Exosomes: the future of biomarkers in medicine

Real time quaking-induced conversion analysis of cerebrospinal fluid in sporadic Creutzfeldt-Jakob disease

(2012) Lynne I. McGuire et al.   ANNALS OF NEUROLOGY

γ-Synuclein: Seeding of α-Synuclein Aggregation and Transmission between Cells

(2012) Irina Surgucheva et al.   BIOCHEMISTRY

Exosomes: Current knowledge of their composition, biological functions, and diagnostic and therapeutic potentials

(2012) Alexander V. Vlassov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseases

(2012) Shashi Bala et al.   HEPATOLOGY

Exosomal cell-to-cell transmission of alpha synuclein oligomers

(2012) Karin M Danzer et al.   Molecular Neurodegeneration

Protein misfolding cyclic amplification of infectious prions

(2012) Rodrigo Morales et al.   Nature Protocols

Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells

(2012) Shayne A. Bellingham et al.   NUCLEIC ACIDS RESEARCH

A systematic approach to exosome-based translational nanomedicine

(2012) Joshua L. Hood et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Plasmacytoid Dendritic Cells Sequester High Prion Titres at Early Stages of Prion Infection

(2012) Rocio Castro-Seoane et al.   PLoS Pathogens

Endosome maturation

(2011) Jatta Huotari et al.   EMBO JOURNAL

Exosome-associated Tau Is Secreted in Tauopathy Models and Is Selectively Phosphorylated in Cerebrospinal Fluid in Early Alzheimer Disease

(2011) Sudad Saman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microvesicles and exosomes: Opportunities for cell-derived membrane vesicles in drug delivery

(2011) Susan M. van Dommelen et al.   JOURNAL OF CONTROLLED RELEASE

Exosomal transmission of functional aquaporin 2 in kidney cortical collecting duct cells

(2011) Jonathan M. Street et al.   JOURNAL OF PHYSIOLOGY-LONDON

Body fluid derived exosomes as a novel template for clinical diagnostics

(2011) Sascha Keller et al.   Journal of Translational Medicine

Detection of prion infection in variant Creutzfeldt-Jakob disease: a blood-based assay

(2011) Julie Ann Edgeworth et al.   LANCET

Identification of an inhibitory budding signal that blocks the release of HIV particles and exosome/microvesicle proteins

(2011) Xin Gan et al.   MOLECULAR BIOLOGY OF THE CELL

Treatment of Brain Inflammatory Diseases by Delivering Exosome Encapsulated Anti-inflammatory Drugs From the Nasal Region to the Brain

(2011) Xiaoying Zhuang et al.   MOLECULAR THERAPY

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

(2011) Lydia Alvarez-Erviti et al.   NATURE BIOTECHNOLOGY

Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission

(2011) Lydia Alvarez-Erviti et al.   NEUROBIOLOGY OF DISEASE

Exosome Secretion: Molecular Mechanisms and Roles in Immune Responses

(2011) Angélique Bobrie et al.   TRAFFIC

Transmission of circulating cell-free AA amyloid oligomers in exosomes vectors via a prion-like mechanism

(2010) Masayoshi Tasaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MicroRNAs as biomarkers for CNS cancer and other disorders

(2010) Enrico De Smaele et al.   BRAIN RESEARCH

Dendritic Cell-Derived Exosomes for Cancer Immunotherapy: What's Next?

(2010) S. Viaud et al.   CANCER RESEARCH

Hsp70 binds to PrPCin the process of PrPCrelease via exosomes from THP-1 monocytes

(2010) Gui‑hua Wang et al.   CELL BIOLOGY INTERNATIONAL

Exosomes and retroviruses: the chicken or the egg?

(2010) Nuria Izquierdo-Useros et al.   CELLULAR MICROBIOLOGY

Intracellular and Extracellular MicroRNAs in Breast Cancer

(2010) C. Corcoran et al.   CLINICAL CHEMISTRY

Secretory Mechanisms and Intercellular Transfer of MicroRNAs in Living Cells

(2010) Nobuyoshi Kosaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cell-Produced  -Synuclein Is Secreted in a Calcium-Dependent Manner by Exosomes and Impacts Neuronal Survival

(2010) E. Emmanouilidou et al.   JOURNAL OF NEUROSCIENCE

Exosomes: Extracellular organelles important in intercellular communication

(2010) Suresh Mathivanan et al.   Journal of Proteomics

Comparison of three methods for isolation of urinary microvesicles to identify biomarkers of nephrotic syndrome

(2010) Ilse M. Rood et al.   KIDNEY INTERNATIONAL

Nanostructural and Transcriptomic Analyses of Human Saliva Derived Exosomes

(2010) Viswanathan Palanisamy et al.   PLoS One

Functional delivery of viral miRNAs via exosomes

(2010) D. M. Pegtel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The propagation of prion-like protein inclusions in neurodegenerative diseases

(2010) Michel Goedert et al.   TRENDS IN NEUROSCIENCES

Membrane Vesicles Released by Intestinal Epithelial Cells Infected with Rotavirus Inhibit T-Cell Function

(2010) Alfonso Barreto et al.   VIRAL IMMUNOLOGY

Claudin-containing exosomes in the peripheral circulation of women with ovarian cancer

(2009) Jianghong Li et al.   BMC CANCER

Prostate cancer-derived urine exosomes: a novel approach to biomarkers for prostate cancer

(2009) J Nilsson et al.   BRITISH JOURNAL OF CANCER

Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes

(2009) Sascha Keller et al.   CANCER LETTERS

Exosomal MicroRNA: A Diagnostic Marker for Lung Cancer

(2009) Guilherme Rabinowits et al.   Clinical Lung Cancer

Exosomes: proteomic insights and diagnostic potential

(2009) Richard J Simpson et al.   Expert Review of Proteomics

Can urinary exosomes act as treatment response markers in prostate cancer?

(2009) Paul J Mitchell et al.   Journal of Translational Medicine

Proteomics Analysis of A33 Immunoaffinity-purified Exosomes Released from the Human Colon Tumor Cell Line LIM1215 Reveals a Tissue-specific Protein Signature

(2009) Suresh Mathivanan et al.   MOLECULAR & CELLULAR PROTEOMICS

Upregulation of miRNA hsa-miR-342-3p in experimental and idiopathic prion disease

(2009) Judith Montag et al.   Molecular Neurodegeneration

Exosomes from human saliva as a source of microRNA biomarkers

(2009) A Michael et al.   ORAL DISEASES

High Levels of Exosomes Expressing CD63 and Caveolin-1 in Plasma of Melanoma Patients

(2009) Mariantonia Logozzi et al.   PLoS One

Identification of extracellular δ-catenin accumulation for prostate cancer detection

(2009) Qun Lu et al.   PROSTATE

MicroRNA-206 Delays ALS Progression and Promotes Regeneration of Neuromuscular Synapses in Mice

(2009) A. H. Williams et al.   SCIENCE

Human platelets as a substrate source for the in vitro amplification of the abnormal prion protein (PrPSc) associated with variant Creutzfeldt-Jakob disease

(2009) Michael Jones et al.   TRANSFUSION

Proteomic profiling of human plasma exosomes identifies PPARγ as an exosome-associated protein

(2008) Christopher Looze et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mouse neuroblastoma cells release prion infectivity associated with exosomal vesicles

(2008) Sandrine Alais et al.   BIOLOGY OF THE CELL

Prion diseases are efficiently transmitted by blood transfusion in sheep

(2008) F. Houston et al.   BLOOD

Capture and transfer of HIV-1 particles by mature dendritic cells converges with the exosome-dissemination pathway

(2008) N. Izquierdo-Useros et al.   BLOOD

Exosomal sorting of the cytoplasmic domain of bovine leukemia virus TM Env protein

(2008) A DEGASSART et al.   CELL BIOLOGY INTERNATIONAL

MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer

(2008) Douglas D. Taylor et al.   GYNECOLOGIC ONCOLOGY

Localization and trafficking of aquaporin 2 in the kidney

(2008) Kuniaki Takata et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Isolation and Identification of Potential Urinary Microparticle Biomarkers of Bladder Cancer

(2008) David M. Smalley et al.   JOURNAL OF PROTEOME RESEARCH

Large-Scale Proteomics and Phosphoproteomics of Urinary Exosomes

(2008) P. A. Gonzales et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY

A miRNA Signature of Prion Induced Neurodegeneration

(2008) Reuben Saba et al.   PLoS One

Proteomic profiling of exosomes: Current perspectives

(2008) Richard J. Simpson et al.   PROTEOMICS

CD45 immunoaffinity depletion of vesicles from Jurkat T cells demonstrates that exosomes contain CD45: no evidence for a distinct exosome/HIV-1 budding pathway

(2008) Lori V Coren et al.   Retrovirology