New advances in probing cell–extracellular matrix interactions

Optogenetic control of cellular forces and mechanotransduction

(2017) Léo Valon et al.   Nature Communications

Programming Molecular Association and Viscoelastic Behavior in Protein Networks

(2016) Lawrence J. Dooling et al.   ADVANCED MATERIALS

Understanding the Role of ECM Protein Composition and Geometric Micropatterning for Engineering Human Skeletal Muscle

(2016) Rebecca M. Duffy et al.   ANNALS OF BIOMEDICAL ENGINEERING

Mechanical Control of Epithelial-to-Mesenchymal Transitions in Development and Cancer

(2016) Laralynne Przybyla et al.   Annual Review of Cell and Developmental Biology

Dimensionality and spreading influence MSC YAP/TAZ signaling in hydrogel environments

(2016) Steven R. Caliari et al.   BIOMATERIALS

Biophysical Tools for Cellular and Subcellular Mechanical Actuation of Cell Signaling

(2016) Allen P. Liu   BIOPHYSICAL JOURNAL

Viscoplasticity Enables Mechanical Remodeling of Matrix by Cells

(2016) Sungmin Nam et al.   BIOPHYSICAL JOURNAL

Extracellular Matrix Stiffening Induces a Malignant Phenotypic Transition in Breast Epithelial Cells

(2016) Ryan S. Stowers et al.   Cellular and Molecular Bioengineering

Synthesis of Binary Nanopatterns on Hydrogels for Initiating Cellular Responses

(2016) Judith Guasch et al.   CHEMISTRY OF MATERIALS

Quantitative Multiscale Cell Imaging in Controlled 3D Microenvironments

(2016) Erik S. Welf et al.   DEVELOPMENTAL CELL

For whom the cells pull: Hydrogel and micropost devices for measuring traction forces

(2016) Alexandre J.S. Ribeiro et al.   METHODS

Micropost arrays for measuring stem cell-derived cardiomyocyte contractility

(2016) Kevin M. Beussman et al.   METHODS

Mechanical confinement triggers glioma linear migration dependent on formin FHOD3

(2016) Pascale Monzo et al.   MOLECULAR BIOLOGY OF THE CELL

Mimicking biological functionality with polymers for biomedical applications

(2016) Jordan J. Green et al.   NATURE

Mechanosensitive subcellular rheostasis drives emergent single-cell mechanical homeostasis

(2016) Shinuo Weng et al.   NATURE MATERIALS

Transcription upregulation via force-induced direct stretching of chromatin

(2016) Arash Tajik et al.   NATURE MATERIALS

Interfacial geometry dictates cancer cell tumorigenicity

(2016) Junmin Lee et al.   NATURE MATERIALS

Measuring cell-generated forces: a guide to the available tools

(2016) William J Polacheck et al.   NATURE METHODS

Fast volumetric calcium imaging across multiple cortical layers using sculpted light

(2016) Robert Prevedel et al.   NATURE METHODS

A practical guide to hydrogels for cell culture

(2016) Steven R Caliari et al.   NATURE METHODS

Matrix mechanics controls FHL2 movement to the nucleus to activate p21 expression

(2016) Naotaka Nakazawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Strain-enhanced stress relaxation impacts nonlinear elasticity in collagen gels

(2016) Sungmin Nam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death

(2016) M. Raab et al.   SCIENCE

Nuclear envelope rupture and repair during cancer cell migration

(2016) C. M. Denais et al.   SCIENCE

Click-Crosslinked Injectable Gelatin Hydrogels

(2016) Sandeep T. Koshy et al.   Advanced Healthcare Materials

In vivo super-resolution RESOLFT microscopy of Drosophila melanogaster

(2016) Sebastian Schnorrenberg et al.   eLife

The design of reversible hydrogels to capture extracellular matrix dynamics

(2016) Adrianne M. Rosales et al.   Nature Reviews Materials

Microscale spatial heterogeneity of protein structural transitions in fibrin matrices

(2016) F. Fleissner et al.   Science Advances

Microfluidic device for the formation of optically excitable, three-dimensional, compartmentalized motor units

(2016) S. G. M. Uzel et al.   Science Advances

Cell-cell contact and matrix adhesion promote αSMA expression during TGFβ1-induced epithelial-myofibroblast transition via Notch and MRTF-A

(2016) Joseph W. O’Connor et al.   Scientific Reports

Mechanically activated artificial cell by using microfluidics

(2016) Kenneth K. Y. Ho et al.   Scientific Reports

Adaptable Hydrogel Networks with Reversible Linkages for Tissue Engineering

(2015) Huiyuan Wang et al.   ADVANCED MATERIALS

Molecular-Scale Tools for Studying Mechanotransduction

(2015) Andrew S. LaCroix et al.   Annual Review of Biomedical Engineering

Controlled surface topography regulates collective 3D migration by epithelial–mesenchymal composite embryonic tissues

(2015) Jiho Song et al.   BIOMATERIALS

Versatile click alginate hydrogels crosslinked via tetrazine–norbornene chemistry

(2015) Rajiv M. Desai et al.   BIOMATERIALS

Deconvolution-free Subcellular Imaging with Axially Swept Light Sheet Microscopy

(2015) Kevin M. Dean et al.   BIOPHYSICAL JOURNAL

Platelet geometry sensing spatially regulates  -granule secretion to enable matrix self-deposition

(2015) Y. Sakurai et al.   BLOOD

Cortical Contractility Triggers a Stochastic Switch to Fast Amoeboid Cell Motility

(2015) Verena Ruprecht et al.   CELL

Confinement and Low Adhesion Induce Fast Amoeboid Migration of Slow Mesenchymal Cells

(2015) Yan-Jun Liu et al.   CELL

Microfluidic 3D cell culture: from tools to tissue models

(2015) Vincent van Duinen et al.   CURRENT OPINION IN BIOTECHNOLOGY

Cell spreading area regulates clathrin-coated pit dynamics on micropatterned substrate

(2015) Xinyu Tan et al.   Integrative Biology

Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration

(2015) I. Acerbi et al.   Integrative Biology

A microfluidic pipette array for mechanophenotyping of cancer cells and mechanical gating of mechanosensitive channels

(2015) Lap Man Lee et al.   LAB ON A CHIP

Spatial distribution of cell–cell and cell–ECM adhesions regulates force balance while main­taining E-cadherin molecular tension in cell pairs

(2015) Joo Yong Sim et al.   MOLECULAR BIOLOGY OF THE CELL

Cellular chirality arising from the self-organization of the actin cytoskeleton

(2015) Yee Han Tee et al.   NATURE CELL BIOLOGY

Tropomyosin controls sarcomere-like contractions for rigidity sensing and suppressing growth on soft matrices

(2015) Haguy Wolfenson et al.   NATURE CELL BIOLOGY

Cell-mediated fibre recruitment drives extracellular matrix mechanosensing in engineered fibrillar microenvironments

(2015) Brendon M. Baker et al.   NATURE MATERIALS

Stress-stiffening-mediated stem-cell commitment switch in soft responsive hydrogels

(2015) Rajat K. Das et al.   NATURE MATERIALS

A photoreversible protein-patterning approach for guiding stem cell fate in three-dimensional gels

(2015) Cole A. DeForest et al.   NATURE MATERIALS

Hydrogels with tunable stress relaxation regulate stem cell fate and activity

(2015) Ovijit Chaudhuri et al.   NATURE MATERIALS

Tissue matrix arrays for high-throughput screening and systems analysis of cell function

(2015) Vince Z Beachley et al.   NATURE METHODS

Chemically sensitive bioimaging with coherent Raman scattering

(2015) Charles H. Camp Jr et al.   Nature Photonics

Forcing cells into shape: the mechanics of actomyosin contractility

(2015) Michael Murrell et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Beam scanning for rapid coherent Raman hyperspectral imaging

(2015) Ian Seungwan Ryu et al.   OPTICS LETTERS

Contractility of single cardiomyocytes differentiated from pluripotent stem cells depends on physiological shape and substrate stiffness

(2015) Alexandre J. S. Ribeiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gap geometry dictates epithelial closure efficiency

(2015) Andrea Ravasio et al.   Nature Communications

Structured line illumination Raman microscopy

(2015) Kozue Watanabe et al.   Nature Communications

Substrate stress relaxation regulates cell spreading

(2015) Ovijit Chaudhuri et al.   Nature Communications

Single-cell Migration Chip for Chemotaxis-based Microfluidic Selection of Heterogeneous Cell Populations

(2015) Yu-Chih Chen et al.   Scientific Reports

Microsecond scale vibrational spectroscopic imaging by multiplex stimulated Raman scattering microscopy

(2015) Chien-Sheng Liao et al.   Light-Science & Applications

Correlative Stochastic Optical Reconstruction Microscopy and Electron Microscopy

(2015) Doory Kim et al.   PLoS One

Biophysical Regulation of Chromatin Architecture Instills a Mechanical Memory in Mesenchymal Stem Cells

(2015) Su-Jin Heo et al.   Scientific Reports

Nanoscale Integrin Ligand Patterns Determine Melanoma Cell Behavior

(2014) Katharina Amschler et al.   ACS Nano

Influence of the stiffness of three-dimensional alginate/collagen-I interpenetrating networks on fibroblast biology

(2014) Cristiana Branco da Cunha et al.   BIOMATERIALS

Measuring stem cell dimensionality in tissue scaffolds

(2014) Tanya M. Farooque et al.   BIOMATERIALS

Use it or lose it: multiscale skeletal muscle adaptation to mechanical stimuli

(2014) Katrina M. Wisdom et al.   Biomechanics and Modeling in Mechanobiology

Geometry Regulates Traction Stresses in Adherent Cells

(2014) Patrick W. Oakes et al.   BIOPHYSICAL JOURNAL

Water Permeation Drives Tumor Cell Migration in Confined Microenvironments

(2014) Kimberly M. Stroka et al.   CELL

Stress Sensitivity and Mechanotransduction during Heart Development

(2014) Stephanie Majkut et al.   CURRENT BIOLOGY

Global architecture of the F-actin cytoskeleton regulates cell shape-dependent endothelial mechanotransduction

(2014) Yue Shao et al.   Integrative Biology

Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival

(2014) Takamasa Harada et al.   JOURNAL OF CELL BIOLOGY

Controlling cell geometry on substrates of variable stiffness can tune the degree of osteogenesis in human mesenchymal stem cells

(2014) Junmin Lee et al.   Journal of the Mechanical Behavior of Biomedical Materials

High-precision robotic microcontact printing (R-μCP) utilizing a vision guided selectively compliant articulated robotic arm

(2014) Jason D. McNulty et al.   LAB ON A CHIP

Extracellular matrix stiffness and composition jointly regulate the induction of malignant phenotypes in mammary epithelium

(2014) Ovijit Chaudhuri et al.   NATURE MATERIALS

Light-triggered in vivo activation of adhesive peptides regulates cell adhesion, inflammation and vascularization of biomaterials

(2014) Ted T. Lee et al.   NATURE MATERIALS

Materials as stem cell regulators

(2014) William L. Murphy et al.   NATURE MATERIALS

Mechanical memory and dosing influence stem cell fate

(2014) Chun Yang et al.   NATURE MATERIALS

A DNA-based molecular probe for optically reporting cellular traction forces

(2014) Brandon L Blakely et al.   NATURE METHODS

Correlative super-resolution fluorescence and metal-replica transmission electron microscopy

(2014) Kem A Sochacki et al.   NATURE METHODS

High-speed coherent Raman fingerprint imaging of biological tissues

(2014) Charles H. Camp Jr et al.   Nature Photonics

Mechanotransduction and extracellular matrix homeostasis

(2014) Jay D. Humphrey et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Extracellular matrix assembly: a multiscale deconstruction

(2014) Janna K. Mouw et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lattice light-sheet microscopy: Imaging molecules to embryos at high spatiotemporal resolution

(2014) Bi-Chang Chen et al.   SCIENCE

DNA-based digital tension probes reveal integrin forces during early cell adhesion

(2014) Yun Zhang et al.   Nature Communications

Designing ECM-mimetic materials using protein engineering

(2013) Lei Cai et al.   Acta Biomaterialia

Hyaluronan: A simple polysaccharide with diverse biological functions

(2013) Kevin T. Dicker et al.   Acta Biomaterialia

Micropatterning Alginate Substrates for In Vitro Cardiovascular Muscle on a Chip

(2013) Ashutosh Agarwal et al.   ADVANCED FUNCTIONAL MATERIALS

Photo-crosslinkable PEG-Based Microribbons for Forming 3D Macroporous Scaffolds with Decoupled Niche Properties

(2013) Li-Hsin Han et al.   ADVANCED MATERIALS

Biophysically Defined and Cytocompatible Covalently Adaptable Networks as Viscoelastic 3D Cell Culture Systems

(2013) Daniel D. McKinnon et al.   ADVANCED MATERIALS

The independent roles of mechanical, structural and adhesion characteristics of 3D hydrogels on the regulation of cancer invasion and dissemination

(2013) Jennifer N. Beck et al.   BIOMATERIALS

Mechanosensing through focal adhesion-anchored intermediate filaments

(2013) Martin Gregor et al.   FASEB JOURNAL

Guidance of collective cell migration by substrate geometry

(2013) Kevin Doxzen et al.   Integrative Biology

Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force

(2013) Katarina Wolf et al.   JOURNAL OF CELL BIOLOGY

Long-term live cell microscopy studies of lipid droplet fusion dynamics in adipocytes

(2013) Christian Jüngst et al.   JOURNAL OF LIPID RESEARCH

Epithelial mechanobiology, skin wound healing, and the stem cell niche

(2013) Nicholas D. Evans et al.   Journal of the Mechanical Behavior of Biomedical Materials

Microfluidic platforms for mechanobiology

(2013) William J. Polacheck et al.   LAB ON A CHIP

Molecular Tension Sensors Report Forces Generated by Single Integrin Molecules in Living Cells

(2013) Masatoshi Morimatsu et al.   NANO LETTERS

Chemical mapping of a single molecule by plasmon-enhanced Raman scattering

(2013) R. Zhang et al.   NATURE

Spatially isotropic four-dimensional imaging with dual-view plane illumination microscopy

(2013) Yicong Wu et al.   NATURE BIOTECHNOLOGY

Degradation-mediated cellular traction directs stem cell fate in covalently crosslinked three-dimensional hydrogels

(2013) Sudhir Khetan et al.   NATURE MATERIALS

In situ cell manipulation through enzymatic hydrogel photopatterning

(2013) Katarzyna A. Mosiewicz et al.   NATURE MATERIALS

Epithelial bridges maintain tissue integrity during collective cell migration

(2013) Sri Ram Krishna Vedula et al.   NATURE MATERIALS

Instant super-resolution imaging in live cells and embryos via analog image processing

(2013) Andrew G York et al.   NATURE METHODS

Light-Sheet Confined Super-Resolution Using Two-Photon Photoactivation

(2013) Francesca Cella Zanacchi et al.   PLoS One

Modulation of macrophage phenotype by cell shape

(2013) F. Y. McWhorter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Uniaxial cell stretching device for live-cell imaging of mechanosensitive cellular functions

(2013) Yue Shao et al.   REVIEW OF SCIENTIFIC INSTRUMENTS

Defining Single Molecular Forces Required to Activate Integrin and Notch Signaling

(2013) X. Wang et al.   SCIENCE

Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation

(2013) J. Swift et al.   SCIENCE

Quantitative, Label-Free Characterization of Stem Cell Differentiation at the Single-Cell Level by Broadband Coherent Anti-Stokes Raman Scattering Microscopy

(2013) Young Jong Lee et al.   TISSUE ENGINEERING PART C-METHODS

Rapid Prototyping of Concave Microwells for the Formation of 3D Multicellular Cancer Aggregates for Drug Screening

(2013) Ting-Yuan Tu et al.   Advanced Healthcare Materials

Nanotopography Influences Adhesion, Spreading, and Self-Renewal of Human Embryonic Stem Cells

(2012) Weiqiang Chen et al.   ACS Nano

Line-scanning Raman imaging spectroscopy for detection of fingerprints

(2012) Sunan Deng et al.   APPLIED OPTICS

Decoupling Substrate Stiffness, Spread Area, and Micropost Density: A Close Spatial Relationship between Traction Forces and Focal Adhesions

(2012) Sangyoon J. Han et al.   BIOPHYSICAL JOURNAL

Nanopatterning reveals an ECM area threshold for focal adhesion assembly and force transmission that is regulated by integrin activation and cytoskeleton tension

(2012) S. R. Coyer et al.   JOURNAL OF CELL SCIENCE

Advances in high-resolution imaging - techniques for three-dimensional imaging of cellular structures

(2012) D. S. Lidke et al.   JOURNAL OF CELL SCIENCE

Protein Secondary Structure Imaging with Ultrabroadband Multiplex Coherent Anti-Stokes Raman Scattering (CARS) Microspectroscopy

(2012) Kotatsu Bito et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Faster than the Speed of Hearing: Nanomechanical Force Probes Enable the Electromechanical Observation of Cochlear Hair Cells

(2012) Joseph C. Doll et al.   NANO LETTERS

Extracellular-matrix tethering regulates stem-cell fate

(2012) Britta Trappmann et al.   NATURE MATERIALS

Resolution doubling in live, multicellular organisms via multifocal structured illumination microscopy

(2012) Andrew G York et al.   NATURE METHODS

Second harmonic generation microscopy for quantitative analysis of collagen fibrillar structure

(2012) Xiyi Chen et al.   Nature Protocols

Chemotaxis of Cell Populations through Confined Spaces at Single-Cell Resolution

(2012) ZiQiu Tong et al.   PLoS One

Cellular Traction Stresses Increase with Increasing Metastatic Potential

(2012) Casey M. Kraning-Rush et al.   PLoS One

Actin filament curvature biases branching direction

(2012) V. I. Risca et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence of a large-scale mechanosensing mechanism for cellular adaptation to substrate stiffness

(2012) L. Trichet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function

(2012) I. K. Zervantonakis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stiffening hydrogels to probe short- and long-term cellular responses to dynamic mechanics

(2012) Murat Guvendiren et al.   Nature Communications

Hyaluronic Acid Hydrogels for Biomedical Applications

(2011) Jason A. Burdick et al.   ADVANCED MATERIALS

Diels−Alder Click Cross-Linked Hyaluronic Acid Hydrogels for Tissue Engineering

(2011) Chelsea M. Nimmo et al.   BIOMACROMOLECULES

Evolving the use of peptides as components of biomaterials

(2011) Joel H. Collier et al.   BIOMATERIALS

Elucidating the mechanobiology of malignant brain tumors using a brain matrix-mimetic hyaluronic acid hydrogel platform

(2011) Badriprasad Ananthanarayanan et al.   BIOMATERIALS

The influence of substrate creep on mesenchymal stem cell behaviour and phenotype

(2011) Andrew. R. Cameron et al.   BIOMATERIALS

The determination of stem cell fate by 3D scaffold structures through the control of cell shape

(2011) Girish Kumar et al.   BIOMATERIALS

An overview of tissue and whole organ decellularization processes

(2011) Peter M. Crapo et al.   BIOMATERIALS

Spatiotemporal Constraints on the Force-Dependent Growth of Focal Adhesions

(2011) Jonathan Stricker et al.   BIOPHYSICAL JOURNAL

Cell Shape and Substrate Rigidity Both Regulate Cell Stiffness

(2011) Shang-You Tee et al.   BIOPHYSICAL JOURNAL

Self-assembling peptide scaffolds for regenerative medicine

(2011) John B. Matson et al.   CHEMICAL COMMUNICATIONS

Vascular smooth muscle contractility depends on cell shape

(2011) Patrick W. Alford et al.   Integrative Biology

Subcellular spatial segregation of integrin subtypes by patterned multicomponent surfaces

(2011) Ravi A. Desai et al.   Integrative Biology

Stretching skin: The physiological limit and beyond

(2011) Adrián Buganza Tepole et al.   INTERNATIONAL JOURNAL OF NON-LINEAR MECHANICS

Magnetic micropillars as a tool to govern substrate deformations

(2011) Jimmy le Digabel et al.   LAB ON A CHIP

Mechanical strain in actin networks regulates FilGAP and integrin binding to filamin A

(2011) A. J. Ehrlicher et al.   NATURE

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Chemical contrast for imaging living systems: molecular vibrations drive CARS microscopy

(2011) John Paul Pezacki et al.   Nature Chemical Biology

Focal adhesion kinase links mechanical force to skin fibrosis via inflammatory signaling

(2011) Victor W Wong et al.   NATURE MEDICINE

Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives

(2011) Jeng-Jiann Chiu et al.   PHYSIOLOGICAL REVIEWS

Microenvironmental Geometry Guides Platelet Adhesion and Spreading: A Quantitative Analysis at the Single Cell Level

(2011) Ashley Kita et al.   PLoS One

Mechanical stretch and shear flow induced reorganization and recruitment of fibronectin in fibroblasts

(2011) Robert L. Steward et al.   Scientific Reports

High-throughput 3D spheroid culture and drug testing using a 384 hanging drop array

(2010) Yi-Chung Tung et al.   ANALYST

Modulus-driven differentiation of marrow stromal cells in 3D scaffolds that is independent of myosin-based cytoskeletal tension

(2010) Sapun H. Parekh et al.   BIOMATERIALS

Ultra-rapid activation of TRPV4 ion channels by mechanical forces applied to cell surface β1 integrins

(2010) Benjamin D. Matthews et al.   Integrative Biology

Endogenous patterns of mechanical stress are required for branching morphogenesis

(2010) Nikolce Gjorevski et al.   Integrative Biology

Platelet retraction force measurements using flexible post force sensors

(2010) Xin M. Liang et al.   LAB ON A CHIP

Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics

(2010) Carsten Grashoff et al.   NATURE

Nanoscale architecture of integrin-based cell adhesions

(2010) Pakorn Kanchanawong et al.   NATURE

Mechanics and contraction dynamics of single platelets and implications for clot stiffening

(2010) Wilbur A. Lam et al.   NATURE MATERIALS

Harnessing traction-mediated manipulation of the cell/matrix interface to control stem-cell fate

(2010) Nathaniel Huebsch et al.   NATURE MATERIALS

Measurement of mechanical tractions exerted by cells in three-dimensional matrices

(2010) Wesley R Legant et al.   NATURE METHODS

Mechanical regulation of cell function with geometrically modulated elastomeric substrates

(2010) Jianping Fu et al.   NATURE METHODS

Image Scanning Microscopy

(2010) Claus B. Müller et al.   PHYSICAL REVIEW LETTERS

Geometric cues for directing the differentiation of mesenchymal stem cells

(2010) K. A. Kilian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reconstituting Organ-Level Lung Functions on a Chip

(2010) D. Huh et al.   SCIENCE

Raman Spectroscopy and Related Techniques in Biomedicine

(2010) Andrew Downes et al.   SENSORS

Dynamic Hydrogels: Switching of 3D Microenvironments Using Two-Component Naturally Derived Extracellular Matrices

(2009) Brian M. Gillette et al.   ADVANCED MATERIALS

Label-Free Separation of Human Embryonic Stem Cells and Their Cardiac Derivatives Using Raman Spectroscopy

(2009) James W. Chan et al.   ANALYTICAL CHEMISTRY

Photocrosslinked alginate hydrogels with tunable biodegradation rates and mechanical properties

(2009) Oju Jeon et al.   BIOMATERIALS

Probing cellular mechanobiology in three-dimensional culture with collagen–agarose matrices

(2009) Theresa A. Ulrich et al.   BIOMATERIALS

Nanotopography-induced changes in focal adhesions, cytoskeletal organization, and mechanical properties of human mesenchymal stem cells

(2009) Evelyn K.F. Yim et al.   BIOMATERIALS

Global and Local Regulation of Clathrin-Coated Pit Dynamics Detected on Patterned Substrates

(2009) Allen P. Liu et al.   BIOPHYSICAL JOURNAL

Elastic Moduli of Collagen Gels Can Be Predicted from Two-Dimensional Confocal Microscopy

(2009) Ya-li Yang et al.   BIOPHYSICAL JOURNAL

Mechanics, malignancy, and metastasis: The force journey of a tumor cell

(2009) Sanjay Kumar et al.   CANCER AND METASTASIS REVIEWS

The extracellular matrix in development and morphogenesis: A dynamic view

(2009) Tania Rozario et al.   DEVELOPMENTAL BIOLOGY

Sequential click reactions for synthesizing and patterning three-dimensional cell microenvironments

(2009) Cole A. DeForest et al.   NATURE MATERIALS

Deep tissue multiphoton microscopy using longer wavelength excitation

(2009) Demirhan Kobat et al.   OPTICS EXPRESS

Optical visualization of Alzheimer’s pathology via multiphoton-excited intrinsic fluorescence and second harmonic generation

(2009) Alex C. Kwan et al.   OPTICS EXPRESS

Defining the role of syndecan-4 in mechanotransduction using surface-modification approaches

(2009) Robert M. Bellin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer cell angiogenic capability is regulated by 3D culture and integrin engagement

(2009) C. Fischbach et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytoskeleton-based forecasting of stem cell lineage fates

(2009) M. D. Treiser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fibronectin forms the most extensible biological fibers displaying switchable force-exposed cryptic binding sites

(2009) E. Klotzsch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interferometric fluorescent super-resolution microscopy resolves 3D cellular ultrastructure

(2009) G. Shtengel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Photodegradable Hydrogels for Dynamic Tuning of Physical and Chemical Properties

(2009) April M. Kloxin et al.   SCIENCE

Stretching Single Talin Rod Molecules Activates Vinculin Binding

(2009) A. del Rio et al.   SCIENCE

Coherent Anti-Stokes Raman Scattering Microscopy: Chemical Imaging for Biology and Medicine

(2008) Conor L. Evans et al.   Annual Review of Analytical Chemistry

Individually programmable cell stretching microwell arrays actuated by a Braille display

(2008) Yoko Kamotani et al.   BIOMATERIALS

Electrospinning: Applications in drug delivery and tissue engineering

(2008) Travis J. Sill et al.   BIOMATERIALS

The effect of photopolymerization on stem cells embedded in hydrogels

(2008) Natalja E. Fedorovich et al.   BIOMATERIALS

Raman spectroscopy and microscopy of individual cells and cellular components

(2008) J. Chan et al.   Laser & Photonics Reviews

Differentially oriented populations of actin filaments generated in lamellipodia collaborate in pushing and pausing at the cell front

(2008) Stefan A. Koestler et al.   NATURE CELL BIOLOGY

Mechanotransduction in development: a growing role for contractility

(2008) Michele A. Wozniak et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Neurosensory mechanotransduction

(2008) Martin Chalfie   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanotransduction in vascular physiology and atherogenesis

(2008) Cornelia Hahn et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

PEG Hydrogels for the Controlled Release of Biomolecules in Regenerative Medicine

(2008) Chien-Chi Lin et al.   PHARMACEUTICAL RESEARCH

Reconstruction of Zebrafish Early Embryonic Development by Scanned Light Sheet Microscopy

(2008) P. J. Keller et al.   SCIENCE

Subcellular curvature at the perimeter of micropatterned cells influences lamellipodial distribution and cell polarity

(2008) Jane James et al.   CELL MOTILITY AND THE CYTOSKELETON