Cyanidin-3-O-glucoside from blueberry anthocyanin extracts protects ARPE-19 cells against high glucose damage via REDD1/GSK3β pathway

Müller Glial Expression of REDD1 is Required for Retinal Neurodegeneration and Visual Dysfunction in Diabetic Mice

(2022) William P. Miller et al.   DIABETES

Current Knowledge on Intestinal Absorption of Anthocyanins

(2022) Tae Hun Hahm et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Circ_NNT suppresses the apoptosis and inflammation in glucose-induced human retinal pigment epithelium by regulating miR-320b/TIMP3 axis in diabetic retinopathy

(2022) Qian Liu et al.   CLINICAL IMMUNOLOGY

Berberine-mediated REDD1 down-regulation ameliorates senescence of retinal pigment epithelium by interrupting the ROS-DDR positive feedback loop

(2022) Qingqiu Chen et al.   PHYTOMEDICINE

Blueberry anthocyanins extract attenuated diabetic retinopathy by inhibiting endoplasmic reticulum stress via the miR-182/OGG1 axis

(2022) Chaoqun Wang et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Blueberry Anthocyanins from Commercial Products: Structure Identification and Potential for Diabetic Retinopathy Amelioration

(2022) Rui Li et al.   MOLECULES

Blocking REDD1/TXNIP Complex Ameliorates HG-Induced Renal Tubular Epithelial Cell Apoptosis and EMT through Repressing Oxidative Stress

(2022) Lin Mu et al.   International Journal of Endocrinology

The stress response protein REDD1 as a causal factor for oxidative stress in diabetic retinopathy

(2021) William P. Miller et al.   FREE RADICAL BIOLOGY AND MEDICINE

Attenuation of High Glucose-Induced Damage in RPE Cells through p38 MAPK Signaling Pathway Inhibition

(2021) Grazia Maugeri et al.   Frontiers in Pharmacology

Cyanidin-3-o-glucoside (C3G) inhibits vascular leakage regulated by microglial activation in early diabetic retinopathy and neovascularization in advanced diabetic retinopathy

(2021) Fangling Zhao et al.   Bioengineered

Hypoglycemic and hypolipidemic effects of blueberry anthocyanins by AMPK activation: In vitro and in vivo studies

(2021) Daniela D. Herrera-Balandrano et al.   Redox Biology

The stress response protein REDD1 promotes diabetes-induced oxidative stress in the retina by Keap1-independent Nrf2 degradation

(2020) William P. Miller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ginsenoside Re Treatment Attenuates Myocardial Hypoxia/Reoxygenation Injury by Inhibiting HIF-1α Ubiquitination

(2020) Huiyuan Sun et al.   Frontiers in Pharmacology

Interphotoreceptor Retinol-Binding Protein Ameliorates Diabetes-induced Retinal Dysfunction and Neurodegeneration through Rhodopsin

(2020) Jianglei Chen et al.   DIABETES

Photoreceptor cells and RPE contribute to the development of diabetic retinopathy

(2020) Deoye Tonade et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Recent Research on the Health Benefits of Blueberries and Their Anthocyanins

(2019) Wilhelmina Kalt et al.   Advances in Nutrition

Inhibiting microRNA-144 potentiates Nrf2-dependent antioxidant signaling in RPE and protects against oxidative stress-induced outer retinal degeneration

(2019) Ravirajsinh N. Jadeja et al.   Redox Biology

Visualization of the distribution of anthocyanin species in mice eyeball by matrix-assisted laser desorption/ionization mass spectrometry imaging

(2018) Shuhei Yamada et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Quercetin and cyanidin-3-glucoside protect against photooxidation and photodegradation of A2E in retinal pigment epithelial cells

(2017) Yong Wang et al.   EXPERIMENTAL EYE RESEARCH

The Anthocyanins, Oenin and Callistephin, Protect RPE Cells Against Oxidative Stress

(2017) Sally M. Yacout et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

The impact of oxidative stress and inflammation on RPE degeneration in non-neovascular AMD

(2017) Sayantan Datta et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Anthocyanins as promising molecules and dietary bioactive components against diabetes – A review of recent advances

(2017) Vemana Gowd et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Effects of diabetic retinopathy on the barrier functions of the retinal pigment epithelium

(2017) Tina Xia et al.   VISION RESEARCH

Implication of REDD1 in the activation of inflammatory pathways

(2017) Faustine Pastor et al.   Scientific Reports

High glucose induces mitochondrial dysfunction and apoptosis in human retinal pigment epithelium cells via promoting SOCS1 and Fas/FasL signaling

(2016) Min Chen et al.   CYTOKINE

Effects of blueberry anthocyanins on retinal oxidative stress and inflammation in diabetes through Nrf2/HO-1 signaling

(2016) Yu Song et al.   JOURNAL OF NEUROIMMUNOLOGY

Cyanidin-3-glucoside and its phenolic acid metabolites attenuate visible light-induced retinal degeneration in vivo via activation of Nrf2/HO-1 pathway and NF-κB suppression

(2016) Yong Wang et al.   MOLECULAR NUTRITION & FOOD RESEARCH

The novel triterpenoid RTA 408 protects human retinal pigment epithelial cells against H2O2-induced cell injury via NF-E2-related factor 2 (Nrf2) activation

(2016) Xiaobin Liu et al.   Redox Biology

Early retinal pigment epithelium dysfunction is concomitant with hyperglycemia in mouse models of type 1 and type 2 diabetes

(2015) Ivy S. Samuels et al.   JOURNAL OF NEUROPHYSIOLOGY

O-GlcNAc Modification of Transcription Factor Sp1 Mediates Hyperglycemia-Induced VEGF-A Upregulation in Retinal Cells

(2014) K. Donovan et al.   INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Regulated in Development and DNA Damage 1 Is Necessary for Hyperglycemia-induced Vascular Endothelial Growth Factor Expression in the Retina of Diabetic Rodents

(2014) Michael D. Dennis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional architecture of the retina: Development and disease

(2014) Mrinalini Hoon et al.   PROGRESS IN RETINAL AND EYE RESEARCH

REDD1 enhances protein phosphatase 2A-mediated dephosphorylation of Akt to repress mTORC1 signaling

(2014) M. D. Dennis et al.   Science Signaling

Human metabolism and elimination of the anthocyanin, cyanidin-3-glucoside: a 13C-tracer study

(2013) Charles Czank et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The Expanding Role of Vascular Endothelial Growth Factor Inhibitors in Ophthalmology

(2012) Michael W. Stewart   MAYO CLINIC PROCEEDINGS

Microglia/Macrophages Migrate through Retinal Epithelium Barrier by a Transcellular Route in Diabetic Retinopathy

(2011) Samy Omri et al.   AMERICAN JOURNAL OF PATHOLOGY

The Genomic, Biochemical, and Cellular Responses of the Retina in Inherited Photoreceptor Degenerations and Prospects for the Treatment of These Disorders

(2010) Alexa N. Bramall et al.   Annual Review of Neuroscience