Effects of a dietary ketone ester on hippocampal glycolytic and tricarboxylic acid cycle intermediates and amino acids in a 3xTgAD mouse model of Alzheimer's disease

Novel ketone diet enhances physical and cognitive performance

(2016) Andrew J. Murray et al.   FASEB JOURNAL

A new way to produce hyperketonemia: Use of ketone ester in a case of Alzheimer's disease

(2015) Mary T. Newport et al.   Alzheimers & Dementia

Cholesterol 24-hydroxylase defect is implicated in memory impairments associated with Alzheimer-like Tau pathology

(2015) Marie-Anne Burlot et al.   HUMAN MOLECULAR GENETICS

An Ester of β-Hydroxybutyrate Regulates Cholesterol Biosynthesis in Rats and a Cholesterol Biomarker in Humans

(2015) Martin F. Kemper et al.   LIPIDS

The glucose ketone index calculator: a simple tool to monitor therapeutic efficacy for metabolic management of brain cancer

(2015) Joshua J Meidenbauer et al.   Nutrition & Metabolism

Relative importance of redox buffers GSH and NAD(P)H in age-related neurodegeneration and Alzheimer disease-like mouse neurons

(2014) Debolina Ghosh et al.   AGING CELL

GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease

(2014) Seonmi Jo et al.   NATURE MEDICINE

A ketogenic diet improves motor performance but does not affect β-amyloid levels in a mouse model of Alzheimer's Disease

(2013) Tina L. Beckett et al.   BRAIN RESEARCH

Ovariectomy Induces a Shift in Fuel Availability and Metabolism in the Hippocampus of the Female Transgenic Model of Familial Alzheimer's

(2013) Fan Ding et al.   PLoS One

Ketogenic Diet Improves Motor Performance but Not Cognition in Two Mouse Models of Alzheimer’s Pathology

(2013) Milene L. Brownlow et al.   PLoS One

Early Decline in Glucose Transport and Metabolism Precedes Shift to Ketogenic System in Female Aging and Alzheimer's Mouse Brain: Implication for Bioenergetic Intervention

(2013) Fan Ding et al.   PLoS One

Mitochondrial biogenesis and increased uncoupling protein 1 in brown adipose tissue of mice fed a ketone ester diet

(2012) Shireesh Srivastava et al.   FASEB JOURNAL

Endogenous Ovarian Hormones Affect Mitochondrial Efficiency in Cerebral Endothelium via Distinct Regulation of PGC-1 Isoforms

(2012) Martin F Kemper et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Microwave irradiation decreases ATP, increases free [Mg2+], and altersin vivointracellular reactions in rat brain

(2012) Shireesh Srivastava et al.   JOURNAL OF NEUROCHEMISTRY

A Reversible Early Oxidized Redox State That Precedes Macromolecular ROS Damage in Aging Nontransgenic and 3xTg-AD Mouse Neurons

(2012) D. Ghosh et al.   JOURNAL OF NEUROSCIENCE

A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's disease

(2012) Yoshihiro Kashiwaya et al.   NEUROBIOLOGY OF AGING

Kinetics, safety and tolerability of (R)-3-hydroxybutyl (R)-3-hydroxybutyrate in healthy adult subjects

(2012) Kieran Clarke et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Differential regulation of BACE1 expression by oxidative and nitrosative signals

(2011) Young-Don Kwak et al.   Molecular Neurodegeneration

2-Deoxy-D-Glucose Treatment Induces Ketogenesis, Sustains Mitochondrial Function, and Reduces Pathology in Female Mouse Model of Alzheimer's Disease

(2011) Jia Yao et al.   PLoS One

Brain Glucose Hypometabolism and Oxidative Stress in Preclinical Alzheimer's Disease

(2010) Lisa Mosconi et al.   Annals of the New York Academy of Sciences

A Ketone Ester Diet Increases Brain Malonyl-CoA and Uncoupling Proteins 4 and 5 while Decreasing Food Intake in the Normal Wistar Rat

(2010) Yoshihiro Kashiwaya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Effect of pH and Free Mg2+on ATP Linked Enzymes and the Calculation of Gibbs Free Energy of ATP Hydrolysis†

(2010) Christian Bergman et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Disrupted energy metabolism and neuronal circuit dysfunction in cognitive impairment and Alzheimer's disease

(2010) Dimitrios Kapogiannis et al.   LANCET NEUROLOGY

Dietary ketosis enhances memory in mild cognitive impairment

(2010) Robert Krikorian et al.   NEUROBIOLOGY OF AGING

Brain fuel metabolism, aging, and Alzheimer’s disease

(2010) Stephen Cunnane et al.   NUTRITION

Alterations in Brain Glucose Utilization Accompanying Elevations in Blood Ethanol and Acetate Concentrations in the Rat

(2009) Robert J. Pawlosky et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease

(2009) J. Yao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adaptive mechanisms regulate preferred utilization of ketones in the heart and brain of a hibernating mammal during arousal from torpor

(2008) Matthew T. Andrews et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Hippocampal N-Acetylaspartate Concentration and Response to Riluzole in Generalized Anxiety Disorder

(2007) Sanjay J. Mathew et al.   BIOLOGICAL PSYCHIATRY