Berberine-mediated REDD1 down-regulation ameliorates senescence of retinal pigment epithelium by interrupting the ROS-DDR positive feedback loop

The stress response protein REDD1 as a causal factor for oxidative stress in diabetic retinopathy

(2021) William P. Miller et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cytoprotective Potential of Fucoxanthin in Oxidative Stress-Induced Age-Related Macular Degeneration and Retinal Pigment Epithelial Cell Senescence In Vivo and In Vitro

(2021) Shiu-Jau Chen et al.   Marine Drugs

Redd1 knockdown prevents doxorubicin-induced cardiac senescence

(2021) Pianpian Huang et al.   Aging-US

Oxidative and Nitrosative Stress in Age-Related Macular Degeneration: A Review of Their Role in Different Stages of Disease

(2021) Caterina Toma et al.   Antioxidants

YAP prevents premature senescence of astrocytes and cognitive decline of Alzheimer's disease through regulating CDK6 signaling

(2021) Xingxing Xu et al.   AGING CELL

Nitazoxanide impairs mitophagy flux through ROS-mediated mitophagy initiation and lysosomal dysfunction in bladder cancer

(2021) Haiyan Sun et al.   BIOCHEMICAL PHARMACOLOGY

Targeting senescent retinal pigment epithelial cells facilitates retinal regeneration in mouse models of age-related macular degeneration

(2021) Jae-Byoung Chae et al.   GeroScience

REDD1 deficiency protects against nonalcoholic hepatic steatosis induced by high‐fat diet

(2020) Karine Dumas et al.   FASEB JOURNAL

The stress response protein REDD1 promotes diabetes-induced oxidative stress in the retina by Keap1-independent Nrf2 degradation

(2020) William P. Miller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of mitochondrial dysfunction and their impact on age-related macular degeneration

(2020) Kai Kaarniranta et al.   PROGRESS IN RETINAL AND EYE RESEARCH

TXNIP/Redd1 signalling and excessive autophagy: a novel mechanism of myocardial ischaemia/reperfusion injury in mice

(2019) Chao Gao et al.   CARDIOVASCULAR RESEARCH

Berberine ameliorates cellular senescence and extends the lifespan of mice via regulating p16 and cyclin protein expression

(2019) Yao Dang et al.   AGING CELL

The impact of oxidative stress and inflammation on RPE degeneration in non-neovascular AMD

(2017) Sayantan Datta et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Quantifying melanin concentration in retinal pigment epithelium using broadband photoacoustic microscopy

(2017) Xiao Shu et al.   Biomedical Optics Express

p53 in the DNA-Damage-Repair Process

(2016) Ashley B. Williams et al.   Cold Spring Harbor Perspectives in Medicine

A REDD1/TXNIP pro-oxidant complex regulates ATG4B activity to control stress-induced autophagy and sustain exercise capacity

(2015) Shuxi Qiao et al.   Nature Communications

Hypoxia inhibits senescence and maintains mesenchymal stem cell properties through down-regulation of E2A-p21 by HIF-TWIST

(2010) C.-C. Tsai et al.   BLOOD

Feedback between p21 and reactive oxygen production is necessary for cell senescence

(2010) João F Passos et al.   Molecular Systems Biology

Negative feedback control of HIF-1 through REDD1-regulated ROS suppresses tumorigenesis

(2010) P. Horak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA