Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation

Morphological and cytoskeletal changes of pancreatic cancer cells in three-dimensional spheroidal culture

(2011) Yoko Matsuda et al.   Medical Molecular Morphology

High drug attrition rates—where are we going wrong?

(2011) Lisa Hutchinson et al.   Nature Reviews Clinical Oncology

The Development and Characterization of a Human Mesothelioma In Vitro 3D Model to Investigate Immunotoxin Therapy

(2011) Xinran Xiang et al.   PLoS One

Secretion of extracellular hsp90α via exosomes increases cancer cell motility: a role for plasminogen activation

(2010) Jessica McCready et al.   BMC CANCER

In situ protein expression in tumour spheres: development of an immunostaining protocol for confocal microscopy

(2010) Louis-Bastien Weiswald et al.   BMC CANCER

The plasticity of cytoskeletal dynamics underlying neoplastic cell migration

(2010) Victoria Sanz-Moreno et al.   CURRENT OPINION IN CELL BIOLOGY

Multicellular tumor spheroids: An underestimated tool is catching up again

(2010) Franziska Hirschhaeuser et al.   JOURNAL OF BIOTECHNOLOGY

Microarrays for the scalable production of metabolically relevant tumour spheroids: a tool for modulating chemosensitivity traits

(2010) Heike Hardelauf et al.   LAB ON A CHIP

A Comprehensive Panel of Three-Dimensional Models for Studies of Prostate Cancer Growth, Invasion and Drug Responses

(2010) Ville Härmä et al.   PLoS One

Collective Cell Migration

(2009) Pernille Rørth   Annual Review of Cell and Developmental Biology

Genomic and Expression Profiling of Glioblastoma Stem Cell-Like Spheroid Cultures Identifies Novel Tumor-Relevant Genes Associated with Survival

(2009) A. Ernst et al.   CLINICAL CANCER RESEARCH

Aurora kinases as prognostic biomarkers in ovarian carcinoma

(2009) Marta Mendiola et al.   HUMAN PATHOLOGY

Mechanisms of collective cell migration at a glance

(2009) O. Ilina et al.   JOURNAL OF CELL SCIENCE

Spheroid-based drug screen: considerations and practical approach

(2009) Juergen Friedrich et al.   Nature Protocols

Molecular and Phenotypic Characterisation of Paediatric Glioma Cell Lines as Models for Preclinical Drug Development

(2009) Dorine A. Bax et al.   PLoS One

Identification of Gastric Cancer Stem Cells Using the Cell Surface Marker CD44

(2009) Shigeo Takaishi et al.   STEM CELLS

Modelling tissues in 3D: the next future of pharmaco-toxicology and food research?

(2008) Giovanna Mazzoleni et al.   Genes and Nutrition

Compact spheroid formation by ovarian cancer cells is associated with contractile behavior and an invasive phenotype

(2008) Katharine L. Sodek et al.   INTERNATIONAL JOURNAL OF CANCER

Invadopodia: At the cutting edge of tumour invasion

(2008) Stanley S. Stylli et al.   JOURNAL OF CLINICAL NEUROSCIENCE