The neuroprogressive nature of major depressive disorder: pathways to disease evolution and resistance and therapeutic implications
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Title
The neuroprogressive nature of major depressive disorder: pathways to disease evolution and resistance and therapeutic implications
Authors
Keywords
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Journal
MOLECULAR PSYCHIATRY
Volume 18, Issue 5, Pages 595-606
Publisher
Springer Nature
Online
2012-04-24
DOI
10.1038/mp.2012.33
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Note: Only part of the references are listed.- Activity of mitochondrial respiratory chain is increased by chronic administration of antidepressants.
- (2011) Giselli Scaini et al. ACTA NEUROPSYCHIATRICA
- Interaction ofFKBP5Gene Variants and Adverse Life Events in Predicting Depression Onset: Results From a 10-Year Prospective Community Study
- (2011) Petra Zimmermann et al. AMERICAN JOURNAL OF PSYCHIATRY
- Proinflammatory activity and the sensitization of depressive-like behavior during maternal separation.
- (2011) Michael B. Hennessy et al. BEHAVIORAL NEUROSCIENCE
- The Emerging Role of Melatonin Agonists in the Treatment of Major Depression: Focus on Agomelatine
- (2011) Domenico De Berardis et al. CNS & Neurological Disorders-Drug Targets
- Steroid up-regulation of FKBP51 and its role in hormone signaling
- (2011) Tiina Jääskeläinen et al. CURRENT OPINION IN PHARMACOLOGY
- Nitric oxide modulation in protective role of antidepressants against chronic fatigue syndrome in mice
- (2011) Anil Kumar et al. INDIAN JOURNAL OF PHARMACOLOGY
- Glucocorticoid receptor polymorphism is associated with major depression and predominance of depression in the course of bipolar disorder
- (2011) Aleksandra Szczepankiewicz et al. JOURNAL OF AFFECTIVE DISORDERS
- IgM-mediated autoimmune responses directed against multiple neoepitopes in depression: New pathways that underpin the inflammatory and neuroprogressive pathophysiology
- (2011) Michael Maes et al. JOURNAL OF AFFECTIVE DISORDERS
- Increased autoimmune activity against 5-HT: A key component of depression that is associated with inflammation and activation of cell-mediated immunity, and with severity and staging of depression
- (2011) Michael Maes et al. JOURNAL OF AFFECTIVE DISORDERS
- Identification of a low–molecular weight TrkB antagonist with anxiolytic and antidepressant activity in mice
- (2011) Maxime Cazorla et al. JOURNAL OF CLINICAL INVESTIGATION
- The Effects of Fluoxetine Treatment in a Chronic Mild Stress Rat Model on Depression-Related Behavior, Brain Neurotrophins and ERK Expression
- (2011) Maya First et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Inflammation, mitochondria, and the inhibition of adult neurogenesis
- (2011) Ludmila A. Voloboueva et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Antidepressants increase human hippocampal neurogenesis by activating the glucocorticoid receptor
- (2011) C Anacker et al. MOLECULAR PSYCHIATRY
- Neuronal activity modifies the DNA methylation landscape in the adult brain
- (2011) Junjie U Guo et al. NATURE NEUROSCIENCE
- Depression, Antidepressants and Neurogenesis: A Critical Reappraisal
- (2011) Nicola D Hanson et al. NEUROPSYCHOPHARMACOLOGY
- Mechanistic explanations how cell-mediated immune activation, inflammation and oxidative and nitrosative stress pathways and their sequels and concomitants play a role in the pathophysiology of unipolar depression
- (2011) Brian Leonard et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Acetylsalicylic acid as an augmentation agent in fluoxetine treatment resistant depressive rats
- (2011) Ying Wang et al. NEUROSCIENCE LETTERS
- Nitric oxide and major depression
- (2011) Ashish Dhir et al. NITRIC OXIDE-BIOLOGY AND CHEMISTRY
- Antidepressant Drugs Transactivate TrkB Neurotrophin Receptors in the Adult Rodent Brain Independently of BDNF and Monoamine Transporter Blockade
- (2011) Tomi Rantamäki et al. PLoS One
- Activation of cell-mediated immunity in depression: Association with inflammation, melancholia, clinical staging and the fatigue and somatic symptom cluster of depression
- (2011) Michael Maes et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Erythropoietin: a candidate treatment for mood symptoms and memory dysfunction in depression
- (2011) Kamilla W. Miskowiak et al. PSYCHOPHARMACOLOGY
- Fluoxetine regulates the expression of neurotrophic/growth factors and glucose metabolism in astrocytes
- (2011) Igor Allaman et al. PSYCHOPHARMACOLOGY
- Toward an Anti-Inflammatory Strategy for Depression
- (2011) Shawn Hayley Frontiers in Behavioral Neuroscience
- Consumption of a palatable diet by chronically stressed rats prevents effects on anxiety-like behavior but increases oxidative stress in a sex-specific manner
- (2010) R. Krolow et al. APPETITE
- The role of BDNF in depression on the basis of its location in the neural circuitry
- (2010) Hui Yu et al. ACTA PHARMACOLOGICA SINICA
- Updated systematic review and meta-analysis of the effects of n−3 long-chain polyunsaturated fatty acids on depressed mood
- (2010) Katherine M Appleton et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Association of Western and Traditional Diets With Depression and Anxiety in Women
- (2010) Felice N. Jacka et al. AMERICAN JOURNAL OF PSYCHIATRY
- Chronic ω-3 fatty acids supplementation promotes beneficial effects on anxiety, cognitive and depressive-like behaviors in rats subjected to a restraint stress protocol
- (2010) Anete Curte Ferraz et al. BEHAVIOURAL BRAIN RESEARCH
- Noradrenaline acting at central β-adrenoceptors induces interleukin-10 and suppressor of cytokine signaling-3 expression in rat brain: Implications for neurodegeneration
- (2010) Eoin N. McNamee et al. BRAIN BEHAVIOR AND IMMUNITY
- Correlation of serum BDNF levels with hippocampal volumes in first episode, medication-free depressed patients
- (2010) Cagdas Eker et al. EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
- Epigenetic marking of the BDNF gene by early-life adverse experiences
- (2010) Tania L. Roth et al. HORMONES AND BEHAVIOR
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- (2010) Lesley Stafford et al. JOURNAL OF CLINICAL PSYCHIATRY
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- (2010) Robert K. McNamara JOURNAL OF NUTRITION
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- (2010) M L Molendijk et al. MOLECULAR PSYCHIATRY
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- (2010) Julie A. Pasco et al. PSYCHOTHERAPY AND PSYCHOSOMATICS
- Volumetric MRI studies of the hippocampus in major depressive disorder: Meanings of inconsistency and directions for future research
- (2010) Cagdas Eker et al. WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY
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- (2010) Luisella Bocchio-Chiavetto et al. WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY
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- (2009) Hao-ran Qian et al. ACTA PHARMACOLOGICA SINICA
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- (2009) Yekta Dowlati et al. BIOLOGICAL PSYCHIATRY
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- (2009) O. Dean et al. CURRENT MEDICINAL CHEMISTRY
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- (2009) Valentina Lorenzetti et al. JOURNAL OF AFFECTIVE DISORDERS
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- (2009) Kelly L. Weaver et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2009) Elisabeth B. Binder PSYCHONEUROENDOCRINOLOGY
- Associations of Depression With C-Reactive Protein, IL-1, and IL-6: A Meta-Analysis
- (2009) M Bryant Howren et al. PSYCHOSOMATIC MEDICINE
- Toxic Effects of Depression on Brain Function: Impairment of Delayed Recall and the Cumulative Length of Depressive Disorder in a Large Sample of Depressed Outpatients
- (2008) Philip Gorwood et al. AMERICAN JOURNAL OF PSYCHIATRY
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- (2008) Frederico F. Ferreira et al. BEHAVIOURAL PHARMACOLOGY
- S100B's double life: Intracellular regulator and extracellular signal
- (2008) Rosario Donato et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
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- (2008) Michael Berk et al. BIOLOGICAL PSYCHIATRY
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- (2008) Chi-Un Pae et al. BIOMEDICINE & PHARMACOTHERAPY
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- (2008) Cortney A. Turner et al. BRAIN RESEARCH
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- (2008) Lars Vedel Kessing BRITISH JOURNAL OF PSYCHIATRY
- Molecular Mechanisms and Pathophysiology of Necrotic Cell Death
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- (2008) J. Greilberger et al. FREE RADICAL RESEARCH
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- (2008) Kun Yang et al. JOURNAL OF NEURAL TRANSMISSION
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