The central cavity of ABCB1 undergoes alternating access during ATP hydrolysis

The Effect of Environment on the Structure of a Membrane Protein: P-Glycoprotein under Physiological Conditions

(2012) Megan L. O’Mara et al.   Journal of Chemical Theory and Computation

Crystal structure of the multidrug transporter P-glycoprotein from Caenorhabditis elegans

(2012) Mi Sun Jin et al.   NATURE

P-glycoprotein Inhibition: The Past, the Present and the Future

(2011) Richard A.J. Darby et al.   CURRENT DRUG METABOLISM

Definition and testing of the GROMOS force-field versions 54A7 and 54B7

(2011) Nathan Schmid et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

An Automated Force Field Topology Builder (ATB) and Repository: Version 1.0

(2011) Alpeshkumar K. Malde et al.   Journal of Chemical Theory and Computation

The Emergence of Drug Transporter-Mediated Multidrug Resistance to Cancer Chemotherapy

(2011) Chung-Pu Wu et al.   MOLECULAR PHARMACEUTICS

Transmembrane helix 12 plays a pivotal role in coupling energy provision and drug binding in ABCB1

(2010) Emily Crowley et al.   FEBS Journal

Transmembrane Helix 12 Modulates Progression of the ATP Catalytic Cycle in ABCB1

(2009) Emily Crowley et al.   BIOCHEMISTRY

Multidrug efflux pumps: drug binding - gates or cavity?

(2009) Emily Crowley et al.   FEBS Journal

Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

(2009) S. G. Aller et al.   SCIENCE

ABC transporters: a riddle wrapped in a mystery inside an enigma

(2009) Peter M. Jones et al.   TRENDS IN BIOCHEMICAL SCIENCES

Cytosolic Region of TM6 in P-Glycoprotein: Topographical Analysis and Functional Perturbation by Site Directed Labeling†

(2008) Janet Storm et al.   BIOCHEMISTRY

Is ATP binding responsible for initiating drug translocation by the multidrug transporter ABCG2?

(2008) Christopher A. McDevitt et al.   FEBS Journal