β-Lactam formation by a non-ribosomal peptide synthetase during antibiotic biosynthesis

Epimerization and substrate gating by a TE domain in β-lactam antibiotic biosynthesis

(2014) Nicole M Gaudelli et al.   Nature Chemical Biology

Nonproteinogenic Amino Acid Building Blocks for Nonribosomal Peptide and Hybrid Polyketide Scaffolds

(2013) Christopher T. Walsh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Origins of the β-lactam rings in natural products

(2013) Kapil Tahlan et al.   JOURNAL OF ANTIBIOTICS

Non-ribosomal Propeptide Precursor in Nocardicin A Biosynthesis Predicted from Adenylation Domain Specificity Dependent on the MbtH Family Protein NocI

(2013) Jeanne M. Davidsen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Antibiotic resistance: The last resort

(2013) Maryn McKenna   NATURE

Intrinsic evolutionary constraints on protease structure, enzyme acylation, and the identity of the catalytic triad

(2013) A. R. Buller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In Vivo Characterization of Nonribosomal Peptide Synthetases NocA and NocB in the Biosynthesis of Nocardicin A

(2012) Jeanne M. Davidsen et al.   CHEMISTRY & BIOLOGY

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature

(2012) Paul G. Arnison et al.   NATURAL PRODUCT REPORTS

Monocyclic β-Lactams: New Structures for New Biological Activities

(2011) P. Galletti et al.   CURRENT MEDICINAL CHEMISTRY

NRPSpredictor2—a web server for predicting NRPS adenylation domain specificity

(2011) Marc Röttig et al.   NUCLEIC ACIDS RESEARCH

The antibiotics market

(2010) Bashar Hamad   NATURE REVIEWS DRUG DISCOVERY

Has the era of untreatable infections arrived?

(2009) D. M. Livermore   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Antibiotics: Natural products essential to human health

(2009) Arnold L. Demain   MEDICINAL RESEARCH REVIEWS

A Latent Oxazoline Electrophile for N−O−C Bond Formation in Pseudomonine Biosynthesis

(2008) Elizabeth S. Sattely et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Four enzymes define the incorporation of coenzyme A in thienamycin biosynthesis

(2008) M. F. Freeman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA