Activation of NRF2 by Nitrosative Agents and H2O2Involves KEAP1 Disulfide Formation

Cul3-mediated Nrf2 ubiquitination and antioxidant response element (ARE) activation are dependent on the partial molar volume at position 151 of Keap1

(2009) Aimee L. Eggler et al.   BIOCHEMICAL JOURNAL

Crystal structure of the Bach1 BTB domain and its regulation of homodimerization

(2009) Nobutoshi Ito et al.   GENES TO CELLS

Cysteine-based regulation of the CUL3 adaptor protein Keap1

(2009) Konjeti R. Sekhar et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer

(2009) John D. Hayes et al.   TRENDS IN BIOCHEMICAL SCIENCES

Accumulation of 15-deoxy-Δ12,14-prostaglandin J2adduct formation with Keap1 over time: effects on potency for intracellular antioxidant defence induction

(2008) Joo Yeun Oh et al.   BIOCHEMICAL JOURNAL

Prospective Type 1 and Type 2 Disulfides of Keap1 Protein

(2008) Ryan Holland et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Covalent Modification at Cys151 Dissociates the Electrophile Sensor Keap1 from the Ubiquitin Ligase CUL3

(2008) Girish Rachakonda et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Physiological Significance of Reactive Cysteine Residues of Keap1 in Determining Nrf2 Activity

(2008) T. Yamamoto et al.   MOLECULAR AND CELLULAR BIOLOGY

The Antioxidant Defense System Keap1-Nrf2 Comprises a Multiple Sensing Mechanism for Responding to a Wide Range of Chemical Compounds

(2008) M. Kobayashi et al.   MOLECULAR AND CELLULAR BIOLOGY

Identification of Nrf2-dependent airway epithelial adaptive response to proinflammatory oxidant-hypochlorous acid challenge by transcription profiling

(2007) Lingxiang Zhu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Keap1 modification and nuclear accumulation in response to S-nitrosocysteine

(2007) Barbara J. Buckley et al.   FREE RADICAL BIOLOGY AND MEDICINE

Carnosic acid, acatechol-typeelectrophilic compound, protects neurons bothin vitroandin vivothrough activation of the Keap1/Nrf2 pathway viaS-alkylation of targeted cysteines on Keap1

(2007) Takumi Satoh et al.   JOURNAL OF NEUROCHEMISTRY

Negative feedback regulation of lipopolysaccharide-induced inducible nitric oxide synthase gene expression by heme oxygenase-1 induction in macrophages

(2007) Takashi Ashino et al.   MOLECULAR IMMUNOLOGY