A photoreversible protein-patterning approach for guiding stem cell fate in three-dimensional gels

Mechanical memory and dosing influence stem cell fate

(2014) Chun Yang et al.   NATURE MATERIALS

Synthesis of Photodegradable Macromers for Conjugation and Release of Bioactive Molecules

(2013) Donald R. Griffin et al.   BIOMACROMOLECULES

Photodegradable Supramolecular Hydrogels with Fluorescence Turn-On Reporter for Photomodulation of Cellular Microenvironments

(2013) Mingtao He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanical Properties and Degradation of Chain and Step-Polymerized Photodegradable Hydrogels

(2013) Mark W. Tibbitt et al.   MACROMOLECULES

Spatial organization within a niche as a determinant of stem-cell fate

(2013) Panteleimon Rompolas et al.   NATURE

Lighting the way

(2013) Daniel L. Alge et al.   NATURE MATERIALS

Degradation-mediated cellular traction directs stem cell fate in covalently crosslinked three-dimensional hydrogels

(2013) Sudhir Khetan et al.   NATURE MATERIALS

In situ cell manipulation through enzymatic hydrogel photopatterning

(2013) Katarzyna A. Mosiewicz et al.   NATURE MATERIALS

Photocontrolled Nanoparticles for On-Demand Release of Proteins

(2012) Malar A. Azagarsamy et al.   BIOMACROMOLECULES

Photodegradable Macromers and Hydrogels for Live Cell Encapsulation and Release

(2012) Donald R. Griffin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Materials science: Cell environments programmed with light

(2012) Matthias P. Lutolf   NATURE

Advances in Bioactive Hydrogels to Probe and Direct Cell Fate

(2012) Cole A. DeForest et al.   Annual Review of Chemical and Biomolecular Engineering

Moving from static to dynamic complexity in hydrogel design

(2012) Jason A. Burdick et al.   Nature Communications

Triggered Cell Release from Materials Using Bioadhesive Photocleavable Linkers

(2011) Melanie Wirkner et al.   ADVANCED MATERIALS

Photoreversible Patterning of Biomolecules within Click-Based Hydrogels

(2011) Cole A. DeForest et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

4-Aminophenylalanine as a Biocompatible Nucleophilic Catalyst for Hydrazone Ligations at Low Temperature and Neutral pH

(2011) Adam R. Blanden et al.   BIOCONJUGATE CHEMISTRY

Photodegradable, Photoadaptable Hydrogels via Radical-Mediated Disulfide Fragmentation Reaction

(2011) Benjamin D. Fairbanks et al.   MACROMOLECULES

Spatial and temporal control of the alkyne–azide cycloaddition by photoinitiated Cu(II) reduction

(2011) Brian J. Adzima et al.   Nature Chemistry

Cytocompatible click-based hydrogels with dynamically tunable properties through orthogonal photoconjugation and photocleavage reactions

(2011) Cole A. DeForest et al.   Nature Chemistry

Spatially controlled simultaneous patterning of multiple growth factors in three-dimensional hydrogels

(2011) Ryan G. Wylie et al.   NATURE MATERIALS

A mild, large-scale synthesis of 1,3-cyclooctanedione: expanding access to difluorinated cyclooctyne for copper-free click chemistry

(2011) Evan A. Sims et al.   TETRAHEDRON LETTERS

Enhanced proteolytic degradation of molecularly engineered PEG hydrogels in response to MMP-1 and MMP-2

(2010) J. Patterson et al.   BIOMATERIALS

Characterization of protein release from hydrolytically degradable poly(ethylene glycol) hydrogels

(2010) Silviya P. Zustiak et al.   BIOTECHNOLOGY AND BIOENGINEERING

Peptide-Functionalized Click Hydrogels with Independently Tunable Mechanics and Chemical Functionality for 3D Cell Culture

(2010) Cole A. DeForest et al.   CHEMISTRY OF MATERIALS

Harnessing traction-mediated manipulation of the cell/matrix interface to control stem-cell fate

(2010) Nathaniel Huebsch et al.   NATURE MATERIALS

Synthesis of photodegradable hydrogels as dynamically tunable cell culture platforms

(2010) April M Kloxin et al.   Nature Protocols

Functional PEG–peptide hydrogels to modulate local inflammation inducedby the pro-inflammatory cytokine TNFα

(2009) Chien-Chi Lin et al.   BIOMATERIALS

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

(2009) Raphael Kopan et al.   CELL

Aza-dibenzocyclooctynes for fast and efficient enzyme PEGylation via copper-free (3+2) cycloaddition

(2009) Marjoke F. Debets et al.   CHEMICAL COMMUNICATIONS

Light-Responsive Biomaterials: Development and Applications

(2009) Joshua S. Katz et al.   MACROMOLECULAR BIOSCIENCE

Designing materials to direct stem-cell fate

(2009) Matthias P. Lutolf et al.   NATURE

Sequential click reactions for synthesizing and patterning three-dimensional cell microenvironments

(2009) Cole A. DeForest et al.   NATURE MATERIALS

Photodegradable Hydrogels for Dynamic Tuning of Physical and Chemical Properties

(2009) April M. Kloxin et al.   SCIENCE

Visualizing Metabolically Labeled Glycoconjugates of Living Cells by Copper-Free and Fast Huisgen Cycloadditions

(2008) Xinghai Ning et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rapid Oxime and Hydrazone Ligations with Aromatic Aldehydes for Biomolecular Labeling

(2008) Anouk Dirksen et al.   BIOCONJUGATE CHEMISTRY

Intramolecular Sensitization of Photocleavage of the Photolabile 2-(2-Nitrophenyl)propoxycarbonyl (NPPOC) Protecting Group: Photoproducts and Photokinetics of the Release of Nucleosides

(2008) Dominik Wöll et al.   CHEMISTRY-A EUROPEAN JOURNAL

Second-Generation Difluorinated Cyclooctynes for Copper-Free Click Chemistry

(2008) Julian A. Codelli et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An Interfacial Oxime Reaction To Immobilize Ligands and Cells in Patterns and Gradients to Photoactive Surfaces

(2008) Sungjin Park et al.   LANGMUIR