Nonribosomal peptide synthetase biosynthetic clusters of ESKAPE pathogens

Domain-Targeted Metabolomics Delineates the Heterocycle Assembly Steps of Colibactin Biosynthesis

(2017) Eric P. Trautman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Modeling Acinetobacter baumannii wound infections

(2017) Irma D. Fleming et al.   Journal of Trauma and Acute Care Surgery

Natural products as mediators of disease

(2017) Neha Garg et al.   NATURAL PRODUCT REPORTS

X-Ray Crystallography and Electron Microscopy of Cross- and Multi-Module Nonribosomal Peptide Synthetase Proteins Reveal a Flexible Architecture

(2017) Michael J. Tarry et al.   STRUCTURE

Novel mechanism of metabolic co-regulation coordinates the biosynthesis of secondary metabolites in Pseudomonas protegens

(2017) Qing Yan et al.   eLife

Contribution of the A. baumannii A1S_0114 Gene to the Interaction with Eukaryotic Cells and Virulence

(2017) Soraya Rumbo-Feal et al.   Frontiers in Cellular and Infection Microbiology

Modeling Acinetobacter baumannii wound infections

(2017) Irma D. Fleming et al.   Journal of Trauma and Acute Care Surgery

Interdomain and Intermodule Organization in Epimerization Domain Containing Nonribosomal Peptide Synthetases

(2016) Wei-Hung Chen et al.   ACS Chemical Biology

New Structural Data Reveal the Motion of Carrier Proteins in Nonribosomal Peptide Synthesis

(2016) Tiia Kittilä et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Holo Structure and Steady State Kinetics of the Thiazolinyl Imine Reductases for Siderophore Biosynthesis

(2016) Kathleen M. Meneely et al.   BIOCHEMISTRY

Functional Characterization of PyrG, an Unusual Nonribosomal Peptide Synthetase Module from the Pyridomycin Biosynthetic Pathway

(2016) Tingting Huang et al.   CHEMBIOCHEM

Structural insight into the necessary conformational changes of modular nonribosomal peptide synthetases

(2016) Andrew M Gulick   CURRENT OPINION IN CHEMICAL BIOLOGY

Linking Biosynthetic Gene Clusters to their Metabolites via Pathway- Targeted Molecular Networking

(2016) Eric P. Trautman et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Incidence and Outcomes Associated With Infections Caused by Vancomycin-Resistant Enterococci in the United States: Systematic Literature Review and Meta-Analysis

(2016) Hsiu-Yin Chiang et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

PvdN Enzyme Catalyzes a Periplasmic Pyoverdine Modification

(2016) Michael T. Ringel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structures of a Nonribosomal Peptide Synthetase Module Bound to MbtH-like Proteins Support a Highly Dynamic Domain Architecture

(2016) Bradley R. Miller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural insights into the regulation of NADPH binding to reductase domains of nonribosomal peptide synthetases: A concerted loop movement model

(2016) Priyadarshan Kinatukara et al.   JOURNAL OF STRUCTURAL BIOLOGY

An Open and Shut Case: The Interaction of Magnesium with MST Enzymes

(2016) Kathleen M. Meneely et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Insights into the chemical logic and enzymatic machinery of NRPS assembly lines

(2016) Christopher T. Walsh   NATURAL PRODUCT REPORTS

Human commensals producing a novel antibiotic impair pathogen colonization

(2016) Alexander Zipperer et al.   NATURE

Microbiome-wide association studies link dynamic microbial consortia to disease

(2016) Jack A. Gilbert et al.   NATURE

Structures of two distinct conformations of holo-non-ribosomal peptide synthetases

(2016) Eric J. Drake et al.   NATURE

Synthetic cycle of the initiation module of a formylating nonribosomal peptide synthetase

(2016) Janice M. Reimer et al.   NATURE

Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking

(2016) Mingxun Wang et al.   NATURE BIOTECHNOLOGY

Structural basis of nonribosomal peptide macrocyclization in fungi

(2016) Jinru Zhang et al.   Nature Chemical Biology

Polyketide and nonribosomal peptide retro-biosynthesis and global gene cluster matching

(2016) Chris A Dejong et al.   Nature Chemical Biology

The antiSMASH database, a comprehensive database of microbial secondary metabolite biosynthetic gene clusters

(2016) Kai Blin et al.   NUCLEIC ACIDS RESEARCH

Genomic Features and Niche-Adaptation of Enterococcus faecium Strains from Korean Soybean-Fermented Foods

(2016) Eun Bae Kim et al.   PLoS One

Structural elements of an NRPS cyclization domain and its intermodule docking domain

(2016) Daniel P. Dowling et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pseudomonas aeruginosa Evolutionary Adaptation and Diversification in Cystic Fibrosis Chronic Lung Infections

(2016) Craig Winstanley et al.   TRENDS IN MICROBIOLOGY

Staphylococcus aureus Exploits a Non-ribosomal Cyclic Dipeptide to Modulate Survival within Epithelial Cells and Phagocytes

(2016) Sebastian Blättner et al.   PLoS Pathogens

Do Bacterial “Virulence Factors” Always Increase Virulence? A Meta-Analysis of Pyoverdine Production in Pseudomonas aeruginosa As a Test Case

(2016) Elisa T. Granato et al.   Frontiers in Microbiology

1.2 Å resolution crystal structure of the periplasmic aminotransferase PvdN fromPseudomonas aeruginosa

(2016) Eric J. Drake et al.   Acta Crystallographica Section F-Structural Biology Communications

Breaking a pathogen's iron will: Inhibiting siderophore production as an antimicrobial strategy

(2015) Audrey L. Lamb   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Identification of genes essential for pellicle formation in Acinetobacter baumannii

(2015) Sarah K. Giles et al.   BMC MICROBIOLOGY

Colibactin biosynthesis and biological activity depend on the rare aminomalonyl polyketide precursor

(2015) A. O. Brachmann et al.   CHEMICAL COMMUNICATIONS

Comprehensive Structural and Biochemical Analysis of the Terminal Myxalamid Reductase Domain for the Engineered Production of Primary Alcohols

(2015) Jesus F. Barajas et al.   CHEMISTRY & BIOLOGY

Three Redundant Synthetases Secure Redox-Active Pigment Production in the Basidiomycete Paxillus involutus

(2015) Jana Braesel et al.   CHEMISTRY & BIOLOGY

Harnessing natural product assembly lines: structure, promiscuity, and engineering

(2015) Christopher C. Ladner et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Structure and Substrate Sequestration in the Pyoluteorin Type II Peptidyl Carrier Protein PltL

(2015) Matt J. Jaremko et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Colibactin: understanding an elusive gut bacterial genotoxin

(2015) Emily P. Balskus   NATURAL PRODUCT REPORTS

β-Lactam formation by a non-ribosomal peptide synthetase during antibiotic biosynthesis

(2015) Nicole M. Gaudelli et al.   NATURE

Minimum Information about a Biosynthetic Gene cluster

(2015) Marnix H Medema et al.   Nature Chemical Biology

Computational approaches to natural product discovery

(2015) Marnix H Medema et al.   Nature Chemical Biology

A chemocentric view of the natural product inventory

(2015) Christopher T Walsh   Nature Chemical Biology

The structural biology of biosynthetic megaenzymes

(2015) Kira J Weissman   Nature Chemical Biology

The colibactin warhead crosslinks DNA

(2015) Maria I. Vizcaino et al.   Nature Chemistry

Isolation of a Metabolite from the pks Island Provides Insights into Colibactin Biosynthesis and Activity

(2015) Carolyn A. Brotherton et al.   ORGANIC LETTERS

Small molecules from the human microbiota

(2015) M. S. Donia et al.   SCIENCE

Two more pieces of the colibactin genotoxin puzzle from Escherichia coli show incorporation of an unusual 1-aminocyclopropanecarboxylic acid moiety

(2015) Xiaoying Bian et al.   Chemical Science

Mapping the Evolution of Hypervirulent Klebsiella pneumoniae

(2015) Carsten Struve et al.   mBio

The Pseudomonas aeruginosa antimetabolite L -2-amino-4-methoxy-trans-3-butenoic acid (AMB) is made from glutamate and two alanine residues via a thiotemplate-linked tripeptide precursor

(2015) Nelson Rojas Murcia et al.   Frontiers in Microbiology

Acinetobactin Isomerization Enables Adaptive Iron Acquisition in Acinetobacter baumannii through pH-Triggered Siderophore Swapping

(2015) Justin A. Shapiro et al.   ACS Infectious Diseases

Functional analysis of pyochelin-/enantiopyochelin-related genes from a pathogenicity island of Pseudomonas aeruginosa strain PA14

(2014) Alessandro Maspoli et al.   BIOMETALS

Plasmid transferability of KPC into a virulent K2 serotype Klebsiella pneumoniae

(2014) Leung-Kei Kristopher Siu et al.   BMC INFECTIOUS DISEASES

Chemistry and Biology of Pyoverdines, Pseudomonas Primary Siderophores

(2014) C. Cezard et al.   CURRENT MEDICINAL CHEMISTRY

Aerobactin Mediates Virulence and Accounts for Increased Siderophore Production under Iron-Limiting Conditions by Hypervirulent (Hypermucoviscous) Klebsiella pneumoniae

(2014) T. A. Russo et al.   INFECTION AND IMMUNITY

Rapid identification ofEnterobacter hormaecheiandEnterobacter cloacaegenetic cluster III

(2014) S. Ohad et al.   JOURNAL OF APPLIED MICROBIOLOGY

PvdP Is a Tyrosinase That Drives Maturation of the Pyoverdine Chromophore in Pseudomonas aeruginosa

(2014) P. Nadal-Jimenez et al.   JOURNAL OF BACTERIOLOGY

Comparative Metabolomics and Structural Characterizations Illuminate Colibactin Pathway-Dependent Small Molecules

(2014) Maria I. Vizcaino et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

TRANSLOCATION Project: How to Get Good Drugs into Bad Bugs

(2014) R. A. Stavenger et al.   Science Translational Medicine

Structural and bioinformatic characterization of anAcinetobacter baumanniitype II carrier protein

(2014) C. Leigh Allen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structure determination of the functional domain interaction of a chimeric nonribosomal peptide synthetase from a challenging crystal with noncrystallographic translational symmetry

(2013) Jesse A. Sundlov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Redesign of MST enzymes to target lyase activity instead promotes mutase and dehydratase activities

(2013) Kathleen M. Meneely et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Characterization of AusA: A Dimodular Nonribosomal Peptide Synthetase Responsible for the Production of Aureusimine Pyrazinones

(2013) Daniel J. Wilson et al.   BIOCHEMISTRY

Cytoplasmic replication ofStaphylococcus aureusupon phagosomal escape triggered by phenol-soluble modulin α

(2013) Magdalena Grosz et al.   CELLULAR MICROBIOLOGY

In Vivo Evidence for a Prodrug Activation Mechanism during Colibactin Maturation

(2013) Xiaoying Bian et al.   CHEMBIOCHEM

Structure and Biosynthesis of Fimsbactins A-F, Siderophores fromAcinetobacter baumanniiandAcinetobacter baylyi

(2013) Anna Proschak et al.   CHEMBIOCHEM

10 x '20 Progress--Development of New Drugs Active Against Gram-Negative Bacilli: An Update From the Infectious Diseases Society of America

(2013) H. W. Boucher et al.   CLINICAL INFECTIOUS DISEASES

Clinical relevance of the ESKAPE pathogens

(2013) Jack N Pendleton et al.   Expert Review of Anti-Infective Therapy

Pseudomonas aeruginosa Uses Multiple Pathways To Acquire Iron during Chronic Infection in Cystic Fibrosis Lungs

(2013) Anna F. Konings et al.   INFECTION AND IMMUNITY

“Nightmare” Bacteria on the Rise in US Hospitals, Long-term Care Facilities

(2013) Bridget M. Kuehn   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Crystal Structures of the First Condensation Domain of CDA Synthetase Suggest Conformational Changes during the Synthetic Cycle of Nonribosomal Peptide Synthetases

(2013) Kristjan Bloudoff et al.   JOURNAL OF MOLECULAR BIOLOGY

A Prodrug Resistance Mechanism Is Involved in Colibactin Biosynthesis and Cytotoxicity

(2013) Carolyn A. Brotherton et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Virulence and Transferability of Resistance Determinants in a Novel Klebsiella pneumoniae Sequence Type 1137 in China

(2013) Yang Liu et al.   Microbial Drug Resistance

A cell-cell communication signal integrates quorum sensing and stress response

(2013) Jasmine Lee et al.   Nature Chemical Biology

Comparative Genome Analysis of Enterobacter cloacae

(2013) Wing-Yee Liu et al.   PLoS One

Whole Transcriptome Analysis of Acinetobacter baumannii Assessed by RNA-Sequencing Reveals Different mRNA Expression Profiles in Biofilm Compared to Planktonic Cells

(2013) Soraya Rumbo-Feal et al.   PLoS One

Repurposing the antimycotic drug flucytosine for suppression of Pseudomonas aeruginosa pathogenicity

(2013) F. Imperi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Switching between apparently redundant iron-uptake mechanisms benefits bacteria in changeable environments

(2013) Z. Dumas et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Acinetobacter baumannii Strain M2 Produces Type IV Pili Which Play a Role in Natural Transformation and Twitching Motility but Not Surface-Associated Motility

(2013) C. M. Harding et al.   mBio

Hypervirulent (hypermucoviscous)Klebsiella pneumoniae

(2013) Alyssa S. Shon et al.   Virulence

Pseudomonas aeruginosa adapts its iron uptake strategies in function of the type of infections

(2013) Pierre Cornelis et al.   Frontiers in Cellular and Infection Microbiology

Pseudomonas aeruginosaTwitching Motility: Type IV Pili in Action

(2012) Lori L. Burrows   Annual Review of Microbiology

Structure of PA1221, a Nonribosomal Peptide Synthetase Containing Adenylation and Peptidyl Carrier Protein Domains

(2012) Carter A. Mitchell et al.   BIOCHEMISTRY

Heterologous Expression and Structural Characterisation of a Pyrazinone Natural Product Assembly Line

(2012) Morgan A. Wyatt et al.   CHEMBIOCHEM

Structural and Functional Investigation of the Intermolecular Interaction between NRPS Adenylation and Carrier Protein Domains

(2012) Jesse A. Sundlov et al.   CHEMISTRY & BIOLOGY

Pyoverdine biosynthesis and secretion inPseudomonas aeruginosa: implications for metal homeostasis

(2012) Isabelle J. Schalk et al.   ENVIRONMENTAL MICROBIOLOGY

Hypervirulent Klebsiella pneumoniae: the next superbug?

(2012) Alyssa S Shon et al.   Future Microbiology

Role of Acinetobactin-Mediated Iron Acquisition Functions in the Interaction of Acinetobacter baumannii Strain ATCC 19606Twith Human Lung Epithelial Cells, Galleria mellonella Caterpillars, and Mice

(2012) Jennifer A. Gaddy et al.   INFECTION AND IMMUNITY

Comparative Analysis of the First Complete Enterococcus faecium Genome

(2012) M. M. C. Lam et al.   JOURNAL OF BACTERIOLOGY

Structural Basis of the Interaction of MbtH-like Proteins, Putative Regulators of Nonribosomal Peptide Biosynthesis, with Adenylating Enzymes

(2012) Dominik A. Herbst et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The structural role of the carrier protein – active controller or passive carrier

(2012) John Crosby et al.   NATURAL PRODUCT REPORTS

A stand-alone adenylation domain forms amide bonds in streptothricin biosynthesis

(2012) Chitose Maruyama et al.   Nature Chemical Biology

Pseudomonas aeruginosa Overrides the Virulence Inducing Effect of Opioids When It Senses an Abundance of Phosphate

(2012) Alexander Zaborin et al.   PLoS One

The Acinetobacter baumannii entA Gene Located Outside the Acinetobactin Cluster Is Critical for Siderophore Production, Iron Acquisition and Virulence

(2012) William F. Penwell et al.   PLoS One

Phevalin (aureusimine B)Production by Staphylococcus aureus Biofilm and Impacts on Human Keratinocyte Gene Expression

(2012) Patrick R. Secor et al.   PLoS One

Nonprocessive [2 + 2]e- off-loading reductase domains from mycobacterial nonribosomal peptide synthetases

(2012) A. Chhabra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Strain-dependent diversity in the Pseudomonas aeruginosa quorum-sensing regulon

(2012) S. Chugani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ThePseudomonas aeruginosaantimetabolite L-2-amino-4-methoxy-trans-3-butenoic acid inhibits growth ofErwinia amylovoraand acts as a seed germination-arrest factor

(2012) Xiaoyun Lee et al.   Environmental Microbiology Reports

In Vivo-Validated Essential Genes Identified in Acinetobacter baumannii by Using Human Ascites Overlap Poorly with Essential Genes Detected on Laboratory Media

(2012) T. C. Umland et al.   mBio

Interaction of Lipocalin 2, Transferrin, and Siderophores Determines the Replicative Niche of Klebsiella pneumoniae during Pneumonia

(2012) M. A. Bachman et al.   mBio

Treatment of Klebsiella Pneumoniae Carbapenemase (KPC) infections: a review of published case series and case reports

(2012) Grace C Lee et al.   Annals of Clinical Microbiology and Antimicrobials

Unique Biofilm Signature, Drug Susceptibility and Decreased Virulence in Drosophila through the Pseudomonas aeruginosa Two-Component System PprAB

(2012) Sophie de Bentzmann et al.   PLoS Pathogens

Structural Characterization and High-Throughput Screening of Inhibitors of PvdQ, an NTN Hydrolase Involved in Pyoverdine Synthesis

(2011) Eric J. Drake et al.   ACS Chemical Biology

Structural Basis for Phosphopantetheinyl Carrier Domain Interactions in the Terminal Module of Nonribosomal Peptide Synthetases

(2011) Ye Liu et al.   CHEMISTRY & BIOLOGY

Trends in antimicrobial resistance in intensive care units in the United States

(2011) Kavitha Prabaker et al.   Current Opinion in Critical Care

Biosynthesis of the pyoverdine siderophore ofPseudomonas aeruginosainvolves precursors with a myristic or a myristoleic acid chain

(2011) Mélissa Hannauer et al.   FEBS LETTERS

Adherence and motility characteristics of clinical Acinetobacter baumannii isolates

(2011) Bart A. Eijkelkamp et al.   FEMS MICROBIOLOGY LETTERS

Klebsiella pneumoniae Yersiniabactin Promotes Respiratory Tract Infection through Evasion of Lipocalin 2

(2011) Michael A. Bachman et al.   INFECTION AND IMMUNITY

Genetic basis of antibiotic resistance in pathogenic Acinetobacter species

(2011) Laurent Poirel et al.   IUBMB LIFE

ClbP Is a Prototype of a Peptidase Subgroup Involved in Biosynthesis of Nonribosomal Peptides

(2011) Damien Dubois et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Function of MbtH homologs in nonribosomal peptide biosynthesis and applications in secondary metabolite discovery

(2011) Richard H. Baltz   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Genetic analysis of surface motility in Acinetobacter baumannii

(2011) K. M. Clemmer et al.   MICROBIOLOGY-SGM

A Novel Metagenomic Short-Chain Dehydrogenase/Reductase Attenuates Pseudomonas aeruginosa Biofilm Formation and Virulence on Caenorhabditis elegans

(2011) Patrick Bijtenhoorn et al.   PLoS One

Pseudomonas Aeruginosa: Resistance to the Max

(2011) Keith Poole   Frontiers in Microbiology

Iron uptake and metabolism in pseudomonads

(2010) Pierre Cornelis   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Activation of the Pacidamycin PacL Adenylation Domain by MbtH-like Proteins

(2010) Wenjun Zhang et al.   BIOCHEMISTRY

Biochemical and Structural Characterization of Bisubstrate Inhibitors of BasE, the Self-Standing Nonribosomal Peptide Synthetase Adenylate-Forming Enzyme of Acinetobactin Synthesis,

(2010) Eric J. Drake et al.   BIOCHEMISTRY

MbtH-Like Proteins as Integral Components of Bacterial Nonribosomal Peptide Synthetases

(2010) Elizabeth A. Felnagle et al.   BIOCHEMISTRY

Pyrosequencing-based comparative genome analysis of the nosocomial pathogen Enterococcus faecium and identification of a large transferable pathogenicity island

(2010) Willem van Schaik et al.   BMC GENOMICS

Prevalence of multidrug-resistant organisms recovered at a military burn center

(2010) Edward F. Keen et al.   BURNS

A Family of Pyrazinone Natural Products from a Conserved Nonribosomal Peptide Synthetase in Staphylococcus aureus

(2010) Michael Zimmermann et al.   CHEMISTRY & BIOLOGY

Nonribosomal peptide synthetases: structures and dynamics

(2010) Matthias Strieker et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Identification of the Biosynthetic Gene Cluster for the Pseudomonas aeruginosa Antimetabolite L-2-Amino-4-Methoxy-trans-3-Butenoic Acid

(2010) X. Lee et al.   JOURNAL OF BACTERIOLOGY

Complete Genome Sequence of Enterobacter cloacae subsp. cloacae Type Strain ATCC 13047

(2010) Y. Ren et al.   JOURNAL OF BACTERIOLOGY

Crystal Structure of Escherichia coli Enterobactin-specific Isochorismate Synthase (EntC) Bound to its Reaction Product Isochorismate: Implications for the Enzyme Mechanism and Differential Activity of Chorismate-utilizing Enzymes

(2010) Sudharsan Sridharan et al.   JOURNAL OF MOLECULAR BIOLOGY

Biosynthesis of HSAF, a Tetramic Acid-Containing Macrolactam from Lysobacter enzymogenes

(2010) Lili Lou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Aureusimines in Staphylococcus aureus Are Not Involved in Virulence

(2010) Fei Sun et al.   PLoS One

Common biosynthetic origins for polycyclic tetramate macrolactams from phylogenetically diverse bacteria

(2010) J. A. V. Blodgett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of the biosynthetic gene cluster for the pacidamycin group of peptidyl nucleoside antibiotics

(2010) W. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Staphylococcus aureus Nonribosomal Peptide Secondary Metabolites Regulate Virulence

(2010) M. A. Wyatt et al.   SCIENCE

Conformational Dynamics in the Acyl-CoA Synthetases, Adenylation Domains of Non-ribosomal Peptide Synthetases, and Firefly Luciferase

(2009) Andrew M. Gulick   ACS Chemical Biology

Synthesis of the siderophore pyoverdine in Pseudomonas aeruginosa involves a periplasmic maturation

(2009) Emilie Yeterian et al.   AMINO ACIDS

Salmochelin, the long-overlooked catecholate siderophore of Salmonella

(2009) Silke I. Müller et al.   BIOMETALS

Genetic Structure and Distribution of the Colibactin Genomic Island among Members of the Family Enterobacteriaceae

(2009) J. Putze et al.   INFECTION AND IMMUNITY

Three Siderophores from One Bacterial Enzymatic Assembly Line

(2009) William M. Wuest et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Genome-scale metabolic network analysis and drug targeting of multi-drug resistant pathogen Acinetobacter baumannii AYE

(2009) Hyun Uk Kim et al.   Molecular BioSystems

Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America

(2008) Helen W. Boucher et al.   CLINICAL INFECTIOUS DISEASES

Acinetobacter baumannii: Emergence of a Successful Pathogen

(2008) A. Y. Peleg et al.   CLINICAL MICROBIOLOGY REVIEWS

Multidrug-resistant Organisms in Military Wounds from Iraq and Afghanistan

(2008) Jason H. Calhoun et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Comparative Genome Sequence Analysis of Multidrug-Resistant Acinetobacter baumannii

(2008) M. D. Adams et al.   JOURNAL OF BACTERIOLOGY

Federal Funding for the Study of Antimicrobial Resistance in Nosocomial Pathogens: No ESKAPE

(2008) Louis B. Rice   JOURNAL OF INFECTIOUS DISEASES

A Latent Oxazoline Electrophile for N−O−C Bond Formation in Pseudomonine Biosynthesis

(2008) Elizabeth S. Sattely et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Current control and treatment of multidrug-resistant Acinetobacter baumannii infections

(2008) Drosos E Karageorgopoulos et al.   LANCET INFECTIOUS DISEASES

Dynamic thiolation–thioesterase structure of a non-ribosomal peptide synthetase

(2008) Dominique P. Frueh et al.   NATURE

Genomic Diversity within the Enterobacter cloacae Complex

(2008) Armand Paauw et al.   PLoS One

Crystal Structure of the Termination Module of a Nonribosomal Peptide Synthetase

(2008) A. Tanovic et al.   SCIENCE