Multidrug Resistance Protein 1 (MRP1, ABCC1), a “Multitasking” ATP-binding Cassette (ABC) Transporter

GPR55: From orphan to metabolic regulator?

(2015) Bo Liu et al.   PHARMACOLOGY & THERAPEUTICS

High-throughput screening identifies Ceefourin 1 and Ceefourin 2 as highly selective inhibitors of multidrug resistance protein 4 (MRP4)

(2014) Leanna Cheung et al.   BIOCHEMICAL PHARMACOLOGY

A reciprocating twin-channel model for ABC transporters

(2014) Peter M. Jones et al.   QUARTERLY REVIEWS OF BIOPHYSICS

Glutathionylated products of lipid peroxidation

(2014) Brigitte I Frohnert et al.   Adipocyte

Targeting Multidrug Resistance Protein 1 (MRP1, ABCC1): Past, Present, and Future

(2013) Susan P.C. Cole   Annual Review of Pharmacology and Toxicology

Cell death and diseases related to oxidative stress:4-hydroxynonenal (HNE) in the balance

(2013) S Dalleau et al.   CELL DEATH AND DIFFERENTIATION

The expression profile of ATP-binding cassette transporter genes in breast carcinoma

(2013) Viktor Hlaváč et al.   PHARMACOGENOMICS

Cannabinoid- and lysophosphatidylinositol-sensitive receptor GPR55 boosts neurotransmitter release at central synapses

(2013) S. Sylantyev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The actions and metabolism of lysophosphatidylinositol, an endogenous agonist for GPR55

(2013) Atsushi Yamashita et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

The role of multidrug resistance-associated protein in the blood-brain barrier and opioid analgesia

(2013) Wendy Su et al.   SYNAPSE

Ten misconceptions about antioxidants

(2013) Aalt Bast et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Clinicopathological Impact of ABCC1/MRP1 and ABCC4/MRP4 in Epithelial Ovarian Carcinoma

(2013) Marina Bagnoli et al.   Biomed Research International

Lysophosphatidylinositol signalling: New wine from an old bottle

(2012) Roberto Piñeiro et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Mutation of Glu521or Glu535in Cytoplasmic Loop 5 Causes Differential Misfolding in Multiple Domains of Multidrug and Organic Anion Transporter MRP1 (ABCC1)

(2012) Surtaj H. Iram et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mrp1 is Essential for Sphingolipid Signaling to P-Glycoprotein in Mouse Blood–Brain and Blood–Spinal Cord Barriers

(2012) Tara A Cartwright et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Mechanism of RPE Cell Death in α-Crystallin Deficient Mice: A Novel and Critical Role for MRP1-Mediated GSH Efflux

(2012) Parameswaran G. Sreekumar et al.   PLoS One

ABCC1polymorphisms in anthracycline-induced cardiotoxicity in childhood acute lymphoblastic leukaemia

(2011) Agnes F. Semsei et al.   CELL BIOLOGY INTERNATIONAL

ATP-binding cassette ABCC1 is involved in the release of sphingosine 1-phosphate from rat uterine leiomyoma ELT3 cells and late pregnant rat myometrium

(2011) Zahra Tanfin et al.   CELLULAR SIGNALLING

Mammalian multidrug-resistance proteins (MRPs)

(2011) Andrew J. Slot et al.   Essays in Biochemistry

Nitric Oxide Storage and Transport in Cells Are Mediated by GlutathioneS-Transferase P1-1 and Multidrug Resistance Protein 1 via Dinitrosyl Iron Complexes

(2011) Hiu Chuen Lok et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cerebral amyloid-β proteostasis is regulated by the membrane transport protein ABCC1 in mice

(2011) Markus Krohn et al.   JOURNAL OF CLINICAL INVESTIGATION

Pharmacogenomic Prediction of Anthracycline-Induced Cardiotoxicity in Children

(2011) Henk Visscher et al.   JOURNAL OF CLINICAL ONCOLOGY

Natural Vitamin E α-Tocotrienol Protects Against Ischemic Stroke by Induction of Multidrug Resistance-Associated Protein 1

(2011) Han-A Park et al.   STROKE

Chrysin enhances doxorubicin-induced cytotoxicity in human lung epithelial cancer cell lines: The role of glutathione

(2011) Heather M. Brechbuhl et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Sphingosine-1-phosphate signaling and its role in disease

(2011) Michael Maceyka et al.   TRENDS IN CELL BIOLOGY

Leukotriene modifiers for asthma treatment

(2010) P. Montuschi et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Transmembrane helix 12 plays a pivotal role in coupling energy provision and drug binding in ABCB1

(2010) Emily Crowley et al.   FEBS Journal

Location, Location, Location: Compartmentalization of Early Events in Leukotriene Biosynthesis

(2010) Marcia E. Newcomer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression and Function of Human MRP1 (ABCC1) Is Dependent on Amino Acids in Cytoplasmic Loop 5 and Its Interface with Nucleotide Binding Domain 2

(2010) Surtaj H. Iram et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MRP1 Polymorphisms Associated With Citalopram Response in Patients With Major Depression

(2010) Sung Hee Lee et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Inhibition of leukotriene C4 action reduces oxidative stress and apoptosis in cardiomyocytes and impedes remodeling after myocardial injury

(2010) Ulrich M. Becher et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Structure of a human multidrug transporter in an inward-facing conformation

(2010) Mark F. Rosenberg et al.   JOURNAL OF STRUCTURAL BIOLOGY

The putative cannabinoid receptor GPR55 defines a novel autocrine loop in cancer cell proliferation

(2010) R Piñeiro et al.   ONCOGENE

Human Skeletal Muscle Drug Transporters Determine Local Exposure and Toxicity of Statins

(2009) Michael J. Knauer et al.   CIRCULATION RESEARCH

The Role of ABC Transporters in Protecting Cells from Bilirubin Toxicity

(2009) C. Bellarosa et al.   CURRENT PHARMACEUTICAL DESIGN

Molecular Basis for Reduced Estrone Sulfate Transport and Altered Modulator Sensitivity of Transmembrane Helix (TM) 6 and TM17 Mutants of Multidrug Resistance Protein 1 (ABCC1)

(2009) K. Maeno et al.   DRUG METABOLISM AND DISPOSITION

Association of expression of MRP1, BCRP, LRP and ERCC1 with outcome of patients with locally advanced non-small cell lung cancer who received neoadjuvant chemotherapy

(2009) Jian Li et al.   LUNG CANCER

Role of multidrug resistance-associated protein 1 in the pathogenesis of allergic airway inflammation

(2008) Masakata Yoshioka et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Pharmacogenetics of asthma

(2008) John J Lima et al.   CURRENT OPINION IN PULMONARY MEDICINE

Up-regulation and Cytoprotective Role of Epithelial Multidrug Resistance-associated Protein 1 in Inflammatory Bowel Disease

(2008) Hans Blokzijl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plasma membrane glutathione transporters and their roles in cell physiology and pathophysiology

(2008) Nazzareno Ballatori et al.   MOLECULAR ASPECTS OF MEDICINE

Multiple Roles of Charged Amino Acids in Cytoplasmic Loop 7 for Expression and Function of the Multidrug and Organic Anion Transporter MRP1 (ABCC1)

(2008) G. Conseil et al.   MOLECULAR PHARMACOLOGY

Mechanistic Differences between GSH Transport by Multidrug Resistance Protein 1 (MRP1/ABCC1) and GSH Modulation of MRP1-Mediated Transport

(2008) A. Rothnie et al.   MOLECULAR PHARMACOLOGY

Functional Role of Arginine 375 in Transmembrane Helix 6 of Multidrug Resistance Protein 4 (MRP4/ABCC4)

(2008) A. A. K. El-Sheikh et al.   MOLECULAR PHARMACOLOGY

A mutation of the H-loop selectively affects rhodamine transport by the yeast multidrug ABC transporter Pdr5

(2008) Robert Ernst et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular modeling of the human multidrug resistance protein 1 (MRP1/ABCC1)

(2007) Marianne K. DeGorter et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS