The Alternating Access Mechanism in Mammalian Multidrug Resistance Transporters and Their Bacterial Homologs
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The Alternating Access Mechanism in Mammalian Multidrug Resistance Transporters and Their Bacterial Homologs
Authors
Keywords
-
Journal
Membranes
Volume 13, Issue 6, Pages 568
Publisher
MDPI AG
Online
2023-05-31
DOI
10.3390/membranes13060568
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- A Structure-Based View on ABC-Transporter Linked to Multidrug Resistance
- (2023) Jiahui Huang et al. MOLECULES
- On the interplay between lipids and asymmetric dynamics of an NBS degenerate ABC transporter
- (2023) Ágota Tóth et al. Communications Biology
- Overcoming Cancer Multi-drug Resistance (MDR): Reasons, mechanisms, nanotherapeutic solutions, and challenges
- (2023) Chunyan Duan et al. BIOMEDICINE & PHARMACOTHERAPY
- ATP-binding cassette efflux transporters and MDR in cancer
- (2023) Manasi S. Pote et al. DRUG DISCOVERY TODAY
- A macrocyclic peptide inhibitor traps MRP1 in a catalytically incompetent conformation
- (2023) Harlan L. Pietz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The culmination of multidrug-resistant efflux pumps vs. meager antibiotic arsenal era: Urgent need for an improved new generation of EPIs
- (2023) Shiela Chetri Frontiers in Microbiology
- Inhibition of Multidrug Efflux Pumps Belonging to the Major Facilitator Superfamily in Bacterial Pathogens
- (2023) Manuel F. Varela et al. Biomedicines
- Refinement of safety and efficacy of anti-cancer chemotherapeutics by tailoring their site-specific intracellular bioavailability through transporter modulation
- (2023) Pooja Dhakne et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Conformational trapping of an ABC transporter in polymer lipid nanoparticles
- (2022) Naomi L. Pollock et al. BIOCHEMICAL JOURNAL
- GSH facilitates the binding and inhibitory activity of novel multidrug resistance protein 1 (MRP1) modulators
- (2022) Kimberley M. Hanssen et al. FEBS Journal
- Multidrug Resistance (MDR): A Widespread Phenomenon in Pharmacological Therapies
- (2022) Alessia Catalano et al. MOLECULES
- Prefusion spike protein conformational changes are slower in SARS-CoV-2 than in SARS-CoV-1
- (2022) Vivek Govind Kumar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The structural basis for regulation of the glutathione transporter Ycf1 by regulatory domain phosphorylation
- (2022) Nitesh Kumar Khandelwal et al. Nature Communications
- Bacterial Multidrug Efflux Pumps at the Frontline of Antimicrobial Resistance: An Overview
- (2022) Lulu Huang et al. Antibiotics-Basel
- Efflux dynamics of the antiseizure drug, levetiracetam, through the P-glycoprotein channel revealed by advanced comparative molecular simulations
- (2022) Esmaeil Behmard et al. Scientific Reports
- Transporter Regulation in Critical Protective Barriers: Focus on Brain and Placenta
- (2022) Valerio Taggi et al. Pharmaceutics
- Multidrug Resistance of Cancer Cells and the Vital Role of P-Glycoprotein
- (2022) Chenmala Karthika et al. Life-Basel
- The role of bacterial ATP-binding cassette (ABC) transporters in pathogenesis and virulence: Therapeutic and vaccine potential
- (2022) Armaan A. Akhtar et al. MICROBIAL PATHOGENESIS
- Proton-driven alternating access in a spinster lipid transporter
- (2022) Reza Dastvan et al. Nature Communications
- Regulation of P-Glycoprotein in the Brain
- (2022) Amanda B. Chai et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Structural basis for lipid and copper regulation of the ABC transporter MsbA
- (2022) Jixing Lyu et al. Nature Communications
- Structural dynamics of ABC transporters: molecular simulation studies
- (2021) Tadaomi Furuta BIOCHEMICAL SOCIETY TRANSACTIONS
- Conserved amino acids in the region connecting membrane spanning domain 1 to nucleotide binding domain 1 are essential for expression of the MRP1 (ABCC1) transporter
- (2021) Emma E. Smith et al. PLoS One
- Structures and General Transport Mechanisms by the Major Facilitator Superfamily (MFS)
- (2021) David Drew et al. CHEMICAL REVIEWS
- Pleiotropic Roles of ABC Transporters in Breast Cancer
- (2021) Ji He et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Structural Insights into Transporter-Mediated Drug Resistance in Infectious Diseases
- (2021) Jonathan Kim et al. JOURNAL OF MOLECULAR BIOLOGY
- Bacteriophage therapy for inhibition of multi drug‐resistant uropathogenic bacteria: a narrative review
- (2021) Zahra Chegini et al. Annals of Clinical Microbiology and Antimicrobials
- Clinically-Relevant ABC Transporter for Anti-Cancer Drug Resistance
- (2021) Huan Xiao et al. Frontiers in Pharmacology
- Effect of the Force Field on Molecular Dynamics Simulations of the Multidrug Efflux Protein P-Glycoprotein
- (2021) Lily Wang et al. Journal of Chemical Theory and Computation
- Pharmaceutical Formulations with P-Glycoprotein Inhibitory Effect as Promising Approaches for Enhancing Oral Drug Absorption and Bioavailability
- (2021) Thi-Thao-Linh Nguyen et al. Pharmaceutics
- Overcoming Multidrug Resistance in Bacteria Through Antibiotics Delivery in Surface-Engineered Nano-Cargos: Recent Developments for Future Nano-Antibiotics
- (2021) Xinfu Yang et al. Frontiers in Bioengineering and Biotechnology
- ATP‐binding cassette (ABC) transporters in cancer: A review of recent updates
- (2021) Jing‐Quan Wang et al. Journal of Evidence-Based Medicine
- Structure–Function Relationships in the Human P-Glycoprotein (ABCB1): Insights from Molecular Dynamics Simulations
- (2021) Liadys Mora Lagares et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Computational binding affinity and molecular dynamic characterization of annonaceous acetogenins at nucleotide binding domain (NBD) of multi-drug resistance ATP-binding cassette sub-family B member 1 (ABCB1)
- (2021) Jeevitha Priya Manoharan et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Discovery and Characterization of Potent Dual P-Glycoprotein and CYP3A4 Inhibitors: Design, Synthesis, Cryo-EM Analysis, and Biological Evaluations
- (2021) Sameer Urgaonkar et al. JOURNAL OF MEDICINAL CHEMISTRY
- Virulence Potential and Treatment Options of Multidrug-Resistant (MDR) Acinetobacter baumannii
- (2021) Sunil Kumar et al. Microorganisms
- Efflux Pump Mediated Antimicrobial Resistance by Staphylococci in Health-Related Environments: Challenges and the Quest for Inhibition
- (2021) Abolfazl Dashtbani-Roozbehani et al. Antibiotics-Basel
- In vivo FRET analyses reveal a role of ATP hydrolysis–associated conformational changes in human P-glycoprotein
- (2020) Ryota Futamata et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Sequence and structural determinants of ligand-dependent alternating access of a MATE transporter
- (2020) Kevin L. Jagessar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- New approach for membrane protein reconstitution into peptidiscs and basis for their adaptability to different proteins
- (2020) Gabriella Angiulli et al. eLife
- Multidrug-Resistant Bacterial Infections in U.S. Hospitalized Patients, 2012–2017
- (2020) John A. Jernigan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Dysfunction of ABC transporters at the blood-brain barrier: Role in neurological disorders
- (2020) Eva Gil-Martins et al. PHARMACOLOGY & THERAPEUTICS
- Cryo-electron Microscopy Structure and Transport Mechanism of a Wall Teichoic Acid ABC Transporter
- (2020) Li Chen et al. mBio
- Characterization of the kinetic cycle of an ABC transporter by single-molecule and cryo-EM analyses
- (2020) Ling Wang et al. eLife
- High-resolution views of lipopolysaccharide translocation driven by ABC transporters MsbA and LptB2FGC
- (2020) François Thélot et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Combining Machine Learning and Molecular Dynamics to Predict P-Glycoprotein Substrates
- (2020) Carmen Esposito et al. Journal of Chemical Information and Modeling
- Cross-linking, DEER-spectroscopy and molecular dynamics confirm the inward facing state of P-glycoprotein in a lipid membrane
- (2020) Alex R. Carey Hulyer et al. JOURNAL OF STRUCTURAL BIOLOGY
- Capturing Substrate Translocation in an ABC Exporter at the Atomic Level
- (2020) Hendrik Göddeke et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein
- (2020) Christina A. Le et al. IUCrJ
- Mamma Mia, P‐glycoprotein binds again
- (2020) Richard Callaghan et al. FEBS LETTERS
- Structural and functional diversity calls for a new classification of ABC transporters
- (2020) Christoph Thomas et al. FEBS LETTERS
- Theoretical Insights into the Cotransport Mechanism of GSH with Anticancer Drugs by MRP1
- (2020) Zi-Jing Zhao et al. JOURNAL OF PHYSICAL CHEMISTRY B
- P-Glycoprotein: One Mechanism, Many Tasks and the Consequences for Pharmacotherapy of Cancers
- (2020) Anna Seelig Frontiers in Oncology
- Cholesterol Asymmetrically Modulates the Conformational Ensemble of the Nucleotide-Binding Domains of P-Glycoprotein in Lipid Nanodiscs
- (2020) Amanda F. Clouser et al. BIOCHEMISTRY
- Structural and Functional Diversity of Resistance–Nodulation–Cell Division Transporters
- (2020) Philip A. Klenotic et al. CHEMICAL REVIEWS
- Structure and Function of Hepatobiliary ATP Binding Cassette Transporters
- (2020) Tim Kroll et al. CHEMICAL REVIEWS
- The role of the degenerate nucleotide binding site in type I ABC exporters
- (2020) Thomas Stockner et al. FEBS LETTERS
- Computational Insights into Allosteric Conformational Modulation of P-Glycoprotein by Substrate and Inhibitor Binding
- (2020) Juan Xing et al. MOLECULES
- The Role of ATP-binding Cassette (ABC) Transporters in Bacterial Phytopathogenesis
- (2020) Yuan Zeng et al. PHYTOPATHOLOGY
- Learning the ABCs one at a time: structure and mechanism of ABC transporters
- (2019) Robert C. Ford et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Inward- and outward-facing X-ray crystal structures of homodimeric P-glycoprotein CmABCB1
- (2019) Atsushi Kodan et al. Nature Communications
- Lipid-Dependent Alternating Access Mechanism of a Bacterial Multidrug ABC Exporter
- (2019) Kalyan Immadisetty et al. ACS Central Science
- Gaseous signaling molecules and their application in resistant cancer treatment: from invisible to visible
- (2019) Qingbin Cui et al. Future Medicinal Chemistry
- Mechanism of allosteric modulation of P-glycoprotein by transport substrates and inhibitors
- (2019) Reza Dastvan et al. SCIENCE
- Structural Insights into the Lipid A Transport Pathway in MsbA
- (2019) Pius S. Padayatti et al. STRUCTURE
- Structure-guided probing of the leukotriene C4 binding site in human multidrug resistance protein 1 (MRP1; ABCC1)
- (2019) Gwenaëlle Conseil et al. FASEB JOURNAL
- Multidrug ABC transporters in bacteria
- (2019) Cédric Orelle et al. RESEARCH IN MICROBIOLOGY
- Mechanics and pharmacology of substrate selection and transport by eukaryotic ABC exporters
- (2019) Sriram Srikant et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The Varied Role of Efflux Pumps of the MFS Family in the Interplay of Bacteria with Animal and Plant Cells
- (2019) Pasqua et al. Microorganisms
- Structural biology of the multidrug and toxic compound extrusion superfamily transporters
- (2019) Tsukasa Kusakizako et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Probing cholesterol binding and translocation in P-glycoprotein
- (2019) Sundar Thangapandian et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- The effect of drug binding on specific sites in transmembrane helices 4 and 6 of the ABC exporter MsbA studied by DNP-enhanced solid-state NMR
- (2018) Roberta Spadaccini et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- ATP Binding Enables Substrate Release from Multidrug Resistance Protein 1
- (2018) Zachary Lee Johnson et al. CELL
- Modulation of Hepatic MRP3/ABCC3 by Xenobiotics and Pathophysiological Conditions: Role in Drug Pharmacokinetics.
- (2018) Carolina I. Ghanem et al. CURRENT MEDICINAL CHEMISTRY
- Exploring movement and energy in human P-glycoprotein conformational rearrangement
- (2018) Yue Zhang et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Multiscale molecular dynamics simulations of lipid interactions with P-glycoprotein in a complex membrane
- (2018) Laura Domicevica et al. JOURNAL OF MOLECULAR GRAPHICS & MODELLING
- Atomistic Mechanism of Large-Scale Conformational Transition in a Heterodimeric ABC Exporter
- (2018) Hendrik Göddeke et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- An Outward-facing Aromatic Amino Acid is Crucial for Signalling Between the Membrane Spanning and Nucleotide Binding Domains of Multidrug Resistance Protein 1 (MRP1; ABCC1)
- (2018) Kevin E. Weigl et al. MOLECULAR PHARMACOLOGY
- Architecture of a channel-forming O-antigen polysaccharide ABC transporter
- (2018) Yunchen Bi et al. NATURE
- Multidrug efflux pumps: structure, function and regulation
- (2018) Dijun Du et al. NATURE REVIEWS MICROBIOLOGY
- Molecular structure of human P-glycoprotein in the ATP-bound, outward-facing conformation
- (2018) Youngjin Kim et al. SCIENCE
- Structure of a MacAB-like efflux pump from Streptococcus pneumoniae
- (2018) Hong-Bo Yang et al. Nature Communications
- Targeted inhibitors of P-glycoprotein increase chemotherapeutic-induced mortality of multidrug resistant tumor cells
- (2018) Amila K. Nanayakkara et al. Scientific Reports
- Antibiotic Resistance Mediated by the MacB ABC Transporter Family: A Structural and Functional Perspective
- (2018) Nicholas P. Greene et al. Frontiers in Microbiology
- Neurosteroid Transport in the Brain: Role of ABC and SLC Transporters
- (2018) Markus Grube et al. Frontiers in Pharmacology
- Structural basis for dual-mode inhibition of the ABC transporter MsbA
- (2018) Hoangdung Ho et al. NATURE
- Unexplored Nucleotide Binding Modes for the ABC Exporter MsbA
- (2018) Hundeep Kaur et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Novel features in the structure of P-glycoprotein (ABCB1) in the post-hydrolytic state as determined at 7.9 Å resolution
- (2018) Nopnithi Thonghin et al. BMC STRUCTURAL BIOLOGY
- CircPAN3 mediates drug resistance in acute myeloid leukemia through the miR-153-5p/miR-183-5p–XIAP axis
- (2018) Jin Shang et al. EXPERIMENTAL HEMATOLOGY
- The role played by drug efflux pumps in bacterial multidrug resistance
- (2017) Mohsen Chitsaz et al. Essays in Biochemistry
- Inhibit or Evade Multidrug Resistance P-Glycoprotein in Cancer Treatment
- (2017) Deepali Waghray et al. JOURNAL OF MEDICINAL CHEMISTRY
- New Roads Leading to Old Destinations: Efflux Pumps as Targets to Reverse Multidrug Resistance in Bacteria
- (2017) Gabriella Spengler et al. MOLECULES
- Natural Products as Alternative Choices for P-Glycoprotein (P-gp) Inhibition
- (2017) Saikat Dewanjee et al. MOLECULES
- Structure of the human multidrug transporter ABCG2
- (2017) Nicholas M. I. Taylor et al. NATURE
- Structural basis of MsbA-mediated lipopolysaccharide transport
- (2017) Wei Mi et al. NATURE
- Energy transduction and alternating access of the mammalian ABC transporter P-glycoprotein
- (2017) Brandy Verhalen et al. NATURE
- Detection approaches for multidrug resistance genes of leukemia
- (2017) Ying Du et al. Drug Design Development and Therapy
- ATP-binding Cassette Exporters: Structure and Mechanism with a Focus on P-glycoprotein and MRP1
- (2017) Maite Rocío Arana et al. CURRENT MEDICINAL CHEMISTRY
- Cardiovascular Ion Channel Inhibitor Drug-Drug Interactions with P-glycoprotein
- (2016) Kaitlyn V. Ledwitch et al. AAPS Journal
- Shared Molecular Mechanisms of Membrane Transporters
- (2016) David Drew et al. Annual Review of Biochemistry
- Overcoming ABC transporter-mediated multidrug resistance: Molecular mechanisms and novel therapeutic drug strategies
- (2016) Wen Li et al. DRUG RESISTANCE UPDATES
- New insights into the roles of the N-terminal region of the ABCC6 transporter
- (2016) Rocchina Miglionico et al. JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
- Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity
- (2016) Lothar Esser et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mechanistic diversity in ATP-binding cassette (ABC) transporters
- (2016) Kaspar P Locher NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Redox Control of Multidrug Resistance and Its Possible Modulation by Antioxidants
- (2016) Aysegul Cort et al. Oxidative Medicine and Cellular Longevity
- Arabidopsis thaliana MRP1 (AtABCC1) nucleotide binding domain contributes to arsenic stress tolerance with serine triad phosphorylation
- (2016) Ayan Raichaudhuri PLANT PHYSIOLOGY AND BIOCHEMISTRY
- Coupled ATPase-adenylate kinase activity in ABC transporters
- (2016) Hundeep Kaur et al. Nature Communications
- Tripartite assembly of RND multidrug efflux pumps
- (2016) Laetitia Daury et al. Nature Communications
- Mechanistic diversity in ATP-binding cassette (ABC) transporters
- (2016) Kaspar P Locher NATURE STRUCTURAL & MOLECULAR BIOLOGY
- A single active catalytic site is sufficient to promote transport in P-glycoprotein
- (2016) Orsolya Bársony et al. Scientific Reports
- Global marine pollutants inhibit P-glycoprotein: Environmental levels, inhibitory effects, and cocrystal structure
- (2016) S. C. T. Nicklisch et al. Science Advances
- Multidrug Resistance Proteins (MRPs) and Cancer Therapy
- (2015) Yun-Kai Zhang et al. AAPS Journal
- Structural Biology of the Major Facilitator Superfamily Transporters
- (2015) Nieng Yan Annual Review of Biophysics
- Homology modelling of human P-glycoprotein
- (2015) L. Domicevica et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- ABC transporters in adaptive immunity
- (2015) Fabian Seyffer et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- The ABC exporter MsbA probed by solid state NMR – challenges and opportunities
- (2015) Hundeep Kaur et al. BIOLOGICAL CHEMISTRY
- miR-7 modulates chemoresistance of small cell lung cancer by repressing MRP1/ABCC1
- (2015) Huanxin Liu et al. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY
- Equilibrated Atomic Models of Outward-Facing P-glycoprotein and Effect of ATP Binding on Structural Dynamics
- (2015) Lurong Pan et al. Scientific Reports
- Tracing the structural evolution of eukaryotic ATP binding cassette transporter superfamily
- (2015) Jie Xiong et al. Scientific Reports
- Role of MRP transporters in regulating antimicrobial drug inefficacy and oxidative stress-induced pathogenesis during HIV-1 and TB infections
- (2015) Upal Roy et al. Frontiers in Microbiology
- Interaction of antibacterial compounds with RND efflux pumps in Pseudomonas aeruginosa
- (2015) Jürg Dreier et al. Frontiers in Microbiology
- Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein
- (2015) Paul Szewczyk et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Permeability Barrier of Gram-Negative Cell Envelopes and Approaches To Bypass It
- (2015) Helen I. Zgurskaya et al. ACS Infectious Diseases
- Analysis of the Structural and Functional Roles of Coupling Helices in the ATP-Binding Cassette Transporter MsbA through Enzyme Assays and Molecular Dynamics Simulations
- (2014) Tadaomi Furuta et al. BIOCHEMISTRY
- Translocation mechanism of P-glycoprotein and conformational changes occurring at drug-binding site: Insights from multi-targeted molecular dynamics
- (2014) Rameshwar Prajapati et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- The central cavity of ABCB1 undergoes alternating access during ATP hydrolysis
- (2014) Jessica H. van Wonderen et al. FEBS Journal
- Structural Characterization of the Drug Translocation Path of MRP1/ABCC1
- (2014) Shay Amram et al. ISRAEL JOURNAL OF CHEMISTRY
- Multidrug Resistance Protein 1 (MRP1, ABCC1), a “Multitasking” ATP-binding Cassette (ABC) Transporter
- (2014) Susan P. C. Cole JOURNAL OF BIOLOGICAL CHEMISTRY
- Computational Recipe for Efficient Description of Large-Scale Conformational Changes in Biomolecular Systems
- (2014) Mahmoud Moradi et al. Journal of Chemical Theory and Computation
- Structural basis for gating mechanisms of a eukaryotic P-glycoprotein homolog
- (2014) A. Kodan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Diversity in ATP concentrations in a single bacterial cell population revealed by quantitative single-cell imaging
- (2014) Hideyuki Yaginuma et al. Scientific Reports
- Conformational dynamics of the nucleotide binding domains and the power stroke of a heterodimeric ABC transporter
- (2014) Smriti Mishra et al. eLife
- Multidrug resistance: Physiological principles and nanomedical solutions
- (2013) Sijumon Kunjachan et al. ADVANCED DRUG DELIVERY REVIEWS
- Targeting Multidrug Resistance Protein 1 (MRP1, ABCC1): Past, Present, and Future
- (2013) Susan P.C. Cole Annual Review of Pharmacology and Toxicology
- A Salt Bridge in Intracellular Loop 2 Is Essential for Folding of Human P-Glycoprotein
- (2013) Tip W. Loo et al. BIOCHEMISTRY
- Human P-glycoprotein Contains a Greasy Ball-and-Socket Joint at the Second Transmission Interface
- (2013) Tip W. Loo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Molecular Disruption of the Power Stroke in the ATP-binding Cassette Transport Protein MsbA
- (2013) Rupak Doshi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- On the Origin of Large Flexibility of P-glycoprotein in the Inward-facing State
- (2013) Po-Chao Wen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- ATP and AMP Mutually Influence Their Interaction with the ATP-binding Cassette (ABC) Adenylate Kinase Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) at Separate Binding Sites
- (2013) Christoph O. Randak et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Molecular insight into conformational transmission of human P-glycoprotein
- (2013) Shan-Yan Chang et al. JOURNAL OF CHEMICAL PHYSICS
- In silico model for P-glycoprotein substrate prediction: insights from molecular dynamics and in vitro studies
- (2013) Rameshwar Prajapati et al. JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
- Structural insights into H+-coupled multidrug extrusion by a MATE transporter
- (2013) Min Lu et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Mechanistic picture for conformational transition of a membrane transporter at atomic resolution
- (2013) M. Moradi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain
- (2013) A. B. Ward et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Refined structures of mouse P-glycoprotein
- (2013) Jingzhi Li et al. PROTEIN SCIENCE
- P-glycoprotein is a marker of tissue eosinophilia and radiographic inflammation in chronic rhinosinusitis without nasal polyps
- (2013) Rachel E. Feldman et al. International Forum of Allergy & Rhinology
- Mechanisms and insights into drug resistance in cancer
- (2013) Hiba Zahreddine et al. Frontiers in Pharmacology
- Role of breast cancer resistance protein (BCRP/ABCG2) in cancer drug resistance
- (2012) Karthika Natarajan et al. BIOCHEMICAL PHARMACOLOGY
- Catalytic Transitions in the Human MDR1 P-Glycoprotein Drug Binding Sites
- (2012) John G. Wise BIOCHEMISTRY
- P-glycoprotein is fully active after multiple tryptophan substitutions
- (2012) Douglas J. Swartz et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Structural and Functional Properties of Human Multidrug Resistance Protein 1 (MRP1/ABCC1)
- (2012) S.-M. He et al. CURRENT MEDICINAL CHEMISTRY
- Twelve Transmembrane Helices Form the Functional Core of Mammalian MATE1 (Multidrug and Toxin Extruder 1) Protein
- (2012) Xiaohong Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Asymmetry in the Homodimeric ABC Transporter MsbA Recognized by a DARPin
- (2012) Anshumali Mittal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Insights on P-Glycoprotein’s Efflux Mechanism Obtained by Molecular Dynamics Simulations
- (2012) Ricardo J. Ferreira et al. Journal of Chemical Theory and Computation
- Molecular Dynamics Simulations of the Bacterial ABC Transporter SAV1866 in the Closed Form
- (2012) Jean-François St-Pierre et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation
- (2012) Michael Hohl et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Perspectives on the structure–function of ABC transporters: The Switch and Constant Contact Models
- (2012) Anthony M. George et al. PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
- Evolution of ABC transporters by gene duplication and their role in human disease
- (2011) Karobi Moitra et al. BIOLOGICAL CHEMISTRY
- Mammalian multidrug-resistance proteins (MRPs)
- (2011) Andrew J. Slot et al. Essays in Biochemistry
- Structure of ABC transporters
- (2011) Joseph K. Zolnerciks et al. Essays in Biochemistry
- The P-glycoprotein multidrug transporter
- (2011) Frances J. Sharom Essays in Biochemistry
- Conformational changes induced by ATP-hydrolysis in an ABC transporter: A molecular dynamics study of the Sav1866 exporter
- (2011) A. Sofia Oliveira et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Multidrug resistance associated proteins in multidrug resistance
- (2011) Kamlesh Sodani et al. Chinese Journal of Cancer
- The reconstitutedEscherichia coliMsbA protein displays lipid flippase activity
- (2010) Paul D. W. Eckford et al. BIOCHEMICAL JOURNAL
- Dynamics and Structural Changes Induced by ATP Binding in SAV1866, a Bacterial ABC Exporter
- (2010) Jean-Paul Becker et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Impact of the Recent Mouse P-Glycoprotein Structure for Structure-Based Ligand Design
- (2010) Freya Klepsch et al. Molecular Informatics
- Asymmetric Switching in a Homodimeric ABC Transporter: A Simulation Study
- (2010) Jussi Aittoniemi et al. PLoS Computational Biology
- Multidrug Resistance in Bacteria
- (2009) Hiroshi Nikaido Annual Review of Biochemistry
- The ABC transporter MsbA interacts with lipid A and amphipathic drugs at different sites
- (2009) Alena Siarheyeva et al. BIOCHEMICAL JOURNAL
- Efflux-Mediated Drug Resistance in Bacteria
- (2009) Xian-Zhi Li et al. DRUGS
- The mechanism of ABC transporters: general lessons from structural and functional studies of an antigenic peptide transporter
- (2009) Erik Procko et al. FASEB JOURNAL
- Prevention of seizure-induced up-regulation of endothelial P-glycoprotein by COX-2 inhibition
- (2009) Guido Zibell et al. NEUROPHARMACOLOGY
- The assembled structure of a complete tripartite bacterial multidrug efflux pump
- (2009) M. F. Symmons et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
- (2009) S. G. Aller et al. SCIENCE
- Functional Role of Transmembrane Helix 6 in Drug Binding and Transport by the ABC Transporter MsbA†
- (2008) Barbara Woebking et al. BIOCHEMISTRY
- Multidrug Transport by the ABC Transporter Sav1866 fromStaphylococcus aureus†
- (2008) Saroj Velamakanni et al. BIOCHEMISTRY
- Functionally Important ATP Binding and Hydrolysis Sites inEscherichia coliMsbA†
- (2008) Kathryn M. Westfahl et al. BIOCHEMISTRY
- Mechanisms of RND multidrug efflux pumps
- (2008) Hiroshi Nikaido et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Structural insights into ABC transporter mechanism
- (2008) Michael L Oldham et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Investigating the role of the invariant carboxylate residues E552 and E1197 in the catalytic activity of Abcb1a (mouse Mdr3)
- (2008) Isabelle Carrier et al. FEBS Journal
- Structure, Function, and Evolution of Bacterial ATP-Binding Cassette Systems
- (2008) A. L. Davidson et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- Structure and mechanism of ATP-binding cassette transporters
- (2008) K. P Locher PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Molecular modeling of the human multidrug resistance protein 1 (MRP1/ABCC1)
- (2007) Marianne K. DeGorter et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Seizure-Induced Up-Regulation of P-Glycoprotein at the Blood-Brain Barrier through Glutamate and Cyclooxygenase-2 Signaling
- (2007) B. Bauer et al. MOLECULAR PHARMACOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search