Nitrosative Stress, Hypernitrosylation, and Autoimmune Responses to Nitrosylated Proteins: New Pathways in Neuroprogressive Disorders Including Depression and Chronic Fatigue Syndrome

So depression is an inflammatory disease, but where does the inflammation come from?

(2016) Michael Berk et al.   BMC Medicine

S-Nitrosylation in neurogenesis and neuronal development

(2015) Shu-ichi Okamoto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Central pathways causing fatigue in neuro-inflammatory and autoimmune illnesses

(2015) Gerwyn Morris et al.   BMC Medicine

The many roads to mitochondrial dysfunction in neuroimmune and neuropsychiatric disorders

(2015) Gerwyn Morris et al.   BMC Medicine

The CB1 cannabinoid receptor signals striatal neuroprotection via a PI3K/Akt/mTORC1/BDNF pathway

(2015) C Blázquez et al.   CELL DEATH AND DIFFERENTIATION

The Toll-Like Receptor Radical Cycle Pathway: A New Drug Target in Immune-Related Chronic Fatigue

(2015) Kurt Lucas et al.   CNS & Neurological Disorders-Drug Targets

A systematic review of the incidence and prevalence of comorbidity in multiple sclerosis: Overview

(2015) Ruth Ann Marrie et al.   Multiple Sclerosis Journal

Aberrant protein S-nitrosylation contributes to the pathophysiology of neurodegenerative diseases

(2015) Tomohiro Nakamura et al.   NEUROBIOLOGY OF DISEASE

Nitrosative Stress in the Nervous System: Guidelines for Designing Experimental Strategies to Study Protein S-Nitrosylation

(2015) Tomohiro Nakamura et al.   NEUROCHEMICAL RESEARCH

Omics-based depression and inflammation research

(2015) Michael Maes et al.   REVISTA BRASILEIRA DE PSIQUIATRIA

A systematic review of the incidence and prevalence of comorbidity in multiple sclerosis: Overview

(2015) Ruth Ann Marrie et al.   Multiple Sclerosis Journal

Dysbiosis in the Gut Microbiota of Patients with Multiple Sclerosis, with a Striking Depletion of Species Belonging to Clostridia XIVa and IV Clusters

(2015) Sachiko Miyake et al.   PLoS One

Proteomic Profiling of Nitrosative Stress: Protein S-Oxidation Accompanies S-Nitrosylation

(2014) Yue-Ting Wang et al.   ACS Chemical Biology

Mitochondrial respiratory chain complexes as sources and targets of thiol-based redox-regulation

(2014) Stefan Dröse et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Respiratory Substrates Regulate S-Nitrosylation of Mitochondrial Proteins through a Thiol-Dependent Pathway

(2014) Allen H. K. Chang et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Oxidative and Nitrosative Stress and Immune-inflammatory Pathways in Patients with Myalgic Encephalomyelitis (ME)/Chronic Fatigue Syndrome (CFS)

(2014) Gerwyn Morris et al.   Current Neuropharmacology

Differential inhibition of Arabidopsis superoxide dismutases by peroxynitrite-mediated tyrosine nitration

(2014) Christian Holzmeister et al.   JOURNAL OF EXPERIMENTAL BOTANY

The Glutathione System: A New Drug Target in Neuroimmune Disorders

(2014) Gerwyn Morris et al.   MOLECULAR NEUROBIOLOGY

Oxidative & nitrosative stress in depression: Why so much stress?

(2014) Steven Moylan et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

dbSNO 2.0: a resource for exploring structural environment, functional and disease association and regulatory network of protein S-nitrosylation

(2014) Yi-Ju Chen et al.   NUCLEIC ACIDS RESEARCH

Inflammatory stimuli induce inhibitory S-nitrosylation of the deacetylase SIRT1 to increase acetylation and activation of p53 and p65

(2014) S. Shinozaki et al.   Science Signaling

S-Nitrosylation-Mediated Redox Transcriptional Switch Modulates Neurogenesis and Neuronal Cell Death

(2014) Shu-ichi Okamoto et al.   Cell Reports

NF-κB Mediated Regulation of Adult Hippocampal Neurogenesis: Relevance to Mood Disorders and Antidepressant Activity

(2014) Valeria Bortolotto et al.   Biomed Research International

Protein disulfide isomerase a multifunctional protein with multiple physiological roles

(2014) Hyder Ali Khan et al.   Frontiers in Chemistry

Reduction of cardiomyocyte S-nitrosylation by S-nitrosoglutathione reductase protects against sepsis-induced myocardial depression

(2013) Patrick Y. Sips et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

May the Evaluation of Nitrosative Stress Through Selective Increase of 3-Nitrotyrosine Proteins Other Than Nitroalbumin and Dominant Tyrosine-125/136 Nitrosylation of Serum α-Synuclein Serve for Diagnosis of Sporadic Parkinson's Disease?

(2013) Emilio Fernández et al.   ANTIOXIDANTS & REDOX SIGNALING

The cholinergic anti-inflammatory pathway: A critical review

(2013) D. Martelli et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Myalgic encephalomyelitis/chronic fatigue syndrome and encephalomyelitis disseminata/multiple sclerosis show remarkable levels of similarity in phenomenology and neuroimmune characteristics

(2013) Gerwyn Morris et al.   BMC Medicine

A narrative review on the similarities and dissimilarities between myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and sickness behavior

(2013) Gerwyn Morris et al.   BMC Medicine

The IL-10/STAT3-mediated anti-inflammatory response: recent developments and future challenges

(2013) A. P. Hutchins et al.   Briefings in Functional Genomics

Role of Immune-Inflammatory and Oxidative and Nitrosative Stress Pathways in the Etiology of Depression: Therapeutic Implications

(2013) George Anderson et al.   CNS DRUGS

Tumor Suppression: p53 Alters Immune Surveillance to Restrain Liver Cancer

(2013) Nitin Raj et al.   CURRENT BIOLOGY

Autoimmune (Auto-inflammatory) Syndrome Induced by Adjuvants (ASIA) – Animal Models as a Proof of Concept

(2013) Paola Cruz-Tapias et al.   CURRENT MEDICINAL CHEMISTRY

Redox regulation of SIRT1 in inflammation and cellular senescence

(2013) Jae-woong Hwang et al.   FREE RADICAL BIOLOGY AND MEDICINE

The emerging role of the Nrf2-Keap1 signaling pathway in cancer

(2013) M. C. Jaramillo et al.   GENES & DEVELOPMENT

Regulation of Protein Function and Signaling by Reversible CysteineS-Nitrosylation

(2013) Neal Gould et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

S-nitrosylation: integrator of cardiovascular performance and oxygen delivery

(2013) Saptarsi M. Haldar et al.   JOURNAL OF CLINICAL INVESTIGATION

Short-term inhalation of nitric oxide inhibits activations of toll-like receptor 2 and 4 in the lung after ischemia-reperfusion injury in mice

(2013) Zhi-kun Zheng et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

Cleavage of GSK-3β by calpain counteracts the inhibitory effect of Ser9 phosphorylation on GSK-3β activity induced by H2O2

(2013) Ye Feng et al.   JOURNAL OF NEUROCHEMISTRY

IgM to S-nitrosylated protein is found intrathecally in relapsing–remitting multiple sclerosis

(2013) Charlotte Hvaring et al.   JOURNAL OF NEUROIMMUNOLOGY

The Ability of BDNF to Modify Neurogenesis and Depressive-Like Behaviors Is Dependent upon Phosphorylation of Tyrosine Residues 365/367 in the GABAA-Receptor  2 Subunit

(2013) M. Vithlani et al.   JOURNAL OF NEUROSCIENCE

Role of the Toll Like Receptor (TLR) Radical Cycle in Chronic Inflammation: Possible Treatments Targeting the TLR4 Pathway

(2013) Kurt Lucas et al.   MOLECULAR NEUROBIOLOGY

Modulation of oxidative stress as an anticancer strategy

(2013) Chiara Gorrini et al.   NATURE REVIEWS DRUG DISCOVERY

Aberrant Protein S-Nitrosylation in Neurodegenerative Diseases

(2013) Tomohiro Nakamura et al.   NEURON

The shared role of oxidative stress and inflammation in major depressive disorder and nicotine dependence

(2013) Sandra Odebrecht Vargas Nunes et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

S-nitrosylation of AMPA receptor GluA1 regulates phosphorylation, single-channel conductance, and endocytosis

(2013) B. Selvakumar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

S-nitrosylated SHP-2 contributes to NMDA receptor-mediated excitotoxicity in acute ischemic stroke

(2013) Z.-Q. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Staging and Neuroprogression in Bipolar Disorder: A Systematic Review of the Literature

(2013) Clarissa Severino Gama et al.   REVISTA BRASILEIRA DE PSIQUIATRIA

Nitric Oxide Regulates Mitochondrial Fatty Acid Metabolism Through Reversible Protein S-Nitrosylation

(2013) P.-T. Doulias et al.   Science Signaling

Activation of TLR4 signaling promotes gastric cancer progression by inducing mitochondrial ROS production

(2013) X Yuan et al.   Cell Death & Disease

Mitochondrial dysfunction, oxidative stress, and major depressive disorder

(2013) Edward Tobe   Neuropsychiatric Disease and Treatment

Nitric oxide-based protein modification: formation and site-specificity of protein S-nitrosylation

(2013) Izabella Kovacs et al.   Frontiers in Plant Science

Mitochondrial Permeability Transition and Cell Death: The Role of Cyclophilin D

(2013) Sabzali Javadov et al.   Frontiers in Physiology

B-1 Cell Immunoglobulin Directed Against Oxidation-Specific Epitopes

(2013) Dimitrios Tsiantoulas et al.   Frontiers in Immunology

Redox-derived damage-associated molecular patterns: Ligand function of lipid peroxidation adducts

(2013) Koji Uchida   Redox Biology

Redox regulation of mitochondrial function with emphasis on cysteine oxidation reactions

(2013) Ryan J. Mailloux et al.   Redox Biology

Protein Tyrosine Nitration: Biochemical Mechanisms and Structural Basis of Functional Effects

(2012) Rafael Radi   ACCOUNTS OF CHEMICAL RESEARCH

Small changes huge impact: the role of thioredoxin 1 in the regulation of apoptosis by S-nitrosylation

(2012) H. Li et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

In depression, bacterial translocation may drive inflammatory responses, oxidative and nitrosative stress (O&NS), and autoimmune responses directed against O&NS-damaged neoepitopes

(2012) M. Maes et al.   ACTA PSYCHIATRICA SCANDINAVICA

TLR2 ligand engagement upregulates airway smooth muscle TNFα-induced cytokine production

(2012) Melanie Manetsch et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Glutathione Efflux and Cell Death

(2012) Rodrigo Franco et al.   ANTIOXIDANTS & REDOX SIGNALING

Emerging Role of Protein-Protein Transnitrosylation in Cell Signaling Pathways

(2012) Tomohiro Nakamura et al.   ANTIOXIDANTS & REDOX SIGNALING

S-Nitrosylation: Specificity, Occupancy, and Interaction with Other Post-Translational Modifications

(2012) Alicia M. Evangelista et al.   ANTIOXIDANTS & REDOX SIGNALING

The innate immune response to products of phospholipid peroxidation

(2012) David Weismann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways

(2012) Michael Maes et al.   BMC Medicine

Dysregulated relationship of inflammation and oxidative stress in major depression

(2012) B.J. Rawdin et al.   BRAIN BEHAVIOR AND IMMUNITY

The HumanTLRInnate Immune Gene Family Is Differentially Influenced by DNA Stress andp53Status in Cancer Cells

(2012) Maria Shatz et al.   CANCER RESEARCH

Interactions between the tumor suppressor p53 and immune responses

(2012) Daniel Menendez et al.   CURRENT OPINION IN ONCOLOGY

The Role of Oxidative Stress in Depressive Disorders

(2012) Tanja Maria Michel et al.   CURRENT PHARMACEUTICAL DESIGN

Increased autoimmune responses against auto-epitopes modified by oxidative and nitrosative damage in depression: Implications for the pathways to chronic depression and neuroprogression

(2012) Michael Maes et al.   JOURNAL OF AFFECTIVE DISORDERS

Inhibition of Glycogen Synthase Kinase-3 Ameliorates β-Amyloid Pathology and Restores Lysosomal Acidification and Mammalian Target of Rapamycin Activity in the Alzheimer Disease Mouse Model

(2012) Limor Avrahami et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antigen-Driven Induction of Polyreactive IgM during Intracellular Bacterial Infection

(2012) D. D. Jones et al.   JOURNAL OF IMMUNOLOGY

Enzymatic mechanisms regulating protein S-nitrosylation: implications in health and disease

(2012) Puneet Anand et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Increased nuclear factor-κB and loss of p53 are key mechanisms in Myalgic Encephalomyelitis/chronic fatigue syndrome (ME/CFS)

(2012) Gerwyn Morris et al.   MEDICAL HYPOTHESES

A neuro-immune model of Myalgic Encephalomyelitis/Chronic fatigue syndrome

(2012) Gerwyn Morris et al.   METABOLIC BRAIN DISEASE

The neuroprogressive nature of major depressive disorder: pathways to disease evolution and resistance and therapeutic implications

(2012) S Moylan et al.   MOLECULAR PSYCHIATRY

Exogenous nitric oxide negatively regulates the S-nitrosylation p38 mitogen-activated protein kinase activation during cerebral ischaemia and reperfusion

(2012) S. H. Qi et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Xanthine oxidase-mediated denitrosation of N-nitroso-tryptophan by superoxide and uric acid

(2012) Kimberley Viles et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Increased ventricular lactate in chronic fatigue syndrome. III. Relationships to cortical glutathione and clinical symptoms implicate oxidative stress in disorder pathophysiology

(2012) Dikoma C. Shungu et al.   NMR IN BIOMEDICINE

Dynamic denitrosylation via S-nitrosoglutathione reductase regulates cardiovascular function

(2012) F. Beigi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased oxidative stress in patients with depression and its relationship to treatment

(2012) Cecilia P. Chung et al.   PSYCHIATRY RESEARCH

The Vagus Nerve and the Inflammatory Reflex: Wandering on a New Treatment Paradigm for Systemic Inflammation and Sepsis

(2012) Jared M. Huston   Surgical Infections

Chemotherapeutic induction of mitochondrial oxidative stress activates GSK-3α/β and Bax, leading to permeability transition pore opening and tumor cell death

(2012) F Chiara et al.   Cell Death & Disease

Thioredoxin 1-Mediated Post-Translational Modifications: Reduction, Transnitrosylation, Denitrosylation, and Related Proteomics Methodologies

(2011) Changgong Wu et al.   ANTIOXIDANTS & REDOX SIGNALING

S-Nitrosylation signaling regulates cellular protein interactions

(2011) Nadzeya V. Marozkina et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Regulation of mitochondrial processes by protein S-nitrosylation

(2011) Claude A. Piantadosi   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Redox modulation by S-nitrosylation contributes to protein misfolding, mitochondrial dynamics and neuronal synaptic damage in neurodegenerative diseases

(2011) T Nakamura et al.   CELL DEATH AND DIFFERENTIATION

Nitric oxide signaling: Classical, less classical, and nonclassical mechanisms

(2011) Antonio Martínez-Ruiz et al.   FREE RADICAL BIOLOGY AND MEDICINE

IgM-mediated autoimmune responses directed against multiple neoepitopes in depression: New pathways that underpin the inflammatory and neuroprogressive pathophysiology

(2011) Michael Maes et al.   JOURNAL OF AFFECTIVE DISORDERS

Regulation byS-Nitrosylation of Protein Post-translational Modification

(2011) Douglas T. Hess et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chemokine nitration prevents intratumoral infiltration of antigen-specific T cells

(2011) Barbara Molon et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Reactive Carbonyls Are a Major Th2-Inducing Damage-Associated Molecular Pattern Generated by Oxidative Stress

(2011) A. E. Moghaddam et al.   JOURNAL OF IMMUNOLOGY

The psychiatric manifestations of mitochondrial cytopathies: A clinical and MR spectroscopy investigation

(2011) Rebecca Anglin⁎ et al.   MITOCHONDRION

Identification and Quantification of S-Nitrosylation by Cysteine Reactive Tandem Mass Tag Switch Assay

(2011) Christopher I. Murray et al.   MOLECULAR & CELLULAR PROTEOMICS

Oxidation of the cysteine-rich regions of parkin perturbs its E3 ligase activity and contributes to protein aggregation

(2011) Fanjun Meng et al.   Molecular Neurodegeneration

S-Nitrosylation and S-Palmitoylation Reciprocally Regulate Synaptic Targeting of PSD-95

(2011) Gary P.H. Ho et al.   NEURON

Mechanistic explanations how cell-mediated immune activation, inflammation and oxidative and nitrosative stress pathways and their sequels and concomitants play a role in the pathophysiology of unipolar depression

(2011) Brian Leonard et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Nitric oxide activates Nrf2 through S-nitrosylation of Keap1 in PC12 cells

(2011) Han-Cheon Um et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

SNO-ing at the Nociceptive Synapse?

(2011) I. Tegeder et al.   PHARMACOLOGICAL REVIEWS

S-Nitrosylation activates Cdk5 and contributes to synaptic spine loss induced by  -amyloid peptide

(2011) J. Qu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation by glycogen synthase kinase-3 of inflammation and T cells in CNS diseases

(2011) Eléonore Beurel   Frontiers in Molecular Neuroscience

Nitric Oxide Signaling and Nitrosative Stress in Neurons: Role for S-Nitrosylation

(2010) Neelam Shahani et al.   ANTIOXIDANTS & REDOX SIGNALING

S-Nitrosylation of Critical Protein Thiols Mediates Protein Misfolding and Mitochondrial Dysfunction in Neurodegenerative Diseases

(2010) Tomohiro Nakamura et al.   ANTIOXIDANTS & REDOX SIGNALING

Thioredoxin and thioredoxin reductase: Current research with special reference to human disease

(2010) Arne Holmgren et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

IgA-mediated human autoimmune hemolytic anemia as a result of hemagglutination in the spleen, but independent of complement activation and Fc RI

(2010) P. Chadebech et al.   BLOOD

Blockade of self-reactive IgM significantly reduces injury in a murine model of acute myocardial infarction

(2010) M. S. Haas et al.   CARDIOVASCULAR RESEARCH

Protein S -Nitrosylation and Cardioprotection

(2010) Junhui Sun et al.   CIRCULATION RESEARCH

S -Nitrosylation in Cardiovascular Signaling

(2010) Brian Lima et al.   CIRCULATION RESEARCH

The SNO-proteome: causation and classifications

(2010) Divya Seth et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Toll-like Receptor 4 Mediates LPS-Induced Release of Nitric Oxide and Tumor Necrosis Factor-α by Embryonal Cardiomyocytes: Biological Significance and Clinical Implications in Human Pathology

(2010) M. Panaro et al.   CURRENT PHARMACEUTICAL DESIGN

Glycogen synthase kinase 3: A point of convergence for the host inflammatory response

(2010) Huizhi Wang et al.   CYTOKINE

Understanding the molecular mechanisms of the multifaceted IL-10-mediated anti-inflammatory response: Lessons from neutrophils

(2010) Flavia Bazzoni et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mitochondrial protein tyrosine nitration

(2010) Laura Castro et al.   FREE RADICAL RESEARCH

Fluctuation of serum vitamin E (α-tocopherol) concentrations during exacerbation and remission phases in patients with chronic fatigue syndrome

(2010) Kunihisa Miwa et al.   HEART AND VESSELS

Glycogen synthase kinase 3-β: A master regulator of toll-like receptor-mediated chronic intestinal inflammation

(2010) Claudia Hofmann et al.   INFLAMMATORY BOWEL DISEASES

Activation of NRF2 by Nitrosative Agents and H2O2Involves KEAP1 Disulfide Formation

(2010) Simon Fourquet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Natural IgM Antibodies Against Oxidation-Specific Epitopes

(2010) Christoph J. Binder   JOURNAL OF CLINICAL IMMUNOLOGY

Between nitros(yl)ation and nitration: Regulation of thioredoxin-1 in myocardial ischemia/reperfusion injury

(2010) Tienush Rassaf et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Nitrative inactivation of thioredoxin-1 increases vulnerability of diabetic hearts to ischemia/reperfusion injury

(2010) Tao Yin et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Protein tyrosine nitration in cellular signal transduction pathways

(2010) Vasily A. Yakovlev et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Redox Regulatory Mechanism of Transnitrosylation by Thioredoxin

(2010) Changgong Wu et al.   MOLECULAR & CELLULAR PROTEOMICS

Redox Reactions Induced by Nitrosative Stress Mediate Protein Misfolding and Mitochondrial Dysfunction in Neurodegenerative Diseases

(2010) Zezong Gu et al.   MOLECULAR NEUROBIOLOGY

Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders

(2010) Giles E. Hardingham et al.   NATURE REVIEWS NEUROSCIENCE

Association between depression severity and neurocognitive function in major depressive disorder: A review and synthesis.

(2010) Shawn M. McClintock et al.   NEUROPSYCHOLOGY

Pathways underlying neuroprogression in bipolar disorder: Focus on inflammation, oxidative stress and neurotrophic factors

(2010) M. Berk et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Redox-Sensitivity and Site-Specificity of S- and N- Denitrosation in Proteins

(2010) Frances L. Jourd'heuil et al.   PLoS One

An intriguing and hitherto unexplained co-occurrence: Depression and chronic fatigue syndrome are manifestations of shared inflammatory, oxidative and nitrosative (IO&NS) pathways

(2010) Michael Maes   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Depression and oxidative damage to lipids

(2010) Sarah Yager et al.   PSYCHONEUROENDOCRINOLOGY

S-Nitrosylation from GSNOR Deficiency Impairs DNA Repair and Promotes Hepatocarcinogenesis

(2010) W. Wei et al.   Science Translational Medicine

Protein disulphide isomerase protects against protein aggregation and is S-nitrosylated in amyotrophic lateral sclerosis

(2009) Adam K. Walker et al.   BRAIN

Glycogen synthase kinase-3 negatively regulates anti-inflammatory interleukin-10 for lipopolysaccharide-induced iNOS/NO biosynthesis and RANTES production in microglial cells

(2009) Wei-Ching Huang et al.   IMMUNOLOGY

The inhibition of JNK and p38 MAPKs downregulates IL-10 and differentially affects c-Jun gene expression in human monocytes

(2009) Zlatka Georgieva Dobreva et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Thioredoxin-interacting Protein (Txnip) Is a Feedback Regulator ofS-Nitrosylation

(2009) Michael T. Forrester et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Redox- and Calmodulin-dependentS-Nitrosylation of the KCNQ1 Channel

(2009) Ken Asada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Nrf2-Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress

(2009) Truyen Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In vivo cardioprotection by S-nitroso-2-mercaptopropionyl glycine

(2009) Sergiy M. Nadtochiy et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Involvement of S-Nitrosylation of Actin in Inhibition of Neurotransmitter Release by Nitric Oxide

(2009) Jingshan Lu et al.   Molecular Pain

A protective role of nuclear factor-erythroid 2-related factor-2 (Nrf2) in inflammatory disorders

(2009) Jiyoung Kim et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Protein denitrosylation: enzymatic mechanisms and cellular functions

(2009) Moran Benhar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

S-nitrosylation of stargazin regulates surface expression of AMPA-glutamate neurotransmitter receptors

(2009) B. Selvakumar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A mitochondria-targeted S-nitrosothiol modulates respiration, nitrosates thiols, and protects against ischemia-reperfusion injury

(2009) T. A. Prime et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate and adaptive immune responses regulated by glycogen synthase kinase-3 (GSK3)

(2009) Eléonore Beurel et al.   TRENDS IN IMMUNOLOGY

Protein S-nitrosylation in health and disease: a current perspective

(2009) Matthew W. Foster et al.   TRENDS IN MOLECULAR MEDICINE

S-nitrosylation of syntaxin 1 at Cys145is a regulatory switch controlling Munc18-1 binding

(2008) Zoë J. Palmer et al.   BIOCHEMICAL JOURNAL

Activation of Nrf2-antioxidant signaling attenuates NFκB-inflammatory response and elicits apoptosis

(2008) Wenge Li et al.   BIOCHEMICAL PHARMACOLOGY

The role of GSH efflux in staurosporine-induced apoptosis in colonic epithelial cells

(2008) Magdalena L. Circu et al.   BIOCHEMICAL PHARMACOLOGY

SIRT1 longevity factor suppresses NF-κB -driven immune responses: regulation of aging via NF-κB acetylation?

(2008) Antero Salminen et al.   BIOESSAYS

Nitrosothiol Reactivity Profiling Identifies S-Nitrosylated Proteins with Unexpected Stability

(2008) Jeremy S. Paige et al.   CHEMISTRY & BIOLOGY

The Compensatory Anti-inflammatory Response Syndrome (CARS) in Critically Ill Patients

(2008) Nicholas S. Ward et al.   CLINICS IN CHEST MEDICINE

Inflammatory and oxidative and nitrosative stress pathways underpinning chronic fatigue, somatization and psychosomatic symptoms

(2008) Michael Maes   CURRENT OPINION IN PSYCHIATRY

Elevated Toll-Like Receptor 4 Expression and Signaling in Muscle From Insulin-Resistant Subjects

(2008) S. M. Reyna et al.   DIABETES

Redox-based regulation of signal transduction: Principles, pitfalls, and promises

(2008) Yvonne M.W. Janssen-Heininger et al.   FREE RADICAL BIOLOGY AND MEDICINE

Regulation of the Catalytic Activity and Structure of Human Thioredoxin 1 via Oxidation andS-Nitrosylation of Cysteine Residues

(2008) Seyed Isaac Hashemy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plasma membrane glutathione transporters and their roles in cell physiology and pathophysiology

(2008) Nazzareno Ballatori et al.   MOLECULAR ASPECTS OF MEDICINE

Neurogenesis directed by Sirt1

(2008) Sergiy Libert et al.   NATURE CELL BIOLOGY

Proteomic analysis of protein S-nitrosylation

(2008) Federico Torta et al.   PROTEOMICS

Regulated Protein Denitrosylation by Cytosolic and Mitochondrial Thioredoxins

(2008) M. Benhar et al.   SCIENCE