Differential Proteome Profiling Analysis under Pesticide Stress by the Use of a Nano-UHPLC-MS/MS Untargeted Proteomic-Based Approach on a 3D-Developed Neurospheroid Model: Identification of Protein Interactions, Prognostic Biomarkers, and Potential Therapeutic Targets in Human IDH Mutant High-Grade Gliomas

Quantitative proteomic analysis of GnRH agonist treated GBM cell line LN229 revealed regulatory proteins inhibiting cancer cell proliferation

(2022) Priyanka H. Tripathi et al.   BMC CANCER

A Common Feature of Pesticides: Oxidative Stress—The Role of Oxidative Stress in Pesticide-Induced Toxicity

(2022) Rasheed O. Sule et al.   Oxidative Medicine and Cellular Longevity

Neuroserpin, a crucial regulator for axogenesis, synaptic modelling and cell–cell interactions in the pathophysiology of neurological disease

(2022) Angela Godinez et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Gene Expression Profiling of Glioblastoma to Recognize Potential Biomarker Candidates

(2022) Qiang Li et al.   Frontiers in Genetics

Targeting SREBP-1-Mediated Lipogenesis as Potential Strategies for Cancer

(2022) Qiushi Zhao et al.   Frontiers in Oncology

Expression and Prognostic Significance of Stem Cell Marker CD133 in Survival Rate of Patients with Colon Cancer

(2022) Hassan Ehteram et al.   Oncology and Therapy

Azathioprine antagonizes aberrantly elevated lipid metabolism and induces apoptosis in glioblastoma

(2021) Hye Jin Nam et al.   iScience

Lipid metabolism in cancer: New perspectives and emerging mechanisms

(2021) Lindsay A. Broadfield et al.   DEVELOPMENTAL CELL

The Role of NRF2/KEAP1 Signaling Pathway in Cancer Metabolism

(2021) Moon-Young Song et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Keap1-Nrf2 System: A Mediator between Oxidative Stress and Aging

(2021) Chao Yu et al.   Oxidative Medicine and Cellular Longevity

Immunoglobulin Expression in Cancer Cells and Its Critical Roles in Tumorigenesis

(2021) Ming Cui et al.   Frontiers in Immunology

The dysregulated expression and functional effect of CaMK2 in cancer

(2021) Qi He et al.   Cancer Cell International

Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis

(2021) Ruilin Tian et al.   NATURE NEUROSCIENCE

The 2021 WHO Classification of Tumors of the Central Nervous System: a summary

(2021) David N Louis et al.   NEURO-ONCOLOGY

Calcium-/Calmodulin-Dependent Protein Kinase II (CaMKII) Inhibition Induces Learning and Memory Impairment and Apoptosis

(2021) Jialu Wang et al.   Oxidative Medicine and Cellular Longevity

SERPINE2 Overexpression Is Associated with Poor Prognosis of Urothelial Carcinoma

(2021) Hao-Wen Chuang et al.   Diagnostics

The Role of Calmodulin in Tumor Cell Migration, Invasiveness, and Metastasis

(2020) Antonio Villalobo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

IDH mutation in glioma: molecular mechanisms and potential therapeutic targets

(2020) Sue Han et al.   BRITISH JOURNAL OF CANCER

Metabolic disturbance in hippocampus and liver of mice: A primary response to imidacloprid exposure

(2020) Meilin Zheng et al.   Scientific Reports

Endocytosis: a pivotal pathway for regulating metastasis

(2020) Imran Khan et al.   BRITISH JOURNAL OF CANCER

The Roles of Matrix Metalloproteinases and Their Inhibitors in Human Diseases

(2020) Griselda A Cabral-Pacheco et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Consequences of IDH1/2 Mutations in Gliomas and an Assessment of Inhibitors Targeting Mutated IDH Proteins

(2019) Bozena Kaminska et al.   MOLECULES

Spotlight on 17-AAG as an Hsp90 inhibitor for molecular targeted cancer treatment

(2019) Sona Talaei et al.   Chemical Biology & Drug Design

Proteomic Analysis Implicates Vimentin in Glioblastoma Cell Migration

(2019) Michal Nowicki et al.   Cancers

The Role of Cysteine Cathepsins in Cancer Progression and Drug Resistance

(2019) Magdalena Rudzińska et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Metascape provides a biologist-oriented resource for the analysis of systems-level datasets

(2019) Yingyao Zhou et al.   Nature Communications

Lambda-cyhalothrin exposure alters purine nucleotide hydrolysis and nucleotidase gene expression pattern in platelets and liver of rats

(2019) Bakhta Aouey et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Identification of SERPINE1 as a Regulator of Glioblastoma Cell Dispersal with Transcriptome Profiling

(2019) Fidan Seker et al.   Cancers

A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity

(2019) Fadi Jacob et al.   CELL

Nonoccupational Exposure of Agricultural Area Residents to Pesticides: Pesticide Accumulation and Evaluation of Genotoxicity

(2018) Zeynep Banu Doğanlar et al.   ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY

Apoptosis: A Target for Anticancer Therapy

(2018) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

High Expression of Vimentin is Associated With Progression and a Poor Outcome in Glioblastoma

(2018) Jiaxin Zhao et al.   APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY

Bioactive Lipids and Chronic Inflammation: Managing the Fire Within

(2018) Valerio Chiurchiù et al.   Frontiers in Immunology

Overexpression of the Kininogen-1 inhibits proliferation and induces apoptosis of glioma cells

(2018) Jinfang Xu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Bioactive lysolipids in cancer and angiogenesis

(2018) Yu Hisano et al.   PHARMACOLOGY & THERAPEUTICS

Glioblastoma Treatments: An Account of Recent Industrial Developments

(2018) Edouard Alphandéry   Frontiers in Pharmacology

Multidrug resistance in glioblastoma stem-like cells: Role of the hypoxic microenvironment and adenosine signaling

(2017) Daniel Uribe et al.   MOLECULAR ASPECTS OF MEDICINE

SREBP-regulated lipid metabolism: convergent physiology — divergent pathophysiology

(2017) Hitoshi Shimano et al.   Nature Reviews Endocrinology

Endoplasmic reticulum proteostasis in glioblastoma—From molecular mechanisms to therapeutic perspectives

(2017) Joanna Obacz et al.   Science Signaling

Pyrethroid Insecticide Cypermethrin Modulates Gonadotropin Synthesis via Calcium Homeostasis and ERK1/2 Signaling in LβT2 Mouse Pituitary Cells

(2017) Feixue Li et al.   TOXICOLOGICAL SCIENCES

Expression of nestin, cd133 and sox2 in meningiomas

(2017) Xiao Zong-yu et al.   Turkish Neurosurgery

The cholesterol metabolite 27 hydroxycholesterol facilitates breast cancer metastasis through its actions on immune cells

(2017) Amy E. Baek et al.   Nature Communications

Endoplasmic reticulum proteostasis in glioblastoma—From molecular mechanisms to therapeutic perspectives

(2017) Joanna Obacz et al.   Science Signaling

Inhibition of Human Drug Transporter Activities by the Pyrethroid Pesticides Allethrin and Tetramethrin

(2017) Lisa Chedik et al.   PLoS One

The endoplasmic reticulum stress/unfolded protein response in gliomagenesis, tumor progression and as a therapeutic target in glioblastoma

(2016) Natalia M. Peñaranda Fajardo et al.   BIOCHEMICAL PHARMACOLOGY

Long-term exposure of rabbits to imidaclorpid as quantified in blood induces genotoxic effect

(2016) Polychronis D. Stivaktakis et al.   CHEMOSPHERE

Fatostatin Inhibits Cancer Cell Proliferation by Affecting Mitotic Microtubule Spindle Assembly and Cell Division

(2016) Ankur A. Gholkar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Occupational pesticide exposure and adverse health effects at the clinical, hematological and biochemical level

(2016) Carmen R. García-García et al.   LIFE SCIENCES

The Keap1-Nrf2-ARE Pathway As a Potential Preventive and Therapeutic Target: An Update

(2016) Meng-Chen Lu et al.   MEDICINAL RESEARCH REVIEWS

Human astrocytes secrete IL-6 to promote glioma migration and invasion through upregulation of cytomembrane MMP14

(2016) Weiliang Chen et al.   Oncotarget

3D tumor spheroid models for in vitro therapeutic screening: a systematic approach to enhance the biological relevance of data obtained

(2016) Michele Zanoni et al.   Scientific Reports

Nestin as a marker of cancer stem cells

(2015) Jakub Neradil et al.   CANCER SCIENCE

Toxicity of mixtures of λ-cyhalothrin, imidacloprid and cadmium on the earthworm Eisenia fetida by combination index (CI)-isobologram method

(2015) Yanhua Wang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Class III β-tubulin in normal and cancer tissues

(2015) Marisa Mariani et al.   GENE

A Time to Kill: Targeting Apoptosis in Cancer

(2015) Jean Koff et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Redox proteomics identification of specifically carbonylated proteins in the hippocampi of triple transgenic Alzheimer's disease mice at its earliest pathological stage

(2015) Liming Shen et al.   Journal of Proteomics

Heat Shock Proteins: A Review of the Molecular Chaperones for Plant Immunity

(2015) Chang-Jin Park et al.   Plant Pathology Journal

Anti-cancer efficacy of SREBP inhibitor, alone or in combination with docetaxel, in prostate cancer harboring p53 mutations

(2015) Xiangyan Li et al.   Oncotarget

Determination of protein carbonyls in plasma, cell extracts, tissue homogenates, isolated proteins: Focus on sample preparation and derivatization conditions

(2015) Daniela Weber et al.   Redox Biology

Targeting SREBP-1-driven Lipid Metabolism to Treat Cancer

(2015) Deliang Guo et al.   CURRENT PHARMACEUTICAL DESIGN

Calmodulin antagonists induce cell cycle arrest and apoptosis in vitro and inhibit tumor growth in vivo in human multiple myeloma

(2014) Shigeyuki Yokokura et al.   BMC CANCER

Immunohistochemical analysis of GFAP-δ and nestin in cerebral astrocytomas

(2014) Felix Mircea Brehar et al.   Brain Tumor Pathology

Sox2 Is Required to Maintain Cancer Stem Cells in a Mouse Model of High-Grade Oligodendroglioma

(2014) Rebecca Favaro et al.   CANCER RESEARCH

SREBP-1 Has a Prognostic Role and Contributes to Invasion and Metastasis in Human Hepatocellular Carcinoma

(2014) Chao Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

In vitro Analysis of Neurospheres Derived from Glioblastoma Primary Culture: A Novel Methodology Paradigm

(2014) Lorena Favaro Pavon et al.   Frontiers in Neurology

CluePedia Cytoscape plugin: pathway insights using integrated experimental and in silico data

(2013) Gabriela Bindea et al.   BIOINFORMATICS

Deltamethrin-Induced [Ca2+ ]i Rise and Death in HGB Human Glioblastoma Cells

(2013)   CHINESE JOURNAL OF PHYSIOLOGY

Effect of the pesticide, deltamethrin, on Ca2+signaling and apoptosis in OC2 human oral cancer cells

(2013) Chao-Chuan Chi et al.   DRUG AND CHEMICAL TOXICOLOGY

Patient-Specific Orthotopic Glioblastoma Xenograft Models Recapitulate the Histopathology and Biology of Human Glioblastomas In Situ

(2013) Kyeung Min Joo et al.   Cell Reports

Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation

(2012) Maria Vinci et al.   BMC BIOLOGY

α-Enolase, a Multifunctional Protein: Its Role on Pathophysiological Situations

(2012) Àngels Díaz-Ramos et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

LC-MS/MS Analysis of Differentially Expressed Glioblastoma Membrane Proteome Reveals Altered Calcium Signaling and Other Protein Groups of Regulatory Functions

(2012) Ravindra Varma Polisetty et al.   MOLECULAR & CELLULAR PROTEOMICS

Breast cancer resistance protein (BCRP/ABCG2) localises to the nucleus in glioblastoma multiforme cells

(2012) Prateek Bhatia et al.   XENOBIOTICA

Cancer Cell Metabolism: One Hallmark, Many Faces

(2012) Jason R. Cantor et al.   Cancer Discovery

Molecular cross-talk between the NRF2/KEAP1 signaling pathway, autophagy, and apoptosis

(2011) Tomasz M. Stępkowski et al.   FREE RADICAL BIOLOGY AND MEDICINE

Protein alterations associated with temozolomide resistance in subclones of human glioblastoma cell lines

(2011) Stella Sun et al.   JOURNAL OF NEURO-ONCOLOGY

An in vivo patient-derived model of endogenous IDH1-mutant glioma

(2011) H. A. Luchman et al.   NEURO-ONCOLOGY

Pathological roles of MAPK signaling pathways in human diseases

(2010) Eun Kyung Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Proteomic Identification of Carbonylated Proteins and Their Oxidation Sites

(2010) Ashraf G. Madian et al.   JOURNAL OF PROTEOME RESEARCH

Comprehensive Proteomic Analysis of the Effects of Purine Analogs on Human Raji B-Cell Lymphoma

(2010) Swetlana Mactier et al.   JOURNAL OF PROTEOME RESEARCH

Glioma proteomics: Status and perspectives

(2010) Simone P. Niclou et al.   Journal of Proteomics

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

(2009) Gabriela Bindea et al.   BIOINFORMATICS

Life and death by death receptors

(2009) Maria Eugenia Guicciardi et al.   FASEB JOURNAL

Spheroid-based drug screen: considerations and practical approach

(2009) Juergen Friedrich et al.   Nature Protocols

Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment

(2009) G. Bertolini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxidative stress induces gastric epithelial permeability through claudin-3

(2008) Kayo Hashimoto et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cancer stem cells in multiple myeloma

(2008) Nilanjan Ghosh et al.   CANCER LETTERS

Cystatin F is a cathepsin C-directed protease inhibitor regulated by proteolysis

(2008) Garth Hamilton et al.   EMBO JOURNAL

The role of annexins in tumour development and progression

(2008) S Mussunoor et al.   JOURNAL OF PATHOLOGY

Identification of cells initiating human melanomas

(2008) Tobias Schatton et al.   NATURE

Bcl2L12-mediated inhibition of effector caspase-3 and caspase-7 via distinct mechanisms in glioblastoma

(2008) A. H. Stegh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA