Fatostatin Inhibits Cancer Cell Proliferation by Affecting Mitotic Microtubule Spindle Assembly and Cell Division

The X-Linked-Intellectual-Disability-Associated Ubiquitin Ligase Mid2 Interacts with Astrin and Regulates Astrin Levels to Promote Cell Division

(2016) Ankur A. Gholkar et al.   Cell Reports

Cholesterol lowering: role in cancer prevention and treatment

(2015) Toshiyuki Murai   BIOLOGICAL CHEMISTRY

Targeting SREBPs for treatment of the metabolic syndrome

(2015) Selma M. Soyal et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Large-Scale Chemical Similarity Networks for Target Profiling of Compounds Identified in Cell-Based Chemical Screens

(2015) Yu-Chen Lo et al.   PLoS Computational Biology

Targeting SREBP-1-driven Lipid Metabolism to Treat Cancer

(2015) Deliang Guo et al.   CURRENT PHARMACEUTICAL DESIGN

Tumor-Induced Alterations in Lipid Metabolism

(2014) M. Notarnicola et al.   CURRENT MEDICINAL CHEMISTRY

Fatostatin Displays High Antitumor Activity in Prostate Cancer by Blocking SREBP-Regulated Metabolic Pathways and Androgen Receptor Signaling

(2014) X. Li et al.   MOLECULAR CANCER THERAPEUTICS

Chemical dissection of the cell cycle: probes for cell biology and anti-cancer drug development

(2014) S Senese et al.   Cell Death & Disease

An Essential Requirement for the SCAP/SREBP Signaling Axis to Protect Cancer Cells from Lipotoxicity

(2013) K. J. Williams et al.   CANCER RESEARCH

GSI promotes vincristine-induced apoptosis by enhancing multi-polar spindle formation

(2013) Akannsha Singh et al.   CELL CYCLE

Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate

(2012) Patrick S. Ward et al.   CANCER CELL

Inhibition of SREBP by a Small Molecule, Betulin, Improves Hyperlipidemia and Insulin Resistance and Reduces Atherosclerotic Plaques

(2011) Jing-Jie Tang et al.   Cell Metabolism

A Specific Form of Phospho Protein Phosphatase 2 Regulates Anaphase-promoting Complex/Cyclosome Association with Spindle Poles

(2010) Jorge Z. Torres et al.   MOLECULAR BIOLOGY OF THE CELL

A Small Molecule That Blocks Fat Synthesis By Inhibiting the Activation of SREBP

(2009) Shinji Kamisuki et al.   CHEMISTRY & BIOLOGY

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation

(2008) Ralph J. DeBerardinis et al.   Cell Metabolism

Pharmacologic Inhibition of Site 1 Protease Activity Inhibits Sterol Regulatory Element-Binding Protein Processing and Reduces Lipogenic Enzyme Gene Expression and Lipid Synthesis in Cultured Cells and Experimental Animals

(2008) J. L. Hawkins et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS