Nonhuman Primates and Translational Research: Progress, Opportunities, and Challenges

Whole genome sequencing predicts novel human disease models in rhesus macaques

(2017) Benjamin N. Bimber et al.   GENOMICS

Nonhuman Primates and Translational Research—Cardiovascular Disease

(2017) Laura A Cox et al.   ILAR JOURNAL

Use and Importance of Nonhuman Primates in Metabolic Disease Research: Current State of the Field

(2017) Peter J Havel et al.   ILAR JOURNAL

Nonhuman Primate Models and Understanding the Pathogenesis of HIV Infection and AIDS

(2017) Ronald S Veazey et al.   ILAR JOURNAL

The Chimpanzee Model of Viral Hepatitis: Advances in Understanding the Immune Response and Treatment of Viral Hepatitis

(2017) Robert E Lanford et al.   ILAR JOURNAL

Genomic Tools for the Use of Nonhuman Primates in Translational Research

(2017) John D. Harding   ILAR JOURNAL

Nonhuman Primate Studies to Advance Vision Science and Prevent Blindness

(2017) Michael J Mustari   ILAR JOURNAL

Accelerating Biomedical Discoveries through Rigor and Transparency

(2017) Judith A. Hewitt et al.   ILAR JOURNAL

Naturally Occurring Nonhuman Primate Models of Psychosocial Processes

(2017) John P Capitanio   ILAR JOURNAL

Translational Research in the Nonhuman Primate Model of Tuberculosis

(2017) Taylor W Foreman et al.   ILAR JOURNAL

Laboratory Animal Laws, Regulations, Guidelines and Standards in China Mainland, Japan, and Korea

(2017) Bryan E Ogden et al.   ILAR JOURNAL

Comparison of the Canadian and US Laws, Regulations, Policies, and Systems of Oversight for Animals in Research

(2017) Gilly Griffin et al.   ILAR JOURNAL

Introduction: Global Laws, Regulations, and Standards for Animals in Research

(2017) Mary Ann Vasbinder et al.   ILAR JOURNAL

Protecting Animals and Enabling Research in the European Union: An Overview of Development and Implementation of Directive 2010/63/EU

(2017) I Anna S Olsson et al.   ILAR JOURNAL

Tackling HIV and AIDS: contributions by non-human primate models

(2017) Koen K A Van Rompay   LAB ANIMAL

In Retrospect: A decade of shared genomic associations

(2017) Teri A. Manolio   NATURE

Exome screening to identify loss-of-function mutations in the rhesus macaque for development of preclinical models of human disease

(2016) Adam S. Cornish et al.   BMC GENOMICS

Whole-genome characterization in pedigreed non-human primates using genotyping-by-sequencing (GBS) and imputation

(2016) Benjamin N. Bimber et al.   BMC GENOMICS

TALEN-based generation of a cynomolgus monkey disease model for human microcephaly

(2016) Qiong Ke et al.   CELL RESEARCH

The population genomics of rhesus macaques ( Macaca mulatta ) based on whole-genome sequences

(2016) Cheng Xue et al.   GENOME RESEARCH

Mouse Models for Drug Discovery. Can New Tools and Technology Improve Translational Power?

(2016) Aamir Zuberi et al.   ILAR JOURNAL

Drug Discovery in Fish, Flies, and Worms

(2016) Kevin Strange   ILAR JOURNAL

Genome editing in nonhuman primates: approach to generating human disease models

(2016) Y. Chen et al.   JOURNAL OF INTERNAL MEDICINE

The next step in translational research: lessons learned from the first preclinical randomized controlled trial

(2016) Gemma Llovera et al.   JOURNAL OF NEUROCHEMISTRY

Monkey kingdom

(2016) David Cyranoski   NATURE

Autism-like behaviours and germline transmission in transgenic monkeys overexpressing MeCP2

(2016) Zhen Liu et al.   NATURE

A rhesus macaque model of Asian-lineage Zika virus infection

(2016) Dawn M. Dudley et al.   Nature Communications

Generation of transgenic marmosets expressing genetically encoded calcium indicators

(2016) Jung Eun Park et al.   Scientific Reports

Biopharma CRO industry in China: landscape and opportunities

(2015) Christine Xia et al.   DRUG DISCOVERY TODAY

Functional disruption of the dystrophin gene in rhesus monkey using CRISPR/Cas9

(2015) Yongchang Chen et al.   HUMAN MOLECULAR GENETICS

Brains, Genes, and Primates

(2015) Juan Carlos Izpisua Belmonte et al.   NEURON

Prospects for genetically modified non-human primate models, including the common marmoset

(2015) Erika Sasaki   NEUROSCIENCE RESEARCH

Why primate models matter

(2014) Kimberley A. Phillips et al.   AMERICAN JOURNAL OF PRIMATOLOGY

Development and validation of a SNP-based assay for inferring the genetic ancestry of rhesus macaques (Macaca mulatta)

(2014) Sree Kanthaswamy et al.   AMERICAN JOURNAL OF PRIMATOLOGY

Marmosets are stars of Japan’s ambitious brain project

(2014) David Cyranoski   NATURE

Clinical development success rates for investigational drugs

(2014) Michael Hay et al.   NATURE BIOTECHNOLOGY

IACUC Review of Nonhuman Primate Research

(2013) S. D. Tardif et al.   ILAR JOURNAL

Baboons as a Model to Study Genetics and Epigenetics of Human Disease

(2013) L. A. Cox et al.   ILAR JOURNAL

Progress and Prospects for Genetic Modification of Nonhuman Primate Models in Biomedical Research

(2013) A. W. S. Chan   ILAR JOURNAL

Progress in Genetics and Genomics of Nonhuman Primates

(2013) J. D. Harding   ILAR JOURNAL

Phase II and Phase III attrition rates 2011–2012

(2013) John Arrowsmith et al.   NATURE REVIEWS DRUG DISCOVERY

Bringing genome-wide association findings into clinical use

(2013) Teri A. Manolio   NATURE REVIEWS GENETICS

Raise standards for preclinical cancer research

(2012) C. Glenn Begley et al.   NATURE

Believe it or not: how much can we rely on published data on potential drug targets?

(2011) Florian Prinz et al.   NATURE REVIEWS DRUG DISCOVERY

Defining Translational Research: Implications for Training

(2010) Doris McGartland Rubio et al.   ACADEMIC MEDICINE

Mitochondrial gene replacement in primate offspring and embryonic stem cells

(2009) Masahito Tachibana et al.   NATURE

Generation of transgenic non-human primates with germline transmission

(2009) Erika Sasaki et al.   NATURE

Contributions of non-human primates to neuroscience research

(2008) John P Capitanio et al.   LANCET