Chemotherapeutic induction of mitochondrial oxidative stress activates GSK-3α/β and Bax, leading to permeability transition pore opening and tumor cell death
Published 2012 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Chemotherapeutic induction of mitochondrial oxidative stress activates GSK-3α/β and Bax, leading to permeability transition pore opening and tumor cell death
Authors
Keywords
-
Journal
Cell Death & Disease
Volume 3, Issue 12, Pages e444-e444
Publisher
Springer Nature
Online
2012-12-13
DOI
10.1038/cddis.2012.184
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Induction of the permeability transition pore in cells depleted of mitochondrial DNA
- (2012) Ionica Masgras et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- GSK-3β at the crossroads in the signalling of heart preconditioning: implication of mTOR and Wnt pathways
- (2011) François Vigneron et al. CARDIOVASCULAR RESEARCH
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Mitochondrial permeability transition in Ca2+-dependent apoptosis and necrosis
- (2011) Andrea Rasola et al. CELL CALCIUM
- Intracellular zinc release-activated ERK-dependent GSK-3β–p53 and Noxa–Mcl-1 signaling are both involved in cardiac ischemic-reperfusion injury
- (2011) C-L Lin et al. CELL DEATH AND DIFFERENTIATION
- SCaMC-1 promotes cancer cell survival by desensitizing mitochondrial permeability transition via ATP/ADP-mediated matrix Ca2+ buffering
- (2011) J Traba et al. CELL DEATH AND DIFFERENTIATION
- Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
- (2011) Gina M. DeNicola et al. NATURE
- Selective killing of K-ras mutant cancer cells by small molecule inducers of oxidative stress
- (2011) A. T. Shaw et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses
- (2011) D. Anastasiou et al. SCIENCE
- BAX unleashed: the biochemical transformation of an inactive cytosolic monomer into a toxic mitochondrial pore
- (2011) Loren D. Walensky et al. TRENDS IN BIOCHEMICAL SCIENCES
- GSK-3: Functional Insights from Cell Biology and Animal Models
- (2011) Oksana Kaidanovich-Beilin et al. Frontiers in Molecular Neuroscience
- Redox metabolism and malignancy
- (2010) Christina L Grek et al. CURRENT OPINION IN PHARMACOLOGY
- Signal transduction to the permeability transition pore
- (2010) Andrea Rasola et al. FEBS LETTERS
- Gold(III)-dithiocarbamato anticancer agents: Activity, toxicology and histopathological studies in rodents
- (2010) Cristina Marzano et al. INTERNATIONAL JOURNAL OF CANCER
- Antitumor activity of gold(III)-dithiocarbamato derivatives on prostate cancer cells and xenografts
- (2010) Lara Cattaruzza et al. INTERNATIONAL JOURNAL OF CANCER
- The architecture of respiratory complex I
- (2010) Rouslan G. Efremov et al. NATURE
- Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity
- (2010) F. Weinberg et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Control of the Metabolic Switch in Cancers by Oncogenes and Tumor Suppressor Genes
- (2010) A. J. Levine et al. SCIENCE
- Mitochondrial calcium and the permeability transition in cell death
- (2009) John J. Lemasters et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Mitochondrial Complex I decrease is responsible for bioenergetic dysfunction in K-ras transformed cells
- (2009) Alessandra Baracca et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Mitochondrial Respiratory Complex I: Structure, Function and Implication in Human Diseases
- (2009) Lokendra Sharma et al. CURRENT MEDICINAL CHEMISTRY
- The Midas touch in cancer chemotherapy: from platinum- to gold-dithiocarbamato complexes
- (2009) Luca Ronconi et al. DALTON TRANSACTIONS
- Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
- (2009) Dunyaporn Trachootham et al. NATURE REVIEWS DRUG DISCOVERY
- Activation of mitochondrial ERK protects cancer cells from death through inhibition of the permeability transition
- (2009) A. Rasola et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cadmium Toxicity toward Autophagy through ROS-Activated GSK-3β in Mesangial Cells
- (2009) Sheng-Hao Wang et al. TOXICOLOGICAL SCIENCES
- How mitochondria produce reactive oxygen species
- (2008) Michael P. Murphy BIOCHEMICAL JOURNAL
- Cancer Cell Metabolism: Warburg and Beyond
- (2008) Peggy P. Hsu et al. CELL
- Bcl-2 family proteins and cancer
- (2008) K W Yip et al. ONCOGENE
- Hexokinase II Detachment from Mitochondria Triggers Apoptosis through the Permeability Transition Pore Independent of Voltage-Dependent Anion Channels
- (2008) Federica Chiara et al. PLoS One
- Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes
- (2008) I. Szabo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mitochondria in cancer: Not just innocent bystanders
- (2008) Christian Frezza et al. SEMINARS IN CANCER BIOLOGY
- Mitochondria and cellular oxygen sensing in the HIF pathway
- (2007) Cormac T. Taylor BIOCHEMICAL JOURNAL
- The BCL-2 protein family: opposing activities that mediate cell death
- (2007) Richard J. Youle et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started