Potential Therapies by Stem Cell-Derived Exosomes in CNS Diseases: Focusing on the Neurogenic Niche

Exosomes as new diagnostic tools in CNS diseases

(2016) Katja M. Kanninen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Emergence of exosomal miRNAs as a diagnostic biomarker for Alzheimer's disease

(2016) Vo Van Giau et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Grapefruit-derived Nanovectors Delivering Therapeutic miR17 Through an Intranasal Route Inhibit Brain Tumor Progression

(2016) Xiaoying Zhuang et al.   MOLECULAR THERAPY

Mesenchymal stem cell-derived exosomes from different sources selectively promote neuritic outgrowth

(2016) M.A. Lopez-Verrilli et al.   NEUROSCIENCE

Therapeutic strategies for Alzheimer's disease in clinical trials

(2016) Justyna Godyń et al.   Pharmacological Reports

Exosomes as Novel Regulators of Adult Neurogenic Niches

(2016) Luis Federico Bátiz et al.   Frontiers in Cellular Neuroscience

Characterization of Induced Pluripotent Stem Cell Microvesicle Genesis, Morphology and Pluripotent Content

(2016) Jing Zhou et al.   Scientific Reports

Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: A case-control study

(2015) Massimo S. Fiandaca et al.   Alzheimers & Dementia

Embryonic Origin of Postnatal Neural Stem Cells

(2015) Luis C. Fuentealba et al.   CELL

Embryonic Stem Cell-Derived Exosomes Promote Endogenous Repair Mechanisms and Enhance Cardiac Function Following Myocardial Infarction

(2015) M. Khan et al.   CIRCULATION RESEARCH

The current state of the neurogenic theory of depression and anxiety

(2015) Bradley R Miller et al.   CURRENT OPINION IN NEUROBIOLOGY

The clinical relevance of circulating, exosomal miRNAs as biomarkers for cancer

(2015) Heidi Schwarzenbach   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Exosomes as drug delivery vehicles for Parkinson's disease therapy

(2015) Matthew J. Haney et al.   JOURNAL OF CONTROLLED RELEASE

The Role of Circulating Platelets Microparticles and Platelet Parameters in Acute Ischemic Stroke Patients

(2015) Yusen Chen et al.   Journal of Stroke & Cerebrovascular Diseases

AKI Recovery Induced by Mesenchymal Stromal Cell-Derived Extracellular Vesicles Carrying MicroRNAs

(2015) F. Collino et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Diffusion-MRI in neurodegenerative disorders

(2015) Joseph Goveas et al.   MAGNETIC RESONANCE IMAGING

Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth

(2015) Lin Zhang et al.   NATURE

Spreading of pathology in neurodegenerative diseases: a focus on human studies

(2015) Johannes Brettschneider et al.   NATURE REVIEWS NEUROSCIENCE

Molecular mechanisms in the regulation of adult neurogenesis during stress

(2015) Martin Egeland et al.   NATURE REVIEWS NEUROSCIENCE

HucMSC-Exosome Mediated-Wnt4 Signaling Is Required for Cutaneous Wound Healing

(2015) Bin Zhang et al.   STEM CELLS

GDF-15 Secreted from Human Umbilical Cord Blood Mesenchymal Stem Cells Delivered Through the Cerebrospinal Fluid Promotes Hippocampal Neurogenesis and Synaptic Activity in an Alzheimer's Disease Model

(2015) Dong Hyun Kim et al.   STEM CELLS AND DEVELOPMENT

Exosomes: Novel Biomarkers for Clinical Diagnosis

(2015) Jin Lin et al.   TheScientificWorldJOURNAL

Ectosomes and exosomes: shedding the confusion between extracellular vesicles

(2015) Emanuele Cocucci et al.   TRENDS IN CELL BIOLOGY

Mesenchymal stem cells secretome as a modulator of the neurogenic niche: basic insights and therapeutic opportunities

(2015) Antonio J. Salgado et al.   Frontiers in Cellular Neuroscience

Neurogenesis following Stroke Affecting the Adult Brain

(2015) Olle Lindvall et al.   Cold Spring Harbor Perspectives in Biology

Adult Neurogenesis in Neurodegenerative Diseases: Figure 1.

(2015) Beate Winner et al.   Cold Spring Harbor Perspectives in Biology

Targeted exosome-mediated delivery of opioid receptor Mu siRNA for the treatment of morphine relapse

(2015) Yuchen Liu et al.   Scientific Reports

Serum Exosome MicroRNA as a Minimally-Invasive Early Biomarker of AML

(2015) Noah I. Hornick et al.   Scientific Reports

Gap junctional protein Cx43 is involved in the communication between extracellular vesicles and mammalian cells

(2015) Ana Rosa Soares et al.   Scientific Reports

Initial drug treatment in Parkinson’s disease:

(2015) Sharon Muzerengi et al.   BMJ-British Medical Journal

Extracellular Vesicles Improve Post-Stroke Neuroregeneration and Prevent Postischemic Immunosuppression

(2015) Thorsten R. Doeppner et al.   Stem Cells Translational Medicine

Initial drug treatment in Parkinson’s disease:

(2015) Sharon Muzerengi et al.   BMJ-British Medical Journal

The Role of Circulating Platelets Microparticles and Platelet Parameters in Acute Ischemic Stroke Patients

(2015) Yusen Chen et al.   Journal of Stroke & Cerebrovascular Diseases

Exosomes: Novel Biomarkers for Clinical Diagnosis

(2015) Jin Lin et al.   Scientific World Journal

Exosomes Secreted from CXCR4 Overexpressing Mesenchymal Stem Cells Promote Cardioprotection via Akt Signaling Pathway following Myocardial Infarction

(2015) Kai Kang et al.   Stem Cells International

Using Fluorescence Activated Cell Sorting to Examine Cell-Type-Specific Gene Expression in Rat Brain Tissue

(2015) Jaclyn M. Schwarz   Jove-Journal of Visualized Experiments

Assay Reproducibility in Clinical Studies of Plasma miRNA

(2015) Jonathan Rice et al.   PLoS One

Plasma Exosomal miRNAs in Persons with and without Alzheimer Disease: Altered Expression and Prospects for Biomarkers

(2015) Giovanni Lugli et al.   PLoS One

Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

(2014) Marina Colombo et al.   Annual Review of Cell and Developmental Biology

Hes1, a Notch signaling downstream target, regulates adult hippocampal neurogenesis following traumatic brain injury

(2014) Zhen Zhang et al.   BRAIN RESEARCH

Neurogenesis in the Striatum of the Adult Human Brain

(2014) Aurélie Ernst et al.   CELL

NFIX Regulates Proliferation and Migration Within the Murine SVZ Neurogenic Niche

(2014) Yee Hsieh Evelyn Heng et al.   CEREBRAL CORTEX

Biogenesis and secretion of exosomes

(2014) Joanna Kowal et al.   CURRENT OPINION IN CELL BIOLOGY

Exosome Uptake through Clathrin-mediated Endocytosis and Macropinocytosis and Mediating miR-21 Delivery

(2014) Tian Tian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteomics of extracellular vesicles: Exosomes and ectosomes

(2014) Dong-Sic Choi et al.   MASS SPECTROMETRY REVIEWS

Tenascins in stem cell niches

(2014) Ruth Chiquet-Ehrismann et al.   MATRIX BIOLOGY

Systemic exosomal siRNA delivery reduced alpha-synuclein aggregates in brains of transgenic mice

(2014) J. Mark Cooper et al.   MOVEMENT DISORDERS

Astroglial connexin 43 sustains glutamatergic synaptic efficacy

(2014) O. Chever et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Analysis of the RNA content of the exosomes derived from blood serum and urine and its potential as biomarkers

(2014) M. Li et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Multifaceted effects of oligodendroglial exosomes on neurons: impact on neuronal firing rate, signal transduction and gene regulation

(2014) D. Frohlich et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Sorting it out: Regulation of exosome loading

(2014) Carolina Villarroya-Beltri et al.   SEMINARS IN CANCER BIOLOGY

Mesenchymal Stem Cells Deliver Exogenous miRNAs to Neural Cells and Induce Their Differentiation and Glutamate Transporter Expression

(2014) Hae Kyung Lee et al.   STEM CELLS AND DEVELOPMENT

Exosomes/miRNAs as mediating cell-based therapy of stroke

(2014) Hongqi Xin et al.   Frontiers in Cellular Neuroscience

The Cell Biology of the Endocytic System from an Evolutionary Perspective

(2014) J. G. Wideman et al.   Cold Spring Harbor Perspectives in Biology

Mesenchymal stem cell-derived exosomes promote hepatic regeneration in drug-induced liver injury models

(2014) Cheau Tan et al.   Stem Cell Research & Therapy

Nontemplated Nucleotide Additions Distinguish the Small RNA Composition in Cells from Exosomes

(2014) Danijela Koppers-Lalic et al.   Cell Reports

Magnetic Resonance Spectroscopy: An In Vivo Molecular Imaging Biomarker for Parkinson’s Disease?

(2014) Rosella Ciurleo et al.   Biomed Research International

Adult Hippocampal Neurogenesis in Parkinson’s Disease: Impact on Neuronal Survival and Plasticity

(2014) Martin Regensburger et al.   NEURAL PLASTICITY

let-7 miRNAs Can Act through Notch to Regulate Human Gliogenesis

(2014) M. Patterson et al.   Stem Cell Reports

Systems Approach to Neurodegenerative Disease Biomarker Discovery

(2013) Christopher Lausted et al.   Annual Review of Pharmacology and Toxicology

Exosomes: mediators of communication in eukaryotes

(2013) María A Lopez-Verrilli et al.   BIOLOGICAL RESEARCH

Exosomes: the future of biomarkers in medicine

(2013) Francesca Properzi et al.   Biomarkers in Medicine

MiR-204 down regulates SIRT1 and reverts SIRT1-induced epithelial-mesenchymal transition, anoikis resistance and invasion in gastric cancer cells

(2013) Lihua Zhang et al.   BMC CANCER

Dynamics of Hippocampal Neurogenesis in Adult Humans

(2013) Kirsty L. Spalding et al.   CELL

Exosome Uptake Depends on ERK1/2-Heat Shock Protein 27 Signaling and Lipid Raft-mediated Endocytosis Negatively Regulated by Caveolin-1

(2013) Katrin J. Svensson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neutral Sphingomyelinase 2 (nSMase2)-dependent Exosomal Transfer of Angiogenic MicroRNAs Regulate Cancer Cell Metastasis

(2013) Nobuyoshi Kosaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Systemic Administration of Exosomes Released from Mesenchymal Stromal Cells Promote Functional Recovery and Neurovascular Plasticity After Stroke in Rats

(2013) Hongqi Xin et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Extracellular vesicles derived from human bone marrow mesenchymal stem cells promote angiogenesis in a rat myocardial infarction model

(2013) Suyan Bian et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Comprehensive Expression Analyses of Neural Cell-Type-Specific miRNAs Identify New Determinants of the Specification and Maintenance of Neuronal Phenotypes

(2013) A. Jovicic et al.   JOURNAL OF NEUROSCIENCE

Exosomes: Mediators of Neurodegeneration, Neuroprotection and Therapeutics

(2013) Anuradha Kalani et al.   MOLECULAR NEUROBIOLOGY

Expansion of oligodendrocyte progenitor cells following SIRT1 inactivation in the adult brain

(2013) Victoria A. Rafalski et al.   NATURE CELL BIOLOGY

MicroRNAs and other non-coding RNAs as targets for anticancer drug development

(2013) Hui Ling et al.   NATURE REVIEWS DRUG DISCOVERY

Extracellular vesicles: biology and emerging therapeutic opportunities

(2013) Samir EL Andaloussi et al.   NATURE REVIEWS DRUG DISCOVERY

Systemic treatment with adipose-derived mesenchymal stem cells ameliorates clinical and pathological features in the amyotrophic lateral sclerosis murine model

(2013) S. Marconi et al.   NEUROSCIENCE

Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity

(2013) H. C. Christianson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development

(2013) P. Kucharzewska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury

(2013) Fatih Arslan et al.   Stem Cell Research

MiR-133b Promotes Neural Plasticity and Functional Recovery After Treatment of Stroke with Multipotent Mesenchymal Stromal Cells in Rats Via Transfer of Exosome-Enriched Extracellular Particles

(2013) Hongqi Xin et al.   STEM CELLS

Neuronal dark matter: the emerging role of microRNAs in neurodegeneration

(2013) Emily F. Goodall et al.   Frontiers in Cellular Neuroscience

miR-9: a versatile regulator of neurogenesis

(2013) Marion Coolen et al.   Frontiers in Cellular Neuroscience

Choroid plexus transcytosis and exosome shuttling deliver folate into brain parenchyma

(2013) Marcel Grapp et al.   Nature Communications

Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs

(2013) Carolina Villarroya-Beltri et al.   Nature Communications

Neural Stem Cell Niches in Health and Diseases

(2012) Ilaria Decimo et al.   CURRENT PHARMACEUTICAL DESIGN

α-Synuclein Induces Alterations in Adult Neurogenesis in Parkinson Disease Models via p53-mediated Repression of Notch1

(2012) Paula Desplats et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamics of exosome internalization and trafficking

(2012) Tian Tian et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Promoting brain remodelling and plasticity for stroke recovery: therapeutic promise and potential pitfalls of clinical translation

(2012) Dirk M Hermann et al.   LANCET NEUROLOGY

Systemically Injected Exosomes Targeted to EGFR Deliver Antitumor MicroRNA to Breast Cancer Cells

(2012) Shin-ichiro Ohno et al.   MOLECULAR THERAPY

Get on the exosome bus with ALIX

(2012) James H. Hurley et al.   NATURE CELL BIOLOGY

Syndecan–syntenin–ALIX regulates the biogenesis of exosomes

(2012) Maria Francesca Baietti et al.   NATURE CELL BIOLOGY

MicroRNA profiling: approaches and considerations

(2012) Colin C. Pritchard et al.   NATURE REVIEWS GENETICS

The Molecular Profiles of Neural Stem Cell Niche in the Adult Subventricular Zone

(2012) Cheol Lee et al.   PLoS One

Depression and Hippocampal Neurogenesis: A Road to Remission?

(2012) A. J. Eisch et al.   SCIENCE

Exosome-Mediated Transfer of miR-133b from Multipotent Mesenchymal Stromal Cells to Neural Cells Contributes to Neurite Outgrowth

(2012) Hongqi Xin et al.   STEM CELLS

Transfer of Growth Factor Receptor mRNA Via Exosomes Unravels the Regenerative Effect of Mesenchymal Stem Cells

(2012) Susanna Tomasoni et al.   STEM CELLS AND DEVELOPMENT

Current Management of Juvenile Myelomonocytic Leukemia and the Impact of RAS Mutations

(2012) Nao Yoshida et al.   PEDIATRIC DRUGS

Assessment scales in dementia

(2012) Bart Sheehan   Therapeutic Advances in Neurological Disorders

Cell therapy for neonatal hypoxia-ischemia and cerebral palsy

(2011) Laura Bennet et al.   ANNALS OF NEUROLOGY

Multivesicular Body Morphogenesis

(2011) Phyllis I. Hanson et al.   Annual Review of Cell and Developmental Biology

Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes

(2011) A. Montecalvo et al.   BLOOD

Immunohistological markers for proliferative events, gliogenesis, and neurogenesis within the adult hippocampus

(2011) Oliver von Bohlen und Halbach   CELL AND TISSUE RESEARCH

Microautophagy of Cytosolic Proteins by Late Endosomes

(2011) Ranjit Sahu et al.   DEVELOPMENTAL CELL

Selective transfer of exosomes from oligodendrocytes to microglia by macropinocytosis

(2011) D. Fitzner et al.   JOURNAL OF CELL SCIENCE

Treatment of Brain Inflammatory Diseases by Delivering Exosome Encapsulated Anti-inflammatory Drugs From the Nasal Region to the Brain

(2011) Xiaoying Zhuang et al.   MOLECULAR THERAPY

Selection and characterization of tenascin C targeting peptide

(2011) Mee Young Kim et al.   MOLECULES AND CELLS

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

(2011) Lydia Alvarez-Erviti et al.   NATURE BIOTECHNOLOGY

A Quantitative Comparison of Cell-Type-Specific Microarray Gene Expression Profiling Methods in the Mouse Brain

(2011) Benjamin W. Okaty et al.   PLoS One

MicroRNA Profiling in Subventricular Zone after Stroke: MiR-124a Regulates Proliferation of Neural Progenitor Cells through Notch Signaling Pathway

(2011) Xian Shuang Liu et al.   PLoS One

Intranigral Transplantation of Epigenetically Induced BDNF-Secreting Human Mesenchymal Stem Cells: Implications for Cell-Based Therapies in Parkinson's Disease

(2010) Rodrigo Somoza et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

New Research Criteria for the Diagnosis of Alzheimer’s Disease Applied in a Memory Clinic Population

(2010) F.H. Bouwman et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Neurogenesis and epilepsy

(2010) Jack M. Parent et al.   EPILEPSIA

Exosome Secretion Ameliorates Lysosomal Storage of Cholesterol in Niemann-Pick Type C Disease

(2010) Katrin Strauss et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins

(2010) Caroline Subra et al.   JOURNAL OF LIPID RESEARCH

MicroRNAs Are Essential for the Developmental Switch from Neurogenesis to Gliogenesis in the Developing Spinal Cord

(2010) K. Zheng et al.   JOURNAL OF NEUROSCIENCE

Essential Roles of Notch Signaling in Maintenance of Neural Stem Cells in Developing and Adult Brains

(2010) I. Imayoshi et al.   JOURNAL OF NEUROSCIENCE

In Vivo Imaging of Amyloid Deposition in Alzheimer Disease Using the Radioligand 18F-AV-45 (Flobetapir F 18)

(2010) D. F. Wong et al.   JOURNAL OF NUCLEAR MEDICINE

Target-Specific PET Probes for Neurodegenerative Disorders Related to Dementia

(2010) A. Kadir et al.   JOURNAL OF NUCLEAR MEDICINE

Notch and EGFR pathway interaction regulates neural stem cell number and self-renewal

(2010) Adan Aguirre et al.   NATURE

The benefits and limitations of animal models for translational research in neurodegenerative diseases

(2010) Mathias Jucker   NATURE MEDICINE

New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?

(2010) Wei Deng et al.   NATURE REVIEWS NEUROSCIENCE

Functional delivery of viral miRNAs via exosomes

(2010) D. M. Pegtel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exosomes: immune properties and potential clinical implementations

(2010) Nathalie Chaput et al.   Seminars in Immunopathology

Cellular Internalization of Exosomes Occurs Through Phagocytosis

(2010) Du Feng et al.   TRAFFIC

Homing of stem cells to sites of inflammatory brain injury after intracerebral and intravenous administration: a longitudinal imaging study

(2010) Johanna S Jackson et al.   Stem Cell Research & Therapy

Advances in the treatment of neurodegenerative disorders employing nanotechnology

(2009) Girish Modi et al.   Annals of the New York Academy of Sciences

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

(2009) Raphael Kopan et al.   CELL

Exosomes – vesicular carriers for intercellular communication

(2009) Mikael Simons et al.   CURRENT OPINION IN CELL BIOLOGY

Microenvironmental pH Is a Key Factor for Exosome Traffic in Tumor Cells

(2009) Isabella Parolini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Four Decades of Neurodegenerative Disease Research: How Far We Have Come!

(2009) A. B. Young   JOURNAL OF NEUROSCIENCE

Mesenchymal stem cells increase hippocampal neurogenesis and counteract depressive-like behavior

(2009) M Tfilin et al.   MOLECULAR PSYCHIATRY

Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity

(2009) Derrick J. Gibbings et al.   NATURE CELL BIOLOGY

Fine control: microRNA regulation of adult neurogenesis

(2009) Qin Shen et al.   NATURE NEUROSCIENCE

Vascular niche factor PEDF modulates Notch-dependent stemness in the adult subependymal zone

(2009) Celia Andreu-Agulló et al.   NATURE NEUROSCIENCE

Simultaneous prospective purification of adult subventricular zone neural stem cells and their progeny

(2009) E. Pastrana et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Shedding microvesicles: artefacts no more

(2009) Emanuele Cocucci et al.   TRENDS IN CELL BIOLOGY

Regenerative effect of neural-induced human mesenchymal stromal cells in rat models of Parkinson's disease

(2008) Y.S. Levy et al.   CYTOTHERAPY

Trafficking and function of the tetraspanin CD63

(2008) Maaike S. Pols et al.   EXPERIMENTAL CELL RESEARCH

Proteomic and immunologic analyses of brain tumor exosomes

(2008) Michael W. Graner et al.   FASEB JOURNAL

Taking stem cells to the clinic: Major challenges

(2008) Ariff Bongso et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Noggin Expands Neural Stem Cells in the Adult Hippocampus

(2008) M. A. Bonaguidi et al.   JOURNAL OF NEUROSCIENCE

Structure of the guide-strand-containing argonaute silencing complex

(2008) Yanli Wang et al.   NATURE

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY

Dynamic Notch signaling in neural progenitor cells and a revised view of lateral inhibition

(2008) Ryoichiro Kageyama et al.   NATURE NEUROSCIENCE

Symptomatic treatment of Huntington disease

(2008) Octavian R. Adam et al.   Neurotherapeutics

Thoughts on limitations of animal models

(2008) Thomas Hartung   PARKINSONISM & RELATED DISORDERS

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

(2008) K. Trajkovic et al.   SCIENCE