et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

The ketogenic diet: metabolic influences on brain excitability and epilepsy

(2012) Andrew Lutas et al.   TRENDS IN NEUROSCIENCES

The Dynamics of Cortical and Hippocampal Atrophy in Alzheimer Disease

(2011) Mert R. Sabuncu   ARCHIVES OF NEUROLOGY

Intranasal Insulin Therapy for Alzheimer Disease and Amnestic Mild Cognitive Impairment

(2011) Suzanne Craft   ARCHIVES OF NEUROLOGY

Oral Uncaria rhynchophylla (UR) reduces kainic acid-induced epileptic seizures and neuronal death accompanied by attenuating glial cell proliferation and S100B proteins in rats

(2011) Yi-Wen Lin et al.   JOURNAL OF ETHNOPHARMACOLOGY

Momordica charantia (bitter melon) attenuates high-fat diet-associated oxidative stress and neuroinflammation

(2011) Pratibha V Nerurkar et al.   Journal of Neuroinflammation

Late-Life Social Activity and Cognitive Decline in Old Age

(2011) Bryan D. James et al.   JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY

A genome-wide association study confirms APOE as the major gene influencing survival in long-lived individuals

(2011) Almut Nebel et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Total tau and S100b proteins in different types of multiple sclerosis and during immunosuppressive treatment with mitoxantrone

(2010) H. Bartosik-Psujek et al.   ACTA NEUROLOGICA SCANDINAVICA

Human muscle satellite cells show age-related differential expression of S100B protein and RAGE

(2010) Sara Beccafico et al.   AGE

Cognitive Function after Major Noncardiac Surgery, Apolipoprotein E4 Genotype, and Biomarkers of Brain Injury

(2010) David L. McDonagh et al.   ANESTHESIOLOGY

Silymarin: A Novel Antioxidant with Antiglycation and Antiinflammatory Properties In Vitro and In Vivo

(2010) Chi-Hao Wu et al.   ANTIOXIDANTS & REDOX SIGNALING

S100B Profiles and Cognitive Function at High Altitude

(2010) Henrik Bjursten et al.   HIGH ALTITUDE MEDICINE & BIOLOGY

Serum levels of S100B and NSE proteins in Alzheimer's disease patients

(2010) Márcia L Chaves et al.   Journal of Neuroinflammation

Neuropathology of Alzheimer's Disease

(2010) Daniel P. Perl   MOUNT SINAI JOURNAL OF MEDICINE

Brain fuel metabolism, aging, and Alzheimer’s disease

(2010) Stephen Cunnane et al.   NUTRITION

Western diet consumption and cognitive impairment: Links to hippocampal dysfunction and obesity

(2010) Scott E. Kanoski et al.   PHYSIOLOGY & BEHAVIOR

Extracranial Sources of S100B Do Not Affect Serum Levels

(2010) Nancy Pham et al.   PLoS One

Differential effects of dietary fatty acids on the cerebral distribution of plasma-derived apo B lipoproteins with amyloid-β

(2009) Ryusuke Takechi et al.   BRITISH JOURNAL OF NUTRITION

Adherence to a Mediterranean Diet, Cognitive Decline, and Risk of Dementia

(2009) Catherine Féart   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Study of the ketogenic agent AC-1202 in mild to moderate Alzheimer's disease: a randomized, double-blind, placebo-controlled, multicenter trial

(2009) Samuel T Henderson et al.   Nutrition & Metabolism

S100B serum levels are closely correlated with body mass index: An important caveat in neuropsychiatric research

(2009) Johann Steiner et al.   PSYCHONEUROENDOCRINOLOGY

Persistent treatment with cholinesterase inhibitors and/or memantine slows clinical progression of Alzheimer disease

(2009) Susan D Rountree et al.   Alzheimers Research & Therapy

Comprehensive approach of donepezil and psychosocial interventions on cognitive function and quality of life for Alzheimer's disease: the Osaki-Tajiri Project

(2008) M. Meguro et al.   AGE AND AGEING

S100B's double life: Intracellular regulator and extracellular signal

(2008) Rosario Donato et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

APOE ε4 lowers age at onset and is a high risk factor for Alzheimer's disease; A case control study from central Norway

(2008) Sigrid B Sando et al.   BMC Neurology

Vitamin E increases S100B-mediated microglial activation in an S100B-overexpressing mouse model of pathological aging

(2008) Lynn A. Bialowas-McGoey et al.   GLIA

Serum levels of S100B are decreased in chronic starvation and normalize with weight gain

(2008) Kristian Holtkamp et al.   JOURNAL OF NEURAL TRANSMISSION

S100B/RAGE-dependent activation of microglia via NF-κB and AP-1

(2008) Roberta Bianchi et al.   NEUROBIOLOGY OF AGING

The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

(2008) Berislav V. Zlokovic   NEURON

S100B in underweight and weight-recovered patients with anorexia nervosa

(2008) Stefan Ehrlich et al.   PSYCHONEUROENDOCRINOLOGY