Mouse Models for Drug Discovery. Can New Tools and Technology Improve Translational Power?

Monoclonal Antibodies for Lipid Management

(2016) Matthew J. Feinstein et al.   Current Atherosclerosis Reports

Using the mouse to model human disease: increasing validity and reproducibility

(2016) Monica J. Justice et al.   Disease Models & Mechanisms

A comprehensive review of the neonatal Fc receptor and its application in drug delivery

(2016) João Pedro Martins et al.   PHARMACOLOGY & THERAPEUTICS

Collaborative Cross and Diversity Outbred data resources in the Mouse Phenome Database

(2015) Molly A. Bogue et al.   MAMMALIAN GENOME

Correction of Dystrophin Expression in Cells From Duchenne Muscular Dystrophy Patients Through Genomic Excision of Exon 51 by Zinc Finger Nucleases

(2015) David G Ousterout et al.   MOLECULAR THERAPY

WITHDRAWN—a resource for withdrawn and discontinued drugs

(2015) Vishal B. Siramshetty et al.   NUCLEIC ACIDS RESEARCH

A Mouse Geneticist's Practical Guide to CRISPR Applications

(2014) P. Singh et al.   GENETICS

Heritability and coefficient of genetic variation analyses of phenotypic traits provide strong basis for high-resolution QTL mapping in the Collaborative Cross mouse genetic reference population

(2014) Fuad A. Iraqi et al.   MAMMALIAN GENOME

Generation of targeted mouse mutants by embryo microinjection of TALENs

(2014) Benedikt Wefers et al.   METHODS

The new frontier of genome engineering with CRISPR-Cas9

(2014) J. A. Doudna et al.   SCIENCE

Application of human FcRn transgenic mice as a pharmacokinetic screening tool of monoclonal antibody

(2014) Kenta Haraya et al.   XENOBIOTICA

High-Resolution Genetic Mapping Using the Mouse Diversity Outbred Population

(2012) Karen L. Svenson et al.   GENETICS

Ten Years of the Collaborative Cross

(2012) David W. Threadgill et al.   GENETICS

The diversity outbred mouse population

(2012) Gary A. Churchill et al.   MAMMALIAN GENOME

Mouse genomic variation and its effect on phenotypes and gene regulation

(2011) Thomas M. Keane et al.   NATURE

A Single Ascending Dose Study of Bapineuzumab in Patients With Alzheimer Disease

(2010) Ronald S. Black et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Safety and Pharmacokinetics of Urtoxazumab, a Humanized Monoclonal Antibody, against Shiga-Like Toxin 2 in Healthy Adults and in Pediatric Patients Infected with Shiga-Like Toxin-Producing Escherichia coli

(2009) E. L. Lopez et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics

(2008) Elissa J. Chesler et al.   MAMMALIAN GENOME