X-Ray Crystallography and Electron Microscopy of Cross- and Multi-Module Nonribosomal Peptide Synthetase Proteins Reveal a Flexible Architecture

Published 2017 View Full Article

Authors

Keywords

nonribosomal peptide synthetase, NRPS, mega-enzyme, synthetic cycle, MbtH-like protein, adenosine-vinylsulfonamide inhibitor, adenylation activity, conformational flexibility, single-particle electron microscopy, X-ray crystallography

Journal

STRUCTURE

Volume 25, Issue 5, Pages 783-793.e4

Publisher

Elsevier BV

Online

2017-04-21

DOI

10.1016/j.str.2017.03.014

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